Published in Mech Dev on December 08, 2004
The translation initiation factor 3f (eIF3f) exhibits a deubiquitinase activity regulating Notch activation. PLoS Biol (2010) 1.77
eIF4E: new family members, new binding partners, new roles. J Biol Chem (2009) 1.42
Translational control in cellular and developmental processes. Nat Rev Genet (2012) 1.39
Phylogenetic analysis of eIF4E-family members. BMC Evol Biol (2005) 1.29
Network-level molecular evolutionary analysis of the insulin/TOR signal transduction pathway across 12 Drosophila genomes. Genome Res (2009) 1.20
Translational control of meiotic cell cycle progression and spermatid differentiation in male germ cells by a novel eIF4G homolog. Development (2007) 1.08
Regulation of cell growth by Notch signaling and its differential requirement in normal vs. tumor-forming stem cells in Drosophila. Genes Dev (2011) 1.08
mRNA localization and translational control in Drosophila oogenesis. Cold Spring Harb Perspect Biol (2012) 1.06
Rheb-TOR signaling promotes protein synthesis, but not glucose or amino acid import, in Drosophila. BMC Biol (2007) 1.05
An insight into the transcriptome of the digestive tract of the bloodsucking bug, Rhodnius prolixus. PLoS Negl Trop Dis (2014) 1.03
Binding specificities and potential roles of isoforms of eukaryotic initiation factor 4E in Leishmania. Eukaryot Cell (2006) 1.01
Regulation of neurogenesis and epidermal growth factor receptor signaling by the insulin receptor/target of rapamycin pathway in Drosophila. Genetics (2008) 0.96
Eukaryotic initiation factor 4E-3 is essential for meiotic chromosome segregation, cytokinesis and male fertility in Drosophila. Development (2012) 0.92
New insights into the regulation of RNP granule assembly in oocytes. Int Rev Cell Mol Biol (2012) 0.88
Power of yeast for analysis of eukaryotic translation initiation. J Biol Chem (2010) 0.86
Investigating the consequences of eIF4E2 (4EHP) interaction with 4E-transporter on its cellular distribution in HeLa cells. PLoS One (2013) 0.85
Translation initiation factor AteIF(iso)4E is involved in selective mRNA translation in Arabidopsis thaliana seedlings. PLoS One (2012) 0.82
The Distribution of eIF4E-Family Members across Insecta. Comp Funct Genomics (2012) 0.81
Two Arabidopsis loci encode novel eukaryotic initiation factor 4E isoforms that are functionally distinct from the conserved plant eukaryotic initiation factor 4E. Plant Physiol (2014) 0.81
The histone demethylase dKDM5/LID interacts with the SIN3 histone deacetylase complex and shares functional similarities with SIN3. Epigenetics Chromatin (2016) 0.80
Mextli is a novel eukaryotic translation initiation factor 4E-binding protein that promotes translation in Drosophila melanogaster. Mol Cell Biol (2013) 0.79
On the Diversification of the Translation Apparatus across Eukaryotes. Comp Funct Genomics (2012) 0.79
Diversity of Eukaryotic Translational Initiation Factor eIF4E in Protists. Comp Funct Genomics (2012) 0.79
Loss-of-function analysis reveals distinct requirements of the translation initiation factors eIF4E, eIF4E-3, eIF4G and eIF4G2 in Drosophila spermatogenesis. PLoS One (2015) 0.78
The alveolate translation initiation factor 4E family reveals a custom toolkit for translational control in core dinoflagellates. BMC Evol Biol (2015) 0.77
Positive mRNA Translational Control in Germ Cells by Initiation Factor Selectivity. Biomed Res Int (2015) 0.76
Versatility of the translational machinery during stress: changing partners to keep dancing. Cell Res (2012) 0.75
The Extracellular-Regulated Kinase Effector Lk6 is Required for Glutamate Receptor Localization at the Drosophila Neuromuscular Junction. J Exp Neurosci (2016) 0.75
Distinct recruitment of human eIF4E isoforms to processing bodies and stress granules. BMC Mol Biol (2016) 0.75
The translation factors of Drosophila melanogaster. Fly (Austin) (2016) 0.75
Translational repression of the Drosophila nanos mRNA involves the RNA helicase Belle and RNA coating by Me31B and Trailer hitch. RNA (2017) 0.75
GIGYF1/2 proteins use auxiliary sequences to selectively bind to 4EHP and repress target mRNA expression. Genes Dev (2017) 0.75
Single-stranded antisense siRNAs guide target RNA cleavage in RNAi. Cell (2002) 14.37
Molecular anatomy of a trafficking organelle. Cell (2006) 11.47
Sertraline treatment of major depression in patients with acute MI or unstable angina. JAMA (2002) 8.28
Ambra1 regulates autophagy and development of the nervous system. Nature (2007) 6.94
Identification of novel argonaute-associated proteins. Curr Biol (2005) 6.13
A role for eIF4E and eIF4E-transporter in targeting mRNPs to mammalian processing bodies. RNA (2005) 4.99
Proteomic and functional analysis of Argonaute-containing mRNA-protein complexes in human cells. EMBO Rep (2007) 3.89
Small nuclear ribonucleoprotein remodeling during catalytic activation of the spliceosome. Science (2002) 3.59
Serum protein markers for early detection of ovarian cancer. Proc Natl Acad Sci U S A (2005) 3.22
Protein composition of human prespliceosomes isolated by a tobramycin affinity-selection method. Proc Natl Acad Sci U S A (2002) 3.14
CASK Functions as a Mg2+-independent neurexin kinase. Cell (2008) 3.10
Isolation of an active step I spliceosome and composition of its RNP core. Nature (2008) 3.10
Importin 8 is a gene silencing factor that targets argonaute proteins to distinct mRNAs. Cell (2009) 2.98
GraFix: sample preparation for single-particle electron cryomicroscopy. Nat Methods (2007) 2.71
Protein composition and electron microscopy structure of affinity-purified human spliceosomal B complexes isolated under physiological conditions. Mol Cell Biol (2006) 2.55
EF-P is essential for rapid synthesis of proteins containing consecutive proline residues. Science (2012) 2.44
Characterization of novel SF3b and 17S U2 snRNP proteins, including a human Prp5p homologue and an SF3b DEAD-box protein. EMBO J (2002) 2.39
The evolutionarily conserved core design of the catalytic activation step of the yeast spliceosome. Mol Cell (2009) 2.39
Functional interaction between PML and SATB1 regulates chromatin-loop architecture and transcription of the MHC class I locus. Nat Cell Biol (2006) 2.29
Crystal structure of the yeast eIF4A-eIF4G complex: an RNA-helicase controlled by protein-protein interactions. Proc Natl Acad Sci U S A (2008) 2.24
A subset of human 35S U5 proteins, including Prp19, function prior to catalytic step 1 of splicing. EMBO J (2004) 2.20
A KRAS-variant in ovarian cancer acts as a genetic marker of cancer risk. Cancer Res (2010) 2.15
Mechanism and consequences for paralog-specific sumoylation of ubiquitin-specific protease 25. Mol Cell (2008) 2.15
Composition and three-dimensional EM structure of double affinity-purified, human prespliceosomal A complexes. EMBO J (2007) 2.07
Hierarchy of resistance to cervical neoplasia mediated by combinations of killer immunoglobulin-like receptor and human leukocyte antigen loci. J Exp Med (2005) 2.06
Identification, cloning, and functional analysis of the human U6 snRNA-specific terminal uridylyl transferase. RNA (2006) 2.05
Assembly and maturation of the U3 snoRNP in the nucleoplasm in a large dynamic multiprotein complex. Mol Cell (2004) 1.89
Reconstitution of both steps of Saccharomyces cerevisiae splicing with purified spliceosomal components. Nat Struct Mol Biol (2009) 1.89
Exon definition complexes contain the tri-snRNP and can be directly converted into B-like precatalytic splicing complexes. Mol Cell (2010) 1.84
Protein composition of human mRNPs spliced in vitro and differential requirements for mRNP protein recruitment. RNA (2006) 1.83
Hierarchical, clustered protein interactions with U4/U6 snRNA: a biochemical role for U4/U6 proteins. EMBO J (2002) 1.82
A cytoplasmic complex mediates specific mRNA recognition and localization in yeast. PLoS Biol (2011) 1.78
A reversibly photoswitchable GFP-like protein with fluorescence excitation decoupled from switching. Nat Biotechnol (2011) 1.74
Phosphorylation of human PRP28 by SRPK2 is required for integration of the U4/U6-U5 tri-snRNP into the spliceosome. Nat Struct Mol Biol (2008) 1.73
The human 18S U11/U12 snRNP contains a set of novel proteins not found in the U2-dependent spliceosome. RNA (2004) 1.67
Conservation of the protein composition and electron microscopy structure of Drosophila melanogaster and human spliceosomal complexes. Mol Cell Biol (2008) 1.64
Phosphorylation of human Argonaute proteins affects small RNA binding. Nucleic Acids Res (2010) 1.64
Syk kinase-coupled C-type lectin receptors engage protein kinase C-σ to elicit Card9 adaptor-mediated innate immunity. Immunity (2012) 1.61
The nuclear F-actin interactome of Xenopus oocytes reveals an actin-bundling kinesin that is essential for meiotic cytokinesis. EMBO J (2013) 1.58
B cell receptor-mediated antigen gathering requires ubiquitin ligase Cbl and adaptors Grb2 and Dok-3 to recruit dynein to the signaling microcluster. Immunity (2011) 1.53
Selective pharmacological targeting of a DEAD box RNA helicase. PLoS One (2008) 1.49
Semiquantitative proteomic analysis of the human spliceosome via a novel two-dimensional gel electrophoresis method. Mol Cell Biol (2011) 1.48
Molecular architecture of the human Prp19/CDC5L complex. Mol Cell Biol (2010) 1.44
Detecting endogenous SUMO targets in mammalian cells and tissues. Nat Struct Mol Biol (2013) 1.44
A novel rare variant in SCN1Bb linked to Brugada syndrome and SIDS by combined modulation of Na(v)1.5 and K(v)4.3 channel currents. Heart Rhythm (2011) 1.43
Women's choice between sentinel lymph node biopsy and axillary clearance. ANZ J Surg (2002) 1.42
Characterization of the cleavage site and function of resulting cleavage fragments after limited proteolysis of Clostridium difficile toxin B (TcdB) by host cells. Microbiology (2005) 1.40
MINOS1 is a conserved component of mitofilin complexes and required for mitochondrial function and cristae organization. Mol Biol Cell (2011) 1.37
Structural and functional analysis of the E. coli NusB-S10 transcription antitermination complex. Mol Cell (2008) 1.37
Post-transcriptional spliceosomes are retained in nuclear speckles until splicing completion. Nat Commun (2012) 1.35
Anle138b: a novel oligomer modulator for disease-modifying therapy of neurodegenerative diseases such as prion and Parkinson's disease. Acta Neuropathol (2013) 1.34
A Syd-1 homologue regulates pre- and postsynaptic maturation in Drosophila. J Cell Biol (2010) 1.33
Quantitative comparison of glutamatergic and GABAergic synaptic vesicles unveils selectivity for few proteins including MAL2, a novel synaptic vesicle protein. J Neurosci (2010) 1.32
Fragile X mental retardation protein (FMRP) binds specifically to the brain cytoplasmic RNAs BC1/BC200 via a novel RNA-binding motif. J Biol Chem (2005) 1.32
PERILIPIN-dependent control of lipid droplet structure and fat storage in Drosophila. Cell Metab (2010) 1.31
Systematic analysis of barrier-forming FG hydrogels from Xenopus nuclear pore complexes. EMBO J (2012) 1.27
Mutagenesis suggests several roles of Snu114p in pre-mRNA splicing. J Biol Chem (2003) 1.27
Role of cdk2 in the sequential phosphorylation/activation of C/EBPbeta during adipocyte differentiation. Proc Natl Acad Sci U S A (2007) 1.25
RNA structure and RNA-protein interactions in purified yeast U6 snRNPs. J Mol Biol (2005) 1.20
Determination of protein stoichiometry within protein complexes using absolute quantification and multiple reaction monitoring. Anal Chem (2010) 1.20
Localization of a promoter in the putative internal ribosome entry site of the Saccharomyces cerevisiae TIF4631 gene. RNA (2004) 1.20
Effects of a nursing intervention on quality of life outcomes in post-surgical women with gynecological cancers. Psychooncology (2009) 1.19
Identification of SNAP-47, a novel Qbc-SNARE with ubiquitous expression. J Biol Chem (2006) 1.19
Internal initiation drives the synthesis of Ure2 protein lacking the prion domain and affects [URE3] propagation in yeast cells. EMBO J (2003) 1.18
Dissection of the factor requirements for spliceosome disassembly and the elucidation of its dissociation products using a purified splicing system. Genes Dev (2013) 1.18
The mouse homeobox gene Not is required for caudal notochord development and affected by the truncate mutation. Genes Dev (2004) 1.17
The Prp8 RNase H-like domain inhibits Brr2-mediated U4/U6 snRNA unwinding by blocking Brr2 loading onto the U4 snRNA. Genes Dev (2012) 1.17
Stalling of spliceosome assembly at distinct stages by small-molecule inhibitors of protein acetylation and deacetylation. RNA (2008) 1.16
In vivo expression and purification of aptamer-tagged small RNA regulators. Nucleic Acids Res (2009) 1.15
Ubiquitin-specific protease-like 1 (USPL1) is a SUMO isopeptidase with essential, non-catalytic functions. EMBO Rep (2012) 1.15
Identification of CRM1-dependent Nuclear Export Cargos Using Quantitative Mass Spectrometry. Mol Cell Proteomics (2012) 1.14
Sumoylation inhibits alpha-synuclein aggregation and toxicity. J Cell Biol (2011) 1.13
"ChopNSpice," a mass spectrometric approach that allows identification of endogenous small ubiquitin-like modifier-conjugated peptides. Mol Cell Proteomics (2009) 1.13
RNA-binding activity of translation initiation factor eIF4G1 from Saccharomyces cerevisiae. RNA (2003) 1.12
Internal ribosome entry site drives cap-independent translation of reaper and heat shock protein 70 mRNAs in Drosophila embryos. RNA (2004) 1.11
ERCC1 genotype and phenotype in epithelial ovarian cancer identify patients likely to benefit from paclitaxel treatment in addition to platinum-based therapy. J Clin Oncol (2007) 1.10
Macrophage migration inhibitory factor expression in ovarian cancer. Am J Obstet Gynecol (2007) 1.09
RACK1 is a novel interaction partner of PTK7 that is required for neural tube closure. Development (2011) 1.09
Crystal structure of an intramolecular chaperone mediating triple-beta-helix folding. Nat Struct Mol Biol (2010) 1.08
Apoptosis-based evaluation of chemosensitivity in ovarian cancer patients. J Soc Gynecol Investig (2004) 1.08
Choroid plexus transcytosis and exosome shuttling deliver folate into brain parenchyma. Nat Commun (2013) 1.06
Optic atrophy 1 is an A-kinase anchoring protein on lipid droplets that mediates adrenergic control of lipolysis. EMBO J (2011) 1.06
Human PRP4 kinase is required for stable tri-snRNP association during spliceosomal B complex formation. Nat Struct Mol Biol (2010) 1.06
Phosphorylation drives a dynamic switch in serine/arginine-rich proteins. Structure (2013) 1.05
The cryo-EM structure of the UPF-EJC complex shows UPF1 poised toward the RNA 3' end. Nat Struct Mol Biol (2012) 1.04
Long-term overweight and weight gain in early adulthood in association with risk of endometrial cancer. Int J Cancer (2011) 1.03
Chromatin affinity purification and quantitative mass spectrometry defining the interactome of histone modification patterns. Mol Cell Proteomics (2011) 1.03
Quantitative analysis of synaptic vesicle Rabs uncovers distinct yet overlapping roles for Rab3a and Rab27b in Ca2+-triggered exocytosis. J Neurosci (2010) 1.03
A complex of Cas proteins 5, 6, and 7 is required for the biogenesis and stability of clustered regularly interspaced short palindromic repeats (crispr)-derived rnas (crrnas) in Haloferax volcanii. J Biol Chem (2014) 1.02
Molecular profiling of synaptic vesicle docking sites reveals novel proteins but few differences between glutamatergic and GABAergic synapses. Neuron (2013) 1.02
Binding specificities and potential roles of isoforms of eukaryotic initiation factor 4E in Leishmania. Eukaryot Cell (2006) 1.01
Promoter-specific transcription of insulin-like growth factor-II in epithelial ovarian cancer. Gynecol Oncol (2006) 1.01
Osteoclast-independent bone resorption by fibroblast-like cells. Arthritis Res Ther (2003) 1.01
DDX6 recruits translational silenced human reticulocyte 15-lipoxygenase mRNA to RNP granules. RNA (2010) 1.00
The B-cell antigen receptor signals through a preformed transducer module of SLP65 and CIN85. EMBO J (2011) 1.00
Unique modifications of translation elongation factors. FEBS J (2011) 0.99
Structural analysis of the yeast Dhh1-Pat1 complex reveals how Dhh1 engages Pat1, Edc3 and RNA in mutually exclusive interactions. Nucleic Acids Res (2013) 0.99
Stathmin and tubulin expression and survival of ovarian cancer patients receiving platinum treatment with and without paclitaxel. Cancer (2009) 0.99