Published in J Immunol on March 16, 2012
Molecular mechanisms of T cell co-stimulation and co-inhibition. Nat Rev Immunol (2013) 4.72
Human circulating PD-1+CXCR3-CXCR5+ memory Tfh cells are highly functional and correlate with broadly neutralizing HIV antibody responses. Immunity (2013) 3.72
T follicular helper cell differentiation, function, and roles in disease. Immunity (2014) 3.29
The origins, function, and regulation of T follicular helper cells. J Exp Med (2012) 2.59
Expansion of HIV-specific T follicular helper cells in chronic HIV infection. J Clin Invest (2012) 2.55
Follicular helper T cells serve as the major CD4 T cell compartment for HIV-1 infection, replication, and production. J Exp Med (2012) 2.46
The good, the bad and the ugly - TFH cells in human health and disease. Nat Rev Immunol (2013) 2.33
Inadequate T follicular cell help impairs B cell immunity during HIV infection. Nat Med (2013) 2.29
The receptor Ly108 functions as a SAP adaptor-dependent on-off switch for T cell help to B cells and NKT cell development. Immunity (2012) 2.19
IFN-γ and IL-21 Double Producing T Cells Are Bcl6-Independent and Survive into the Memory Phase in Plasmodium chabaudi Infection. PLoS One (2015) 2.09
A LncRNA-MAF:MAFB transcription factor network regulates epidermal differentiation. Dev Cell (2015) 1.76
Bcl6 expressing follicular helper CD4 T cells are fate committed early and have the capacity to form memory. J Immunol (2013) 1.71
Cutting edge: STAT1 is required for IL-6-mediated Bcl6 induction for early follicular helper cell differentiation. J Immunol (2013) 1.57
Dynamic signaling by T follicular helper cells during germinal center B cell selection. Science (2014) 1.51
Specificity through cooperation: BATF-IRF interactions control immune-regulatory networks. Nat Rev Immunol (2013) 1.50
Pathologically expanded peripheral T helper cell subset drives B cells in rheumatoid arthritis. Nature (2017) 1.50
Activin A programs the differentiation of human TFH cells. Nat Immunol (2016) 1.45
BAFF regulates follicular helper t cells and affects their accumulation and interferon-γ production in autoimmunity. Arthritis Rheumatol (2015) 1.45
Early Loss of Splenic Tfh Cells in SIV-Infected Rhesus Macaques. PLoS Pathog (2015) 1.42
Autoimmune manifestations in aged mice arise from early-life immune dysregulation. Sci Transl Med (2016) 1.40
Harnessing CD4⁺ T cell responses in HIV vaccine development. Nat Med (2013) 1.39
The E3 ubiquitin ligase Itch is required for the differentiation of follicular helper T cells. Nat Immunol (2014) 1.35
IL-12 receptor β1 deficiency alters in vivo T follicular helper cell response in humans. Blood (2013) 1.31
Lineage-specific functions of Bcl-6 in immunity and inflammation are mediated by distinct biochemical mechanisms. Nat Immunol (2013) 1.30
Phenotype and functions of memory Tfh cells in human blood. Trends Immunol (2014) 1.28
Transcriptional regulation of follicular T-helper (Tfh) cells. Immunol Rev (2013) 1.28
A brief history of T cell help to B cells. Nat Rev Immunol (2015) 1.21
ICOS coreceptor signaling inactivates the transcription factor FOXO1 to promote Tfh cell differentiation. Immunity (2015) 1.17
Dynamic regulation of Bcl6 in follicular helper CD4 T (Tfh) cells. Curr Opin Immunol (2013) 1.16
T follicular helper cell diversity and plasticity. Trends Immunol (2013) 1.14
Cell distance mapping identifies functional T follicular helper cells in inflamed human renal tissue. Sci Transl Med (2014) 1.14
BCL6 orchestrates Tfh cell differentiation via multiple distinct mechanisms. J Exp Med (2015) 1.14
Follicular regulatory T cells control humoral autoimmunity via NFAT2-regulated CXCR5 expression. J Exp Med (2014) 1.08
Memory T follicular helper CD4 T cells. Front Immunol (2015) 1.06
Circulating CXCR5+PD-1+ response predicts influenza vaccine antibody responses in young adults but not elderly adults. J Immunol (2014) 1.02
PD-1 coinhibitory signals: the link between pathogenesis and protection. Semin Immunol (2013) 1.01
CXCL13 is a plasma biomarker of germinal center activity. Proc Natl Acad Sci U S A (2016) 0.99
IL-17RA is essential for optimal localization of follicular Th cells in the germinal center light zone to promote autoantibody-producing B cells. J Immunol (2013) 0.99
Circulating Th1-Cell-type Tfh Cells that Exhibit Impaired B Cell Help Are Preferentially Activated during Acute Malaria in Children. Cell Rep (2015) 0.98
Transcriptional and epigenetic regulation of T-helper lineage specification. Immunol Rev (2014) 0.97
Rhesus macaque lymph node PD-1(hi)CD4+ T cells express high levels of CXCR5 and IL-21 and display a CCR7(lo)ICOS+Bcl6+ T-follicular helper (Tfh) cell phenotype. PLoS One (2013) 0.96
Molecular profiling of CD8 T cells in autochthonous melanoma identifies Maf as driver of exhaustion. EMBO J (2015) 0.96
Complex interactions of transcription factors in mediating cytokine biology in T cells. Immunol Rev (2014) 0.93
Tailored immune responses: novel effector helper T cell subsets in protective immunity. PLoS Pathog (2014) 0.92
A Cytokine-Independent Approach To Identify Antigen-Specific Human Germinal Center T Follicular Helper Cells and Rare Antigen-Specific CD4+ T Cells in Blood. J Immunol (2016) 0.92
New effector functions and regulatory mechanisms of BCL6 in normal and malignant lymphocytes. Curr Opin Immunol (2013) 0.91
Modulation of SAP dependent T:B cell interactions as a strategy to improve vaccination. Curr Opin Virol (2013) 0.89
Id2 reinforces TH1 differentiation and inhibits E2A to repress TFH differentiation. Nat Immunol (2016) 0.88
Codelivery of Envelope Protein in Alum with MVA Vaccine Induces CXCR3-Biased CXCR5+ and CXCR5- CD4 T Cell Responses in Rhesus Macaques. J Immunol (2015) 0.88
The histopathology of labial salivary glands in primary Sjögren's syndrome: focusing on follicular helper T cells in the inflammatory infiltrates. Mediators Inflamm (2014) 0.87
Cutting edge: T follicular helper cell differentiation is defective in the absence of Bcl6 BTB repressor domain function. J Immunol (2015) 0.87
Cytokine-Independent Detection of Antigen-Specific Germinal Center T Follicular Helper Cells in Immunized Nonhuman Primates Using a Live Cell Activation-Induced Marker Technique. J Immunol (2016) 0.86
Emerging concepts on T follicular helper cell dynamics in HIV infection. Trends Immunol (2014) 0.85
The differential expression of IL-4 and IL-13 and its impact on type-2 immunity. Cytokine (2015) 0.84
Successive annual influenza vaccination induces a recurrent oligoclonotypic memory response in circulating T follicular helper cells. Sci Immunol (2017) 0.84
Memory B cells form in aged mice despite impaired affinity maturation and germinal center kinetics. Exp Gerontol (2014) 0.83
Reduced TET2 function leads to T-cell lymphoma with follicular helper T-cell-like features in mice. Blood Cancer J (2014) 0.83
Increased frequency of circulating follicular helper T cells in children with hand, foot, and mouth disease caused by enterovirus 71 infection. J Immunol Res (2014) 0.82
Human Th17 Cells Lack HIV-Inhibitory RNases and Are Highly Permissive to Productive HIV Infection. J Virol (2016) 0.81
The role of interleukin-21 in HIV infection. Cytokine Growth Factor Rev (2012) 0.81
Expansion or depletion of T follicular helper cells during HIV infection: consequences for B cell responses. Curr HIV Res (2013) 0.80
Higher Frequency of Circulating PD-1(high) CXCR5(+)CD4(+) Tfh Cells in Patients with Chronic Schistosomiasis. Int J Biol Sci (2015) 0.80
Plasticity is the differentiated state of CD4 T cells. Cell Mol Immunol (2013) 0.80
The importance of co-stimulation in the orchestration of T helper cell differentiation. Immunol Cell Biol (2015) 0.80
A distinct subpopulation of CD25(-) T-follicular regulatory cells localizes in the germinal centers. Proc Natl Acad Sci U S A (2017) 0.79
Changes in follicular helper T cells in idiopathic thrombocytopenic purpura patients. Int J Biol Sci (2015) 0.79
Bcl6 middle domain repressor function is required for T follicular helper cell differentiation and utilizes the corepressor MTA3. Proc Natl Acad Sci U S A (2015) 0.79
PU.1 Expression in T Follicular Helper Cells Limits CD40L-Dependent Germinal Center B Cell Development. J Immunol (2015) 0.79
Aging, cytomegalovirus (CMV) and influenza vaccine responses. Hum Vaccin Immunother (2016) 0.79
IL-21 restricts T follicular regulatory T cell proliferation through Bcl-6 mediated inhibition of responsiveness to IL-2. Nat Commun (2017) 0.79
Increased frequency of bone marrow T follicular helper cells in patients with immune-related pancytopenia. Clin Dev Immunol (2013) 0.78
CD25(+) Bcl6(low) T follicular helper cells provide help to maturing B cells in germinal centers of human tonsil. Eur J Immunol (2014) 0.78
Expansion of Circulating T Follicular Helper Cells in Children with Acute Henoch-Schönlein Purpura. J Immunol Res (2015) 0.76
The curious origins of angioimmunoblastic T-cell lymphoma. Curr Opin Hematol (2016) 0.76
Insights into the development and regulation of T follicular helper cells. Cytokine (2016) 0.76
Follicular Helper T (Tfh) Cells in Autoimmune Diseases and Allograft Rejection. Immune Netw (2016) 0.76
T follicular helper cell programming by cytokine-mediated events. Immunology (2016) 0.76
Bob1 limits cellular frequency of T-follicular helper cells. Eur J Immunol (2016) 0.76
The transcriptional coactivator Bob1 promotes the development of follicular T helper cells via Bcl6. EMBO J (2016) 0.75
Implications of Intravital Imaging of Murine Germinal Centers on the Control of B Cell Selection and Division. Front Immunol (2016) 0.75
A Novel Rabies Vaccine Expressing CXCL13 Enhances Humoral Immunity by Recruiting both T Follicular Helper and Germinal Center B Cells. J Virol (2016) 0.75
Ribosomal and immune transcripts associate with relapse in acquired ADAMTS13-deficient thrombotic thrombocytopenic purpura. PLoS One (2015) 0.75
MAF drives CD8(+) T-cell exhaustion. Oncoimmunology (2015) 0.75
Identification of STOML2 as a putative novel asthma risk gene associated with IL6R. Allergy (2016) 0.75
Regulators of Tfh Cell Differentiation. Front Immunol (2016) 0.75
Myor/ABF-1 mRNA [corrected] Expression Marks Follicular Helper T Cells but Is Dispensable for Tfh Cell Differentiation and Function In Vivo. PLoS One (2013) 0.75
TSLP-activated dendritic cells induce human T follicular helper cell differentiation through OX40-ligand. J Exp Med (2017) 0.75
T follicular helper cells in patients with acute schistosomiasis. Parasit Vectors (2016) 0.75
CD4 T Follicular Helper Cells and HIV Infection: Friends or Enemies? Front Immunol (2017) 0.75
CD4 memory T cells develop and acquire functional competence by sequential cognate interactions and stepwise gene regulation. Int Immunol (2015) 0.75
Transcriptomic responses of water buffalo liver to infection with the digenetic fluke Fasciola gigantica. Parasit Vectors (2017) 0.75
Bcl6 promotes follicular helper T-cell differentiation and PD-1 expression in a Blimp1-independent manner in mice. Eur J Immunol (2017) 0.75
Impact of Aging and Cytomegalovirus on Immunological Response to Influenza Vaccination and Infection. Front Immunol (2017) 0.75
Differential Requirements for Tcf1 Long Isoforms in CD8(+) and CD4(+) T Cell Responses to Acute Viral Infection. J Immunol (2017) 0.75
The Transcription Factor c-Maf Promotes the Differentiation of Follicular Helper T Cells. Front Immunol (2017) 0.75
Follicular helper CD4 T cells (TFH). Annu Rev Immunol (2011) 12.50
Differentiation of effector CD4 T cell populations (*). Annu Rev Immunol (2010) 11.80
Bcl6 and Blimp-1 are reciprocal and antagonistic regulators of T follicular helper cell differentiation. Science (2009) 9.22
Bcl6 mediates the development of T follicular helper cells. Science (2009) 8.50
The transcriptional repressor Bcl-6 directs T follicular helper cell lineage commitment. Immunity (2009) 7.69
A critical role for IL-21 in regulating immunoglobulin production. Science (2002) 7.09
Control of inflammation, cytokine expression, and germinal center formation by BCL-6. Science (1997) 6.58
Germinal centres: role in B-cell physiology and malignancy. Nat Rev Immunol (2008) 6.09
The costimulatory molecule ICOS regulates the expression of c-Maf and IL-21 in the development of follicular T helper cells and TH-17 cells. Nat Immunol (2008) 5.92
Vaccines: correlates of vaccine-induced immunity. Clin Infect Dis (2008) 5.69
ICOS receptor instructs T follicular helper cell versus effector cell differentiation via induction of the transcriptional repressor Bcl6. Immunity (2011) 5.59
The BCL-6 proto-oncogene controls germinal-centre formation and Th2-type inflammation. Nat Genet (1997) 5.55
T follicular helper cells express a distinctive transcriptional profile, reflecting their role as non-Th1/Th2 effector cells that provide help for B cells. J Immunol (2004) 5.53
SAP-controlled T-B cell interactions underlie germinal centre formation. Nature (2008) 5.14
Role of CXCR5 and CCR7 in follicular Th cell positioning and appearance of a programmed cell death gene-1high germinal center-associated subpopulation. J Immunol (2007) 5.14
CD40 ligand gene defects responsible for X-linked hyper-IgM syndrome. Science (1993) 5.04
Mice deficient for the CD40 ligand. Immunity (1994) 4.45
Follicular helper T cells are required for systemic autoimmunity. J Exp Med (2009) 4.25
Germinal center dark and light zone organization is mediated by CXCR4 and CXCR5. Nat Immunol (2004) 4.22
IL-21 regulates germinal center B cell differentiation and proliferation through a B cell-intrinsic mechanism. J Exp Med (2010) 4.04
SAP is required for generating long-term humoral immunity. Nature (2003) 3.85
Follicular B helper T cell activity is confined to CXCR5(hi)ICOS(hi) CD4 T cells and is independent of CD57 expression. Eur J Immunol (2006) 3.85
Subspecialization of CXCR5+ T cells: B helper activity is focused in a germinal center-localized subset of CXCR5+ T cells. J Exp Med (2001) 3.71
BCL6 enables Ph+ acute lymphoblastic leukaemia cells to survive BCR-ABL1 kinase inhibition. Nature (2011) 3.63
The transcription factor c-Maf controls the production of interleukin-4 but not other Th2 cytokines. Immunity (1999) 3.61
PD-1 regulates germinal center B cell survival and the formation and affinity of long-lived plasma cells. Nat Immunol (2010) 3.51
Early commitment of naïve human CD4(+) T cells to the T follicular helper (T(FH)) cell lineage is induced by IL-12. Immunol Cell Biol (2009) 3.51
Effectors and memories: Bcl-6 and Blimp-1 in T and B lymphocyte differentiation. Nat Immunol (2010) 3.48
Humoral immune responses in CD40 ligand-deficient mice. J Exp Med (1994) 3.32
IL-4-producing CD4+ T cells in reactive lymph nodes during helminth infection are T follicular helper cells. J Exp Med (2009) 3.18
BCL-6 protein is expressed in germinal-center B cells. Blood (1995) 3.18
Homozygous loss of ICOS is associated with adult-onset common variable immunodeficiency. Nat Immunol (2003) 3.16
Effector T cell plasticity: flexibility in the face of changing circumstances. Nat Immunol (2010) 3.12
ICOS deficiency is associated with a severe reduction of CXCR5+CD4 germinal center Th cells. J Immunol (2006) 2.99
IL-21 and IL-6 are critical for different aspects of B cell immunity and redundantly induce optimal follicular helper CD4 T cell (Tfh) differentiation. PLoS One (2011) 2.92
gp39-CD40 interactions are essential for germinal center formation and the development of B cell memory. J Exp Med (1994) 2.87
Germinal center T follicular helper cell IL-4 production is dependent on signaling lymphocytic activation molecule receptor (CD150). J Immunol (2010) 2.85
BLC expression in pancreatic islets causes B cell recruitment and lymphotoxin-dependent lymphoid neogenesis. Immunity (2000) 2.79
Cellular interaction in germinal centers. Roles of CD40 ligand and B7-2 in established germinal centers. J Immunol (1995) 2.72
Regulation of homeostatic chemokine expression and cell trafficking during immune responses. Science (2007) 2.67
Follicular stromal cells and lymphocyte homing to follicles. Immunol Rev (2000) 2.66
Bcl6 protein expression shapes pre-germinal center B cell dynamics and follicular helper T cell heterogeneity. Immunity (2011) 2.60
CXCR5 expressing human central memory CD4 T cells and their relevance for humoral immune responses. J Immunol (2011) 2.54
SLAM family receptors and SAP adaptors in immunity. Annu Rev Immunol (2011) 2.52
Dysregulation of germinal centres in autoimmune disease. Nat Rev Immunol (2009) 2.43
Unique gene expression program of human germinal center T helper cells. Blood (2004) 2.40
The inducible costimulator (ICOS) is critical for the development of human T(H)17 cells. Sci Transl Med (2010) 2.40
CD40 ligand-transduced co-stimulation of T cells in the development of helper function. Nature (1995) 2.23
EBI2 mediates B cell segregation between the outer and centre follicle. Nature (2009) 2.20
Follicular dendritic cell networks of primary follicles and germinal centers: phenotype and function. Semin Immunol (2008) 2.20
Oxysterols direct immune cell migration via EBI2. Nature (2011) 2.19
Complete correction of murine Artemis immunodeficiency by lentiviral vector-mediated gene transfer. Proc Natl Acad Sci U S A (2006) 2.17
Guidance of B cells by the orphan G protein-coupled receptor EBI2 shapes humoral immune responses. Immunity (2009) 2.09
The BCL6 transcriptional program features repression of multiple oncogenes in primary B cells and is deregulated in DLBCL. Blood (2009) 2.04
Generation of stable monoclonal antibody-producing B cell receptor-positive human memory B cells by genetic programming. Nat Med (2009) 2.03
Oxysterols direct B-cell migration through EBI2. Nature (2011) 1.94
Impaired humoral immunity in X-linked lymphoproliferative disease is associated with defective IL-10 production by CD4+ T cells. J Clin Invest (2005) 1.92
Immunological memory in humans. Semin Immunol (2004) 1.90
CD40 ligand-deficient mice generate a normal primary cytotoxic T-lymphocyte response but a defective humoral response to a viral infection. J Virol (1996) 1.74
The elusive identity of T follicular helper cells. Trends Immunol (2010) 1.67
Integrated biochemical and computational approach identifies BCL6 direct target genes controlling multiple pathways in normal germinal center B cells. Blood (2009) 1.64
Human ICOS deficiency abrogates the germinal center reaction and provides a monogenic model for common variable immunodeficiency. Blood (2005) 1.63
In situ B cell-mediated immune responses and tubulointerstitial inflammation in human lupus nephritis. J Immunol (2010) 1.54
Plasticity and heterogeneity in the generation of memory B cells and long-lived plasma cells: the influence of germinal center interactions and dynamics. J Immunol (2010) 1.51
Human tonsil B-cell lymphoma 6 (BCL6)-expressing CD4+ T-cell subset specialized for B-cell help outside germinal centers. Proc Natl Acad Sci U S A (2011) 1.50
Blockade of B7-H1 (programmed death ligand 1) enhances humoral immunity by positively regulating the generation of T follicular helper cells. J Immunol (2011) 1.47
c-Maf activates the promoter and enhancer of the IL-21 gene, and TGF-beta inhibits c-Maf-induced IL-21 production in CD4+ T cells. J Leukoc Biol (2009) 1.38
B7RP-1 blockade ameliorates autoimmunity through regulation of follicular helper T cells. J Immunol (2009) 1.38
Interleukin-4-mediated protection of primary B cells from apoptosis through Stat6-dependent up-regulation of Bcl-xL. J Biol Chem (2002) 1.34
BCL6 repression of EP300 in human diffuse large B cell lymphoma cells provides a basis for rational combinatorial therapy. J Clin Invest (2010) 1.26
Expression of two markers of germinal center T cells (SAP and PD-1) in angioimmunoblastic T-cell lymphoma. Haematologica (2007) 1.25
Follicular dendritic cell regulation of CXCR4-mediated germinal center CD4 T cell migration. J Immunol (2004) 1.25
Cutting edge: induction of follicular homing precedes effector Th cell development. J Immunol (2001) 1.17
Upregulation of PD-1 expression on HIV-specific CD8+ T cells leads to reversible immune dysfunction. Nat Med (2006) 13.15
Bcl6 and Blimp-1 are reciprocal and antagonistic regulators of T follicular helper cell differentiation. Science (2009) 9.22
HIV reservoir size and persistence are driven by T cell survival and homeostatic proliferation. Nat Med (2009) 8.45
ICOS receptor instructs T follicular helper cell versus effector cell differentiation via induction of the transcriptional repressor Bcl6. Immunity (2011) 5.59
Resolution of a chronic viral infection after interleukin-10 receptor blockade. J Exp Med (2006) 4.97
Yellow fever vaccine induces integrated multilineage and polyfunctional immune responses. J Exp Med (2008) 4.21
Programmed death-1-induced interleukin-10 production by monocytes impairs CD4+ T cell activation during HIV infection. Nat Med (2010) 3.81
Human circulating PD-1+CXCR3-CXCR5+ memory Tfh cells are highly functional and correlate with broadly neutralizing HIV antibody responses. Immunity (2013) 3.72
Profiling the humoral immune response to infection by using proteome microarrays: high-throughput vaccine and diagnostic antigen discovery. Proc Natl Acad Sci U S A (2005) 3.59
STAT5 is a potent negative regulator of TFH cell differentiation. J Exp Med (2012) 3.37
A Blueprint for HIV Vaccine Discovery. Cell Host Microbe (2012) 3.27
IL-21 and IL-6 are critical for different aspects of B cell immunity and redundantly induce optimal follicular helper CD4 T cell (Tfh) differentiation. PLoS One (2011) 2.92
Germinal center T follicular helper cell IL-4 production is dependent on signaling lymphocytic activation molecule receptor (CD150). J Immunol (2010) 2.85
In vivo regulation of Bcl6 and T follicular helper cell development. J Immunol (2010) 2.63
Immunity and immunological memory following smallpox vaccination. Immunol Rev (2006) 2.57
CD4 T follicular helper cell dynamics during SIV infection. J Clin Invest (2012) 2.55
Follicular helper T cells serve as the major CD4 T cell compartment for HIV-1 infection, replication, and production. J Exp Med (2012) 2.46
Selective CD4+ T cell help for antibody responses to a large viral pathogen: deterministic linkage of specificities. Immunity (2008) 2.43
Inadequate T follicular cell help impairs B cell immunity during HIV infection. Nat Med (2013) 2.29
Immune responses to Bacillus anthracis protective antigen in patients with bioterrorism-related cutaneous or inhalation anthrax. J Infect Dis (2004) 2.29
Convergence of TCR and cytokine signaling leads to FOXO3a phosphorylation and drives the survival of CD4+ central memory T cells. J Exp Med (2006) 2.27
The receptor Ly108 functions as a SAP adaptor-dependent on-off switch for T cell help to B cells and NKT cell development. Immunity (2012) 2.19
Vaccinia virus H3L envelope protein is a major target of neutralizing antibodies in humans and elicits protection against lethal challenge in mice. J Virol (2005) 2.18
Proteome-wide analysis of the serological response to vaccinia and smallpox. Proteomics (2007) 2.10
Dual functional roles of dentin matrix protein 1. Implications in biomineralization and gene transcription by activation of intracellular Ca2+ store. J Biol Chem (2003) 2.10
Synthetic double-stranded RNA induces innate immune responses similar to a live viral vaccine in humans. J Exp Med (2011) 2.09
Establishment of HIV-1 latency in resting CD4+ T cells depends on chemokine-induced changes in the actin cytoskeleton. Proc Natl Acad Sci U S A (2010) 2.07
Modulation of cellular mechanics during osteogenic differentiation of human mesenchymal stem cells. Biophys J (2007) 1.97
SAP regulates T cell-mediated help for humoral immunity by a mechanism distinct from cytokine regulation. J Exp Med (2006) 1.92
Early interferon therapy for hepatitis C virus infection rescues polyfunctional, long-lived CD8+ memory T cells. J Virol (2008) 1.90
Transcription factor FOXO3a controls the persistence of memory CD4(+) T cells during HIV infection. Nat Med (2008) 1.85
Biology of CCR5 and its role in HIV infection and treatment. JAMA (2006) 1.84
Redundancy and plasticity of neutralizing antibody responses are cornerstone attributes of the human immune response to the smallpox vaccine. J Virol (2008) 1.77
Bcl6 expressing follicular helper CD4 T cells are fate committed early and have the capacity to form memory. J Immunol (2013) 1.71
Heavily isotype-dependent protective activities of human antibodies against vaccinia virus extracellular virion antigen B5. J Virol (2009) 1.69
SAP regulation of follicular helper CD4 T cell development and humoral immunity is independent of SLAM and Fyn kinase. J Immunol (2007) 1.68
Vaccinia virus-specific CD4+ T cell responses target a set of antigens largely distinct from those targeted by CD8+ T cell responses. J Immunol (2007) 1.66
Cutting edge: STAT1 is required for IL-6-mediated Bcl6 induction for early follicular helper cell differentiation. J Immunol (2013) 1.57
Single-cell gene-expression profiling reveals qualitatively distinct CD8 T cells elicited by different gene-based vaccines. Proc Natl Acad Sci U S A (2011) 1.56
Vaccinia virus extracellular enveloped virion neutralization in vitro and protection in vivo depend on complement. J Virol (2008) 1.49
Quantitative PCR technique for detecting lymphocytic choriomeningitis virus in vivo. J Virol Methods (2007) 1.45
A new theory to explain the genesis of petrous apex cholesterol granuloma. Otol Neurotol (2003) 1.44
Distinct membrane mechanical properties of human mesenchymal stem cells determined using laser optical tweezers. Biophys J (2006) 1.42
Inhibition of NK cell activity by IL-17 allows vaccinia virus to induce severe skin lesions in a mouse model of eczema vaccinatum. J Exp Med (2009) 1.41
Harnessing CD4⁺ T cell responses in HIV vaccine development. Nat Med (2013) 1.39
T-cell exhaustion in HIV infection. Curr HIV/AIDS Rep (2008) 1.38
Ly9 (CD229)-deficient mice exhibit T cell defects yet do not share several phenotypic characteristics associated with SLAM- and SAP-deficient mice. J Immunol (2006) 1.36
NKT cells prevent chronic joint inflammation after infection with Borrelia burgdorferi. Proc Natl Acad Sci U S A (2008) 1.35
Probiotic/prebiotic supplementation of antiretrovirals improves gastrointestinal immunity in SIV-infected macaques. J Clin Invest (2013) 1.35
OX40 drives protective vaccinia virus-specific CD8 T cells. J Immunol (2008) 1.33
CD160 and PD-1 co-expression on HIV-specific CD8 T cells defines a subset with advanced dysfunction. PLoS Pathog (2012) 1.28
Loss of memory B cells during chronic HIV infection is driven by Foxo3a- and TRAIL-mediated apoptosis. J Clin Invest (2011) 1.27
ROCK-II mediates colon cancer invasion via regulation of MMP-2 and MMP-13 at the site of invadopodia as revealed by multiphoton imaging. Lab Invest (2007) 1.22
Therapeutic vaccination with simian immunodeficiency virus (SIV)-DNA + IL-12 or IL-15 induces distinct CD8 memory subsets in SIV-infected macaques. J Immunol (2008) 1.22
Monkeypox-induced immunity and failure of childhood smallpox vaccination to provide complete protection. Clin Vaccine Immunol (2007) 1.20
Physical manipulation of calcium oscillations facilitates osteodifferentiation of human mesenchymal stem cells. FASEB J (2007) 1.16
Improved innate and adaptive immunostimulation by genetically modified HIV-1 protein expressing NYVAC vectors. PLoS One (2011) 1.16
Dynamic regulation of Bcl6 in follicular helper CD4 T (Tfh) cells. Curr Opin Immunol (2013) 1.16
Evidence for long-term efficacy and safety of gene therapy for Wiskott-Aldrich syndrome in preclinical models. Mol Ther (2009) 1.15
Determinants of protection among HIV‐exposed seronegative persons: an overview. J Infect Dis (2010) 1.13
Immune activation alters cellular and humoral responses to yellow fever 17D vaccine. J Clin Invest (2014) 1.12
Treatment of acute gouty arthritis in complex hospitalized patients with anakinra. Arthritis Care Res (Hoboken) (2013) 1.12
B cell-specific expression of B7-2 is required for follicular Th cell function in response to vaccinia virus. J Immunol (2011) 1.10
Regulation of cell cytoskeleton and membrane mechanics by electric field: role of linker proteins. Biophys J (2009) 1.10
Chondrogenic differentiation of human mesenchymal stem cells on oriented nanofibrous scaffolds: engineering the superficial zone of articular cartilage. Tissue Eng Part A (2009) 1.09
Uncovering the interplay between CD8, CD4 and antibody responses to complex pathogens. Future Microbiol (2010) 1.07
Systems analysis of a RIG-I agonist inducing broad spectrum inhibition of virus infectivity. PLoS Pathog (2013) 1.07
OX40 facilitates control of a persistent virus infection. PLoS Pathog (2012) 1.05
The selective increase in caspase-3 expression in effector but not memory T cells allows susceptibility to apoptosis. J Immunol (2004) 1.05
Improved NYVAC-based vaccine vectors. PLoS One (2011) 1.04
Lentiviral-mediated gene therapy leads to improvement of B-cell functionality in a murine model of Wiskott-Aldrich syndrome. J Allergy Clin Immunol (2011) 1.03
Profound metabolic, functional, and cytolytic differences characterize HIV-specific CD8 T cells in primary and chronic HIV infection. Blood (2012) 1.03
Simulation training and its effect on long-term resident performance in central venous catheterization. Simul Healthc (2010) 1.02
Combination therapy of vaccinia virus infection with human anti-H3 and anti-B5 monoclonal antibodies in a small animal model. Antivir Ther (2010) 1.02
Caspase-3 is a component of Fas death-inducing signaling complex in lipid rafts and its activity is required for complete caspase-8 activation during Fas-mediated cell death. J Immunol (2004) 1.02
oxLDL-induced decrease in lipid order of membrane domains is inversely correlated with endothelial stiffness and network formation. Am J Physiol Cell Physiol (2010) 1.01
Chronic lymphocytic choriomeningitis virus infection actively down-regulates CD4+ T cell responses directed against a broad range of epitopes. J Immunol (2007) 1.00
Regulation of mesenchymal stem cell adhesion and orientation in 3D collagen scaffold by electrical stimulus. Bioelectrochemistry (2006) 0.98
The smallpox vaccine induces an early neutralizing IgM response. Vaccine (2009) 0.97
Molecular basis for the interaction of four different classes of substrates and inhibitors with human aromatase. Biochem Pharmacol (2007) 0.97
Virus inhibition activity of effector memory CD8(+) T cells determines simian immunodeficiency virus load in vaccinated monkeys after vaccine breakthrough infection. J Virol (2012) 0.97
Myeloid dendritic cells induce HIV-1 latency in non-proliferating CD4+ T cells. PLoS Pathog (2013) 0.97
Altered membrane dynamics of quantum dot-conjugated integrins during osteogenic differentiation of human bone marrow derived progenitor cells. Biophys J (2006) 0.96
Lymph node architecture collapse and consequent modulation of FOXO3a pathway on memory T- and B-cells during HIV infection. Semin Immunol (2008) 0.96
Optimal replication of poliovirus within cells. Am Nat (2005) 0.95
Differential gene expression of periodontal ligament cells after loading of static compressive force. J Periodontol (2007) 0.94
Investigation of hyperpolarized 3He magnetic resonance imaging utility in examining human airway diameter behavior in asthma through comparison with high-resolution computed tomography. Acad Radiol (2008) 0.93
Biochemical and biological characterization of a novel anti-aromatase coumarin derivative. J Biol Chem (2004) 0.92
Structure-function studies of aromatase and its inhibitors: a progress report. J Steroid Biochem Mol Biol (2003) 0.92
Global analyses revealed age-related alterations in innate immune responses after stimulation of pathogen recognition receptors. Aging Cell (2015) 0.92
tert-Butylhydroquinone (tBHQ) protects hepatocytes against lipotoxicity via inducing autophagy independently of Nrf2 activation. Biochim Biophys Acta (2013) 0.91
An epitope conserved in orthopoxvirus A13 envelope protein is the target of neutralizing and protective antibodies. Virology (2011) 0.91
Generative Method to Discover Genetically Driven Image Biomarkers. Inf Process Med Imaging (2015) 0.91