Published in Cell Cycle on February 15, 2006
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Chromosome missegregation causes colon cancer by APC loss of heterozygosity. Cell Cycle (2010) 0.92
Nuclear pore protein NUP88 activates anaphase-promoting complex to promote aneuploidy. J Clin Invest (2016) 0.91
Identification of novel deregulated RNA metabolism-related genes in non-small cell lung cancer. PLoS One (2012) 0.88
Multi-layered cancer chromosomal instability phenotype. Front Oncol (2013) 0.88
The yin and yang of the Cdkn2a locus in senescence and aging. Cell Cycle (2008) 0.85
Targeting karyotypic complexity and chromosomal instability of cancer cells. Curr Drug Targets (2010) 0.84
A translational regulator, PUM2, promotes both protein stability and kinase activity of Aurora-A. PLoS One (2011) 0.84
Learning about cancer from frogs: analysis of mitotic spindles in Xenopus egg extracts. Dis Model Mech (2009) 0.84
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Non-FG mediated transport of the large pre-ribosomal subunit through the nuclear pore complex by the mRNA export factor Gle2. Nucleic Acids Res (2013) 0.77
Nup2 requires a highly divergent partner, NupA, to fulfill functions at nuclear pore complexes and the mitotic chromatin region. Mol Biol Cell (2014) 0.77
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Functional analysis of the NUP98-CCDC28A fusion protein. Haematologica (2011) 0.76
The Hippo Pathway Targets Rae1 to Regulate Mitosis and Organ Size and to Feed Back to Regulate Upstream Components Merlin, Hippo, and Warts. PLoS Genet (2016) 0.75
Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders. Nature (2011) 8.45
BubR1 insufficiency causes early onset of aging-associated phenotypes and infertility in mice. Nat Genet (2004) 6.85
Rae1 is an essential mitotic checkpoint regulator that cooperates with Bub3 to prevent chromosome missegregation. J Cell Biol (2003) 3.40
Opposing roles for p16Ink4a and p19Arf in senescence and ageing caused by BubR1 insufficiency. Nat Cell Biol (2008) 2.81
Bub1 mediates cell death in response to chromosome missegregation and acts to suppress spontaneous tumorigenesis. J Cell Biol (2007) 2.69
BubR1 N terminus acts as a soluble inhibitor of cyclin B degradation by APC/C(Cdc20) in interphase. Dev Cell (2009) 2.69
Plk1-dependent phosphorylation of FoxM1 regulates a transcriptional programme required for mitotic progression. Nat Cell Biol (2008) 2.68
Whole chromosome instability caused by Bub1 insufficiency drives tumorigenesis through tumor suppressor gene loss of heterozygosity. Cancer Cell (2009) 2.58
A transcription-factor-binding surface of coactivator p300 is required for haematopoiesis. Nature (2002) 2.50
The Rae1-Nup98 complex prevents aneuploidy by inhibiting securin degradation. Nature (2005) 2.33
Resolution of sister centromeres requires RanBP2-mediated SUMOylation of topoisomerase IIalpha. Cell (2008) 2.25
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The ATM-p53 pathway suppresses aneuploidy-induced tumorigenesis. Proc Natl Acad Sci U S A (2010) 1.98
Increased expression of BubR1 protects against aneuploidy and cancer and extends healthy lifespan. Nat Cell Biol (2012) 1.94
Direct interaction between SET8 and proliferating cell nuclear antigen couples H4-K20 methylation with DNA replication. J Biol Chem (2008) 1.93
Loss of CBP causes T cell lymphomagenesis in synergy with p27Kip1 insufficiency. Cancer Cell (2004) 1.80
Overexpression of the E2 ubiquitin-conjugating enzyme UbcH10 causes chromosome missegregation and tumor formation. J Cell Biol (2010) 1.60
Mutant mice with small amounts of BubR1 display accelerated age-related gliosis. Neurobiol Aging (2006) 1.40
Induction of prostatic intraepithelial neoplasia and modulation of androgen receptor by ETS variant 1/ETS-related protein 81. Cancer Res (2009) 1.39
Cdc20 hypomorphic mice fail to counteract de novo synthesis of cyclin B1 in mitosis. J Cell Biol (2010) 1.38
Bub1 overexpression induces aneuploidy and tumor formation through Aurora B kinase hyperactivation. J Cell Biol (2011) 1.35
Aging-associated vascular phenotype in mutant mice with low levels of BubR1. Stroke (2007) 1.35
p21 both attenuates and drives senescence and aging in BubR1 progeroid mice. Cell Rep (2013) 1.19
CREB binding protein is required for both short-term and long-term memory formation. J Neurosci (2010) 1.14
Gene targeting methods for studying nuclear transport factors in mice. Methods (2006) 1.14
Bub1 kinase activity drives error correction and mitotic checkpoint control but not tumor suppression. J Cell Biol (2012) 1.14
Aneuploidy in health, disease, and aging. J Cell Biol (2013) 1.13
In vivo SILAC-based proteomics reveals phosphoproteome changes during mouse skin carcinogenesis. Cell Rep (2013) 1.11
Cdc20 is critical for meiosis I and fertility of female mice. PLoS Genet (2010) 1.11
Epitope-tagged Pkhd1 tracks the processing, secretion, and localization of fibrocystin. J Am Soc Nephrol (2011) 1.09
Ran-dependent docking of importin-beta to RanBP2/Nup358 filaments is essential for protein import and cell viability. J Cell Biol (2011) 1.07
Reduced life- and healthspan in mice carrying a mono-allelic BubR1 MVA mutation. PLoS Genet (2012) 0.96
Aurora B hyperactivation by Bub1 overexpression promotes chromosome missegregation. Cell Cycle (2011) 0.94
CAML loss causes anaphase failure and chromosome missegregation. Cell Cycle (2009) 0.92
Chromosome missegregation causes colon cancer by APC loss of heterozygosity. Cell Cycle (2010) 0.92
Nuclear pore protein NUP88 activates anaphase-promoting complex to promote aneuploidy. J Clin Invest (2016) 0.91
Activation of the transforming growth factor-β/SMAD transcriptional pathway underlies a novel tumor-promoting role of sulfatase 1 in hepatocellular carcinoma. Hepatology (2015) 0.90
The yin and yang of the Cdkn2a locus in senescence and aging. Cell Cycle (2008) 0.85
A mouse model of familial oligoasthenoteratozoospermia. Hum Reprod (2005) 0.84
Smoothelin-B deficiency results in reduced arterial contractility, hypertension, and cardiac hypertrophy in mice. Circulation (2008) 0.84
The role of mitotic checkpoint in maintaining genomic stability. Curr Top Dev Biol (2003) 0.83
Reprogramming to pluripotency can conceal somatic cell chromosomal instability. PLoS Genet (2012) 0.82
Transgenesis in mouse embryonic stem cells. Methods Mol Biol (2011) 0.81
Histone demethylase JMJD2A drives prostate tumorigenesis through transcription factor ETV1. J Clin Invest (2016) 0.80
Correction of microtubule-kinetochore attachment errors: mechanisms and role in tumor suppression. Semin Cell Dev Biol (2011) 0.79
Sgo1 as a "guardian spirit" for preventing colon tumorigenesis. Cell Cycle (2012) 0.76
Why do we grow old: is it because our cells just wear out, we run out of cells (or both), and what can we do about it? Longev Healthspan (2013) 0.75