Published in Hum Reprod on February 10, 2005
Role of HRB in clathrin-dependent endocytosis. J Biol Chem (2008) 1.28
Fast forward to new genes in mammalian reproduction. J Physiol (2006) 0.87
Galnt3 deficiency disrupts acrosome formation and leads to oligoasthenoteratozoospermia. Histochem Cell Biol (2012) 0.84
The LINC complex component Sun4 plays a crucial role in sperm head formation and fertility. Biol Open (2015) 0.84
The Arf GAP SMAP2 is necessary for organized vesicle budding from the trans-Golgi network and subsequent acrosome formation in spermiogenesis. Mol Biol Cell (2013) 0.79
Ultrastructural Morphology of Sperm from Human Globozoospermia. Biomed Res Int (2015) 0.75
Differential sensitivity of mouse strains to an N-alkylated imino sugar: glycosphingolipid metabolism and acrosome formation. Pharmacogenomics (2008) 0.75
Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders. Nature (2011) 8.45
BubR1 insufficiency causes early onset of aging-associated phenotypes and infertility in mice. Nat Genet (2004) 6.85
Rae1 is an essential mitotic checkpoint regulator that cooperates with Bub3 to prevent chromosome missegregation. J Cell Biol (2003) 3.40
Opposing roles for p16Ink4a and p19Arf in senescence and ageing caused by BubR1 insufficiency. Nat Cell Biol (2008) 2.81
Bub1 mediates cell death in response to chromosome missegregation and acts to suppress spontaneous tumorigenesis. J Cell Biol (2007) 2.69
BubR1 N terminus acts as a soluble inhibitor of cyclin B degradation by APC/C(Cdc20) in interphase. Dev Cell (2009) 2.69
Plk1-dependent phosphorylation of FoxM1 regulates a transcriptional programme required for mitotic progression. Nat Cell Biol (2008) 2.68
Whole chromosome instability caused by Bub1 insufficiency drives tumorigenesis through tumor suppressor gene loss of heterozygosity. Cancer Cell (2009) 2.58
A transcription-factor-binding surface of coactivator p300 is required for haematopoiesis. Nature (2002) 2.50
The Rae1-Nup98 complex prevents aneuploidy by inhibiting securin degradation. Nature (2005) 2.33
Resolution of sister centromeres requires RanBP2-mediated SUMOylation of topoisomerase IIalpha. Cell (2008) 2.25
Whole chromosome instability and cancer: a complex relationship. Trends Genet (2008) 2.04
The ATM-p53 pathway suppresses aneuploidy-induced tumorigenesis. Proc Natl Acad Sci U S A (2010) 1.98
Increased expression of BubR1 protects against aneuploidy and cancer and extends healthy lifespan. Nat Cell Biol (2012) 1.94
Direct interaction between SET8 and proliferating cell nuclear antigen couples H4-K20 methylation with DNA replication. J Biol Chem (2008) 1.93
Overexpression of the E2 ubiquitin-conjugating enzyme UbcH10 causes chromosome missegregation and tumor formation. J Cell Biol (2010) 1.60
Mutant mice with small amounts of BubR1 display accelerated age-related gliosis. Neurobiol Aging (2006) 1.40
Induction of prostatic intraepithelial neoplasia and modulation of androgen receptor by ETS variant 1/ETS-related protein 81. Cancer Res (2009) 1.39
Cdc20 hypomorphic mice fail to counteract de novo synthesis of cyclin B1 in mitosis. J Cell Biol (2010) 1.38
Bub1 overexpression induces aneuploidy and tumor formation through Aurora B kinase hyperactivation. J Cell Biol (2011) 1.35
Aging-associated vascular phenotype in mutant mice with low levels of BubR1. Stroke (2007) 1.35
p21 both attenuates and drives senescence and aging in BubR1 progeroid mice. Cell Rep (2013) 1.19
Securin associates with APCCdh1 in prometaphase but its destruction is delayed by Rae1 and Nup98 until the metaphase/anaphase transition. Cell Cycle (2006) 1.17
Bub1 kinase activity drives error correction and mitotic checkpoint control but not tumor suppression. J Cell Biol (2012) 1.14
CREB binding protein is required for both short-term and long-term memory formation. J Neurosci (2010) 1.14
Gene targeting methods for studying nuclear transport factors in mice. Methods (2006) 1.14
Aneuploidy in health, disease, and aging. J Cell Biol (2013) 1.13
In vivo SILAC-based proteomics reveals phosphoproteome changes during mouse skin carcinogenesis. Cell Rep (2013) 1.11
Cdc20 is critical for meiosis I and fertility of female mice. PLoS Genet (2010) 1.11
Epitope-tagged Pkhd1 tracks the processing, secretion, and localization of fibrocystin. J Am Soc Nephrol (2011) 1.09
Ran-dependent docking of importin-beta to RanBP2/Nup358 filaments is essential for protein import and cell viability. J Cell Biol (2011) 1.07
Reduced life- and healthspan in mice carrying a mono-allelic BubR1 MVA mutation. PLoS Genet (2012) 0.96
Aurora B hyperactivation by Bub1 overexpression promotes chromosome missegregation. Cell Cycle (2011) 0.94
CAML loss causes anaphase failure and chromosome missegregation. Cell Cycle (2009) 0.92
Chromosome missegregation causes colon cancer by APC loss of heterozygosity. Cell Cycle (2010) 0.92
Nuclear pore protein NUP88 activates anaphase-promoting complex to promote aneuploidy. J Clin Invest (2016) 0.91
Activation of the transforming growth factor-β/SMAD transcriptional pathway underlies a novel tumor-promoting role of sulfatase 1 in hepatocellular carcinoma. Hepatology (2015) 0.90
The yin and yang of the Cdkn2a locus in senescence and aging. Cell Cycle (2008) 0.85
Smoothelin-B deficiency results in reduced arterial contractility, hypertension, and cardiac hypertrophy in mice. Circulation (2008) 0.84
The role of mitotic checkpoint in maintaining genomic stability. Curr Top Dev Biol (2003) 0.83
Reprogramming to pluripotency can conceal somatic cell chromosomal instability. PLoS Genet (2012) 0.82
Transgenesis in mouse embryonic stem cells. Methods Mol Biol (2011) 0.81
Histone demethylase JMJD2A drives prostate tumorigenesis through transcription factor ETV1. J Clin Invest (2016) 0.80
Correction of microtubule-kinetochore attachment errors: mechanisms and role in tumor suppression. Semin Cell Dev Biol (2011) 0.79
Sgo1 as a "guardian spirit" for preventing colon tumorigenesis. Cell Cycle (2012) 0.76
Why do we grow old: is it because our cells just wear out, we run out of cells (or both), and what can we do about it? Longev Healthspan (2013) 0.75