PubRank

Carl G Figdor

Author PubWeight™ 196.70‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Magnetic resonance tracking of dendritic cells in melanoma patients for monitoring of cellular therapy. Nat Biotechnol 2005 5.80
2 Physical limits of cell migration: control by ECM space and nuclear deformation and tuning by proteolysis and traction force. J Cell Biol 2013 3.77
3 The dendritic cell-specific adhesion receptor DC-SIGN internalizes antigen for presentation to T cells. J Immunol 2002 3.48
4 Dendritic-cell immunotherapy: from ex vivo loading to in vivo targeting. Nat Rev Immunol 2007 3.42
5 Different faces of the heme-heme oxygenase system in inflammation. Pharmacol Rev 2003 2.52
6 Effective migration of antigen-pulsed dendritic cells to lymph nodes in melanoma patients is determined by their maturation state. Cancer Res 2003 2.32
7 The C-type lectin DC-SIGN (CD209) is an antigen-uptake receptor for Candida albicans on dendritic cells. Eur J Immunol 2003 2.30
8 TRPM7, a novel regulator of actomyosin contractility and cell adhesion. EMBO J 2006 2.20
9 Targeting CD4(+) T-helper cells improves the induction of antitumor responses in dendritic cell-based vaccination. Cancer Res 2012 2.08
10 In situ tumor ablation creates an antigen source for the generation of antitumor immunity. Cancer Res 2004 2.06
11 Platinum-based drugs disrupt STAT6-mediated suppression of immune responses against cancer in humans and mice. J Clin Invest 2011 1.91
12 Myosin II and mechanotransduction: a balancing act. Trends Cell Biol 2007 1.85
13 Targeted delivery of TLR ligands to human and mouse dendritic cells strongly enhances adjuvanticity. Blood 2011 1.83
14 Targeting DCIR on human plasmacytoid dendritic cells results in antigen presentation and inhibits IFN-alpha production. Blood 2008 1.79
15 How C-type lectins detect pathogens. Cell Microbiol 2005 1.77
16 Identification of different binding sites in the dendritic cell-specific receptor DC-SIGN for intercellular adhesion molecule 3 and HIV-1. J Biol Chem 2002 1.71
17 Toll-like receptor expression and function in human dendritic cell subsets: implications for dendritic cell-based anti-cancer immunotherapy. Cancer Immunol Immunother 2010 1.60
18 Consolidative dendritic cell-based immunotherapy elicits cytotoxicity against malignant mesothelioma. Am J Respir Crit Care Med 2010 1.60
19 Hotspots of GPI-anchored proteins and integrin nanoclusters function as nucleation sites for cell adhesion. Proc Natl Acad Sci U S A 2009 1.60
20 Effective induction of naive and recall T-cell responses by targeting antigen to human dendritic cells via a humanized anti-DC-SIGN antibody. Blood 2005 1.57
21 Maturation of dendritic cells is a prerequisite for inducing immune responses in advanced melanoma patients. Clin Cancer Res 2003 1.57
22 Dual function of C-type lectin-like receptors in the immune system. Curr Opin Cell Biol 2003 1.53
23 Dendritic cell interaction with Candida albicans critically depends on N-linked mannan. J Biol Chem 2008 1.50
24 (19)F MRI for quantitative in vivo cell tracking. Trends Biotechnol 2010 1.49
25 Immunomonitoring tumor-specific T cells in delayed-type hypersensitivity skin biopsies after dendritic cell vaccination correlates with clinical outcome. J Clin Oncol 2005 1.48
26 Microdomains of the C-type lectin DC-SIGN are portals for virus entry into dendritic cells. J Cell Biol 2004 1.48
27 Dendritic cell vaccination in combination with anti-CD25 monoclonal antibody treatment: a phase I/II study in metastatic melanoma patients. Clin Cancer Res 2010 1.45
28 Sensitivity of magnetic resonance imaging of dendritic cells for in vivo tracking of cellular cancer vaccines. Int J Cancer 2007 1.42
29 Peptide fine specificity of anti-glycoprotein 100 CTL is preserved following transfer of engineered TCR alpha beta genes into primary human T lymphocytes. J Immunol 2003 1.41
30 The heme-heme oxygenase system: a molecular switch in wound healing. Blood 2003 1.39
31 The small GTPase Rap1 is required for Mn(2+)- and antibody-induced LFA-1- and VLA-4-mediated cell adhesion. J Biol Chem 2002 1.39
32 A critical role for prostaglandin E2 in podosome dissolution and induction of high-speed migration during dendritic cell maturation. J Immunol 2006 1.37
33 Natural human plasmacytoid dendritic cells induce antigen-specific T-cell responses in melanoma patients. Cancer Res 2013 1.35
34 Regulatory T cells in melanoma: the final hurdle towards effective immunotherapy? Lancet Oncol 2012 1.34
35 The C-type lectin receptor CLEC9A mediates antigen uptake and (cross-)presentation by human blood BDCA3+ myeloid dendritic cells. Blood 2012 1.34
36 TRPM7 regulates myosin IIA filament stability and protein localization by heavy chain phosphorylation. J Mol Biol 2008 1.32
37 Targeted PLGA nano- but not microparticles specifically deliver antigen to human dendritic cells via DC-SIGN in vitro. J Control Release 2010 1.32
38 Long-term engagement of CD6 and ALCAM is essential for T-cell proliferation induced by dendritic cells. Blood 2005 1.30
39 Elevated CXCL16 expression by synovial macrophages recruits memory T cells into rheumatoid joints. Arthritis Rheum 2005 1.29
40 Route of administration modulates the induction of dendritic cell vaccine-induced antigen-specific T cells in advanced melanoma patients. Clin Cancer Res 2011 1.29
41 Organization of the integrin LFA-1 in nanoclusters regulates its activity. Mol Biol Cell 2006 1.26
42 Synergy between in situ cryoablation and TLR9 stimulation results in a highly effective in vivo dendritic cell vaccine. Cancer Res 2006 1.26
43 Ovarian cancer creates a suppressive microenvironment to escape immune elimination. Gynecol Oncol 2010 1.24
44 Limited amounts of dendritic cells migrate into the T-cell area of lymph nodes but have high immune activating potential in melanoma patients. Clin Cancer Res 2009 1.24
45 Human plasmacytoid dendritic cells are equipped with antigen-presenting and tumoricidal capacities. Blood 2012 1.23
46 DCIR is endocytosed into human dendritic cells and inhibits TLR8-mediated cytokine production. J Leukoc Biol 2008 1.22
47 Human plasmacytoid dendritic cells efficiently cross-present exogenous Ags to CD8+ T cells despite lower Ag uptake than myeloid dendritic cell subsets. Blood 2012 1.21
48 Massive autophosphorylation of the Ser/Thr-rich domain controls protein kinase activity of TRPM6 and TRPM7. PLoS One 2008 1.19
49 Early identification of antigen-specific immune responses in vivo by [18F]-labeled 3'-fluoro-3'-deoxy-thymidine ([18F]FLT) PET imaging. Proc Natl Acad Sci U S A 2011 1.19
50 PGE2-mediated podosome loss in dendritic cells is dependent on actomyosin contraction downstream of the RhoA-Rho-kinase axis. J Cell Sci 2008 1.18
51 Customizable, multi-functional fluorocarbon nanoparticles for quantitative in vivo imaging using 19F MRI and optical imaging. Biomaterials 2010 1.18
52 Maturation of monocyte-derived dendritic cells with Toll-like receptor 3 and 7/8 ligands combined with prostaglandin E2 results in high interleukin-12 production and cell migration. Cancer Immunol Immunother 2008 1.15
53 Lateral mobility of individual integrin nanoclusters orchestrates the onset for leukocyte adhesion. Proc Natl Acad Sci U S A 2012 1.15
54 Functional differences between mesenchymal stem cell populations are reflected by their transcriptome. Stem Cells Dev 2010 1.14
55 Phenotypical and functional characterization of clinical grade dendritic cells. J Immunother 2002 1.12
56 Vaccination with mRNA-electroporated dendritic cells induces robust tumor antigen-specific CD4+ and CD8+ T cells responses in stage III and IV melanoma patients. Clin Cancer Res 2012 1.11
57 Migration of dendritic cell based cancer vaccines: in vivo veritas? Curr Opin Immunol 2005 1.11
58 Maximizing dendritic cell migration in cancer immunotherapy. Expert Opin Biol Ther 2008 1.11
59 Nanoscale organization of the pathogen receptor DC-SIGN mapped by single-molecule high-resolution fluorescence microscopy. Chemphyschem 2007 1.10
60 Ligand-conjugated quantum dots monitor antigen uptake and processing by dendritic cells. Nano Lett 2007 1.10
61 Targeting uptake receptors on human plasmacytoid dendritic cells triggers antigen cross-presentation and robust type I IFN secretion. J Immunol 2013 1.09
62 The dendritic cell-derived protein DC-STAMP is highly conserved and localizes to the endoplasmic reticulum. J Leukoc Biol 2004 1.09
63 Dectin-1 interaction with tetraspanin CD37 inhibits IL-6 production. J Immunol 2007 1.08
64 Interlaboratory round robin on cantilever calibration for AFM force spectroscopy. Ultramicroscopy 2011 1.08
65 Route of administration of the TLR9 agonist CpG critically determines the efficacy of cancer immunotherapy in mice. PLoS One 2009 1.07
66 Commonly used prophylactic vaccines as an alternative for synthetically produced TLR ligands to mature monocyte-derived dendritic cells. Blood 2010 1.07
67 The alpha-kinases TRPM6 and TRPM7, but not eEF-2 kinase, phosphorylate the assembly domain of myosin IIA, IIB and IIC. FEBS Lett 2008 1.07
68 Targeted antigen delivery and activation of dendritic cells in vivo: steps towards cost effective vaccines. Semin Immunol 2011 1.06
69 Targeting DC-SIGN via its neck region leads to prolonged antigen residence in early endosomes, delayed lysosomal degradation, and cross-presentation. Blood 2011 1.06
70 The tetraspanin protein CD37 regulates IgA responses and anti-fungal immunity. PLoS Pathog 2009 1.05
71 Targeting dendritic cells--why bother? Blood 2013 1.04
72 Expression of the dendritic cell-associated C-type lectin DC-SIGN by inflammatory matrix metalloproteinase-producing macrophages in rheumatoid arthritis synovium and interaction with intercellular adhesion molecule 3-positive T cells. Arthritis Rheum 2003 1.04
73 Labeling cells for in vivo tracking using (19)F MRI. Biomaterials 2012 1.04
74 Wild-type and modified gp100 peptide-pulsed dendritic cell vaccination of advanced melanoma patients can lead to long-term clinical responses independent of the peptide used. Cancer Immunol Immunother 2010 1.04
75 Plasmacytoid dendritic cells of melanoma patients present exogenous proteins to CD4+ T cells after Fc gamma RII-mediated uptake. J Exp Med 2006 1.03
76 Skin-test infiltrating lymphocytes early predict clinical outcome of dendritic cell-based vaccination in metastatic melanoma. Cancer Res 2012 1.03
77 Immune adjuvant efficacy of CpG oligonucleotide in cancer treatment is founded specifically upon TLR9 function in plasmacytoid dendritic cells. Cancer Res 2011 1.03
78 Cytokine analysis as a tool to understand tumour-host interaction in ovarian cancer. Eur J Cancer 2011 1.03
79 Targeting antigens to dendritic cells in vivo. Immunobiology 2006 1.02
80 In situ expression of tumor antigens by messenger RNA-electroporated dendritic cells in lymph nodes of melanoma patients. Cancer Res 2009 1.02
81 Human plasmacytoid dendritic cells phagocytose, process, and present exogenous particulate antigen. J Immunol 2010 1.02
82 A novel (19)F agent for detection and quantification of human dendritic cells using magnetic resonance imaging. Int J Cancer 2010 1.01
83 Human plasmacytoid dendritic cells: from molecules to intercellular communication network. Front Immunol 2013 0.99
84 Analysis of dendritic cell trafficking using EGFP-transgenic mice. Immunol Lett 2003 0.98
85 The tetraspanin CD37 orchestrates the α(4)β(1) integrin-Akt signaling axis and supports long-lived plasma cell survival. Sci Signal 2012 0.97
86 The C-type lectin DC-SIGN internalizes soluble antigens and HIV-1 virions via a clathrin-dependent mechanism. Eur J Immunol 2009 0.96
87 In vivo colocalization of antigen and CpG [corrected] within dendritic cells is associated with the efficacy of cancer immunotherapy. Cancer Res 2008 0.96
88 Dendritic cells: tools and targets for antitumor vaccination. Expert Rev Vaccines 2005 0.96
89 Targeting of 111In-labeled dendritic cell human vaccines improved by reducing number of cells. Clin Cancer Res 2013 0.96
90 Immunogenicity of dendritic cells pulsed with CEA peptide or transfected with CEA mRNA for vaccination of colorectal cancer patients. Anticancer Res 2010 0.96
91 Harnessing human plasmacytoid dendritic cells as professional APCs. Cancer Immunol Immunother 2012 0.94
92 DEC-205 mediates antigen uptake and presentation by both resting and activated human plasmacytoid dendritic cells. Eur J Immunol 2011 0.94
93 The influence of PEG chain length and targeting moiety on antibody-mediated delivery of nanoparticle vaccines to human dendritic cells. Biomaterials 2011 0.94
94 Cancer-germline gene expression in pediatric solid tumors using quantitative real-time PCR. Int J Cancer 2007 0.93
95 Dendritic cell-based nanovaccines for cancer immunotherapy. Curr Opin Immunol 2013 0.93
96 Monocyte cell surface glycosaminoglycans positively modulate IL-4-induced differentiation toward dendritic cells. J Immunol 2008 0.93
97 The stem cell markers Oct4A, Nanog and c-Myc are expressed in ascites cells and tumor tissue of ovarian cancer patients. Cell Oncol (Dordr) 2013 0.92
98 The nature of activatory and tolerogenic dendritic cell-derived signal II. Front Immunol 2013 0.91
99 Multimodal imaging of nanovaccine carriers targeted to human dendritic cells. Mol Pharm 2011 0.91
100 Levels of complexity in pathogen recognition by C-type lectins. Curr Opin Immunol 2005 0.91
101 Relevance of DC-SIGN in DC-induced T cell proliferation. J Leukoc Biol 2006 0.91
102 Targeting nanoparticles to dendritic cells for immunotherapy. Methods Enzymol 2012 0.91
103 Prophylactic vaccines mimic synthetic CpG oligonucleotides in their ability to modulate immune responses. Mol Immunol 2011 0.91
104 Naturally circulating dendritic cells to vaccinate cancer patients. Oncoimmunology 2013 0.91
105 The role of tetraspanins in the pathogenesis of infectious diseases. Microbes Infect 2009 0.90
106 Polyinosinic polycytidylic acid prevents efficient antigen expression after mRNA electroporation of clinical grade dendritic cells. Cancer Immunol Immunother 2008 0.90
107 Mesenchymal stem cells respond to TNF but do not produce TNF. J Leukoc Biol 2009 0.90
108 Probing cellular heterogeneity in cytokine-secreting immune cells using droplet-based microfluidics. Lab Chip 2013 0.90
109 Phenotypical and functional characterization of clinical-grade dendritic cells. Methods Mol Med 2005 0.89
110 Dominant processes during human dendritic cell maturation revealed by integration of proteome and transcriptome at the pathway level. J Proteome Res 2010 0.89
111 ALCAM/CD166 adhesive function is regulated by the tetraspanin CD9. Cell Mol Life Sci 2012 0.89
112 Unraveling the human dendritic cell phagosome proteome by organellar enrichment ranking. J Proteomics 2011 0.88
113 Human and murine model cell lines for dendritic cell biology evaluated. Immunol Lett 2008 0.88
114 Enhancement of G-CSF-induced stem cell mobilization by antibodies against the beta 2 integrins LFA-1 and Mac-1. Blood 2002 0.88
115 Dynamic coupling of ALCAM to the actin cortex strengthens cell adhesion to CD6. J Cell Sci 2014 0.87
116 Targeted delivery of a sialic acid-blocking glycomimetic to cancer cells inhibits metastatic spread. ACS Nano 2015 0.87
117 DC-ATLAS: a systems biology resource to dissect receptor specific signal transduction in dendritic cells. Immunome Res 2010 0.87
118 Infection of dendritic cells with herpes simplex virus type 1 induces rapid degradation of CYTIP, thereby modulating adhesion and migration. Blood 2011 0.87
119 Distinct kinetic and mechanical properties govern ALCAM-mediated interactions as shown by single-molecule force spectroscopy. J Cell Sci 2007 0.87
120 Geometry sensing by dendritic cells dictates spatial organization and PGE(2)-induced dissolution of podosomes. Cell Mol Life Sci 2011 0.87
121 Eradicating cancer cells: struggle with a chameleon. Oncotarget 2011 0.86
122 Vaccine-specific local T cell reactivity in immunotherapy-associated vitiligo in melanoma patients. Cancer Immunol Immunother 2008 0.86
123 In vivo targeting of DC-SIGN-positive antigen-presenting cells in a nonhuman primate model. J Immunother 2007 0.86
124 Novel monoclonal antibodies detect elevated levels of the chemokine CCL18/DC-CK1 in serum and body fluids in pathological conditions. J Leukoc Biol 2005 0.86
125 Dynamic re-organization of individual adhesion nanoclusters in living cells by ligand-patterned surfaces. Small 2009 0.85
126 TLR4-mediated podosome loss discriminates gram-negative from gram-positive bacteria in their capacity to induce dendritic cell migration and maturation. J Immunol 2009 0.85
127 Antigen localization controls T cell-mediated tumor immunity. J Immunol 2011 0.85
128 Comparison of antibodies and carbohydrates to target vaccines to human dendritic cells via DC-SIGN. Biomaterials 2012 0.85
129 The neck region of the C-type lectin DC-SIGN regulates its surface spatiotemporal organization and virus-binding capacity on antigen-presenting cells. J Biol Chem 2012 0.85
130 Engineering monocyte-derived dendritic cells to secrete interferon-α enhances their ability to promote adaptive and innate anti-tumor immune effector functions. Cancer Immunol Immunother 2015 0.85
131 "Sweet talk": closing in on C type lectin signaling. Immunity 2005 0.84
132 Syntenin-1 and ezrin proteins link activated leukocyte cell adhesion molecule to the actin cytoskeleton. J Biol Chem 2014 0.83
133 Interaction of acute lymphopblastic leukemia cells with C-type lectins DC-SIGN and L-SIGN. Exp Hematol 2008 0.83
134 Cytoskeletal restraints regulate homotypic ALCAM-mediated adhesion through PKCalpha independently of Rho-like GTPases. J Cell Sci 2004 0.83
135 No advantage of cell-penetrating peptides over receptor-specific antibodies in targeting antigen to human dendritic cells for cross-presentation. J Immunol 2008 0.83
136 The lymphoid chemokine CCL21 triggers LFA-1 adhesive properties on human dendritic cells. Immunol Cell Biol 2010 0.83
137 In vivo recruitment of hematopoietic cells using stromal cell-derived factor 1 alpha-loaded heparinized three-dimensional collagen scaffolds. Tissue Eng Part A 2009 0.83
138 Cell tracking using multimodal imaging. Contrast Media Mol Imaging 2013 0.83
139 Hematopoietic stem cells are coordinated by the molecular cues of the endosteal niche. Stem Cells Dev 2010 0.82
140 Cord blood mesenchymal stem cells suppress DC-T Cell proliferation via prostaglandin B2. Stem Cells Dev 2014 0.82
141 Automated podosome identification and characterization in fluorescence microscopy images. Microsc Microanal 2013 0.82
142 The modular nature of dendritic cell responses to commensal and pathogenic fungi. PLoS One 2012 0.82
143 Tetraspanin CD37 protects against the development of B cell lymphoma. J Clin Invest 2016 0.81
144 C-type lectins on dendritic cells and their interaction with pathogen-derived and endogenous glycoconjugates. Curr Protein Pept Sci 2006 0.81
145 The tetraspanin CD37 protects against glomerular IgA deposition and renal pathology. Am J Pathol 2010 0.81
146 Presence and localization of T-cell subsets in relation to melanocyte differentiation antigen expression and tumour regression as assessed by immunohistochemistry and molecular analysis of microdissected T cells. J Pathol 2004 0.81
147 Mesenchymal stromal cells: tissue engineers and immune response modulators. Arch Immunol Ther Exp (Warsz) 2008 0.81
148 Activation of human plasmacytoid dendritic cells by TLR9 impairs Fc gammaRII-mediated uptake of immune complexes and presentation by MHC class II. J Immunol 2008 0.80
149 An automated multi well cell track system to study leukocyte migration. J Immunol Methods 2003 0.80
150 Immune-related Adverse Events of Dendritic Cell Vaccination Correlate With Immunologic and Clinical Outcome in Stage III and IV Melanoma Patients. J Immunother 2016 0.79
151 Cord blood mesenchymal stem cells propel human dendritic cells to an intermediate maturation state and boost interleukin-12 production by mature dendritic cells. Immunology 2009 0.79
152 Functional OCT4-specific CD4(+) and CD8(+) T cells in healthy controls and ovarian cancer patients. Oncoimmunology 2013 0.79
153 Cytokine profiles in cyst fluids from ovarian tumors reflect immunosuppressive state of the tumor. Int J Gynecol Cancer 2011 0.79
154 IL-4 and IL-13 alter plasmacytoid dendritic cell responsiveness to CpG DNA and herpes simplex virus-1. J Invest Dermatol 2010 0.79
155 The chemotherapeutic drug oxaliplatin differentially affects blood DC function dependent on environmental cues. Cancer Immunol Immunother 2011 0.79
156 Antibodies and carbohydrate ligands binding to DC-SIGN differentially modulate receptor trafficking. Eur J Immunol 2012 0.79
157 Phenotypic and functional characterization of mature dendritic cells from pediatric cancer patients. Pediatr Blood Cancer 2007 0.79
158 In vivo 19F MRI for cell tracking. J Vis Exp 2013 0.78
159 Selective cancer-germline gene expression in pediatric brain tumors. J Neurooncol 2008 0.78
160 Dendritic cell subsets digested: RNA sensing makes the difference! Immunity 2010 0.78
161 Tracking targeted bimodal nanovaccines: immune responses and routing in cells, tissue, and whole organism. Mol Pharm 2014 0.78
162 Reducing cell number improves the homing of dendritic cells to lymph nodes upon intradermal vaccination. Oncoimmunology 2013 0.78
163 Enhancing immunogenicity and cross-reactivity of HIV-1 antigens by in vivo targeting to dendritic cells. Nanomedicine (Lond) 2012 0.77
164 Polymer-based synthetic dendritic cells for tailoring robust and multifunctional T cell responses. ACS Chem Biol 2014 0.77
165 In vivo tracking techniques for cellular regeneration, replacement, and redirection. J Nucl Med 2012 0.77
166 Development of 111In-labeled tumor-associated antigen peptides for monitoring dendritic-cell-based vaccination. Nucl Med Biol 2006 0.77
167 Renal cell carcinoma-associated antigen G250 encodes a naturally processed epitope presented by human leukocyte antigen-DR molecules to CD4(+) T lymphocytes. Int J Cancer 2002 0.76
168 Importance of helper T-cell activation in dendritic cell-based anticancer immunotherapy. Oncoimmunology 2013 0.76
169 In vivo imaging of therapy-induced anti-cancer immune responses in humans. Cell Mol Life Sci 2012 0.76
170 Insight into the dynamics, localization and magnitude of antigen-specific immune responses by [(18)F]FLT PET imaging. Oncoimmunology 2012 0.75
171 Aiming to immune elimination of ovarian cancer stem cells. World J Stem Cells 2013 0.75
172 Multispectral imaging reveals the tissue distribution of tetraspanins in human lymphoid organs. Histochem Cell Biol 2015 0.75
173 Ceramic hydroxyapatite coating on titanium implants drives selective bone marrow stromal cell adhesion. Clin Oral Implants Res 2003 0.75
174 Molecular friction as a tool to identify functionalized alkanethiols. Langmuir 2010 0.75
175 Differentiating stem cells mask their origins. Stem Cells 2004 0.75
176 Binding of the adhesion and pathogen receptor DC-SIGN by monocytes is regulated by the density of Lewis X molecules. Mol Immunol 2006 0.75