Published in J Am Soc Nephrol on February 23, 2005
A "holistic" kinesin phylogeny reveals new kinesin families and predicts protein functions. Mol Biol Cell (2006) 1.59
Autosomal recessive polycystic kidney disease and congenital hepatic fibrosis: summary statement of a first National Institutes of Health/Office of Rare Diseases conference. J Pediatr (2006) 1.26
Validation of endogenous internal real-time PCR controls in renal tissues. Am J Nephrol (2009) 1.03
HNF-1beta regulates transcription of the PKD modifier gene Kif12. J Am Soc Nephrol (2008) 1.03
Renal CD14 expression correlates with the progression of cystic kidney disease. Kidney Int (2010) 0.98
The Future of Polycystic Kidney Disease Research--As Seen By the 12 Kaplan Awardees. J Am Soc Nephrol (2015) 0.93
Acceleration of polycystic kidney disease progression in cpk mice carrying a deletion in the homeodomain protein Cux1. Am J Physiol Renal Physiol (2008) 0.91
Receptor protein tyrosine phosphatases are novel components of a polycystin complex. Biochim Biophys Acta (2010) 0.87
Hnf1b controls pancreas morphogenesis and the generation of Ngn3+ endocrine progenitors. Development (2015) 0.86
Maternal environment interacts with modifier genes to influence progression of nephrotic syndrome. J Am Soc Nephrol (2008) 0.85
Kidney injury accelerates cystogenesis via pathways modulated by heme oxygenase and complement. J Am Soc Nephrol (2012) 0.84
Role of genetic modifiers in an orthologous rat model of ARPKD. Physiol Genomics (2012) 0.83
Copy number variation analysis identifies novel CAKUT candidate genes in children with a solitary functioning kidney. Kidney Int (2015) 0.82
EYA1 and SIX1 gene mutations in Japanese patients with branchio-oto-renal (BOR) syndrome and related conditions. Pediatr Nephrol (2006) 0.81
Clinical and genetic characterization of a founder PKHD1 mutation in Afrikaners with ARPKD. Pediatr Nephrol (2014) 0.78
Genetic loci that affect aristolochic acid-induced nephrotoxicity in the mouse. Am J Physiol Renal Physiol (2011) 0.77
Genetic contribution and associated pathophysiology in end-stage renal disease. Appl Clin Genet (2010) 0.77
Inhibition of Comt with tolcapone slows progression of polycystic kidney disease in the more severely affected PKD/Mhm (cy/+) substrain of the Hannover Sprague-Dawley rat. Nephrol Dial Transplant (2013) 0.76
Murine Models of Polycystic Kidney Disease. Drug Discov Today Dis Mech (2013) 0.76
Genetic and Informatic Analyses Implicate Kif12 as a Candidate Gene within the Mpkd2 Locus That Modulates Renal Cystic Disease Severity in the Cys1cpk Mouse. PLoS One (2015) 0.75
Magnetic resonance microscopy of renal and biliary abnormalities in excised tissues from a mouse model of autosomal recessive polycystic kidney disease. Physiol Rep (2015) 0.75
High-resolution genetic localization of a modifying locus affecting disease severity in the juvenile cystic kidneys (jck) mouse model of polycystic kidney disease. Mamm Genome (2016) 0.75
Transforming growth factor-beta induces development of the T(H)17 lineage. Nature (2006) 25.91
R/qtl: QTL mapping in experimental crosses. Bioinformatics (2003) 22.38
Microarray data analysis: from disarray to consolidation and consensus. Nat Rev Genet (2006) 16.12
Identification of functional elements and regulatory circuits by Drosophila modENCODE. Science (2010) 12.39
The developmental transcriptome of Drosophila melanogaster. Nature (2010) 11.85
Identification of conserved gene expression features between murine mammary carcinoma models and human breast tumors. Genome Biol (2007) 10.49
Characterization of human embryonic stem cell lines by the International Stem Cell Initiative. Nat Biotechnol (2007) 9.36
Repeatability of published microarray gene expression analyses. Nat Genet (2008) 8.24
Statistical tests for differential expression in cDNA microarray experiments. Genome Biol (2003) 7.65
Variation in gene expression within and among natural populations. Nat Genet (2002) 7.19
Volume progression in polycystic kidney disease. N Engl J Med (2006) 7.16
Comparative genomics identifies a flagellar and basal body proteome that includes the BBS5 human disease gene. Cell (2004) 6.10
The polycystic kidney disease proteins, polycystin-1, polycystin-2, polaris, and cystin, are co-localized in renal cilia. J Am Soc Nephrol (2002) 5.58
Improved statistical tests for differential gene expression by shrinking variance components estimates. Biostatistics (2005) 5.57
Renal structure in early autosomal-dominant polycystic kidney disease (ADPKD): The Consortium for Radiologic Imaging Studies of Polycystic Kidney Disease (CRISP) cohort. Kidney Int (2003) 4.84
On the subspecific origin of the laboratory mouse. Nat Genet (2007) 4.68
Candidate exome capture identifies mutation of SDCCAG8 as the cause of a retinal-renal ciliopathy. Nat Genet (2010) 3.99
The nature and identification of quantitative trait loci: a community's view. Nat Rev Genet (2003) 3.96
Monoclonal anti-interleukin 23 reverses active colitis in a T cell-mediated model in mice. Gastroenterology (2007) 3.82
Subspecific origin and haplotype diversity in the laboratory mouse. Nat Genet (2011) 3.64
Synthetic spike-in standards for RNA-seq experiments. Genome Res (2011) 3.58
The mouse as a model for human biology: a resource guide for complex trait analysis. Nat Rev Genet (2007) 3.55
A customized and versatile high-density genotyping array for the mouse. Nat Methods (2009) 3.53
The Collaborative Cross at Oak Ridge National Laboratory: developing a powerful resource for systems genetics. Mamm Genome (2008) 3.52
High-resolution genetic mapping using the Mouse Diversity outbred population. Genetics (2012) 3.28
Comprehensive molecular diagnostics in autosomal dominant polycystic kidney disease. J Am Soc Nephrol (2007) 3.26
Genetic analysis of complex traits in the emerging Collaborative Cross. Genome Res (2011) 3.25
PKHD1, the polycystic kidney and hepatic disease 1 gene, encodes a novel large protein containing multiple immunoglobulin-like plexin-transcription-factor domains and parallel beta-helix 1 repeats. Am J Hum Genet (2002) 3.21
Aging in inbred strains of mice: study design and interim report on median lifespans and circulating IGF1 levels. Aging Cell (2009) 3.16
Bayesian model selection for genome-wide epistatic quantitative trait loci analysis. Genetics (2005) 3.10
Th22 cells are an important source of IL-22 for host protection against enteropathogenic bacteria. Immunity (2012) 2.87
A new standard genetic map for the laboratory mouse. Genetics (2009) 2.78
A dominant, coordinated T regulatory cell-IgA response to the intestinal microbiota. Proc Natl Acad Sci U S A (2009) 2.77
Requisite role for the dectin-1 beta-glucan receptor in pulmonary defense against Aspergillus fumigatus. J Immunol (2009) 2.74
Evidence of a large-scale functional organization of mammalian chromosomes. PLoS Genet (2005) 2.73
Multiple trait measurements in 43 inbred mouse strains capture the phenotypic diversity characteristic of human populations. J Appl Physiol (1985) (2007) 2.70
An imputed genotype resource for the laboratory mouse. Mamm Genome (2008) 2.54
Structural model analysis of multiple quantitative traits. PLoS Genet (2006) 2.45
Crossover interference in the mouse. Genetics (2002) 2.40
Magnetic resonance imaging evaluation of hepatic cysts in early autosomal-dominant polycystic kidney disease: the Consortium for Radiologic Imaging Studies of Polycystic Kidney Disease cohort. Clin J Am Soc Nephrol (2005) 2.37
Design and validation issues in RNA-seq experiments. Brief Bioinform (2011) 2.26
Transformations for cDNA microarray data. Stat Appl Genet Mol Biol (2003) 2.23
Cyst number but not the rate of cystic growth is associated with the mutated gene in autosomal dominant polycystic kidney disease. J Am Soc Nephrol (2006) 2.21
Cystin, a novel cilia-associated protein, is disrupted in the cpk mouse model of polycystic kidney disease. J Clin Invest (2002) 2.07
Medium-chain acyl-CoA dehydrogenase deficiency in gene-targeted mice. PLoS Genet (2005) 2.03
Polycistronic lentiviral vector for "hit and run" reprogramming of adult skin fibroblasts to induced pluripotent stem cells. Stem Cells (2009) 2.01
Effects of atherogenic diet on hepatic gene expression across mouse strains. Physiol Genomics (2009) 2.00
Sex- and lineage-specific inheritance of depression-like behavior in the rat. Mamm Genome (2004) 1.99
Macromolecule biosynthesis: a key function of sleep. Physiol Genomics (2007) 1.93
Microbiota innate stimulation is a prerequisite for T cell spontaneous proliferation and induction of experimental colitis. J Exp Med (2010) 1.86
A classification of ductal plate malformations based on distinct pathogenic mechanisms of biliary dysmorphogenesis. Hepatology (2011) 1.84
A collaborative database of inbred mouse strain characteristics. Bioinformatics (2004) 1.79
Cystin localizes to primary cilia via membrane microdomains and a targeting motif. J Am Soc Nephrol (2009) 1.79
Heightened epithelial Na+ channel-mediated Na+ absorption in a murine polycystic kidney disease model epithelium lacking apical monocilia. Am J Physiol Cell Physiol (2005) 1.74
Quantitative trait locus analysis for obesity reveals multiple networks of interacting loci. Mamm Genome (2006) 1.74
Genetic analysis in the Collaborative Cross breeding population. Genome Res (2011) 1.74
Using advanced intercross lines for high-resolution mapping of HDL cholesterol quantitative trait loci. Genome Res (2003) 1.66
Inactivation of Smad4 accelerates Kras(G12D)-mediated pancreatic neoplasia. Cancer Res (2007) 1.66
The X chromosome in quantitative trait locus mapping. Genetics (2006) 1.65
Combining data from multiple inbred line crosses improves the power and resolution of quantitative trait loci mapping. Genetics (2005) 1.58
Characterization of large rearrangements in autosomal dominant polycystic kidney disease and the PKD1/TSC2 contiguous gene syndrome. Kidney Int (2008) 1.58
Mitigation of chlorine-induced lung injury by low-molecular-weight antioxidants. Am J Physiol Lung Cell Mol Physiol (2008) 1.58
Quantitative trait loci analysis for plasma HDL-cholesterol concentrations and atherosclerosis susceptibility between inbred mouse strains C57BL/6J and 129S1/SvImJ. Arterioscler Thromb Vasc Biol (2003) 1.58
Intragenic motifs regulate the transcriptional complexity of Pkhd1/PKHD1. J Mol Med (Berl) (2014) 1.56
Statistical design and the analysis of gene expression microarray data. Genet Res (2007) 1.56
Magnetic resonance measurements of renal blood flow and disease progression in autosomal dominant polycystic kidney disease. Clin J Am Soc Nephrol (2006) 1.53
Mapping quantitative trait loci for vertebral trabecular bone volume fraction and microarchitecture in mice. J Bone Miner Res (2003) 1.52
PPARgamma2 nuclear receptor controls multiple regulatory pathways of osteoblast differentiation from marrow mesenchymal stem cells. J Cell Biochem (2009) 1.51
PPARG by dietary fat interaction influences bone mass in mice and humans. J Bone Miner Res (2008) 1.50
Ten years of the collaborative cross. G3 (Bethesda) (2012) 1.50
Sonographic assessment of the severity and progression of autosomal dominant polycystic kidney disease: the Consortium of Renal Imaging Studies in Polycystic Kidney Disease (CRISP). Am J Kidney Dis (2005) 1.49
Loss of primary cilia results in deregulated and unabated apical calcium entry in ARPKD collecting duct cells. Am J Physiol Renal Physiol (2006) 1.47
Magnetic resonance measurements of renal blood flow as a marker of disease severity in autosomal-dominant polycystic kidney disease. Kidney Int (2003) 1.45
The effect of insulin on expression of genes and biochemical pathways in human skeletal muscle. Endocrine (2007) 1.44
Polyductin undergoes notch-like processing and regulated release from primary cilia. Hum Mol Genet (2007) 1.44
Genetic interaction studies link autosomal dominant and recessive polycystic kidney disease in a common pathway. Hum Mol Genet (2007) 1.43
Modeling host genetic regulation of influenza pathogenesis in the collaborative cross. PLoS Pathog (2013) 1.43
Polyductin, the PKHD1 gene product, comprises isoforms expressed in plasma membrane, primary cilium, and cytoplasm. Kidney Int (2004) 1.42
Imputation of single-nucleotide polymorphisms in inbred mice using local phylogeny. Genetics (2012) 1.42
Influence of sex and diet on quantitative trait loci for HDL cholesterol levels in an SM/J by NZB/BlNJ intercross population. J Lipid Res (2004) 1.41
Discovery of novel variants in genotyping arrays improves genotype retention and reduces ascertainment bias. BMC Genomics (2012) 1.39
Adult-onset Alopecia areata is a complex polygenic trait in the C3H/HeJ mouse model. J Invest Dermatol (2004) 1.38
Comparison of methods for determining renal function decline in early autosomal dominant polycystic kidney disease: the consortium of radiologic imaging studies of polycystic kidney disease cohort. J Am Soc Nephrol (2006) 1.37
The Oak Ridge Polycystic Kidney mouse: modeling ciliopathies of mice and men. Dev Dyn (2008) 1.36
Positional cloning of jcpk/bpk locus of the mouse. Mamm Genome (2003) 1.35
Genetics of colitis susceptibility in IL-10-deficient mice: backcross versus F2 results contrasted by principal component analysis. Genomics (2002) 1.35
Genetic analysis of hematological parameters in incipient lines of the collaborative cross. G3 (Bethesda) (2012) 1.35
Selective phenotyping for increased efficiency in genetic mapping studies. Genetics (2004) 1.34
Genetic analysis of blood pressure in 8 mouse intercross populations. Hypertension (2009) 1.33
Intercellular adhesion molecule-1 expression is required on multiple cell types for the development of experimental autoimmune encephalomyelitis. J Immunol (2007) 1.31
FXR and ABCG5/ABCG8 as determinants of cholesterol gallstone formation from quantitative trait locus mapping in mice. Gastroenterology (2003) 1.29
The collaborative cross: a recombinant inbred mouse population for the systems genetic era. ILAR J (2011) 1.28
Quantitative trait loci that determine plasma lipids and obesity in C57BL/6J and 129S1/SvImJ inbred mice. J Lipid Res (2004) 1.28