PubRank

Henning Urlaub

Author PubWeight™ 219.80‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Single-stranded antisense siRNAs guide target RNA cleavage in RNAi. Cell 2002 14.37
2 Molecular anatomy of a trafficking organelle. Cell 2006 11.47
3 Identification of novel argonaute-associated proteins. Curr Biol 2005 6.13
4 Proteomic and functional analysis of Argonaute-containing mRNA-protein complexes in human cells. EMBO Rep 2007 3.89
5 Small nuclear ribonucleoprotein remodeling during catalytic activation of the spliceosome. Science 2002 3.59
6 Protein composition of human prespliceosomes isolated by a tobramycin affinity-selection method. Proc Natl Acad Sci U S A 2002 3.14
7 CASK Functions as a Mg2+-independent neurexin kinase. Cell 2008 3.10
8 Isolation of an active step I spliceosome and composition of its RNP core. Nature 2008 3.10
9 Importin 8 is a gene silencing factor that targets argonaute proteins to distinct mRNAs. Cell 2009 2.98
10 GraFix: sample preparation for single-particle electron cryomicroscopy. Nat Methods 2007 2.71
11 Protein composition and electron microscopy structure of affinity-purified human spliceosomal B complexes isolated under physiological conditions. Mol Cell Biol 2006 2.55
12 EF-P is essential for rapid synthesis of proteins containing consecutive proline residues. Science 2012 2.44
13 Characterization of novel SF3b and 17S U2 snRNP proteins, including a human Prp5p homologue and an SF3b DEAD-box protein. EMBO J 2002 2.39
14 The evolutionarily conserved core design of the catalytic activation step of the yeast spliceosome. Mol Cell 2009 2.39
15 Functional interaction between PML and SATB1 regulates chromatin-loop architecture and transcription of the MHC class I locus. Nat Cell Biol 2006 2.29
16 A subset of human 35S U5 proteins, including Prp19, function prior to catalytic step 1 of splicing. EMBO J 2004 2.20
17 Mechanism and consequences for paralog-specific sumoylation of ubiquitin-specific protease 25. Mol Cell 2008 2.15
18 Composition and three-dimensional EM structure of double affinity-purified, human prespliceosomal A complexes. EMBO J 2007 2.07
19 Identification, cloning, and functional analysis of the human U6 snRNA-specific terminal uridylyl transferase. RNA 2006 2.05
20 Assembly and maturation of the U3 snoRNP in the nucleoplasm in a large dynamic multiprotein complex. Mol Cell 2004 1.89
21 Reconstitution of both steps of Saccharomyces cerevisiae splicing with purified spliceosomal components. Nat Struct Mol Biol 2009 1.89
22 Exon definition complexes contain the tri-snRNP and can be directly converted into B-like precatalytic splicing complexes. Mol Cell 2010 1.84
23 Protein composition of human mRNPs spliced in vitro and differential requirements for mRNP protein recruitment. RNA 2006 1.83
24 Hierarchical, clustered protein interactions with U4/U6 snRNA: a biochemical role for U4/U6 proteins. EMBO J 2002 1.82
25 A cytoplasmic complex mediates specific mRNA recognition and localization in yeast. PLoS Biol 2011 1.78
26 A reversibly photoswitchable GFP-like protein with fluorescence excitation decoupled from switching. Nat Biotechnol 2011 1.74
27 Phosphorylation of human PRP28 by SRPK2 is required for integration of the U4/U6-U5 tri-snRNP into the spliceosome. Nat Struct Mol Biol 2008 1.73
28 The human 18S U11/U12 snRNP contains a set of novel proteins not found in the U2-dependent spliceosome. RNA 2004 1.67
29 Conservation of the protein composition and electron microscopy structure of Drosophila melanogaster and human spliceosomal complexes. Mol Cell Biol 2008 1.64
30 Phosphorylation of human Argonaute proteins affects small RNA binding. Nucleic Acids Res 2010 1.64
31 Syk kinase-coupled C-type lectin receptors engage protein kinase C-σ to elicit Card9 adaptor-mediated innate immunity. Immunity 2012 1.61
32 The nuclear F-actin interactome of Xenopus oocytes reveals an actin-bundling kinesin that is essential for meiotic cytokinesis. EMBO J 2013 1.58
33 B cell receptor-mediated antigen gathering requires ubiquitin ligase Cbl and adaptors Grb2 and Dok-3 to recruit dynein to the signaling microcluster. Immunity 2011 1.53
34 Semiquantitative proteomic analysis of the human spliceosome via a novel two-dimensional gel electrophoresis method. Mol Cell Biol 2011 1.48
35 Molecular architecture of the human Prp19/CDC5L complex. Mol Cell Biol 2010 1.44
36 Detecting endogenous SUMO targets in mammalian cells and tissues. Nat Struct Mol Biol 2013 1.44
37 Characterization of purified human Bact spliceosomal complexes reveals compositional and morphological changes during spliceosome activation and first step catalysis. RNA 2010 1.43
38 Characterization of the cleavage site and function of resulting cleavage fragments after limited proteolysis of Clostridium difficile toxin B (TcdB) by host cells. Microbiology 2005 1.40
39 Structural and functional analysis of the E. coli NusB-S10 transcription antitermination complex. Mol Cell 2008 1.37
40 MINOS1 is a conserved component of mitofilin complexes and required for mitochondrial function and cristae organization. Mol Biol Cell 2011 1.37
41 Post-transcriptional spliceosomes are retained in nuclear speckles until splicing completion. Nat Commun 2012 1.35
42 Anle138b: a novel oligomer modulator for disease-modifying therapy of neurodegenerative diseases such as prion and Parkinson's disease. Acta Neuropathol 2013 1.34
43 A Syd-1 homologue regulates pre- and postsynaptic maturation in Drosophila. J Cell Biol 2010 1.33
44 Quantitative comparison of glutamatergic and GABAergic synaptic vesicles unveils selectivity for few proteins including MAL2, a novel synaptic vesicle protein. J Neurosci 2010 1.32
45 Fragile X mental retardation protein (FMRP) binds specifically to the brain cytoplasmic RNAs BC1/BC200 via a novel RNA-binding motif. J Biol Chem 2005 1.32
46 PERILIPIN-dependent control of lipid droplet structure and fat storage in Drosophila. Cell Metab 2010 1.31
47 Systematic analysis of barrier-forming FG hydrogels from Xenopus nuclear pore complexes. EMBO J 2012 1.27
48 Mutagenesis suggests several roles of Snu114p in pre-mRNA splicing. J Biol Chem 2003 1.27
49 Role of cdk2 in the sequential phosphorylation/activation of C/EBPbeta during adipocyte differentiation. Proc Natl Acad Sci U S A 2007 1.25
50 RNA structure and RNA-protein interactions in purified yeast U6 snRNPs. J Mol Biol 2005 1.20
51 Determination of protein stoichiometry within protein complexes using absolute quantification and multiple reaction monitoring. Anal Chem 2010 1.20
52 Identification of SNAP-47, a novel Qbc-SNARE with ubiquitous expression. J Biol Chem 2006 1.19
53 Dissection of the factor requirements for spliceosome disassembly and the elucidation of its dissociation products using a purified splicing system. Genes Dev 2013 1.18
54 Functional analysis of seven genes encoding eight translation initiation factor 4E (eIF4E) isoforms in Drosophila. Mech Dev 2004 1.17
55 The Prp8 RNase H-like domain inhibits Brr2-mediated U4/U6 snRNA unwinding by blocking Brr2 loading onto the U4 snRNA. Genes Dev 2012 1.17
56 Stalling of spliceosome assembly at distinct stages by small-molecule inhibitors of protein acetylation and deacetylation. RNA 2008 1.16
57 In vivo expression and purification of aptamer-tagged small RNA regulators. Nucleic Acids Res 2009 1.15
58 Ubiquitin-specific protease-like 1 (USPL1) is a SUMO isopeptidase with essential, non-catalytic functions. EMBO Rep 2012 1.15
59 Identification of CRM1-dependent Nuclear Export Cargos Using Quantitative Mass Spectrometry. Mol Cell Proteomics 2012 1.14
60 Sumoylation inhibits alpha-synuclein aggregation and toxicity. J Cell Biol 2011 1.13
61 "ChopNSpice," a mass spectrometric approach that allows identification of endogenous small ubiquitin-like modifier-conjugated peptides. Mol Cell Proteomics 2009 1.13
62 RACK1 is a novel interaction partner of PTK7 that is required for neural tube closure. Development 2011 1.09
63 Crystal structure of an intramolecular chaperone mediating triple-beta-helix folding. Nat Struct Mol Biol 2010 1.08
64 Choroid plexus transcytosis and exosome shuttling deliver folate into brain parenchyma. Nat Commun 2013 1.06
65 Optic atrophy 1 is an A-kinase anchoring protein on lipid droplets that mediates adrenergic control of lipolysis. EMBO J 2011 1.06
66 Human PRP4 kinase is required for stable tri-snRNP association during spliceosomal B complex formation. Nat Struct Mol Biol 2010 1.06
67 Phosphorylation drives a dynamic switch in serine/arginine-rich proteins. Structure 2013 1.05
68 The cryo-EM structure of the UPF-EJC complex shows UPF1 poised toward the RNA 3' end. Nat Struct Mol Biol 2012 1.04
69 Chromatin affinity purification and quantitative mass spectrometry defining the interactome of histone modification patterns. Mol Cell Proteomics 2011 1.03
70 Quantitative analysis of synaptic vesicle Rabs uncovers distinct yet overlapping roles for Rab3a and Rab27b in Ca2+-triggered exocytosis. J Neurosci 2010 1.03
71 A complex of Cas proteins 5, 6, and 7 is required for the biogenesis and stability of clustered regularly interspaced short palindromic repeats (crispr)-derived rnas (crrnas) in Haloferax volcanii. J Biol Chem 2014 1.02
72 Molecular profiling of synaptic vesicle docking sites reveals novel proteins but few differences between glutamatergic and GABAergic synapses. Neuron 2013 1.02
73 DDX6 recruits translational silenced human reticulocyte 15-lipoxygenase mRNA to RNP granules. RNA 2010 1.00
74 The B-cell antigen receptor signals through a preformed transducer module of SLP65 and CIN85. EMBO J 2011 1.00
75 Structural analysis of the yeast Dhh1-Pat1 complex reveals how Dhh1 engages Pat1, Edc3 and RNA in mutually exclusive interactions. Nucleic Acids Res 2013 0.99
76 SMN-assisted assembly of snRNP-specific Sm cores in trypanosomes. Genes Dev 2009 0.99
77 A new paradigm for MAPK: structural interactions of hERK1 with mitochondria in HeLa cells. PLoS One 2009 0.99
78 7SK small nuclear RNA directly affects HMGA1 function in transcription regulation. Nucleic Acids Res 2010 0.99
79 Structure and RNA-binding properties of the Not1-Not2-Not5 module of the yeast Ccr4-Not complex. Nat Struct Mol Biol 2013 0.98
80 Detection of protein-RNA crosslinks by NanoLC-ESI-MS/MS using precursor ion scanning and multiple reaction monitoring (MRM) experiments. J Am Soc Mass Spectrom 2007 0.98
81 In vitro assembly and activity of an archaeal CRISPR-Cas type I-A Cascade interference complex. Nucleic Acids Res 2014 0.98
82 Complete MALDI-ToF MS analysis of cross-linked peptide-RNA oligonucleotides derived from nonlabeled UV-irradiated ribonucleoprotein particles. RNA 2005 0.98
83 The heme a synthase Cox15 associates with cytochrome c oxidase assembly intermediates during Cox1 maturation. Mol Cell Biol 2013 0.97
84 The Methanothermobacter thermautotrophicus ExoIII homologue Mth212 is a DNA uridine endonuclease. Nucleic Acids Res 2006 0.96
85 Insights into the activation of the helicase Prp43 by biochemical studies and structural mass spectrometry. Nucleic Acids Res 2013 0.96
86 Identification of DEAD-box RNA helicase 6 (DDX6) as a cellular modulator of vascular endothelial growth factor expression under hypoxia. J Biol Chem 2013 0.96
87 In vivo localization and identification of SUMOylated proteins in the brain of His6-HA-SUMO1 knock-in mice. Proc Natl Acad Sci U S A 2012 0.95
88 Improved identification of enriched peptide RNA cross-links from ribonucleoprotein particles (RNPs) by mass spectrometry. Nucleic Acids Res 2007 0.95
89 Spatial interplay between PIASy and FIP200 in the regulation of signal transduction and transcriptional activity. Mol Cell Biol 2008 0.95
90 The archaeal Lsm protein binds to small RNAs. J Biol Chem 2010 0.94
91 Systematic identification of proteins binding to chromatin-embedded ubiquitylated H2B reveals recruitment of SWI/SNF to regulate transcription. Cell Rep 2013 0.94
92 Crystal structure of Cwc2 reveals a novel architecture of a multipartite RNA-binding protein. EMBO J 2012 0.94
93 The human Pat1b protein: a novel mRNA deadenylation factor identified by a new immunoprecipitation technique. Nucleic Acids Res 2010 0.94
94 The B-lymphoid Grb2 interaction code. Immunol Rev 2009 0.93
95 Multimerization and H3K9me3 binding are required for CDYL1b heterochromatin association. J Biol Chem 2009 0.93
96 Proteomic screening of glutamatergic mouse brain synaptosomes isolated by fluorescence activated sorting. EMBO J 2014 0.93
97 Evolution of the protein stoichiometry in the L12 stalk of bacterial and organellar ribosomes. Nat Commun 2013 0.92
98 Late motor decline after accomplished remyelination: impact for progressive multiple sclerosis. Ann Neurol 2012 0.92
99 β2 integrin-derived signals induce cell survival and proliferation of AML blasts by activating a Syk/STAT signaling axis. Blood 2013 0.92
100 Quantitative mass spectrometry-based proteomics: an overview. Methods Mol Biol 2012 0.92
101 The neuropeptidome of Rhodnius prolixus brain. Proteomics 2009 0.91
102 Two DEAD-box proteins may be part of RNA-dependent high-molecular-mass protein complexes in Arabidopsis mitochondria. Plant Physiol 2007 0.91
103 Structure of tripeptidyl-peptidase I provides insight into the molecular basis of late infantile neuronal ceroid lipofuscinosis. J Biol Chem 2008 0.90
104 The cytoplasmic peptidase DPP9 is rate-limiting for degradation of proline-containing peptides. J Biol Chem 2009 0.90
105 iTRAQ-labeling of in-gel digested proteins for relative quantification. Methods Mol Biol 2009 0.90
106 BC1-FMRP interaction is modulated by 2'-O-methylation: RNA-binding activity of the tudor domain and translational regulation at synapses. Nucleic Acids Res 2012 0.89
107 Burial of the polymorphic residue 129 in amyloid fibrils of prion stop mutants. J Biol Chem 2012 0.89
108 Synthesis and characterization of pseudocantharidins, novel phosphatase modulators that promote the inclusion of exon 7 into the SMN (survival of motoneuron) pre-mRNA. J Biol Chem 2011 0.89
109 Pabp binds to the osk 3'UTR and specifically contributes to osk mRNA stability and oocyte accumulation. Dev Biol 2011 0.88
110 An automated in-gel digestion/iTRAQ-labeling workflow for robust quantification of gel-separated proteins. Proteomics 2013 0.88
111 Complex phosphorylation dynamics control the composition of the Syk interactome in B cells. Eur J Immunol 2011 0.88
112 The NHL domain of BRAT is an RNA-binding domain that directly contacts the hunchback mRNA for regulation. Genes Dev 2014 0.88
113 Mitochondrial SIRT4-type proteins in Caenorhabditis elegans and mammals interact with pyruvate carboxylase and other acetylated biotin-dependent carboxylases. Mitochondrion 2013 0.87
114 Analysis of site-specific protein-RNA cross-links in isolated RNP complexes, combining affinity selection and mass spectrometry. RNA 2003 0.86
115 The zinc finger-associated domain of the Drosophila transcription factor grauzone is a novel zinc-coordinating protein-protein interaction module. Structure 2003 0.86
116 Investigation of protein-RNA interactions by mass spectrometry--Techniques and applications. J Proteomics 2012 0.86
117 A novel Nop5-sRNA interaction that is required for efficient archaeal box C/D sRNP formation. RNA 2010 0.85
118 Crystal structures of the antitermination factor NusB from Thermotoga maritima and implications for RNA binding. Biochem J 2004 0.85
119 SLP-65 phosphorylation dynamics reveals a functional basis for signal integration by receptor-proximal adaptor proteins. Mol Cell Proteomics 2009 0.85
120 Fc gamma receptor IIb modulates the molecular Grb2 interaction network in activated B cells. Cell Signal 2011 0.84
121 Mass spectrometry-based relative quantification of proteins in precatalytic and catalytically active spliceosomes by metabolic labeling (SILAC), chemical labeling (iTRAQ), and label-free spectral count. RNA 2014 0.84
122 SCFFbxw5 mediates transient degradation of actin remodeller Eps8 to allow proper mitotic progression. Nat Cell Biol 2013 0.84
123 An unusual mechanism of bacterial gene expression revealed for the RNase P protein of Thermus strains. Proc Natl Acad Sci U S A 2003 0.83
124 Phosphorylation site localization in peptides by MALDI MS/MS and the Mascot Delta Score. Anal Bioanal Chem 2011 0.83
125 Analysis of mammalian gene function using small interfering RNAs. Nucleic Acids Res Suppl 2003 0.83
126 Sequential phosphorylation of SLP-76 at tyrosine 173 is required for activation of T and mast cells. EMBO J 2011 0.82
127 Essential role of a trypanosome U4-specific Sm core protein in small nuclear ribonucleoprotein assembly and splicing. Eukaryot Cell 2010 0.82
128 Identification and characterization of FAM124B as a novel component of a CHD7 and CHD8 containing complex. PLoS One 2012 0.82
129 The human cytomegalovirus DNA polymerase processivity factor UL44 is modified by SUMO in a DNA-dependent manner. PLoS One 2012 0.82
130 Purification, crystallization and preliminary crystallographic data of the m3G cap-binding domain of human snRNP import factor snurportin 1. Acta Crystallogr D Biol Crystallogr 2004 0.82
131 Merging molecular electron microscopy and mass spectrometry by carbon film-assisted endoproteinase digestion. Mol Cell Proteomics 2010 0.82
132 Clathrin heavy chain plays multiple roles in polarizing the Drosophila oocyte downstream of Bic-D. Development 2014 0.82
133 Mass spectrometry imaging: linking molecule profiles to tissue spatial distribution. Expert Rev Proteomics 2013 0.81
134 Enrichment of protein-RNA crosslinks from crude UV-irradiated mixtures for MS analysis by on-line chromatography using titanium dioxide columns. Biopolymers 2009 0.81
135 SAP18 promotes Krüppel-dependent transcriptional repression by enhancer-specific histone deacetylation. J Biol Chem 2008 0.80
136 The claudin Megatrachea protein complex. J Biol Chem 2012 0.80
137 Mapping the binding site of snurportin 1 on native U1 snRNP by cross-linking and mass spectrometry. Nucleic Acids Res 2010 0.80
138 Structure and activity of the only human RNase T2. Nucleic Acids Res 2012 0.80
139 Biophysical properties and cellular toxicity of covalent crosslinked oligomers of α-synuclein formed by photoinduced side-chain tyrosyl radicals. Free Radic Biol Med 2012 0.79
140 Extraction of proteins from formalin-fixed, paraffin-embedded tissue using the Qproteome extraction technique and preparation of tryptic peptides for liquid chromatography/mass spectrometry analysis. Curr Protoc Mol Biol 2010 0.79
141 Absolute quantification of proteins using standard peptides and multiple reaction monitoring. Methods Mol Biol 2012 0.79
142 Biophysical and biochemical analysis of hnRNP K: arginine methylation, reversible aggregation and combinatorial binding to nucleic acids. Biol Chem 2014 0.79
143 Atmospheric pressure free liquid infrared MALDI mass spectrometry: toward a combined ESI/ MALDI-liquid chromatography interface. Anal Chem 2009 0.78
144 Increased proteome coverage by combining PAGE and peptide isoelectric focusing: comparative study of gel-based separation approaches. Proteomics 2013 0.78
145 Differential roles of postsynaptic density-93 isoforms in regulating synaptic transmission. J Neurosci 2013 0.78
146 Functional proteomics of neuropeptidome dynamics during the feeding process of Rhodnius prolixus. J Proteome Res 2011 0.78
147 Proteomic analysis of reaper 5' untranslated region-interacting factors isolated by tobramycin affinity-selection reveals a role for La antigen in reaper mRNA translation. Proteomics 2005 0.78
148 Separation methodology to improve proteome coverage depth. Expert Rev Proteomics 2014 0.78
149 OKB, a novel family of brain-gut neuropeptides from insects. Insect Biochem Mol Biol 2012 0.78
150 Cutting edge: feed-forward activation of phospholipase Cγ2 via C2 domain-mediated binding to SLP65. J Immunol 2013 0.78
151 The Dok-3/Grb2 protein signal module attenuates Lyn kinase-dependent activation of Syk kinase in B cell antigen receptor microclusters. J Biol Chem 2012 0.77
152 In vitro RNA editing in plant mitochondria does not require added energy. FEBS Lett 2007 0.77
153 Studying macromolecular complex stoichiometries by peptide-based mass spectrometry. Proteomics 2015 0.77
154 Mover is a homomeric phospho-protein present on synaptic vesicles. PLoS One 2013 0.77
155 Identification of endogenous SUMO1 accepter sites by mass spectrometry. Methods Mol Biol 2012 0.76
156 The SUMO1-E67 interacting loop peptide is an allosteric inhibitor of the dipeptidyl peptidases 8 and 9. J Biol Chem 2013 0.76
157 Pseudo-neutral-loss scan for selective detection of phosphopeptides and N-glycopeptides using liquid chromatography coupled with a hybrid linear ion-trap/orbitrap mass spectrometer. Proteomics 2010 0.76
158 Determinants of interaction specificity of the Bacillus subtilis GlcT antitermination protein: functionality and phosphorylation specificity depend on the arrangement of the regulatory domains. J Biol Chem 2012 0.76
159 Immunostimulatory activity of murine keratinocyte-derived exosomes. Exp Dermatol 2013 0.76
160 Initial insight into the function of the lysosomal 66.3 kDa protein from mouse by means of X-ray crystallography. BMC Struct Biol 2009 0.75
161 Structural analyses of the CRISPR protein Csc2 reveal the RNA-binding interface of the type I-D Cas7 family. RNA Biol 2014 0.75
162 'Proteomic basics--sample preparation and separation': the 1st European Summer School in Kloster Neustift, 12-18 August, 2007 Brixen/Bressanone, South Tyrol, Italy. Proteomics 2008 0.75
163 The guanine nucleotide exchange factor Vav2 is a negative regulator of parathyroid hormone receptor/Gq signaling. Mol Pharmacol 2012 0.75
164 Analyzing the protein assembly and dynamics of the human spliceosome with SILAC. Methods Mol Biol 2014 0.75
165 Correction: Nanobodies: site-specific labeling for super-resolution imaging, rapid epitope-mapping and native protein complex isolation. Elife 2016 0.75