Published in Am Nat on February 03, 2005
Single-cell analysis uncovers extensive biological noise in poliovirus replication. J Virol (2014) 1.02
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Observing micro-evolutionary processes of viral populations at multiple scales. Philos Trans R Soc Lond B Biol Sci (2013) 0.92
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Lineage relationship and protective immunity of memory CD8 T cell subsets. Nat Immunol (2003) 15.51
Bcl6 and Blimp-1 are reciprocal and antagonistic regulators of T follicular helper cell differentiation. Science (2009) 9.22
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ICOS receptor instructs T follicular helper cell versus effector cell differentiation via induction of the transcriptional repressor Bcl6. Immunity (2011) 5.59
Estimating the precursor frequency of naive antigen-specific CD8 T cells. J Exp Med (2002) 5.16
Emerging pathogens: the epidemiology and evolution of species jumps. Trends Ecol Evol (2005) 5.06
Resolution of a chronic viral infection after interleukin-10 receptor blockade. J Exp Med (2006) 4.97
Human circulating PD-1+CXCR3-CXCR5+ memory Tfh cells are highly functional and correlate with broadly neutralizing HIV antibody responses. Immunity (2013) 3.72
Profiling the humoral immune response to infection by using proteome microarrays: high-throughput vaccine and diagnostic antigen discovery. Proc Natl Acad Sci U S A (2005) 3.59
Sequential Monte Carlo without likelihoods. Proc Natl Acad Sci U S A (2007) 3.42
STAT5 is a potent negative regulator of TFH cell differentiation. J Exp Med (2012) 3.37
A Blueprint for HIV Vaccine Discovery. Cell Host Microbe (2012) 3.27
IL-21 and IL-6 are critical for different aspects of B cell immunity and redundantly induce optimal follicular helper CD4 T cell (Tfh) differentiation. PLoS One (2011) 2.92
Germinal center T follicular helper cell IL-4 production is dependent on signaling lymphocytic activation molecule receptor (CD150). J Immunol (2010) 2.85
In vivo regulation of Bcl6 and T follicular helper cell development. J Immunol (2010) 2.63
Immunity and immunological memory following smallpox vaccination. Immunol Rev (2006) 2.57
Memory CD8 T-cell compartment grows in size with immunological experience. Nature (2008) 2.49
Selective CD4+ T cell help for antibody responses to a large viral pathogen: deterministic linkage of specificities. Immunity (2008) 2.43
Norovirus recombination in ORF1/ORF2 overlap. Emerg Infect Dis (2005) 2.41
Bcl6 and Maf cooperate to instruct human follicular helper CD4 T cell differentiation. J Immunol (2012) 2.34
Inadequate T follicular cell help impairs B cell immunity during HIV infection. Nat Med (2013) 2.29
Immune responses to Bacillus anthracis protective antigen in patients with bioterrorism-related cutaneous or inhalation anthrax. J Infect Dis (2004) 2.29
Norovirus recombination. J Gen Virol (2007) 2.22
The receptor Ly108 functions as a SAP adaptor-dependent on-off switch for T cell help to B cells and NKT cell development. Immunity (2012) 2.19
Vaccinia virus H3L envelope protein is a major target of neutralizing antibodies in humans and elicits protection against lethal challenge in mice. J Virol (2005) 2.18
Mutation rates of spoligotypes and variable numbers of tandem repeat loci in Mycobacterium tuberculosis. Infect Genet Evol (2010) 2.15
Proteome-wide analysis of the serological response to vaccinia and smallpox. Proteomics (2007) 2.10
Recombination within the pandemic norovirus GII.4 lineage. J Virol (2013) 1.93
SAP regulates T cell-mediated help for humoral immunity by a mechanism distinct from cytokine regulation. J Exp Med (2006) 1.92
Quantifying the development of the peripheral naive CD4+ T-cell pool in humans. Blood (2009) 1.79
Redundancy and plasticity of neutralizing antibody responses are cornerstone attributes of the human immune response to the smallpox vaccine. J Virol (2008) 1.77
Bcl6 expressing follicular helper CD4 T cells are fate committed early and have the capacity to form memory. J Immunol (2013) 1.71
The epidemiological fitness cost of drug resistance in Mycobacterium tuberculosis. Proc Natl Acad Sci U S A (2009) 1.71
Heavily isotype-dependent protective activities of human antibodies against vaccinia virus extracellular virion antigen B5. J Virol (2009) 1.69
SAP regulation of follicular helper CD4 T cell development and humoral immunity is independent of SLAM and Fyn kinase. J Immunol (2007) 1.68
What is the best control strategy for multiple infectious disease outbreaks? Proc Biol Sci (2007) 1.68
Vaccinia virus-specific CD4+ T cell responses target a set of antigens largely distinct from those targeted by CD8+ T cell responses. J Immunol (2007) 1.66
Neuraminidase inhibitor resistance in influenza: assessing the danger of its generation and spread. PLoS Comput Biol (2007) 1.64
The role of compensatory mutations in the emergence of drug resistance. PLoS Comput Biol (2006) 1.63
Cutting edge: STAT1 is required for IL-6-mediated Bcl6 induction for early follicular helper cell differentiation. J Immunol (2013) 1.57
Vaccinia virus extracellular enveloped virion neutralization in vitro and protection in vivo depend on complement. J Virol (2008) 1.49
Quantitative PCR technique for detecting lymphocytic choriomeningitis virus in vivo. J Virol Methods (2007) 1.45
Within-host population dynamics and the evolution of microparasites in a heterogeneous host population. Evolution (2002) 1.44
Inhibition of NK cell activity by IL-17 allows vaccinia virus to induce severe skin lesions in a mouse model of eczema vaccinatum. J Exp Med (2009) 1.41
Towards a quantitative understanding of the within-host dynamics of influenza A infections. J R Soc Interface (2009) 1.40
Harnessing CD4⁺ T cell responses in HIV vaccine development. Nat Med (2013) 1.39
Quantifying cell turnover using CFSE data. J Immunol Methods (2005) 1.38
Ly9 (CD229)-deficient mice exhibit T cell defects yet do not share several phenotypic characteristics associated with SLAM- and SAP-deficient mice. J Immunol (2006) 1.36
How do pathogen evolution and host heterogeneity interact in disease emergence? Proc Biol Sci (2006) 1.36
NKT cells prevent chronic joint inflammation after infection with Borrelia burgdorferi. Proc Natl Acad Sci U S A (2008) 1.35
spolTools: online utilities for analyzing spoligotypes of the Mycobacterium tuberculosis complex. Bioinformatics (2008) 1.35
Estimation of the rate of killing by cytotoxic T lymphocytes in vivo. Proc Natl Acad Sci U S A (2007) 1.33
OX40 drives protective vaccinia virus-specific CD8 T cells. J Immunol (2008) 1.33
Roles of target cells and virus-specific cellular immunity in primary simian immunodeficiency virus infection. J Virol (2004) 1.29
Estimating change rates of genetic markers using serial samples: applications to the transposon IS6110 in Mycobacterium tuberculosis. Theor Popul Biol (2003) 1.26
The inference of phased haplotypes for the immunoglobulin H chain V region gene loci by analysis of VDJ gene rearrangements. J Immunol (2011) 1.23
Monkeypox-induced immunity and failure of childhood smallpox vaccination to provide complete protection. Clin Vaccine Immunol (2007) 1.20
Dynamic regulation of Bcl6 in follicular helper CD4 T (Tfh) cells. Curr Opin Immunol (2013) 1.16
Mathematical models of cytotoxic T-lymphocyte killing. Immunol Cell Biol (2007) 1.14
Models of deletion for visualizing bacterial variation: an application to tuberculosis spoligotypes. BMC Bioinformatics (2008) 1.14
Peripheral selection rather than thymic involution explains sudden contraction in naive CD4 T-cell diversity with age. Proc Natl Acad Sci U S A (2012) 1.11
B cell-specific expression of B7-2 is required for follicular Th cell function in response to vaccinia virus. J Immunol (2011) 1.10
Method for assessing the similarity between subsets of the T cell receptor repertoire. J Immunol Methods (2007) 1.09
Revisiting estimates of CTL killing rates in vivo. PLoS One (2007) 1.09
Understanding the slow depletion of memory CD4+ T cells in HIV infection. PLoS Med (2007) 1.08
Mathematical models of RNA silencing: unidirectional amplification limits accidental self-directed reactions. Proc Natl Acad Sci U S A (2003) 1.08
The rescaling method for quantifying the turnover of cell populations. J Theor Biol (2003) 1.07
Uncovering the interplay between CD8, CD4 and antibody responses to complex pathogens. Future Microbiol (2010) 1.07
Trade-offs and the evolution of virulence of microparasites: do details matter? Theor Popul Biol (2003) 1.06
OX40 facilitates control of a persistent virus infection. PLoS Pathog (2012) 1.05
Impact of homoplasy on variable numbers of tandem repeats and spoligotypes in Mycobacterium tuberculosis. Infect Genet Evol (2011) 1.04
Antiviral resistance and the control of pandemic influenza: the roles of stochasticity, evolution and model details. J Theor Biol (2008) 1.03
Combination therapy of vaccinia virus infection with human anti-H3 and anti-B5 monoclonal antibodies in a small animal model. Antivir Ther (2010) 1.02
Chronic lymphocytic choriomeningitis virus infection actively down-regulates CD4+ T cell responses directed against a broad range of epitopes. J Immunol (2007) 1.00
Conditions for the evolution of gene clusters in bacterial genomes. PLoS Comput Biol (2010) 0.98
The smallpox vaccine induces an early neutralizing IgM response. Vaccine (2009) 0.97
Effect of human leukocyte antigen heterozygosity on infectious disease outcome: the need for allele-specific measures. BMC Med Genet (2003) 0.97
How do adaptive immune systems control pathogens while avoiding autoimmunity? Trends Ecol Evol (2005) 0.92
Interpreting genotype cluster sizes of Mycobacterium tuberculosis isolates typed with IS6110 and spoligotyping. Infect Genet Evol (2008) 0.92
An epitope conserved in orthopoxvirus A13 envelope protein is the target of neutralizing and protective antibodies. Virology (2011) 0.91
On the control of acute rodent malaria infections by innate immunity. PLoS One (2010) 0.91
The global spread of drug-resistant influenza. J R Soc Interface (2011) 0.90
Imperfect vaccines and the evolution of pathogens causing acute infections in vertebrates. Evolution (2006) 0.89
Modulation of SAP dependent T:B cell interactions as a strategy to improve vaccination. Curr Opin Virol (2013) 0.89
Group-theoretic models of the inversion process in bacterial genomes. J Math Biol (2013) 0.88
A model-based Bayesian estimation of the rate of evolution of VNTR loci in Mycobacterium tuberculosis. PLoS Comput Biol (2012) 0.88
Exact vs. approximate computation: reconciling different estimates of Mycobacterium tuberculosis epidemiological parameters. Genetics (2014) 0.88
Vaccination alters the balance between protective immunity, exhaustion, escape, and death in chronic infections. J Virol (2011) 0.87
Viral mutation rates: modelling the roles of within-host viral dynamics and the trade-off between replication fidelity and speed. Proc Biol Sci (2012) 0.87
Population structure and evolution of pathogenicity of Yersinia pseudotuberculosis. Appl Environ Microbiol (2010) 0.85
Gap junction-mediated antigen transport in immune responses. Trends Immunol (2007) 0.85
How do antigenically varying pathogens avoid cross-reactive responses to invariant antigens? Proc Biol Sci (2012) 0.85
A simple mathematical model helps to explain the immunodominance of CD8 T cells in influenza A virus infections. J Virol (2008) 0.85
Intervention strategies for an influenza pandemic taking into account secondary bacterial infections. Epidemics (2009) 0.85
Exogenous OX40 stimulation during lymphocytic choriomeningitis virus infection impairs follicular Th cell differentiation and diverts CD4 T cells into the effector lineage by upregulating Blimp-1. J Immunol (2013) 0.84
Sharing the burden: antigen transport and firebreaks in immune responses. J R Soc Interface (2008) 0.84
Structural and biochemical characterization of the vaccinia virus envelope protein D8 and its recognition by the antibody LA5. J Virol (2012) 0.84
A population biological approach to understanding the maintenance and loss of the T-cell repertoire during aging. Immunology (2014) 0.83