Published in J Neurosci on January 06, 2010
Single-synapse analysis of a diverse synapse population: proteomic imaging methods and markers. Neuron (2010) 2.86
Presynaptic CLC-3 determines quantal size of inhibitory transmission in the hippocampus. Nat Neurosci (2011) 1.79
Neurotransmitter corelease: mechanism and physiological role. Annu Rev Physiol (2011) 1.52
Deep molecular diversity of mammalian synapses: why it matters and how to measure it. Nat Rev Neurosci (2012) 1.40
Vesicular and plasma membrane transporters for neurotransmitters. Cold Spring Harb Perspect Biol (2012) 1.02
Small GTPase Rab17 regulates dendritic morphogenesis and postsynaptic development of hippocampal neurons. J Biol Chem (2012) 0.98
An inside job: how endosomal Na(+)/H(+) exchangers link to autism and neurological disease. Front Cell Neurosci (2014) 0.96
Presynaptic regulation of quantal size: K+/H+ exchange stimulates vesicular glutamate transport. Nat Neurosci (2011) 0.96
A transcription factor network specifying inhibitory versus excitatory neurons in the dorsal spinal cord. Development (2014) 0.96
Proteomic screening of glutamatergic mouse brain synaptosomes isolated by fluorescence activated sorting. EMBO J (2014) 0.93
Lack of change in markers of presynaptic terminal abundance alongside subtle reductions in markers of presynaptic terminal plasticity in prefrontal cortex of schizophrenia patients. Biol Psychiatry (2011) 0.90
Sonic hedgehog regulates presynaptic terminal size, ultrastructure and function in hippocampal neurons. J Cell Sci (2012) 0.89
Levetiracetam reverses synaptic deficits produced by overexpression of SV2A. PLoS One (2011) 0.85
The role of non-canonical SNAREs in synaptic vesicle recycling. Cell Logist (2012) 0.85
Proteomics of the Synapse - A Quantitative Approach to Neuronal Plasticity. Mol Cell Proteomics (2015) 0.84
Analysis of Synaptotagmin, SV2, and Rab3 Expression in Cortical Glutamatergic and GABAergic Axon Terminals. Front Cell Neurosci (2012) 0.84
Presynaptic membrane retrieval and endosome biology: defining molecularly heterogeneous synaptic vesicles. Cold Spring Harb Perspect Biol (2013) 0.83
Involvement of ClC-3 chloride/proton exchangers in controlling glutamatergic synaptic strength in cultured hippocampal neurons. Front Cell Neurosci (2014) 0.82
Genotypic variation in the SV2C gene impacts response to atypical antipsychotics the CATIE study. Schizophr Res (2013) 0.81
Aberrant location of inhibitory synaptic marker proteins in the hippocampus of dystrophin-deficient mice: implications for cognitive impairment in duchenne muscular dystrophy. PLoS One (2014) 0.81
Interaction of PLP with GFP-MAL2 in the human oligodendroglial cell line HOG. PLoS One (2011) 0.81
Comparing development of synaptic proteins in rat visual, somatosensory, and frontal cortex. Front Neural Circuits (2013) 0.80
Isoflurane inhibits synaptic vesicle exocytosis through reduced Ca2+ influx, not Ca2+-exocytosis coupling. Proc Natl Acad Sci U S A (2015) 0.79
Proteomic analysis of the presynaptic active zone. Exp Brain Res (2012) 0.79
Activity-dependent adaptations in inhibitory axons. Front Cell Neurosci (2013) 0.78
BDNF enhances spontaneous and activity-dependent neurotransmitter release at excitatory terminals but not at inhibitory terminals in hippocampal neurons. Front Synaptic Neurosci (2014) 0.78
Functionally heterogeneous synaptic vesicle pools support diverse synaptic signalling. J Physiol (2015) 0.77
Sensory-Derived Glutamate Regulates Presynaptic Inhibitory Terminals in Mouse Spinal Cord. Neuron (2016) 0.76
Do we have to reconsider the evolutionary emergence of myelin? Front Cell Neurosci (2013) 0.76
Co-existence of Functionally Different Vesicular Neurotransmitter Transporters. Front Synaptic Neurosci (2016) 0.76
Synaptic Vesicle Glycoprotein 2A Ligands in the Treatment of Epilepsy and Beyond. CNS Drugs (2016) 0.76
Puzzling Out Synaptic Vesicle 2 Family Members Functions. Front Mol Neurosci (2017) 0.76
Towards the Molecular Foundations of Glutamatergic-targeted Antidepressants. Curr Neuropharmacol (2017) 0.75
The Proteome of the Murine Presynaptic Active Zone. Proteomes (2014) 0.75
Presynaptic Molecular Determinants of Quantal Size. Front Synaptic Neurosci (2016) 0.75
Unique pH dynamics in GABAergic synaptic vesicles illuminates the mechanism and kinetics of GABA loading. Proc Natl Acad Sci U S A (2016) 0.75
Self-propelling vesicles define glycolysis as the minimal energy machinery for neuronal transport. Nat Commun (2016) 0.75
Synaptic Interactome Mining Reveals p140Cap as a New Hub for PSD Proteins Involved in Psychiatric and Neurological Disorders. Front Mol Neurosci (2017) 0.75
Characteristics of 29 novel atypical solute carriers of major facilitator superfamily type: evolutionary conservation, predicted structure and neuronal co-expression. Open Biol (2017) 0.75
Single-stranded antisense siRNAs guide target RNA cleavage in RNAi. Cell (2002) 14.37
Molecular anatomy of a trafficking organelle. Cell (2006) 11.47
STED microscopy reveals that synaptotagmin remains clustered after synaptic vesicle exocytosis. Nature (2006) 6.54
Identification of novel argonaute-associated proteins. Curr Biol (2005) 6.13
Video-rate far-field optical nanoscopy dissects synaptic vesicle movement. Science (2008) 5.87
Proteomic and functional analysis of Argonaute-containing mRNA-protein complexes in human cells. EMBO Rep (2007) 3.89
Small nuclear ribonucleoprotein remodeling during catalytic activation of the spliceosome. Science (2002) 3.59
Molecular-level secondary structure, polymorphism, and dynamics of full-length alpha-synuclein fibrils studied by solid-state NMR. Proc Natl Acad Sci U S A (2005) 3.37
Protein composition of human prespliceosomes isolated by a tobramycin affinity-selection method. Proc Natl Acad Sci U S A (2002) 3.14
CASK Functions as a Mg2+-independent neurexin kinase. Cell (2008) 3.10
Isolation of an active step I spliceosome and composition of its RNP core. Nature (2008) 3.10
Macromolecular-scale resolution in biological fluorescence microscopy. Proc Natl Acad Sci U S A (2006) 3.04
Importin 8 is a gene silencing factor that targets argonaute proteins to distinct mRNAs. Cell (2009) 2.98
Helical extension of the neuronal SNARE complex into the membrane. Nature (2009) 2.92
N-methyl-D-aspartate receptor antibodies in herpes simplex encephalitis. Ann Neurol (2012) 2.91
A broken alpha -helix in folded alpha -Synuclein. J Biol Chem (2003) 2.80
GraFix: sample preparation for single-particle electron cryomicroscopy. Nat Methods (2007) 2.71
Synaptotagmin activates membrane fusion through a Ca2+-dependent trans interaction with phospholipids. Nat Struct Mol Biol (2007) 2.63
Protein composition and electron microscopy structure of affinity-purified human spliceosomal B complexes isolated under physiological conditions. Mol Cell Biol (2006) 2.55
Embryonic endocrine pancreas and mature beta cells acquire alpha and PP cell phenotypes upon Arx misexpression. J Clin Invest (2007) 2.46
EF-P is essential for rapid synthesis of proteins containing consecutive proline residues. Science (2012) 2.44
Two-color far-field fluorescence nanoscopy. Biophys J (2007) 2.44
SNARE assembly and disassembly exhibit a pronounced hysteresis. Nat Struct Biol (2002) 2.40
Membrane protein sequestering by ionic protein-lipid interactions. Nature (2011) 2.40
Characterization of novel SF3b and 17S U2 snRNP proteins, including a human Prp5p homologue and an SF3b DEAD-box protein. EMBO J (2002) 2.39
The evolutionarily conserved core design of the catalytic activation step of the yeast spliceosome. Mol Cell (2009) 2.39
Tuning of synapse number, structure and function in the cochlea. Nat Neurosci (2009) 2.29
Functional interaction between PML and SATB1 regulates chromatin-loop architecture and transcription of the MHC class I locus. Nat Cell Biol (2006) 2.29
Serotonylation of small GTPases is a signal transduction pathway that triggers platelet alpha-granule release. Cell (2003) 2.28
Determinants of liposome fusion mediated by synaptic SNARE proteins. Proc Natl Acad Sci U S A (2004) 2.28
Characterization of the Drosophila lipid droplet subproteome. Mol Cell Proteomics (2006) 2.23
A complete genetic analysis of neuronal Rab3 function. J Neurosci (2004) 2.21
Crystal structure of the endosomal SNARE complex reveals common structural principles of all SNAREs. Nat Struct Biol (2002) 2.21
A subset of human 35S U5 proteins, including Prp19, function prior to catalytic step 1 of splicing. EMBO J (2004) 2.20
Munc18-bound syntaxin readily forms SNARE complexes with synaptobrevin in native plasma membranes. PLoS Biol (2006) 2.17
Mechanism and consequences for paralog-specific sumoylation of ubiquitin-specific protease 25. Mol Cell (2008) 2.15
One SNARE complex is sufficient for membrane fusion. Nat Struct Mol Biol (2010) 2.14
Localization of the coactivator Cdh1 and the cullin subunit Apc2 in a cryo-electron microscopy model of vertebrate APC/C. Mol Cell (2005) 2.09
Pre-fibrillar alpha-synuclein variants with impaired beta-structure increase neurotoxicity in Parkinson's disease models. EMBO J (2009) 2.09
Composition and three-dimensional EM structure of double affinity-purified, human prespliceosomal A complexes. EMBO J (2007) 2.07
Synaptotagmin-1 docks secretory vesicles to syntaxin-1/SNAP-25 acceptor complexes. Cell (2009) 2.06
Identification, cloning, and functional analysis of the human U6 snRNA-specific terminal uridylyl transferase. RNA (2006) 2.05
Imaging direct, dynamin-dependent recapture of fusing secretory granules on plasma membrane lawns from PC12 cells. Proc Natl Acad Sci U S A (2002) 2.03
Atomic model of the type III secretion system needle. Nature (2012) 2.02
Regulation of monoamine oxidase A by circadian-clock components implies clock influence on mood. Curr Biol (2008) 1.97
Bassoon and the synaptic ribbon organize Ca²+ channels and vesicles to add release sites and promote refilling. Neuron (2010) 1.95
Assembly and maturation of the U3 snoRNP in the nucleoplasm in a large dynamic multiprotein complex. Mol Cell (2004) 1.89
Reconstitution of both steps of Saccharomyces cerevisiae splicing with purified spliceosomal components. Nat Struct Mol Biol (2009) 1.89
Exon definition complexes contain the tri-snRNP and can be directly converted into B-like precatalytic splicing complexes. Mol Cell (2010) 1.84
Protein composition of human mRNPs spliced in vitro and differential requirements for mRNP protein recruitment. RNA (2006) 1.83
Storage and uptake of D-serine into astrocytic synaptic-like vesicles specify gliotransmission. J Neurosci (2013) 1.82
Hierarchical, clustered protein interactions with U4/U6 snRNA: a biochemical role for U4/U6 proteins. EMBO J (2002) 1.82
A cytoplasmic complex mediates specific mRNA recognition and localization in yeast. PLoS Biol (2011) 1.78
A reversibly photoswitchable GFP-like protein with fluorescence excitation decoupled from switching. Nat Biotechnol (2011) 1.74
Phosphorylation of human PRP28 by SRPK2 is required for integration of the U4/U6-U5 tri-snRNP into the spliceosome. Nat Struct Mol Biol (2008) 1.73
Membrane fusion intermediates via directional and full assembly of the SNARE complex. Science (2012) 1.71
Plasmalemmal phosphatidylinositol-4,5-bisphosphate level regulates the releasable vesicle pool size in chromaffin cells. J Neurosci (2005) 1.71
The human 18S U11/U12 snRNP contains a set of novel proteins not found in the U2-dependent spliceosome. RNA (2004) 1.67
SNAREs prefer liquid-disordered over "raft" (liquid-ordered) domains when reconstituted into giant unilamellar vesicles. J Biol Chem (2004) 1.65
Conservation of the protein composition and electron microscopy structure of Drosophila melanogaster and human spliceosomal complexes. Mol Cell Biol (2008) 1.64
The claudin-like megatrachea is essential in septate junctions for the epithelial barrier function in Drosophila. Dev Cell (2003) 1.64
Phosphorylation of human Argonaute proteins affects small RNA binding. Nucleic Acids Res (2010) 1.64
Rapid and selective binding to the synaptic SNARE complex suggests a modulatory role of complexins in neuroexocytosis. J Biol Chem (2001) 1.63
Syk kinase-coupled C-type lectin receptors engage protein kinase C-σ to elicit Card9 adaptor-mediated innate immunity. Immunity (2012) 1.61
Homotypic fusion of early endosomes: SNAREs do not determine fusion specificity. Proc Natl Acad Sci U S A (2006) 1.59
The nuclear F-actin interactome of Xenopus oocytes reveals an actin-bundling kinesin that is essential for meiotic cytokinesis. EMBO J (2013) 1.58
Dynamic structure of lipid-bound synaptobrevin suggests a nucleation-propagation mechanism for trans-SNARE complex formation. Proc Natl Acad Sci U S A (2009) 1.57
Localization versus function of Rab3 proteins. Evidence for a common regulatory role in controlling fusion. J Biol Chem (2002) 1.56
B cell receptor-mediated antigen gathering requires ubiquitin ligase Cbl and adaptors Grb2 and Dok-3 to recruit dynein to the signaling microcluster. Immunity (2011) 1.53
Dissociation of amyloid fibrils of alpha-synuclein in supercooled water. Angew Chem Int Ed Engl (2008) 1.51
The riddle of the Sec1/Munc-18 proteins - new twists added to their interactions with SNAREs. Trends Biochem Sci (2003) 1.50
Hearing requires otoferlin-dependent efficient replenishment of synaptic vesicles in hair cells. Nat Neurosci (2010) 1.48
Semiquantitative proteomic analysis of the human spliceosome via a novel two-dimensional gel electrophoresis method. Mol Cell Biol (2011) 1.48
SNAREs in native plasma membranes are active and readily form core complexes with endogenous and exogenous SNAREs. J Cell Biol (2002) 1.45
Molecular architecture of the human Prp19/CDC5L complex. Mol Cell Biol (2010) 1.44
Detecting endogenous SUMO targets in mammalian cells and tissues. Nat Struct Mol Biol (2013) 1.44
Botulinum neurotoxins C, E and F bind gangliosides via a conserved binding site prior to stimulation-dependent uptake with botulinum neurotoxin F utilising the three isoforms of SV2 as second receptor. J Neurochem (2009) 1.44
Synaptotagmin-1 may be a distance regulator acting upstream of SNARE nucleation. Nat Struct Mol Biol (2011) 1.41
Characterization of the cleavage site and function of resulting cleavage fragments after limited proteolysis of Clostridium difficile toxin B (TcdB) by host cells. Microbiology (2005) 1.40
Phosphatidylinositol 4,5-bisphosphate clusters act as molecular beacons for vesicle recruitment. Nat Struct Mol Biol (2013) 1.38
The R-SNARE motif of tomosyn forms SNARE core complexes with syntaxin 1 and SNAP-25 and down-regulates exocytosis. J Biol Chem (2003) 1.38
The Ca2+ affinity of synaptotagmin 1 is markedly increased by a specific interaction of its C2B domain with phosphatidylinositol 4,5-bisphosphate. J Biol Chem (2009) 1.38
Structural and functional analysis of the E. coli NusB-S10 transcription antitermination complex. Mol Cell (2008) 1.37
MINOS1 is a conserved component of mitofilin complexes and required for mitochondrial function and cristae organization. Mol Biol Cell (2011) 1.37
Discrimination between docking and fusion of liposomes reconstituted with neuronal SNARE-proteins using FCS. Proc Natl Acad Sci U S A (2009) 1.36
Post-transcriptional spliceosomes are retained in nuclear speckles until splicing completion. Nat Commun (2012) 1.35
Molecular cloning and functional characterization of human vesicular glutamate transporter 3. EMBO Rep (2002) 1.35
Anle138b: a novel oligomer modulator for disease-modifying therapy of neurodegenerative diseases such as prion and Parkinson's disease. Acta Neuropathol (2013) 1.34
Probing the mechanism of exocytosis at the hair cell ribbon synapse. J Neurosci (2007) 1.33