Published in J Biol Chem on January 20, 2005
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Molecular drug targets in myeloproliferative neoplasms: mutant ABL1, JAK2, MPL, KIT, PDGFRA, PDGFRB and FGFR1. J Cell Mol Med (2008) 1.10
Trichostatin A causes p53 to switch oxidative-damaged colorectal cancer cells from cell cycle arrest into apoptosis. J Cell Mol Med (2008) 0.95
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Glucocerebrosidase gene-deficient mouse recapitulates Gaucher disease displaying cellular and molecular dysregulation beyond the macrophage. Proc Natl Acad Sci U S A (2010) 1.60
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p53 acetylation is crucial for its transcription-independent proapoptotic functions. J Biol Chem (2009) 1.48
An acetylation switch in p53 mediates holo-TFIID recruitment. Mol Cell (2007) 1.48
Oxytocin is an anabolic bone hormone. Proc Natl Acad Sci U S A (2009) 1.44
Phosphorylation on Thr-55 by TAF1 mediates degradation of p53: a role for TAF1 in cell G1 progression. Mol Cell (2004) 1.44
Serine 15 phosphorylation of p53 directs its interaction with B56gamma and the tumor suppressor activity of B56gamma-specific protein phosphatase 2A. Mol Cell Biol (2007) 1.37
Resveratrol inhibits invasion and metastasis of colorectal cancer cells via MALAT1 mediated Wnt/β-catenin signal pathway. PLoS One (2013) 1.34
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Large-scale expression profiling and physiological characterization of jasmonic acid-mediated adaptation of barley to salinity stress. Plant Cell Environ (2007) 1.22
Glutathione peroxidase 1 is regulated by the c-Abl and Arg tyrosine kinases. J Biol Chem (2003) 1.22
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Safety, biodistribution, and dosimetry of 99mTc-HYNIC-annexin V, a novel human recombinant annexin V for human application. J Nucl Med (2003) 1.14
Motion-compensated hand-held common-path Fourier-domain optical coherence tomography probe for image-guided intervention. Biomed Opt Express (2012) 1.14
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Tanshinone IIA sodium sulfonate protects against cardiotoxicity induced by doxorubicin in vitro and in vivo. Food Chem Toxicol (2009) 1.10
Phytochemical analysis of traditional Chinese medicine using liquid chromatography coupled with mass spectrometry. J Chromatogr A (2008) 1.10
Signal-to-noise ratio analysis of all-fiber common-path optical coherence tomography. Appl Opt (2008) 1.09
Tumour suppressor p53 down-regulates the expression of the human hepatocyte nuclear factor 4alpha (HNF4alpha) gene. Biochem J (2006) 1.09
Transcriptomic signatures in cartilage ageing. Arthritis Res Ther (2013) 1.07
Optical coherence tomography scanning with a handheld vitreoretinal micromanipulator. Conf Proc IEEE Eng Med Biol Soc (2012) 1.07
Genome-wide detection of copy number variations using high-density SNP genotyping platforms in Holsteins. BMC Genomics (2013) 1.06
Investigation into the antioxidant activity and chemical composition of alcoholic extracts from defatted marigold (Tagetes erecta L.) residue. Fitoterapia (2011) 1.06
Interaction of SH2-Bbeta with RET is involved in signaling of GDNF-induced neurite outgrowth. J Cell Sci (2006) 1.06
Proteomics characterization of the cytotoxicity mechanism of ganoderic acid D and computer-automated estimation of the possible drug target network. Mol Cell Proteomics (2007) 1.05
COX-2 contributes to P-glycoprotein-mediated multidrug resistance via phosphorylation of c-Jun at Ser63/73 in colorectal cancer. Carcinogenesis (2011) 1.05
De novo assembly and characterization of Camelina sativa transcriptome by paired-end sequencing. BMC Genomics (2013) 1.04
A comparison of strategies for analyzing dichotomous outcomes in genome-wide association studies with general pedigrees. Genet Epidemiol (2011) 1.04
Anti-tumor activity and apoptosis-regulation mechanisms of bufalin in various cancers: new hope for cancer patients. Asian Pac J Cancer Prev (2012) 1.04
AAV-mediated gene therapy in the guanylate cyclase (RetGC1/RetGC2) double knockout mouse model of Leber congenital amaurosis. Hum Gene Ther (2013) 1.03
Preservation of parotid function with uncomplicated conformal radiotherapy. Radiother Oncol (2002) 1.03
Inhibition of Thr-55 phosphorylation restores p53 nuclear localization and sensitizes cancer cells to DNA damage. Proc Natl Acad Sci U S A (2008) 1.02
Microtubule-binding natural products for cancer therapy. Planta Med (2010) 1.01
Preparation of curcumin-loaded liposomes and evaluation of their skin permeation and pharmacodynamics. Molecules (2012) 1.00
TSP-1 secreted by bone marrow stromal cells contributes to retinal ganglion cell neurite outgrowth and survival. PLoS One (2008) 0.99
Multiple gene mutations, not the type of mutation, are the modifier of left ventricle hypertrophy in patients with hypertrophic cardiomyopathy. Mol Biol Rep (2013) 0.99
Cardio-protection of salvianolic acid B through inhibition of apoptosis network. PLoS One (2011) 0.97
An exotic species is the favorite prey of a native enemy. PLoS One (2011) 0.96
Catalase is regulated by ubiquitination and proteosomal degradation. Role of the c-Abl and Arg tyrosine kinases. Biochemistry (2003) 0.95
Zuo Jin Wan, a Traditional Chinese Herbal Formula, Reverses P-gp-Mediated MDR In Vitro and In Vivo. Evid Based Complement Alternat Med (2013) 0.95
Ruggedness and robustness of conversion factors in method of simultaneous determination of multi-components with single reference standard. J Chromatogr A (2011) 0.94
From a single whole exome read to notions of clinical screening: primary ciliary dyskinesia and RSPH9 p.Lys268del in the Arabian Peninsula. Ann Hum Genet (2012) 0.94
Bufalin-loaded mPEG-PLGA-PLL-cRGD nanoparticles: preparation, cellular uptake, tissue distribution, and anticancer activity. Int J Nanomedicine (2012) 0.94
Spatial Latent Class Analysis Model for Spatially Distributed Multivariate Binary Data. Comput Stat Data Anal (2009) 0.94
Human papillomavirus type 16 E6 and E7 oncoproteins upregulate c-IAP2 gene expression and confer resistance to apoptosis. Oncogene (2005) 0.93
Matrix metalloproteinase-9 induces cardiac fibroblast migration, collagen and cytokine secretion: inhibition by salvianolic acid B from Salvia miltiorrhiza. Phytomedicine (2011) 0.92
Mutations in NEXN, a Z-disc gene, are associated with hypertrophic cardiomyopathy. Am J Hum Genet (2010) 0.92
Antigen-specific T cell functions are suppressed over the estrogen-dendritic cell-indoleamine 2,3-dioxygenase axis. Steroids (2004) 0.92
Identification of DNA-binding proteins by combining auto-cross covariance transformation and ensemble learning. IEEE Trans Nanobioscience (2016) 0.92
Population size and time since island isolation determine genetic diversity loss in insular frog populations. Mol Ecol (2014) 0.91
Selective tropism of the recombinant adeno-associated virus 9 serotype for rat cardiac tissue. J Gene Med (2010) 0.90
Cardioprotection and matrix metalloproteinase-9 regulation of salvianolic acids on myocardial infarction in rats. Planta Med (2009) 0.90
The role of p53 deacetylation in p21Waf1 regulation by laminar flow. J Biol Chem (2003) 0.90
Therapeutic potential of IFN-gamma-modified dendritic cells in acute and chronic experimental allergic encephalomyelitis. Int Immunol (2004) 0.90
Common-Path Optical Coherence Tomography for Biomedical Imaging and Sensing. J Opt Soc Korea (2010) 0.90
Association of estimated glomerular filtration rate and urinary uromodulin concentrations with rare variants identified by UMOD gene region sequencing. PLoS One (2012) 0.89
Improved heterologous gene expression in Trichoderma reesei by cellobiohydrolase I gene (cbh1) promoter optimization. Acta Biochim Biophys Sin (Shanghai) (2008) 0.89
Reduced prefrontal activation during Tower of London in first-episode schizophrenia: a multi-channel near-infrared spectroscopy study. Neurosci Lett (2010) 0.89
Cytotoxic triterpenoids from Ganoderma lucidum. Phytochemistry (2010) 0.89
Interaction of salvianolic acids and notoginsengnosides in inhibition of ADP-induced platelet aggregation. Am J Chin Med (2008) 0.89
A dynamic multiple reaction monitoring method for the multiple components quantification of complex traditional Chinese medicine preparations: Niuhuang Shangqing pill as an example. J Chromatogr A (2013) 0.88
Retrospective survey of museum specimens reveals historically widespread presence of Batrachochytrium dendrobatidis in China. Ecohealth (2014) 0.87
Norcantharidin inhibits tumor angiogenesis via blocking VEGFR2/MEK/ERK signaling pathways. Cancer Sci (2013) 0.87
Ligand-based neutral ruthenium(II) arene complex: selective anticancer action. Inorg Chem (2009) 0.87
Proteomic studies on protective effects of salvianolic acids, notoginsengnosides and combination of salvianolic acids and notoginsengnosides against cardiac ischemic-reperfusion injury. J Ethnopharmacol (2011) 0.86
Salvianolic acid A, a novel matrix metalloproteinase-9 inhibitor, prevents cardiac remodeling in spontaneously hypertensive rats. PLoS One (2013) 0.86
The nucleocapsid protein of severe acute respiratory syndrome coronavirus inhibits cell cytokinesis and proliferation by interacting with translation elongation factor 1alpha. J Virol (2008) 0.86
Hemichorea associated with nonketotic hyperglycemia: clinical and neuroimaging features in 12 patients. Eur Neurol (2014) 0.86
Trends for nanotechnology development in China, Russia, and India. J Nanopart Res (2009) 0.86
CXCR4 down-regulation by small interfering RNA inhibits invasion and tubule formation of human retinal microvascular endothelial cells. Biochem Biophys Res Commun (2007) 0.85
B56γ tumor-associated mutations provide new mechanisms for B56γ-PP2A tumor suppressor activity. Mol Cancer Res (2013) 0.85
[Expression of HIF-1 alpha and its relationship to apoptosis and proliferation in lung cancer]. Ai Zheng (2002) 0.85
Interaction of Ganoderma triterpenes with doxorubicin and proteomic characterization of the possible molecular targets of Ganoderma triterpenes. Cancer Sci (2008) 0.85
Alcohol enhances HIV type 1 infection in normal human oral keratinocytes by up-regulating cell-surface CXCR4 coreceptor. AIDS Res Hum Retroviruses (2004) 0.85
Ca2+/calmodulin-stimulated PDE1 regulates the beta-catenin/TCF signaling through PP2A B56 gamma subunit in proliferating vascular smooth muscle cells. FEBS J (2010) 0.85
Tanshinone II--a inhibits angiogenesis through down regulation of COX-2 in human colorectal cancer. Asian Pac J Cancer Prev (2012) 0.84
Zuo Jin Wan reverses P-gp-mediated drug-resistance by inhibiting activation of the PI3K/Akt/NF-κB pathway. BMC Complement Altern Med (2014) 0.84
PTEN phosphorylation and nuclear export mediate free fatty acid-induced oxidative stress. Antioxid Redox Signal (2013) 0.84
Tastin is required for bipolar spindle assembly and centrosome integrity during mitosis. FASEB J (2008) 0.84
Comparison of two officinal Chinese pharmacopoeia species of Ganoderma based on chemical research with multiple technologies and chemometrics analysis. J Chromatogr A (2011) 0.84
Differential proteomic analysis of platelets suggested possible signal cascades network in platelets treated with salvianolic acid B. PLoS One (2011) 0.84
A single, multi-faceted, enhanced strategy to quantify the chromatographically diverse constituents in the roots of Euphorbia kansui. J Pharm Biomed Anal (2013) 0.83
Synthesis and structure-activity relationships study of cytotoxic bufalin 3-nitrogen-containing-ester derivatives. Steroids (2013) 0.83