Published in J Immunol on March 01, 2005
Progress and problems in the application of focused ultrasound for blood-brain barrier disruption. Ultrasonics (2008) 1.42
Targeting C-type lectin-like molecule-1 for antibody-mediated immunotherapy in acute myeloid leukemia. Haematologica (2009) 1.03
Implications of IV monoclonal antibody infusion reaction for the patient, caregiver, and practice: results of a multicenter study. Support Care Cancer (2008) 0.98
Engineered cell surface expression of membrane immunoglobulin as a means to identify monoclonal antibody-secreting hybridomas. J Immunol Methods (2009) 0.89
Development of broad-spectrum human monoclonal antibodies for rabies post-exposure prophylaxis. EMBO Mol Med (2016) 0.85
Generation of antibody-producing hybridomas following one single immunization with a targeted DNA vaccine. Scand J Immunol (2012) 0.84
An EGFRvIII-targeted bispecific T-cell engager overcomes limitations of the standard of care for glioblastoma. Expert Rev Clin Pharmacol (2013) 0.84
Monoclonal antibodies: producing magic bullets by somatic cell hybridization. J Immunol (2005) 0.82
CD19 chimeric antigen receptor (CD19 CAR)-redirected adoptive T-cell immunotherapy for the treatment of relapsed or refractory B-cell Non-Hodgkin's Lymphomas. Am J Cancer Res (2016) 0.81
Production, Characterization, and Use of Monoclonal Antibodies Against gp51 Protein to Diagnose Bovine Leukemia Virus Infection. Biores Open Access (2013) 0.79
Generation of “LYmph Node Derived Antibody Libraries” (LYNDAL) for selecting fully human antibody fragments with therapeutic potential. MAbs (2014) 0.76
A simple, rapid and sensitive FRET assay for botulinum neurotoxin serotype B detection. PLoS One (2014) 0.75
Tumour inflammatory response: adding fuel to the fire? Curr Oncol (2015) 0.75
Antibody therapy of pediatric B-cell lymphoma. Front Oncol (2013) 0.75
Monoclonal antibodies specific to human Δ42PD1: A novel immunoregulator potentially involved in HIV-1 and tumor pathogenesis. MAbs (2015) 0.75
Production of monoclonal antibodies against serum immunoglobulins of black rockfish (Sebastes schlegeli Higendorf). J Vet Sci (2006) 0.75
New model for cardiomyocyte sheet transplantation using a virus-cell fusion technique. World J Stem Cells (2015) 0.75
Intracellular trafficking of new anticancer therapeutics: antibody-drug conjugates. Drug Des Devel Ther (2017) 0.75
Preferential production of IgM-secreting hybridomas by immunization with DNA vaccines coding for Ebola virus glycoprotein: use of protein boosting for IgG-secreting hybridoma production. Clin Exp Vaccine Res (2017) 0.75
Continuous cultures of fused cells secreting antibody of predefined specificity. Nature (1975) 83.56
Derivation of specific antibody-producing tissue culture and tumor lines by cell fusion. Eur J Immunol (1976) 30.70
Antibodies to major histocompatibility antigens produced by hybrid cell lines. Nature (1977) 16.54
A better cell line for making hybridomas secreting specific antibodies. Nature (1978) 15.13
Production of monoclonal antibodies to group A erythrocytes, HLA and other human cell surface antigens-new tools for genetic analysis. Cell (1978) 14.82
Preparation of monoclonal antibodies: strategies and procedures. Methods Enzymol (1981) 14.45
A possible precursor of immunoglobulin light chains. Nat New Biol (1972) 11.03
Mac-1: a macrophage differentiation antigen identified by monoclonal antibody. Eur J Immunol (1979) 10.51
Rat monoclonal antitubulin antibodies derived by using a new nonsecreting rat cell line. J Cell Biol (1982) 9.66
Impaired immune and acute-phase responses in interleukin-6-deficient mice. Nature (1994) 8.85
Analysis of cell surfaces by xenogeneic myeloma-hybrid antibodies: differentiation antigens of rat lymphocytes. Cell (1977) 8.46
Complete sequence of constant and 3' noncoding regions of an immunoglobulin mRNA using the dideoxynucleotide method of RNA sequencing. Cell (1978) 8.20
Fusion between immunoglobulin-secreting and nonsecreting myeloma cell lines. Eur J Immunol (1976) 7.64
Disruption of the murine IL-4 gene blocks Th2 cytokine responses. Nature (1993) 6.54
Rat x rat hybrid myelomas and a monoclonal anti-Fd portion of mouse IgG. Nature (1979) 5.69
Monoclonal xenogeneic antibodies to murine cell surface antigens: identification of novel leukocyte differentiation antigens. Eur J Immunol (1978) 5.35
A human thymocyte antigen defined by a hybrid myeloma monoclonal antibody. Eur J Immunol (1979) 5.17
Isolation of a fragment of tau derived from the core of the paired helical filament of Alzheimer disease. Proc Natl Acad Sci U S A (1988) 4.45
Somatic mutation and the maturation of immune response to 2-phenyl oxazolone. Nature (1984) 4.45
Mutation drift and repertoire shift in the maturation of the immune response. Immunol Rev (1987) 4.16
Man-made antibodies. Nature (1991) 3.88
Origin of antibody variation. Nature (1966) 3.50
Assembly and secretion of heavy chains that do not associate posttranslationally with immunoglobulin heavy chain-binding protein. J Cell Biol (1987) 3.33
Kinetic maturation of an immune response. Nature (1991) 3.26
Consequences of frameshift mutations at the immunoglobulin heavy chain locus of the mouse. EMBO J (1985) 3.25
IL-5-deficient mice have a developmental defect in CD5+ B-1 cells and lack eosinophilia but have normal antibody and cytotoxic T cell responses. Immunity (1996) 3.23
T-lymphocyte heterogeneity in the rat: separation of functional subpopulations using a monoclonal antibody. J Exp Med (1978) 3.20
Hot spot focusing of somatic hypermutation in MSH2-deficient mice suggests two stages of mutational targeting. Immunity (1998) 3.16
Linked groups of residues in immunoglobulin k chains. Nature (1967) 3.12
Elements regulating somatic hypermutation of an immunoglobulin kappa gene: critical role for the intron enhancer/matrix attachment region. Cell (1994) 3.06
The complete amino acid sequence of a mouse kappa light chain. Biochem J (1972) 2.94
Molecular events during maturation of the immune response to oxazolone. Nature (1985) 2.78
Cutting edge: lymphoproliferative disease in the absence of CTLA-4 is not T cell autonomous. J Immunol (1999) 2.77
mRNA sequences define an unusually restricted IgG response to 2-phenyloxazolone and its early diversification. Nature (1983) 2.72
Structural studies of immunoglobulin G. Nature (1969) 2.63
Interleukin-12 is essential for a protective Th1 response in mice infected with Cryptococcus neoformans. Infect Immun (1998) 2.60
Variations in the S-S bridges of immunoglobins G: interchain disulfide bridges of gamma G3 myeloma proteins. J Mol Biol (1968) 2.57
An immunoglobulin deletion mutant with implications for the heavy-chain switch and RNA splicing. Nature (1980) 2.41
CD22 is a negative regulator of B-cell receptor signalling. Curr Biol (1997) 2.37
Deletions in immunoglobulin mu chains. EMBO J (1982) 2.35
Differences between IL-4- and IL-4 receptor alpha-deficient mice in chronic leishmaniasis reveal a protective role for IL-13 receptor signaling. J Immunol (1999) 2.33
Passenger transgenes reveal intrinsic specificity of the antibody hypermutation mechanism: clustering, polarity, and specific hot spots. Proc Natl Acad Sci U S A (1993) 2.30
Transitional B cells are the target of negative selection in the B cell compartment. J Exp Med (1995) 2.26
Hybrid hybridomas and their use in immunohistochemistry. Nature (1983) 2.24
Efficient targeting of the IL-4 gene in a BALB/c embryonic stem cell line. Transgenic Res (1996) 2.23
Sequence analysis of immunoglobulin light chain messenger RNA. Nature (1974) 2.22
A novel family of human major histocompatibility complex-related genes not mapping to chromosome 6. Nature (1986) 2.22
Detection of substance P in the central nervous system by a monoclonal antibody. Proc Natl Acad Sci U S A (1979) 2.16
Complete sequence of an immunoglobulin mRNA using specific priming and the dideoxynucleotide method of RNA sequencing. Nucleic Acids Res (1981) 2.16
Variations in amino-acid sequence near the disulphide bridges of Bence-Jones proteins. Nature (1966) 2.14
Intracellular immunoglobulin chain synthesis in non-secreting variants of a mouse myeloma: detection of inactive light-chain messenger RNA. J Mol Biol (1974) 2.14
Developmental regulation of IgM secretion: the role of the carboxy-terminal cysteine. Cell (1990) 2.12
Human immunoglobulin subclasses. Partial amino acid sequence of the constant region of a gamma 4 chain. Biochem J (1970) 2.11
Two classes of CD1 genes. Eur J Immunol (1989) 2.11
Structure and biological properties of immunoglobulins. Adv Immunol (1967) 2.08
The dynamic nature of the antibody repertoire. Immunol Rev (1988) 2.08
Transmission and expression of a specific pair of rearranged immunoglobulin mu and kappa genes in a transgenic mouse line. Nature (1985) 2.08
Somatic hypermutation. Curr Opin Immunol (1995) 2.08
IL-4-deficient Balb/c mice resist infection with Leishmania major. J Exp Med (1996) 2.03
Functional immunoglobulin M production after transfection of cloned immunoglobulin heavy and light chain genes into lymphoid cells. Proc Natl Acad Sci U S A (1983) 2.03
Human CD1d-glycolipid tetramers generated by in vitro oxidative refolding chromatography. Proc Natl Acad Sci U S A (2001) 1.99
Conformational isomerism and the diversity of antibodies. Proc Natl Acad Sci U S A (1994) 1.99
Monoclonal antibodies as probes for differentiation and tumor-associated antigens: a Forssman specificity on teratocarcinoma stem cells. Cell (1978) 1.97
Original and artificial antibodies. Nature (1992) 1.97
Structure and evolution of immunoglobulins. Prog Biophys Mol Biol (1970) 1.96
The IgM antigen receptor of B lymphocytes is associated with prohibitin and a prohibitin-related protein. EMBO J (1994) 1.94
Discriminating intrinsic and antigen-selected mutational hotspots in immunoglobulin V genes. Immunol Today (1993) 1.93
Negative regulation of airway responsiveness that is dependent on gammadelta T cells and independent of alphabeta T cells. Nat Med (1999) 1.93
Reshaping human antibodies: grafting an antilysozyme activity. Science (1988) 1.92
Three rat monoclonal antibodies to human C3. Immunology (1980) 1.91
Molecular analysis of spontaneous somatic mutants. Nature (1977) 1.90
Defective nitric oxide effector functions lead to extreme susceptibility of Trypanosoma cruzi-infected mice deficient in gamma interferon receptor or inducible nitric oxide synthase. Infect Immun (1998) 1.89
The disulphide bridges of immunoglobulin kappa-chains. Biochem J (1966) 1.89
Nonsense mutations inhibit RNA splicing in a cell-free system: recognition of mutant codon is independent of protein synthesis. Cell (1996) 1.88
Both innate and acquired immunity to Listeria monocytogenes infection are increased in IL-10-deficient mice. J Immunol (1997) 1.87
Low cytoplasmic mRNA levels of immunoglobulin kappa light chain genes containing nonsense codons correlate with inefficient splicing. EMBO J (1994) 1.87
A differentially expressed murine RNA encoding a protein with similarities to two types of nucleic acid binding motifs. Nucleic Acids Res (1991) 1.86
The amino acid sequence around the reactive serine residue in alkaline phosphatase from Escherichia coli. Biochem J (1964) 1.83
Somatic hypermutation of immunoglobulin kappa may depend on sequences 3' of C kappa and occurs on passenger transgenes. EMBO J (1991) 1.83
Letter: Fusion of two immunoglobulin-producing myeloma cells. Nature (1973) 1.83
Regulation of membrane IgM expression in secretory B cells: translational and post-translational events. EMBO J (1987) 1.82
Targeting of non-Ig sequences in place of the V segment by somatic hypermutation. Nature (1995) 1.80
Isolation of CD1 genes: a family of major histocompatibility complex-related differentiation antigens. Proc Natl Acad Sci U S A (1986) 1.77
Impaired macrophage listericidal and cytokine activities are responsible for the rapid death of Listeria monocytogenes-infected IFN-gamma receptor-deficient mice. J Immunol (1997) 1.76
Affinity maturation leads to differential expression of multiple copies of a kappa light-chain transgene. Nature (1993) 1.75
Secretion of immunoglobulin M assembly intermediates in the presence of reducing agents. Nature (1990) 1.74
Impaired mucosal immune responses in interleukin 4-targeted mice. J Exp Med (1995) 1.71
Russell bodies: a general response of secretory cells to synthesis of a mutant immunoglobulin which can neither exit from, nor be degraded in, the endoplasmic reticulum. J Cell Biol (1991) 1.70
Codon bias targets mutation. Nature (1995) 1.69
Switch junction sequences in PMS2-deficient mice reveal a microhomology-mediated mechanism of Ig class switch recombination. Proc Natl Acad Sci U S A (2001) 1.69
Control of HLA-A,B,C synthesis and expression in interferon-treated cells. EMBO J (1982) 1.69
Monoclonal antibodies as tools to analyze the serological and genetic complexities of major transplantation antigens. Immunol Rev (1979) 1.67
Partial deletion in the heavy chain disease protein ZUC. Nature (1969) 1.65
The immune response to Plasmodium chabaudi malaria in interleukin-4-deficient mice. Eur J Immunol (1994) 1.63
Monoclonal antibodies specific for murine IgM I. Characterization of antigenic determinants on the four constant domains of the mu heavy chain. Eur J Immunol (1984) 1.58
Mutations affecting the structure and function of immunoglobulin M. Mol Cell Biol (1982) 1.58
Structure and expression of the human thymocyte antigens CD1a, CD1b, and CD1c. Proc Natl Acad Sci U S A (1987) 1.57