Published in J Am Chem Soc on October 04, 2008
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Transpeptidase-mediated incorporation of D-amino acids into bacterial peptidoglycan. J Am Chem Soc (2011) 1.37
Forming cross-linked peptidoglycan from synthetic gram-negative Lipid II. J Am Chem Soc (2013) 1.18
Moenomycin family antibiotics: chemical synthesis, biosynthesis, and biological activity. Nat Prod Rep (2010) 1.15
The role of the substrate lipid in processive glycan polymerization by the peptidoglycan glycosyltransferases. J Am Chem Soc (2010) 1.11
A tethering mechanism for length control in a processive carbohydrate polymerization. Proc Natl Acad Sci U S A (2009) 1.10
Lipoprotein activators stimulate Escherichia coli penicillin-binding proteins by different mechanisms. J Am Chem Soc (2013) 1.10
Studying a cell division amidase using defined peptidoglycan substrates. J Am Chem Soc (2009) 0.91
Monitoring processivity and length control of a carbohydrate polymerase. J Am Chem Soc (2011) 0.91
Identification of MltG as a potential terminase for peptidoglycan polymerization in bacteria. Mol Microbiol (2015) 0.89
The molecular origins of chiral growth in walled cells. Curr Opin Microbiol (2012) 0.87
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N-methylimidazolium chloride-catalyzed pyrophosphate formation: application to the synthesis of Lipid I and NDP-sugar donors. Bioorg Med Chem Lett (2011) 0.87
Tuning the moenomycin pharmacophore to enable discovery of bacterial cell wall synthesis inhibitors. J Am Chem Soc (2013) 0.85
Moenomycin resistance mutations in Staphylococcus aureus reduce peptidoglycan chain length and cause aberrant cell division. ACS Chem Biol (2013) 0.84
Host-guest chemistry of the peptidoglycan. J Med Chem (2010) 0.82
Coarse-grained simulations of bacterial cell wall growth reveal that local coordination alone can be sufficient to maintain rod shape. Proc Natl Acad Sci U S A (2015) 0.78
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Comparing Galactan Biosynthesis in Mycobacterium tuberculosis and Corynebacterium diphtheriae. J Biol Chem (2016) 0.75
Contrasting mechanisms of growth in two model rod-shaped bacteria. Nat Commun (2017) 0.75
Peptidoglycan structure and architecture. FEMS Microbiol Rev (2008) 6.69
The penicillin-binding proteins: structure and role in peptidoglycan biosynthesis. FEMS Microbiol Rev (2008) 4.83
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Bacterial cell wall synthesis: new insights from localization studies. Microbiol Mol Biol Rev (2005) 3.72
Three-dimensional structure of the bacterial cell wall peptidoglycan. Proc Natl Acad Sci U S A (2006) 2.81
Murein (peptidoglycan) structure, architecture and biosynthesis in Escherichia coli. Biochim Biophys Acta (2007) 2.72
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Hyaluronan synthases: a decade-plus of novel glycosyltransferases. J Biol Chem (2007) 2.05
The architecture of the murein (peptidoglycan) in gram-negative bacteria: vertical scaffold or horizontal layer(s)? J Bacteriol (2004) 1.99
Vancomycin analogues active against vanA-resistant strains inhibit bacterial transglycosylase without binding substrate. Proc Natl Acad Sci U S A (2003) 1.96
Quantitative determination of N-acetylglucosamine residues at the non-reducing ends of peptidoglycan chains by enzymic attachment of [14C]-D-galactose. Eur J Biochem (1976) 1.83
Towards a comprehensive view of the bacterial cell wall. Trends Microbiol (2005) 1.82
Isolation and separation of the glycan strands from murein of Escherichia coli by reversed-phase high-performance liquid chromatography. Anal Biochem (1990) 1.78
Crystal structure of a peptidoglycan glycosyltransferase suggests a model for processive glycan chain synthesis. Proc Natl Acad Sci U S A (2007) 1.68
Role of penicillin-binding proteins in bacterial cell morphogenesis. Curr Opin Microbiol (2003) 1.66
Tertiary structure of bacterial murein: the scaffold model. J Bacteriol (2003) 1.47
Nontemplate-dependent polymerization processes: polyhydroxyalkanoate synthases as a paradigm. Annu Rev Biochem (2005) 1.45
A kinetic characterization of the glycosyltransferase activity of Eschericia coli PBP1b and development of a continuous fluorescence assay. Biochemistry (2002) 1.43
Kinetic characterization of the glycosyltransferase module of Staphylococcus aureus PBP2. J Bacteriol (2005) 1.41
Analysis of glycan polymers produced by peptidoglycan glycosyltransferases. J Biol Chem (2007) 1.36
Synthesis of heptaprenyl-lipid IV to analyze peptidoglycan glycosyltransferases. J Am Chem Soc (2007) 1.35
Degradation and reconstruction of moenomycin A and derivatives: dissecting the function of the isoprenoid chain. J Am Chem Soc (2006) 1.14
Too many strictures on structure. Trends Microbiol (2006) 0.83
Characterization of a transglycosylase domain of Streptococcus pneumoniae PBP1b. Bioorg Med Chem (2006) 0.80
Identification of a multicomponent complex required for outer membrane biogenesis in Escherichia coli. Cell (2005) 8.22
The bacterial cell envelope. Cold Spring Harb Perspect Biol (2010) 5.14
Structure and function of an essential component of the outer membrane protein assembly machine. Science (2007) 3.85
Reconstitution of outer membrane protein assembly from purified components. Science (2010) 3.30
Defining the roles of the periplasmic chaperones SurA, Skp, and DegP in Escherichia coli. Genes Dev (2007) 3.24
Advances in understanding bacterial outer-membrane biogenesis. Nat Rev Microbiol (2006) 3.23
Chemical conditionality: a genetic strategy to probe organelle assembly. Cell (2005) 3.12
Lipoprotein SmpA is a component of the YaeT complex that assembles outer membrane proteins in Escherichia coli. Proc Natl Acad Sci U S A (2007) 3.09
Identification of a protein complex that assembles lipopolysaccharide in the outer membrane of Escherichia coli. Proc Natl Acad Sci U S A (2006) 2.87
YfiO stabilizes the YaeT complex and is essential for outer membrane protein assembly in Escherichia coli. Mol Microbiol (2006) 2.84
β-Barrel membrane protein assembly by the Bam complex. Annu Rev Biochem (2011) 2.55
Lipoprotein cofactors located in the outer membrane activate bacterial cell wall polymerases. Cell (2010) 2.53
Imaging peptidoglycan biosynthesis in Bacillus subtilis with fluorescent antibiotics. Proc Natl Acad Sci U S A (2006) 2.53
Discovery of O-GlcNAc transferase inhibitors. J Am Chem Soc (2005) 2.27
Lipid II is an intrinsic component of the pore induced by nisin in bacterial membranes. J Biol Chem (2003) 2.26
Structure of human O-GlcNAc transferase and its complex with a peptide substrate. Nature (2011) 2.24
Identification of two inner-membrane proteins required for the transport of lipopolysaccharide to the outer membrane of Escherichia coli. Proc Natl Acad Sci U S A (2008) 2.21
Wall teichoic acid function, biosynthesis, and inhibition. Chembiochem (2010) 2.15
Transport of lipopolysaccharide across the cell envelope: the long road of discovery. Nat Rev Microbiol (2009) 2.07
Crystal structure of the MurG:UDP-GlcNAc complex reveals common structural principles of a superfamily of glycosyltransferases. Proc Natl Acad Sci U S A (2003) 2.02
Vancomycin analogues active against vanA-resistant strains inhibit bacterial transglycosylase without binding substrate. Proc Natl Acad Sci U S A (2003) 1.96
Regulation of cell size in response to nutrient availability by fatty acid biosynthesis in Escherichia coli. Proc Natl Acad Sci U S A (2012) 1.91
Incorporation of glucose analogs by GtfE and GtfD from the vancomycin biosynthetic pathway to generate variant glycopeptides. Chem Biol (2002) 1.90
In vitro reconstitution of two essential steps in wall teichoic acid biosynthesis. ACS Chem Biol (2006) 1.89
Probing the barrier function of the outer membrane with chemical conditionality. ACS Chem Biol (2006) 1.86
Characterization of the two-protein complex in Escherichia coli responsible for lipopolysaccharide assembly at the outer membrane. Proc Natl Acad Sci U S A (2010) 1.85
Wall teichoic acids of gram-positive bacteria. Annu Rev Microbiol (2013) 1.77
Crystal structure of a peptidoglycan glycosyltransferase suggests a model for processive glycan chain synthesis. Proc Natl Acad Sci U S A (2007) 1.68
The complex that inserts lipopolysaccharide into the bacterial outer membrane forms a two-protein plug-and-barrel. Proc Natl Acad Sci U S A (2011) 1.68
Synthetic lethal compound combinations reveal a fundamental connection between wall teichoic acid and peptidoglycan biosyntheses in Staphylococcus aureus. ACS Chem Biol (2010) 1.64
Remarkable structural similarities between diverse glycosyltransferases. Chem Biol (2002) 1.56
Proteins required for lipopolysaccharide assembly in Escherichia coli form a transenvelope complex. Biochemistry (2010) 1.54
A revised pathway proposed for Staphylococcus aureus wall teichoic acid biosynthesis based on in vitro reconstitution of the intracellular steps. Chem Biol (2008) 1.52
Bacterial transglycosylase inhibitors. Curr Opin Chem Biol (2005) 1.51
Nonconsecutive disulfide bond formation in an essential integral outer membrane protein. Proc Natl Acad Sci U S A (2010) 1.48
A streamlined metabolic pathway for the biosynthesis of moenomycin A. Chem Biol (2007) 1.47
Intrinsic lipid preferences and kinetic mechanism of Escherichia coli MurG. Biochemistry (2002) 1.44
Lipoprotein LptE is required for the assembly of LptD by the beta-barrel assembly machine in the outer membrane of Escherichia coli. Proc Natl Acad Sci U S A (2011) 1.41
Kinetic characterization of the glycosyltransferase module of Staphylococcus aureus PBP2. J Bacteriol (2005) 1.41
Methicillin resistance in Staphylococcus aureus requires glycosylated wall teichoic acids. Proc Natl Acad Sci U S A (2012) 1.39
Distinct single-cell morphological dynamics under beta-lactam antibiotics. Mol Cell (2012) 1.39
Cytoplasmic ATP hydrolysis powers transport of lipopolysaccharide across the periplasm in E. coli. Science (2012) 1.37
Discovery of a small molecule that blocks wall teichoic acid biosynthesis in Staphylococcus aureus. ACS Chem Biol (2009) 1.37
Transpeptidase-mediated incorporation of D-amino acids into bacterial peptidoglycan. J Am Chem Soc (2011) 1.37
Analysis of glycan polymers produced by peptidoglycan glycosyltransferases. J Biol Chem (2007) 1.36
Synthesis of heptaprenyl-lipid IV to analyze peptidoglycan glycosyltransferases. J Am Chem Soc (2007) 1.35
Regulated assembly of the transenvelope protein complex required for lipopolysaccharide export. Biochemistry (2012) 1.35
Cutaneous metastases in breast cancer. Clin J Oncol Nurs (2011) 1.30
Rapid beta-lactam-induced lysis requires successful assembly of the cell division machinery. Proc Natl Acad Sci U S A (2009) 1.29
The direction of glycan chain elongation by peptidoglycan glycosyltransferases. J Am Chem Soc (2007) 1.28
Ramoplanin inhibits bacterial transglycosylases by binding as a dimer to lipid II. J Am Chem Soc (2003) 1.24
Differential inhibition of Staphylococcus aureus PBP2 by glycopeptide antibiotics. J Am Chem Soc (2005) 1.23
Late-stage polyribitol phosphate wall teichoic acid biosynthesis in Staphylococcus aureus. J Bacteriol (2008) 1.22
HCF-1 is cleaved in the active site of O-GlcNAc transferase. Science (2013) 1.21
The mechanism of action of ramoplanin and enduracidin. Mol Biosyst (2005) 1.21
Identification of active-site inhibitors of MurG using a generalizable, high-throughput glycosyltransferase screen. J Am Chem Soc (2003) 1.20
Structural snapshots of the reaction coordinate for O-GlcNAc transferase. Nat Chem Biol (2012) 1.20
Complete characterization of the seventeen step moenomycin biosynthetic pathway. Biochemistry (2009) 1.19
Structural analysis of the contacts anchoring moenomycin to peptidoglycan glycosyltransferases and implications for antibiotic design. ACS Chem Biol (2008) 1.19
Forming cross-linked peptidoglycan from synthetic gram-negative Lipid II. J Am Chem Soc (2013) 1.18
AknT is an activating protein for the glycosyltransferase AknS in L-aminodeoxysugar transfer to the aglycone of aclacinomycin A. Chem Biol (2005) 1.18
Expression and characterization of the isolated glycosyltransferase module of Escherichia coli PBP1b. Biochemistry (2004) 1.17
The reconstituted Escherichia coli Bam complex catalyzes multiple rounds of β-barrel assembly. Biochemistry (2011) 1.17
D-amino acids indirectly inhibit biofilm formation in Bacillus subtilis by interfering with protein synthesis. J Bacteriol (2013) 1.15
The structural basis for induction of VanB resistance. J Am Chem Soc (2002) 1.15
Moenomycin family antibiotics: chemical synthesis, biosynthesis, and biological activity. Nat Prod Rep (2010) 1.15
In vitro reconstitution of EryCIII activity for the preparation of unnatural macrolides. J Am Chem Soc (2005) 1.13
Activation of the Escherichia coli β-barrel assembly machine (Bam) is required for essential components to interact properly with substrate. Proc Natl Acad Sci U S A (2012) 1.12
Disulfide rearrangement triggered by translocon assembly controls lipopolysaccharide export. Science (2012) 1.11
The role of the substrate lipid in processive glycan polymerization by the peptidoglycan glycosyltransferases. J Am Chem Soc (2010) 1.11
Lipoprotein activators stimulate Escherichia coli penicillin-binding proteins by different mechanisms. J Am Chem Soc (2013) 1.10
The Escherichia coli Lpt transenvelope protein complex for lipopolysaccharide export is assembled via conserved structurally homologous domains. J Bacteriol (2013) 1.08
Discovery of wall teichoic acid inhibitors as potential anti-MRSA β-lactam combination agents. Chem Biol (2013) 1.07
Acceptor substrate selectivity and kinetic mechanism of Bacillus subtilis TagA. Biochemistry (2006) 1.06
A systematic investigation of the synthetic utility of glycopeptide glycosyltransferases. J Am Chem Soc (2005) 1.05
Comparison of antigen constructs and carrier molecules for augmenting the immunogenicity of the monosaccharide epithelial cancer antigen Tn. Cancer Immunol Immunother (2004) 1.05
Coordination of export and glycosylation of landomycins in Streptomyces cyanogenus S136. FEMS Microbiol Lett (2008) 1.05
On the essentiality of lipopolysaccharide to Gram-negative bacteria. Curr Opin Microbiol (2013) 1.04
Nine enzymes are required for assembly of the pacidamycin group of peptidyl nucleoside antibiotics. J Am Chem Soc (2011) 1.04
O-linked N-acetylglucosaminyltransferase inhibition prevents G2/M transition in Xenopus laevis oocytes. J Biol Chem (2007) 1.04
Use of a retroinverso p53 peptide as an inhibitor of MDM2. J Am Chem Soc (2004) 1.03
Stochastic detection of monovalent and bivalent protein-ligand interactions. Angew Chem Int Ed Engl (2004) 1.02
Identification of selective inhibitors for the glycosyltransferase MurG via high-throughput screening. Chem Biol (2004) 1.02
A neutral diphosphate mimic crosslinks the active site of human O-GlcNAc transferase. Nat Chem Biol (2011) 1.02
Rethinking ramoplanin: the role of substrate binding in inhibition of peptidoglycan biosynthesis. J Am Chem Soc (2002) 1.01
Genetic factors that influence moenomycin production in streptomycetes. J Ind Microbiol Biotechnol (2010) 1.00