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1
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The Oct4 and Nanog transcription network regulates pluripotency in mouse embryonic stem cells.
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Nat Genet
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2006
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20.76
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2
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A global map of p53 transcription-factor binding sites in the human genome.
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Cell
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2006
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20.65
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3
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A pattern-based method for the identification of MicroRNA binding sites and their corresponding heteroduplexes.
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Cell
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2006
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14.70
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4
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MicroRNAs to Nanog, Oct4 and Sox2 coding regions modulate embryonic stem cell differentiation.
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Nature
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2008
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9.83
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5
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Comment on " 'Stemness': transcriptional profiling of embryonic and adult stem cells" and "a stem cell molecular signature".
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Science
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2003
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8.79
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6
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Sall4 modulates embryonic stem cell pluripotency and early embryonic development by the transcriptional regulation of Pou5f1.
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Nat Cell Biol
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2006
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4.81
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7
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Reciprocal transcriptional regulation of Pou5f1 and Sox2 via the Oct4/Sox2 complex in embryonic stem cells.
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Mol Cell Biol
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2005
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4.54
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8
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MicroRNA-125b is a novel negative regulator of p53.
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Genes Dev
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2009
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4.43
|
|
9
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Reprogramming of fibroblasts into induced pluripotent stem cells with orphan nuclear receptor Esrrb.
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Nat Cell Biol
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2009
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4.32
|
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10
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Glycine decarboxylase activity drives non-small cell lung cancer tumor-initiating cells and tumorigenesis.
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Cell
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2012
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3.92
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11
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A genome-wide RNAi screen reveals determinants of human embryonic stem cell identity.
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Nature
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2010
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3.84
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12
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Retinoic acid increases Foxp3+ regulatory T cells and inhibits development of Th17 cells by enhancing TGF-beta-driven Smad3 signaling and inhibiting IL-6 and IL-23 receptor expression.
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J Immunol
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2008
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3.37
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13
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Sall4 interacts with Nanog and co-occupies Nanog genomic sites in embryonic stem cells.
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J Biol Chem
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2006
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3.24
|
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14
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Transcriptome profiling of human and murine ESCs identifies divergent paths required to maintain the stem cell state.
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Stem Cells
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2005
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3.16
|
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15
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MicroRNAs induced during adipogenesis that accelerate fat cell development are downregulated in obesity.
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Diabetes
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2009
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3.02
|
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16
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Distal airway stem cells yield alveoli in vitro and during lung regeneration following H1N1 influenza infection.
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Cell
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2011
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3.00
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17
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miR-200 enhances mouse breast cancer cell colonization to form distant metastases.
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PLoS One
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2009
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2.97
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|
18
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The nuclear receptor Nr5a2 can replace Oct4 in the reprogramming of murine somatic cells to pluripotent cells.
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Cell Stem Cell
|
2010
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2.89
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19
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Tbx3 improves the germ-line competency of induced pluripotent stem cells.
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Nature
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2010
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2.46
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20
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T-cell factor 3 regulates embryonic stem cell pluripotency and self-renewal by the transcriptional control of multiple lineage pathways.
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Stem Cells
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2008
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2.43
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21
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MicroRNA-134 modulates the differentiation of mouse embryonic stem cells, where it causes post-transcriptional attenuation of Nanog and LRH1.
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Stem Cells
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2007
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2.40
|
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22
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Sall4 regulates distinct transcription circuitries in different blastocyst-derived stem cell lineages.
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Cell Stem Cell
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2008
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2.28
|
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23
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Linking beta-catenin to androgen-signaling pathway.
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J Biol Chem
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2002
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2.27
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24
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Eset partners with Oct4 to restrict extraembryonic trophoblast lineage potential in embryonic stem cells.
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Genes Dev
|
2009
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2.18
|
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25
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Derivation of clinically compliant MSCs from CD105+, CD24- differentiated human ESCs.
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Stem Cells
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2006
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2.11
|
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26
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MicroRNA-125b promotes neuronal differentiation in human cells by repressing multiple targets.
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Mol Cell Biol
|
2009
|
2.08
|
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27
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A precarious balance: pluripotency factors as lineage specifiers.
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Cell Stem Cell
|
2011
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2.07
|
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28
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Genome-wide mapping of RELA(p65) binding identifies E2F1 as a transcriptional activator recruited by NF-kappaB upon TLR4 activation.
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Mol Cell
|
2007
|
2.05
|
|
29
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Identification of common pathways mediating differentiation of bone marrow- and adipose tissue-derived human mesenchymal stem cells into three mesenchymal lineages.
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Stem Cells
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2006
|
1.93
|
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30
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Protein kinase C α is a central signaling node and therapeutic target for breast cancer stem cells.
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Cancer Cell
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2013
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1.86
|
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31
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Conserved long noncoding RNAs transcriptionally regulated by Oct4 and Nanog modulate pluripotency in mouse embryonic stem cells.
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RNA
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2009
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1.78
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32
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RCP is a human breast cancer-promoting gene with Ras-activating function.
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J Clin Invest
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2009
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1.71
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33
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The transcriptome of human oocytes.
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Proc Natl Acad Sci U S A
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2006
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1.70
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34
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Conserved regulation of p53 network dosage by microRNA-125b occurs through evolving miRNA-target gene pairs.
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PLoS Genet
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2011
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1.55
|
|
35
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Activin/Nodal signaling controls divergent transcriptional networks in human embryonic stem cells and in endoderm progenitors.
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Stem Cells
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2011
|
1.51
|
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36
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Effects of ectopic Nanog and Oct4 overexpression on mesenchymal stem cells.
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Stem Cells Dev
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2009
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1.32
|
|
37
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B-MYB is essential for normal cell cycle progression and chromosomal stability of embryonic stem cells.
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PLoS One
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2008
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1.32
|
|
38
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Down-regulation of Myc is essential for terminal erythroid maturation.
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J Biol Chem
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2010
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1.30
|
|
39
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hZimp10 is an androgen receptor co-activator and forms a complex with SUMO-1 at replication foci.
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EMBO J
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2003
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1.28
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40
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miR-191 regulates mouse erythroblast enucleation by down-regulating Riok3 and Mxi1.
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Genes Dev
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2010
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1.23
|
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41
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The hematopoiesis-specific GTP-binding protein RhoH is GTPase deficient and modulates activities of other Rho GTPases by an inhibitory function.
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Mol Cell Biol
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2002
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1.20
|
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42
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Graded Nodal/Activin signaling titrates conversion of quantitative phospho-Smad2 levels into qualitative embryonic stem cell fate decisions.
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PLoS Genet
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2011
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1.20
|
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43
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Stage-specific modulation of cortical neuronal development by Mmu-miR-134.
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Cereb Cortex
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2011
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1.19
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44
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Retracted
Autoimmunity as the consequence of a spontaneous mutation in Rasgrp1.
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Immunity
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2003
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1.15
|
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45
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Pleiotrophin enhances clonal growth and long-term expansion of human embryonic stem cells.
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Stem Cells
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2007
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1.12
|
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46
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hZimp7, a novel PIAS-like protein, enhances androgen receptor-mediated transcription and interacts with SWI/SNF-like BAF complexes.
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Mol Endocrinol
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2005
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1.11
|
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47
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ZFP36L2 is required for self-renewal of early burst-forming unit erythroid progenitors.
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Nature
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2013
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1.08
|
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48
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Specific gene-regulation networks during the pre-implantation development of the pig embryo as revealed by deep sequencing.
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BMC Genomics
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2014
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1.04
|
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49
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Recreating pluripotency?
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Cell Stem Cell
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2010
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1.02
|
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50
|
Generation of induced pluripotent stem cells from bovine embryonic fibroblast cells.
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Cell Res
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2011
|
1.02
|
|
51
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Zinc-finger protein 145, acting as an upstream regulator of SOX9, improves the differentiation potential of human mesenchymal stem cells for cartilage regeneration and repair.
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Arthritis Rheum
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2011
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1.00
|
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52
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Inhibition of SARS coronavirus infection in vitro with clinically approved antiviral drugs.
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Emerg Infect Dis
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2004
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0.96
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53
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RhoH is required to maintain the integrin LFA-1 in a nonadhesive state on lymphocytes.
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Nat Immunol
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2004
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0.93
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54
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Enrichment, detection and clinical significance of circulating tumor cells.
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Lab Chip
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2013
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0.92
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55
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Long-term expansion of human functional epidermal precursor cells: promotion of extensive amplification by low TGF-beta1 concentrations.
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J Cell Sci
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2003
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0.91
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56
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RhoH modulates pre-TCR and TCR signalling by regulating LCK.
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Cell Signal
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2010
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0.90
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57
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Molecular basis of immortalization of human mesenchymal stem cells by combination of p53 knockdown and human telomerase reverse transcriptase overexpression.
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Stem Cells Dev
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2012
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0.90
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58
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Human finger-prick induced pluripotent stem cells facilitate the development of stem cell banking.
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Stem Cells Transl Med
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2014
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0.88
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59
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Multiple checkpoint breach of B cell tolerance in Rasgrp1-deficient mice.
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J Immunol
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2013
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0.88
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60
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Induction of functional human macrophages from bone marrow promonocytes by M-CSF in humanized mice.
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J Immunol
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2013
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0.87
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61
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A novel strategy to derive iPS cells from porcine fibroblasts.
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Sci China Life Sci
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2011
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0.86
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62
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RhoH plays distinct roles in T-cell migrations induced by different doses of SDF1 alpha.
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Cell Signal
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2010
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0.85
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63
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Interactions between Notch- and hypoxia-induced transcriptomes in embryonic stem cells.
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Exp Cell Res
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2009
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0.85
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64
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CD14 promoter polymorphisms have no functional significance and are not associated with atopic phenotypes.
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Pharmacogenet Genomics
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2006
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0.85
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65
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CD166(pos) subpopulation from differentiated human ES and iPS cells support repair of acute lung injury.
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Mol Ther
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2012
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0.84
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66
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RhoGTPases and their role in cancer.
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Oncol Res
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2003
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0.84
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67
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Epigenetics: Actors in the cell reprogramming drama.
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Nature
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2012
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0.83
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68
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Elucidating the molecular physiopathology of acute respiratory distress syndrome in severe acute respiratory syndrome patients.
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Virus Res
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2009
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0.82
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69
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ARDS in SARS: cytokine mediators and treatment implications.
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Cytokine
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2005
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0.82
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70
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Glycine decarboxylase is an unusual amino acid decarboxylase involved in tumorigenesis.
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Biochemistry
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2014
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0.80
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71
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Mayven induces c-Jun expression and cyclin D1 activation in breast cancer cells.
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Oncogene
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2005
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0.79
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72
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The molecular basis of ageing in stem cells.
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Mech Ageing Dev
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2006
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0.79
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73
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Reconstitution of mammary epithelial morphogenesis by murine embryonic stem cells undergoing hematopoietic stem cell differentiation.
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PLoS One
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2010
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0.77
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74
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PI3 K/Akt/mTOR-mediated translational control regulates proliferation and differentiation of lineage-restricted RoSH stem cell lines.
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J Mol Signal
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2007
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0.77
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75
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Rejuvenating tithonus.
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EMBO Rep
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2013
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0.75
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76
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Stem cells: Close encounters with full potential.
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Nature
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2013
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0.75
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77
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Characterization of Rho-GDIgamma and Rho-GDIalpha mRNA in the developing and mature brain with an analysis of mice with targeted deletions of Rho-GDIgamma.
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Brain Res
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2005
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0.75
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78
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Corrigendum: Endothelin-1 supports clonal derivation and expansion of cardiovascular progenitors derived from human embryonic stem cells.
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Nat Commun
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2016
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0.75
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79
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Computer and statistical analysis of transcription factor binding and chromatin modifications by ChIP-seq data in embryonic stem cell.
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J Integr Bioinform
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2012
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0.75
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80
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Insights into the role of DNA methylation in murine embryonic stem cells using a modified tetracycline-inducible gene expression system.
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Oncol Res
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2003
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0.75
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