Published in Angew Chem Int Ed Engl on February 18, 2005
Total synthesis of bryostatin 16 using atom-economical and chemoselective approaches. Nature (2008) 2.11
Recent advances in the chemistry and biology of naturally occurring antibiotics. Angew Chem Int Ed Engl (2009) 1.39
Total synthesis of bryostatin 7 via C-C bond-forming hydrogenation. J Am Chem Soc (2011) 1.19
Highly convergent total synthesis of (+)-lithospermic acid via a late-stage intermolecular C-H olefination. J Am Chem Soc (2011) 1.06
Total synthesis of theopederin D. Angew Chem Int Ed Engl (2008) 1.04
A stereoselective synthesis of (+)-herboxidiene/GEX1A. Org Lett (2010) 0.99
The amidohydrolases IAR3 and ILL6 contribute to jasmonoyl-isoleucine hormone turnover and generate 12-hydroxyjasmonic acid upon wounding in Arabidopsis leaves. J Biol Chem (2013) 0.95
A native chemical ligation handle that enables the synthesis of advanced activity-based probes: diubiquitin as a case study. Chembiochem (2014) 0.89
Reversible competitive α-ketoheterocycle inhibitors of fatty acid amide hydrolase containing additional conformational constraints in the acyl side chain: orally active, long-acting analgesics. J Med Chem (2011) 0.87
Total synthesis of bryostatin 16 using a Pd-catalyzed diyne coupling as macrocyclization method and synthesis of C20-epi-bryostatin 7 as a potent anticancer agent. J Am Chem Soc (2010) 0.87
Design and development of stable, water-soluble, human Toll-like receptor 2 specific monoacyl lipopeptides as candidate vaccine adjuvants. J Med Chem (2013) 0.84
Synthesis of antitrypanosomal 1,2-dioxane derivatives based on a natural product scaffold. Bioorg Med Chem Lett (2011) 0.83
Synthesis of the AviMeCys-containing D-ring of mersacidin. Org Lett (2012) 0.83
SAR and Lead Optimization of an HIV-1 Vif-APOBEC3G Axis Inhibitor. ACS Med Chem Lett (2012) 0.82
An efficient synthesis of the tamandarin B macrocycle. Tetrahedron Lett (2010) 0.82
Application of tandem ring-closing enyne metathesis: formal total synthesis of (-)-cochleamycin A. Org Lett (2009) 0.81
Ortho-carbaborane derivatives of indomethacin as cyclooxygenase (COX)-2 selective inhibitors. Bioorg Med Chem (2012) 0.81
Total syntheses of bryostatins: synthesis of two ring-expanded bryostatin analogues and the development of a new-generation strategy to access the C7-C27 fragment. Chemistry (2011) 0.81
Total synthesis and configurational assignment of chondramide A. Chemistry (2010) 0.81
Nitrodibenzofuran: A One- and Two-Photon Sensitive Protecting Group That Is Superior to Brominated Hydroxycoumarin for Thiol Caging in Peptides. J Am Chem Soc (2016) 0.80
The use of 2,2'-dithiobis(5-nitropyridine) (DTNP) for deprotection and diselenide formation in protected selenocysteine-containing peptides. J Pept Sci (2012) 0.79
Development of a hypersensitive periodate-cleavable amino acid that is methionine- and disulfide-compatible and its application in MHC exchange reagents for T cell characterisation. Chembiochem (2013) 0.78
Straightforward protocol for the efficient synthesis of varied N(1)-acylated (aza)indole 2-/3-alkanoic acids and esters: optimization and scale-up. Tetrahedron (2012) 0.78
Synthesis and conformational analysis of bicyclic extended dipeptide surrogates. J Org Chem (2010) 0.78
Concise Total Synthesis of (+)-Luteoalbusins A and B. Org Lett (2015) 0.77
Total synthesis of the antimitotic bicyclic peptide celogentin C. J Am Chem Soc (2010) 0.77
New synthetic technology for the construction of N-hydroxyindoles and synthesis of nocathiacin I model systems. Tetrahedron (2007) 0.76
Enantioselective total synthesis of (+)-lithospermic acid. Org Lett (2012) 0.76
Asymmetric synthesis of chiral cycloalkenone derivatives via palladium catalysis. Chem Sci (2014) 0.76
Total synthesis of (-)-18-epi-peloruside A: an alkyne linchpin strategy. Org Lett (2013) 0.76
Total synthesis of viridicatumtoxin B and analogues thereof: strategy evolution, structural revision, and biological evaluation. J Am Chem Soc (2014) 0.75
How thiostrepton was made in the laboratory. Angew Chem Int Ed Engl (2012) 0.75
Synthesis of the Naturally Occurring (-)-1,3,5-Tri-O-Caffeoylquinic Acid. Synlett (2009) 0.75
Enantioselective total synthesis of (+)-lyngbyabellin m. Mar Drugs (2015) 0.75
Enantioselective Synthesis of (-)-Acetylapoaranotin. Org Lett (2017) 0.75
Chemoenzymatic synthesis of each enantiomer of orthogonally protected 4,4-difluoroglutamic acid: a candidate monomer for chiral Brønsted acid peptide-based catalysts. J Org Chem (2011) 0.75
An enantioselective synthesis of the C3-C21 segment of the macrolide immunosuppressive agent FR252921. Tetrahedron Lett (2016) 0.75
An Enantioselective Synthesis of a MEM-Protected Aetheramide A Derivative. Tetrahedron Lett (2014) 0.75
6-Bromo-7-hydroxy-3-methylcoumarin (mBhc) is an efficient multi-photon labile protecting group for thiol caging and three-dimensional chemical patterning. Org Biomol Chem (2016) 0.75
Evaluation of Chromane-Based Bryostatin Analogues Prepared via Hydrogen-Mediated C-C Bond Formation: Potency Does Not Confer Bryostatin-like Biology. J Am Chem Soc (2016) 0.75
Cascade reactions in total synthesis. Angew Chem Int Ed Engl (2006) 3.03
Chasing molecules that were never there: misassigned natural products and the role of chemical synthesis in modern structure elucidation. Angew Chem Int Ed Engl (2005) 2.35
The continuing saga of the marine polyether biotoxins. Angew Chem Int Ed Engl (2008) 1.67
Ser1292 autophosphorylation is an indicator of LRRK2 kinase activity and contributes to the cellular effects of PD mutations. Sci Transl Med (2012) 1.62
[Risk factors for development and recurrence of peptic ulcer disease]. Korean J Gastroenterol (2010) 1.59
Relationship between intraocular pressure and systemic health parameters in a Korean population. Clin Experiment Ophthalmol (2002) 1.58
Total synthesis of platensimycin. Angew Chem Int Ed Engl (2006) 1.55
Effect of myopia on the thickness of the retinal nerve fiber layer measured by Cirrus HD optical coherence tomography. Invest Ophthalmol Vis Sci (2010) 1.53
Mechanism of MEK inhibition determines efficacy in mutant KRAS- versus BRAF-driven cancers. Nature (2013) 1.52
[Assessment of factors affecting the accuracy of endoscopic ultrasonography in T2 stage gastric cancer]. Korean J Gastroenterol (2008) 1.51
[Effects of proton pump inhibitors in asthmatics with gastroesophageal reflux disease]. Korean J Gastroenterol (2011) 1.42
Recent advances in the chemistry and biology of naturally occurring antibiotics. Angew Chem Int Ed Engl (2009) 1.39
Total synthesis of thiostrepton. Retrosynthetic analysis and construction of key building blocks. J Am Chem Soc (2005) 1.30
Oxidation of silyl enol ethers by using IBX and IBX.N-oxide complexes: a mild and selective reaction for the synthesis of enones. Angew Chem Int Ed Engl (2002) 1.27
Total synthesis of thiostrepton. Assembly of key building blocks and completion of the synthesis. J Am Chem Soc (2005) 1.26
The effects of probiotics on PPI-triple therapy for Helicobacter pylori eradication. Helicobacter (2008) 1.23
Discovery of a biologically active thiostrepton fragment. J Am Chem Soc (2005) 1.20
Total syntheses of 2,2'-epi-cytoskyrin A, rugulosin, and the alleged structure of rugulin. J Am Chem Soc (2007) 1.19
Total synthesis of 1-O-methyllateriflorone. Angew Chem Int Ed Engl (2003) 1.17
Total syntheses and structural revision of alpha- and beta-diversonolic esters and total syntheses of diversonol and blennolide C. Angew Chem Int Ed Engl (2008) 1.16
Total synthesis and structural elucidation of azaspiracid-1. Final assignment and total synthesis of the correct structure of azaspiracid-1. J Am Chem Soc (2006) 1.12
Chemical synthesis of the GHIJK ring system and further experimental support for the originally assigned structure of maitotoxin. Angew Chem Int Ed Engl (2007) 1.12
Identification of imidazo-pyrrolopyridines as novel and potent JAK1 inhibitors. J Med Chem (2012) 1.10
Asymmetric total syntheses of platensimycin. Angew Chem Int Ed Engl (2007) 1.10
Total synthesis of apoptolidin: construction of enantiomerically pure fragments. J Am Chem Soc (2003) 1.09
On the structure of maitotoxin. Angew Chem Int Ed Engl (2007) 1.08
Synthesis of the sporolide ring framework through a cascade sequence involving an intramolecular [4+2] cycloaddition reaction of an o-quinone. Angew Chem Int Ed Engl (2008) 1.08
Total synthesis and revised structure of biyouyanagin A. Angew Chem Int Ed Engl (2007) 1.07
Total synthesis of hirsutellone B. Angew Chem Int Ed Engl (2009) 1.07
Total synthesis and confirmation of the revised structures of azaspiracid-2 and azaspiracid-3. Angew Chem Int Ed Engl (2006) 1.06
Total synthesis of platencin. Angew Chem Int Ed Engl (2008) 1.05
Total synthesis of apoptolidin: completion of the synthesis and analogue synthesis and evaluation. J Am Chem Soc (2003) 1.05
Sustained-release praziquantel tablet: pharmacokinetics and the treatment of clonorchiasis in beagle dogs. Parasitol Res (2003) 1.02
An expedient synthesis of a functionalized core structure of bielschowskysin. Angew Chem Int Ed Engl (2011) 1.01
Modulation of the reactivity profile of IBX by ligand complexation: ambient temperature dehydrogenation of aldehydes and ketones to alpha,beta-unsaturated carbonyl compounds. Angew Chem Int Ed Engl (2002) 0.99
Total synthesis and structural elucidation of azaspiracid-1. Synthesis-based analysis of originally proposed structures and indication of their non-identity to the natural product. J Am Chem Soc (2006) 0.97
Relationship between intraocular pressure and systemic health parameters in the Korean population. Korean J Ophthalmol (2002) 0.96
Discovery and preclinical pharmacology of a selective ATP-competitive Akt inhibitor (GDC-0068) for the treatment of human tumors. J Med Chem (2012) 0.96
Total synthesis and structural elucidation of azaspiracid-1. Construction of key building blocks for originally proposed structure. J Am Chem Soc (2006) 0.95
Universal solid-phase approach for the immobilization, derivatization, and resin-to-resin transfer reactions of boronic acids. J Org Chem (2002) 0.93
Acute toxicity of Ag and CuO nanoparticle suspensions against Daphnia magna: the importance of their dissolved fraction varying with preparation methods. J Hazard Mater (2012) 0.93
A practical sulfenylation of 2,5-diketopiperazines. Angew Chem Int Ed Engl (2011) 0.92
Total synthesis of thiostrepton, part 2: construction of the quinaldic acid macrocycle and final stages of the synthesis. Angew Chem Int Ed Engl (2004) 0.91
Second-generation total synthesis of azaspiracids-1, -2, and -3. Chem Asian J (2006) 0.90
Discovery of selective LRRK2 inhibitors guided by computational analysis and molecular modeling. J Med Chem (2012) 0.90
Structure-based discovery of novel amide-containing nicotinamide phosphoribosyltransferase (nampt) inhibitors. J Med Chem (2013) 0.89
Revision total hip arthroplasty using an extensively porous coated femoral stem. Clin Orthop Surg (2009) 0.87
A biomimetically inspired synthesis of the dehydropiperidine domain of thiostrepton. Angew Chem Int Ed Engl (2002) 0.86
Total synthesis of marinomycins A-C. Angew Chem Int Ed Engl (2006) 0.86
Total synthesis of thiostrepton, part 1: construction of the dehydropiperidine/thiazoline-containing macrocycle. Angew Chem Int Ed Engl (2004) 0.86
New reactions of IBX: oxidation of nitrogen- and sulfur-containing substrates to afford useful synthetic intermediates. Angew Chem Int Ed Engl (2003) 0.86
Structure-based identification of ureas as novel nicotinamide phosphoribosyltransferase (Nampt) inhibitors. J Med Chem (2013) 0.86
Preclinical disposition and pharmacokinetics-pharmacodynamic modeling of biomarker response and tumour growth inhibition in xenograft mouse models of G-573, a MEK inhibitor. Xenobiotica (2010) 0.84
The CP molecule labyrinth: a paradigm of how endeavors in total synthesis lead to discoveries and inventions in organic synthesis. Angew Chem Int Ed Engl (2002) 0.83
Construction of substituted N-hydroxyindoles: synthesis of a nocathiacin I model system. Angew Chem Int Ed Engl (2005) 0.83
A restricted role for TYK2 catalytic activity in human cytokine responses revealed by novel TYK2-selective inhibitors. J Immunol (2013) 0.83
Potent and selective inhibitors of PI3Kδ: obtaining isoform selectivity from the affinity pocket and tryptophan shelf. Bioorg Med Chem Lett (2012) 0.83
A case of inadvertent anterior chamber and corneal stromal injection with antibiotics during cataract operation. Korean J Ophthalmol (2006) 0.82
Total synthesis and biological evaluation of (-)apicularen A and analogues thereof. Chemistry (2003) 0.82
[Clinical characteristics of patients diagnosed as peptic ulcer disease in the third referral center in 2007]. Korean J Gastroenterol (2012) 0.82
Long-term follow up of Helicobacter pylori IgG serology after eradication and reinfection rate of H. pylori in South Korea. Helicobacter (2008) 0.82
Fragment-based identification of amides derived from trans-2-(pyridin-3-yl)cyclopropanecarboxylic acid as potent inhibitors of human nicotinamide phosphoribosyltransferase (NAMPT). J Med Chem (2014) 0.81
Identification of amides derived from 1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid as potent inhibitors of human nicotinamide phosphoribosyltransferase (NAMPT). Bioorg Med Chem Lett (2013) 0.81
Synthesis of highly substituted N-hydroxyindoles through 1,5-addition of carbon nucleophiles to in situ generated unsaturated nitrones. Angew Chem Int Ed Engl (2006) 0.81
Synthetic studies on thiostrepton: construction of thiostrepton analogues with the thiazoline-containing macrocycle. Angew Chem Int Ed Engl (2003) 0.80
[A case of intestinal tuberculosis presenting massive hematochezia controlled by endoscopic coagulation therapy]. Korean J Gastroenterol (2005) 0.80
Total synthesis and stereochemistry of uncialamycin. Angew Chem Int Ed Engl (2007) 0.80
A new entry of copper-catalyzed four-component reaction: facile access to alpha-aryl beta-hydroxy imidates. Org Lett (2009) 0.80
Discovery of dual leucine zipper kinase (DLK, MAP3K12) inhibitors with activity in neurodegeneration models. J Med Chem (2014) 0.79
Studies on activation mechanism of a mitomycin dimer, 7-N,7'-N'-(1″,2″-dithiepanyl-3″,7″-dimethylenyl)bismitomycin C. Arch Pharm Res (2012) 0.79
A new method for the synthesis of nonsymmetrical sulfamides using burgess-type reagents. Angew Chem Int Ed Engl (2002) 0.78
Ethanol potentiates hepatitis B virus replication through oxidative stress-dependent and -independent transcriptional activation. Biochem Biophys Res Commun (2012) 0.78
Synthesis of macroheterocycles through intramolecular oxidative coupling of furanoid β-ketoesters. Angew Chem Int Ed Engl (2012) 0.78
Structural and biochemical analyses of the catalysis and potency impact of inhibitor phosphoribosylation by human nicotinamide phosphoribosyltransferase. Chembiochem (2014) 0.77
Cascade reactions involving formal [2+2] thermal cycloadditions: total synthesis of artochamins F, H, I, and J. Angew Chem Int Ed Engl (2007) 0.77
Relationship between the retinal thickness analyzer and the GDx VCC scanning laser polarimeter, Stratus OCT optical coherence tomograph, and Heidelberg retina tomograph II confocal scanning laser ophthalmoscopy. Korean J Ophthalmol (2008) 0.77
Synthesis and mechanistic studies of a mitomycin dimer containing an eight-membered cyclic disulfide. Bioorg Med Chem (2011) 0.77
Asymmetric synthesis and biological properties of uncialamycin and 26-epi-uncialamycin. Angew Chem Int Ed Engl (2008) 0.77
An expedient strategy for the synthesis of tryptamines and other heterocycles. Angew Chem Int Ed Engl (2008) 0.77