Published in Proc Natl Acad Sci U S A on July 01, 1979
Tissue-specific and differentiation-specific expression of a human K14 keratin gene in transgenic mice. Proc Natl Acad Sci U S A (1989) 3.55
Use of peptide tagging to detect proteins expressed from cloned genes: deletion mapping functional domains of Drosophila hsp 70. EMBO J (1984) 2.78
The expression of mutant epidermal keratin cDNAs transfected in simple epithelial and squamous cell carcinoma lines. J Cell Biol (1987) 2.61
Expression of mutant keratin cDNAs in epithelial cells reveals possible mechanisms for initiation and assembly of intermediate filaments. J Cell Biol (1989) 1.89
Peptidergic transmission in sympathetic ganglia of the frog. J Physiol (1982) 1.86
The TGR5 receptor mediates bile acid-induced itch and analgesia. J Clin Invest (2013) 1.27
Calcitonin gene-related peptide and its binding sites in the human central nervous system and pituitary. Proc Natl Acad Sci U S A (1985) 1.24
Substance P-immunoreactive peripheral branches of sensory neurons innervate guinea pig sympathetic neurons. Proc Natl Acad Sci U S A (1982) 1.20
Increase in retinal vasoactive intestinal polypeptide after eyelid fusion in primates. Proc Natl Acad Sci U S A (1988) 1.16
Intrinsic and extrinsic inhibitory synaptic inputs to submucous neurones of the guinea-pig small intestine. J Physiol (1988) 1.15
Isolation, sequence, and differential expression of a human K7 gene in simple epithelial cells. J Cell Biol (1988) 1.05
Immunohistochemical demonstration of substance P in the lower respiratory tract of the rabbit and not of man. Thorax (1983) 1.04
Protein kinase C mediates the synergistic interaction between agonists acting at alpha2-adrenergic and delta-opioid receptors in spinal cord. J Neurosci (2009) 1.02
Coexpression of alpha 2A-adrenergic and delta-opioid receptors in substance P-containing terminals in rat dorsal horn. J Comp Neurol (2009) 1.02
Advantages of bispecific hybridomas in one-step immunocytochemistry and immunoassays. Proc Natl Acad Sci U S A (1986) 1.01
Projections of chemically identified myenteric neurons of the small and large intestine of the mouse. J Anat (1997) 1.01
On lateral septum-like characteristics of outputs from the accumbal hedonic "hotspot" of Peciña and Berridge with commentary on the transitional nature of basal forebrain "boundaries". J Comp Neurol (2013) 1.00
Developmental abnormalities of neuronal structure and function in prenatal mice lacking the prader-willi syndrome gene necdin. Am J Pathol (2005) 0.94
Differential localization of vesicular glutamate transporters and peptides in corneal afferents to trigeminal nucleus caudalis. J Comp Neurol (2010) 0.94
Upregulation of substance P in low-threshold myelinated afferents is not required for tactile allodynia in the chronic constriction injury and spinal nerve ligation models. J Neurosci (2007) 0.92
GABAergic inputs from direct and indirect striatal projection neurons onto cholinergic interneurons in the primate putamen. J Comp Neurol (2013) 0.91
Some properties and applications of monoclonal antibodies. Biochem J (1981) 0.88
Autonomic mechanisms underlying capsaicin induced oral sensations and salivation in man. J Physiol (1986) 0.87
Distribution and physiological effects of B-type allatostatins (myoinhibitory peptides, MIPs) in the stomatogastric nervous system of the crab Cancer borealis. J Comp Neurol (2011) 0.86
Expression of gastrin-releasing peptide by excitatory interneurons in the mouse superficial dorsal horn. Mol Pain (2014) 0.86
Substance P immunoreactivity exhibits frequent colocalization with kisspeptin and neurokinin B in the human infundibular region. PLoS One (2013) 0.85
A population of large neurons in laminae III and IV of the rat spinal cord that have long dorsal dendrites and lack the neurokinin 1 receptor. Eur J Neurosci (2007) 0.85
Substance P-immunoreactive retinal ganglion cells and their central axon terminals in the rabbit. Nature (1987) 0.84
Neuroantibodies: molecular cloning of a monoclonal antibody against substance P for expression in the central nervous system. Proc Natl Acad Sci U S A (1991) 0.81
A new antigen retrieval technique for human brain tissue. PLoS One (2008) 0.81
Distribution of C-type allatostatin (C-AST)-like immunoreactivity in the central nervous system of the copepod Calanus finmarchicus. Gen Comp Endocrinol (2010) 0.80
Kainate receptors are primarily postsynaptic to SP-containing axon terminals in the trigeminal dorsal horn. Brain Res (2007) 0.79
Immunocytochemistry with internally labeled monoclonal antibodies. Proc Natl Acad Sci U S A (1982) 0.79
Conserved expression of the GPR151 receptor in habenular axonal projections of vertebrates. J Comp Neurol (2014) 0.79
Chemical parcellation of the anterior thalamic nuclei in the human brain. J Neural Transm (Vienna) (2007) 0.79
Substance P-containing neurons of the avian suprachiasmatic nucleus project directly to the nucleus of Edinger-Westphal. Proc Natl Acad Sci U S A (1982) 0.78
Selective innervation of NK1 receptor-lacking lamina I spinoparabrachial neurons by presumed nonpeptidergic Aδ nociceptors in the rat. Pain (2014) 0.78
Tachykinin-immunoreactive neurons in developing feline neostriatum: somatodendritic morphogenesis demonstrated by combined immunohistochemistry/Golgi impregnation-gold toning. Dev Neurosci (2011) 0.77
The Therapeutic Potential of Targeting Substance P/NK-1R Interactions in Inflammatory CNS Disorders. Front Cell Neurosci (2017) 0.77
Comparative analysis of glucagonergic cells, glia, and the circumferential marginal zone in the reptilian retina. J Comp Neurol (2015) 0.77
Substance P in the bovine retina: localization, identification, release, uptake and receptor analysis. J Physiol (1984) 0.76
Functional studies of the carboxy-terminal repeat domain of Drosophila RNA polymerase II in vivo. Genetics (1995) 0.76
Feeding-dependent activation of enteric cells and sensory neurons by lymphatic fluid: evidence for a neurolymphocrine system. Am J Physiol Gastrointest Liver Physiol (2014) 0.76
From the structure of antibodies to the diversification of the immune response. EMBO J (1985) 0.76
Colocalization of cocaine- and amphetamine-regulated transcript with kisspeptin and neurokinin B in the human infundibular region. PLoS One (2014) 0.76
Inflammation-induced abnormalities in the subcellular localization and trafficking of the neurokinin 1 receptor in the enteric nervous system. Am J Physiol Gastrointest Liver Physiol (2015) 0.76
The human cuneate nucleus contains discrete subregions whose neurochemical features match those of the relay nuclei for nociceptive information. Brain Struct Funct (2013) 0.75
Neurochemical compartmentalization within the pigeon basal ganglia. J Chem Neuroanat (2016) 0.75
Anatomical Organization of Multiple Modulatory Inputs in a Rhythmic Motor System. PLoS One (2015) 0.75
Early postnatal administration of 5,7-dihydroxytryptamine: effects on substance P and thyrotropin-releasing hormone neurons and terminals in rat brain. Brain Res (1986) 0.75
Synaptic organization of striate cortex projections in the tree shrew: A comparison of the claustrum and dorsal thalamus. J Comp Neurol (2016) 0.75
Neurokinin-1 receptor immunoreactive neuronal elements in the superficial dorsal horn of the chicken spinal cord: with special reference to their relationship with the tachykinin-containing central axon terminals in synaptic glomeruli. Acta Histochem Cytochem (2009) 0.75
Intrasellar hamartoma associated with pituitary adenoma. Acta Neuropathol (1990) 0.75
Preparation of iodine-131 labelled human growth hormone of high specific activity. Nature (1962) 64.93
Antibodies to major histocompatibility antigens produced by hybrid cell lines. Nature (1977) 16.54
Fusion between immunoglobulin-secreting and nonsecreting myeloma cell lines. Eur J Immunol (1976) 7.64
[Central transmission of afferent impulses. III. Incidence and significance of the substance P in the dorsal roots of the spinal cord]. Naunyn Schmiedebergs Arch Exp Pathol Pharmakol (1953) 3.03
Experimental immunohistochemical studies on the localization and distribution of substance P in cat primary sensory neurons. Brain Res (1975) 2.72
Distribution of substance P-like immunoreactivity in the central nervous system of the rat--I. Cell bodies and nerve terminals. Neuroscience (1978) 1.99
Substance P and excitatory transmitter of primary sensory neurons. Cold Spring Harb Symp Quant Biol (1976) 1.93
Letter: Fusion of two immunoglobulin-producing myeloma cells. Nature (1973) 1.83
Post mortem changes and regional distribution of substance P in the rat and mouse nervous system. Brain Res (1976) 1.82
Immunohistochemical evidence of substance P-like immunoreactivity in some 5-hydroxytryptamine-containing neurons in the rat central nervous system. Neuroscience (1978) 1.67
Serotonin and substance P coexist i, neurons of the rat's central nervous system. Proc Natl Acad Sci U S A (1978) 1.63
The distribution of substance P immunoreactive fibers in the rat central nervous system. J Comp Neurol (1978) 1.63
Radioimmunoassay for substance P. Nat New Biol (1973) 1.41
Ultrastructural localization of substance P in neurons of rat spinal cord. Brain Res (1977) 1.34
Ultrastructural identification of substance P cells and their processes in rat sensory ganglia and their terminals in the spinal cord by immunocytochemistry. Proc Natl Acad Sci U S A (1977) 1.27
Substance P in the vagus nerve. Immunochemical and immunohistochemical evidence for axoplasmic transport. Naunyn Schmiedebergs Arch Pharmacol (1979) 1.23
Regional distribution of substance P in the brain of the rat. Brain Res (1976) 1.23
Monoclonal antibodies and cell surface antigens. Cell Biol Int Rep (1979) 1.06
Substance P: localization in synaptic vesicles in rat central nervous system. J Neurochem (1977) 0.99
Continuous cultures of fused cells secreting antibody of predefined specificity. Nature (1975) 83.56
Derivation of specific antibody-producing tissue culture and tumor lines by cell fusion. Eur J Immunol (1976) 30.70
Antibodies to major histocompatibility antigens produced by hybrid cell lines. Nature (1977) 16.54
Production of monoclonal antibodies to group A erythrocytes, HLA and other human cell surface antigens-new tools for genetic analysis. Cell (1978) 14.82
Preparation of monoclonal antibodies: strategies and procedures. Methods Enzymol (1981) 14.45
A possible precursor of immunoglobulin light chains. Nat New Biol (1972) 11.03
Mac-1: a macrophage differentiation antigen identified by monoclonal antibody. Eur J Immunol (1979) 10.51
Rat monoclonal antitubulin antibodies derived by using a new nonsecreting rat cell line. J Cell Biol (1982) 9.66
Analysis of cell surfaces by xenogeneic myeloma-hybrid antibodies: differentiation antigens of rat lymphocytes. Cell (1977) 8.46
Complete sequence of constant and 3' noncoding regions of an immunoglobulin mRNA using the dideoxynucleotide method of RNA sequencing. Cell (1978) 8.20
Fusion between immunoglobulin-secreting and nonsecreting myeloma cell lines. Eur J Immunol (1976) 7.64
Rat x rat hybrid myelomas and a monoclonal anti-Fd portion of mouse IgG. Nature (1979) 5.69
Monoclonal xenogeneic antibodies to murine cell surface antigens: identification of novel leukocyte differentiation antigens. Eur J Immunol (1978) 5.35
A human thymocyte antigen defined by a hybrid myeloma monoclonal antibody. Eur J Immunol (1979) 5.17
Isolation of a fragment of tau derived from the core of the paired helical filament of Alzheimer disease. Proc Natl Acad Sci U S A (1988) 4.45
Somatic mutation and the maturation of immune response to 2-phenyl oxazolone. Nature (1984) 4.45
Mutation drift and repertoire shift in the maturation of the immune response. Immunol Rev (1987) 4.16
Man-made antibodies. Nature (1991) 3.88
Origin of antibody variation. Nature (1966) 3.50
Kinetic maturation of an immune response. Nature (1991) 3.26
T-lymphocyte heterogeneity in the rat: separation of functional subpopulations using a monoclonal antibody. J Exp Med (1978) 3.20
Hot spot focusing of somatic hypermutation in MSH2-deficient mice suggests two stages of mutational targeting. Immunity (1998) 3.16
Linked groups of residues in immunoglobulin k chains. Nature (1967) 3.12
Elements regulating somatic hypermutation of an immunoglobulin kappa gene: critical role for the intron enhancer/matrix attachment region. Cell (1994) 3.06
The complete amino acid sequence of a mouse kappa light chain. Biochem J (1972) 2.94
Molecular events during maturation of the immune response to oxazolone. Nature (1985) 2.78
mRNA sequences define an unusually restricted IgG response to 2-phenyloxazolone and its early diversification. Nature (1983) 2.72
Structural studies of immunoglobulin G. Nature (1969) 2.63
Variations in the S-S bridges of immunoglobins G: interchain disulfide bridges of gamma G3 myeloma proteins. J Mol Biol (1968) 2.57
An immunoglobulin deletion mutant with implications for the heavy-chain switch and RNA splicing. Nature (1980) 2.41
Passenger transgenes reveal intrinsic specificity of the antibody hypermutation mechanism: clustering, polarity, and specific hot spots. Proc Natl Acad Sci U S A (1993) 2.30
Hybrid hybridomas and their use in immunohistochemistry. Nature (1983) 2.24
Sequence analysis of immunoglobulin light chain messenger RNA. Nature (1974) 2.22
A novel family of human major histocompatibility complex-related genes not mapping to chromosome 6. Nature (1986) 2.22
Complete sequence of an immunoglobulin mRNA using specific priming and the dideoxynucleotide method of RNA sequencing. Nucleic Acids Res (1981) 2.16
Variations in amino-acid sequence near the disulphide bridges of Bence-Jones proteins. Nature (1966) 2.14
Intracellular immunoglobulin chain synthesis in non-secreting variants of a mouse myeloma: detection of inactive light-chain messenger RNA. J Mol Biol (1974) 2.14
Developmental regulation of IgM secretion: the role of the carboxy-terminal cysteine. Cell (1990) 2.12
Human immunoglobulin subclasses. Partial amino acid sequence of the constant region of a gamma 4 chain. Biochem J (1970) 2.11
Two classes of CD1 genes. Eur J Immunol (1989) 2.11
Structure and biological properties of immunoglobulins. Adv Immunol (1967) 2.08
The dynamic nature of the antibody repertoire. Immunol Rev (1988) 2.08
Somatic hypermutation. Curr Opin Immunol (1995) 2.08
Human CD1d-glycolipid tetramers generated by in vitro oxidative refolding chromatography. Proc Natl Acad Sci U S A (2001) 1.99
Conformational isomerism and the diversity of antibodies. Proc Natl Acad Sci U S A (1994) 1.99
Monoclonal antibodies as probes for differentiation and tumor-associated antigens: a Forssman specificity on teratocarcinoma stem cells. Cell (1978) 1.97
Original and artificial antibodies. Nature (1992) 1.97
Structure and evolution of immunoglobulins. Prog Biophys Mol Biol (1970) 1.96
Release of dopamine from dendrites in rat substantia nigra. Nature (1976) 1.95
Discriminating intrinsic and antigen-selected mutational hotspots in immunoglobulin V genes. Immunol Today (1993) 1.93
Reshaping human antibodies: grafting an antilysozyme activity. Science (1988) 1.92
Three rat monoclonal antibodies to human C3. Immunology (1980) 1.91
Molecular analysis of spontaneous somatic mutants. Nature (1977) 1.90
The disulphide bridges of immunoglobulin kappa-chains. Biochem J (1966) 1.89
Nonsense mutations inhibit RNA splicing in a cell-free system: recognition of mutant codon is independent of protein synthesis. Cell (1996) 1.88
Low cytoplasmic mRNA levels of immunoglobulin kappa light chain genes containing nonsense codons correlate with inefficient splicing. EMBO J (1994) 1.87
The amino acid sequence around the reactive serine residue in alkaline phosphatase from Escherichia coli. Biochem J (1964) 1.83
Letter: Fusion of two immunoglobulin-producing myeloma cells. Nature (1973) 1.83
Somatic hypermutation of immunoglobulin kappa may depend on sequences 3' of C kappa and occurs on passenger transgenes. EMBO J (1991) 1.83
Regulation of membrane IgM expression in secretory B cells: translational and post-translational events. EMBO J (1987) 1.82
Use of catechol O-methyltransferase for the enzyme radiochemical assay of dopamine. J Neurochem (1973) 1.82
Continuous cultures of fused cells secreting antibody of predefined specificity. 1975. J Immunol (2005) 1.80
Capsaicin-induced depletion of substance P from primary sensory neurones. Brain Res (1978) 1.80
Targeting of non-Ig sequences in place of the V segment by somatic hypermutation. Nature (1995) 1.80
Isolation of CD1 genes: a family of major histocompatibility complex-related differentiation antigens. Proc Natl Acad Sci U S A (1986) 1.77
Affinity maturation leads to differential expression of multiple copies of a kappa light-chain transgene. Nature (1993) 1.75
Secretion of immunoglobulin M assembly intermediates in the presence of reducing agents. Nature (1990) 1.74
Russell bodies: a general response of secretory cells to synthesis of a mutant immunoglobulin which can neither exit from, nor be degraded in, the endoplasmic reticulum. J Cell Biol (1991) 1.70
Codon bias targets mutation. Nature (1995) 1.69
Switch junction sequences in PMS2-deficient mice reveal a microhomology-mediated mechanism of Ig class switch recombination. Proc Natl Acad Sci U S A (2001) 1.69
Control of HLA-A,B,C synthesis and expression in interferon-treated cells. EMBO J (1982) 1.69
Monoclonal antibodies as tools to analyze the serological and genetic complexities of major transplantation antigens. Immunol Rev (1979) 1.67
Use of different hapten-protein conjugates immobilized on nitrocellulose to screen monoclonal antibodies to abscisic acid. Anal Biochem (1985) 1.66
Partial deletion in the heavy chain disease protein ZUC. Nature (1969) 1.65
The distribution of substance P immunoreactive fibers in the rat central nervous system. J Comp Neurol (1978) 1.63
Structure and expression of the human thymocyte antigens CD1a, CD1b, and CD1c. Proc Natl Acad Sci U S A (1987) 1.57
Activation of memory and virgin B cell clones in hyperimmune animals. Eur J Immunol (1987) 1.54
Monoclonal antibodies to antigens in the peribacteroid membrane from Rhizobium-induced root nodules of pea cross-react with plasma membranes and Golgi bodies. EMBO J (1985) 1.53
Anti-oxazolone hybridomas and the structure of the oxazolone idiotype. J Immunol (1983) 1.52
The central and peripheral ends of the substance P-containing sensory neurones in the rat trigeminal system. Brain Res (1978) 1.52
Monitoring and interpreting the intrinsic features of somatic hypermutation. Immunol Rev (1998) 1.51
Sequence and evolution of the human T-cell antigen receptor beta-chain genes. Proc Natl Acad Sci U S A (1985) 1.50
Subpopulations of normal and leukemic human thymocytes: an analysis with the use of monoclonal antibodies. J Natl Cancer Inst (1980) 1.50
A small polypeptide different from beta2-microglobin associated with a human cell surface antigen. Nature (1979) 1.49
Translation of messenger RNA for immunoglobulin light chains in a cell-free system from Krebs II ascites cells. FEBS Lett (1972) 1.49
Early changes in neurons of the hippocampus and neocortex in transgenic rats expressing intracellular human a-beta. J Alzheimers Dis (2004) 1.48
Purification and sequence of messenger RNA for immunoglobulin light chains. Nat New Biol (1973) 1.46
Cells strongly expressing Ig(kappa) transgenes show clonal recruitment of hypermutation: a role for both MAR and the enhancers. EMBO J (1997) 1.46
Analysis of somatic hypermutation in mouse Peyer's patches using immunoglobulin kappa light-chain transgenes. Proc Natl Acad Sci U S A (1993) 1.46
Disulphide bridges of immunoglobin G-1 heavy chains. Nature (1967) 1.44
Recovery of the genome of murine sarcoma virus (MSV) after infection of cells with nuclear DNA from MSV transformed non-virus producing cells. Eur J Cancer (1973) 1.44
Coexistence of galanin-like immunoreactivity with catecholamines, 5-hydroxytryptamine, GABA and neuropeptides in the rat CNS. J Neurosci (1986) 1.43
Expression of spleen cell immunoglobulin phenotype in hybrids with myeloma cell lines. Somatic Cell Genet (1981) 1.42
Mouse CD1 is distinct from and co-exists with TL in the same thymus. EMBO J (1988) 1.41
Difference between the tau protein of Alzheimer paired helical filament core and normal tau revealed by epitope analysis of monoclonal antibodies 423 and 7.51. Proc Natl Acad Sci U S A (1991) 1.41