Published in J Immunol on May 15, 2005
Resolution of a chronic viral infection after interleukin-10 receptor blockade. J Exp Med (2006) 4.97
Lymphoid tissue inducer-like cells are an innate source of IL-17 and IL-22. J Exp Med (2008) 4.95
Effector T cells control lung inflammation during acute influenza virus infection by producing IL-10. Nat Med (2009) 4.22
Detrimental contribution of the Toll-like receptor (TLR)3 to influenza A virus-induced acute pneumonia. PLoS Pathog (2006) 3.04
Microbiota restricts trafficking of bacteria to mesenteric lymph nodes by CX(3)CR1(hi) cells. Nature (2013) 2.95
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Heterologous immunity between viruses. Immunol Rev (2010) 2.20
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Memory phenotype CD8+ T cells with innate function selectively develop in the absence of active Itk. Eur J Immunol (2007) 1.46
IFN-γ- and IL-10-expressing virus epitope-specific Foxp3(+) T reg cells in the central nervous system during encephalomyelitis. J Exp Med (2011) 1.45
Mice completely lacking immunoproteasomes show major changes in antigen presentation. Nat Immunol (2011) 1.45
Suboptimal activation of antigen-specific CD4+ effector cells enables persistence of M. tuberculosis in vivo. PLoS Pathog (2011) 1.40
Inhibition of protein trafficking by coxsackievirus b3: multiple viral proteins target a single organelle. J Virol (2006) 1.34
Perforin is a critical physiologic regulator of T-cell activation. Blood (2011) 1.32
An extremely diverse CD4 response to vaccinia virus in humans is revealed by proteome-wide T-cell profiling. J Virol (2008) 1.27
Tentative T cells: memory cells are quick to respond, but slow to divide. PLoS Pathog (2008) 1.25
Langerin(neg) conventional dendritic cells produce IL-23 to drive psoriatic plaque formation in mice. Proc Natl Acad Sci U S A (2013) 1.24
Induction and function of virus-specific CD4+ T cell responses. Virology (2011) 1.18
IFN-alpha beta and self-MHC divert CD8 T cells into a distinct differentiation pathway characterized by rapid acquisition of effector functions. J Immunol (2010) 1.14
Critical role of the interleukin-17/interleukin-17 receptor axis in regulating host susceptibility to respiratory infection with Chlamydia species. Infect Immun (2009) 1.13
Autocrine regulation of pulmonary inflammation by effector T-cell derived IL-10 during infection with respiratory syncytial virus. PLoS Pathog (2011) 1.12
B-cell fate decisions following influenza virus infection. Eur J Immunol (2010) 1.12
Maturation-dependent licensing of naive T cells for rapid TNF production. PLoS One (2010) 1.09
Protecting and rescuing the effectors: roles of differentiation and survival in the control of memory T cell development. Front Immunol (2013) 1.08
CD4+ T cell-dependent IFN-γ production by CD8+ effector T cells in Mycobacterium tuberculosis infection. J Immunol (2012) 1.03
Host innate recognition of an intestinal bacterial pathogen induces TRIF-dependent protective immunity. J Exp Med (2011) 1.02
Influenza-infected neutrophils within the infected lungs act as antigen presenting cells for anti-viral CD8(+) T cells. PLoS One (2012) 1.01
CD4 T-cell-mediated heterologous immunity between mycobacteria and poxviruses. J Virol (2009) 1.00
Modulation of the Bcl-2 family blocks sepsis-induced depletion of dendritic cells and macrophages. Shock (2009) 1.00
Heterologous immunity: immunopathology, autoimmunity and protection during viral infections. Autoimmunity (2011) 0.98
Infiltrating macrophages are key to the development of seizures following virus infection. J Virol (2012) 0.98
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Gammaherpesvirus latency accentuates EAE pathogenesis: relevance to Epstein-Barr virus and multiple sclerosis. PLoS Pathog (2012) 0.96
Radioiodinated DPA-713 imaging correlates with bactericidal activity of tuberculosis treatments in mice. Antimicrob Agents Chemother (2014) 0.96
Microbial amyloids induce interleukin 17A (IL-17A) and IL-22 responses via Toll-like receptor 2 activation in the intestinal mucosa. Infect Immun (2012) 0.95
Interleukin (IL)-21-independent pathogen-specific CD8+ T-cell expansion, and IL-21-dependent suppression of CD4+ T-cell IL-17 production. Immunology (2010) 0.90
Myelin oligodendrocyte glycoprotein peptide-induced experimental allergic encephalomyelitis and T cell responses are unaffected by immunoproteasome deficiency. J Neuroimmunol (2007) 0.87
Thymomegaly, microsplenia, and defective homeostatic proliferation of peripheral lymphocytes in p51-Ets1 isoform-specific null mice. Mol Cell Biol (2007) 0.85
Distinct APC subtypes drive spatially segregated CD4+ and CD8+ T-cell effector activity during skin infection with HSV-1. PLoS Pathog (2014) 0.84
Interferon-γ-producing immature myeloid cells confer protection against severe invasive group A Streptococcus infections. Nat Commun (2012) 0.84
Innate IFN-γ-producing cells in the spleen of mice early after Listeria monocytogenes infection: importance of microenvironment of the cells involved in the production of innate IFN-γ. Front Immunol (2011) 0.83
Therapeutic regulatory T cells subvert effector T cell function in inflamed islets to halt autoimmune diabetes. J Immunol (2015) 0.82
Immune requirements of post-exposure immunization with modified vaccinia Ankara of lethally infected mice. PLoS One (2010) 0.82
CD4+ T cells are trigger and target of the glucocorticoid response that prevents lethal immunopathology in toxoplasma infection. J Exp Med (2013) 0.82
Age-Associated Resident Memory CD8 T Cells in the Central Nervous System Are Primed To Potentiate Inflammation after Ischemic Brain Injury. J Immunol (2016) 0.82
CD8 T cells in innate immune responses: using STAT4-dependent but antigen-independent pathways to gamma interferon during viral infection. MBio (2014) 0.81
Type I interferons promote severe disease in a mouse model of lethal ehrlichiosis. Infect Immun (2014) 0.81
CD8+ memory T cells appear exhausted within hours of acute virus infection. J Immunol (2013) 0.81
Neural innervation stimulates splenic TFF2 to arrest myeloid cell expansion and cancer. Nat Commun (2016) 0.80
Chronic ethanol exposure selectively inhibits the influenza-specific CD8 T cell response during influenza a virus infection. Alcohol Clin Exp Res (2014) 0.80
Antigen-specific naive CD8+ T cells produce a single pulse of IFN-γ in vivo within hours of infection, but without antiviral effect. J Immunol (2014) 0.79
An MHC class Ib-restricted CD8+ T cell response to lymphocytic choriomeningitis virus. J Immunol (2011) 0.78
The nature of innate and adaptive interleukin-17A responses in sham or bacterial inoculation. Immunology (2012) 0.78
S. mansoni bolsters anti-viral immunity in the murine respiratory tract. PLoS One (2014) 0.77
Cognate antigen stimulation generates potent CD8(+) inflammatory effector T cells. Front Immunol (2013) 0.77
A novel human-derived antibody against NY-ESO-1 improves the efficacy of chemotherapy. Cancer Immun (2013) 0.76
Immunotherapy Expands and Maintains the Function of High-Affinity Tumor-Infiltrating CD8 T Cells In Situ. J Immunol (2016) 0.75
Type I IFN Signaling Is Dispensable during Secondary Viral Infection. PLoS Pathog (2016) 0.75
PDGF-BB Promotes Type I IFN-Dependent Vascular Alterations and Monocyte Recruitment in a Model of Dermal Fibrosis. PLoS One (2016) 0.75
TCR independent suppression of CD8(+) T cell cytokine production mediated by IFNγ in vivo. Virology (2016) 0.75
Host-Derived CD70 Suppresses Murine Graft-versus-Host Disease by Limiting Donor T Cell Expansion and Effector Function. J Immunol (2017) 0.75
Successful Treatment of T Cell-Mediated Acute Rejection with Delayed CTLA4-Ig in Mice. Front Immunol (2017) 0.75
Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy (2012) 20.08
Recombinant vaccinia virus-induced T-cell immunity: quantitation of the response to the virus vector and the foreign epitope. J Virol (2002) 2.64
Interferon-gamma acts directly on CD8+ T cells to increase their abundance during virus infection. J Exp Med (2005) 2.13
Cell cycle status affects coxsackievirus replication, persistence, and reactivation in vitro. J Virol (2002) 1.92
Molecular mimicry, bystander activation, or viral persistence: infections and autoimmune disease. Clin Microbiol Rev (2006) 1.81
Precursor frequency, nonlinear proliferation, and functional maturation of virus-specific CD4+ T cells. J Immunol (2006) 1.76
Microorganisms and autoimmunity: making the barren field fertile? Nat Rev Microbiol (2003) 1.76
Coxsackievirus B3 and the neonatal CNS: the roles of stem cells, developing neurons, and apoptosis in infection, viral dissemination, and disease. Am J Pathol (2003) 1.48
Immunodominance in virus-induced CD8(+) T-cell responses is dramatically modified by DNA immunization and is regulated by gamma interferon. J Virol (2002) 1.42
Coxsackievirus infection induces autophagy-like vesicles and megaphagosomes in pancreatic acinar cells in vivo. J Virol (2010) 1.38
Inhibition of protein trafficking by coxsackievirus b3: multiple viral proteins target a single organelle. J Virol (2006) 1.34
Detection of intracellular cytokines by flow cytometry. Curr Protoc Immunol (2007) 1.32
Short-term fasting induces profound neuronal autophagy. Autophagy (2010) 1.28
Cutting edge: early IFN-gamma signaling directly enhances primary antiviral CD4+ T cell responses. J Immunol (2005) 1.27
Direct interferon-gamma signaling dramatically enhances CD4+ and CD8+ T cell memory. J Immunol (2007) 1.27
Tentative T cells: memory cells are quick to respond, but slow to divide. PLoS Pathog (2008) 1.25
Immunoproteasome-deficient mice mount largely normal CD8+ T cell responses to lymphocytic choriomeningitis virus infection and DNA vaccination. J Immunol (2005) 1.23
Persistent macrophage/microglial activation and myelin disruption after experimental autoimmune encephalomyelitis in tissue inhibitor of metalloproteinase-1-deficient mice. Am J Pathol (2006) 1.14
The rapidity with which virus-specific CD8+ T cells initiate IFN-gamma synthesis increases markedly over the course of infection and correlates with immunodominance. J Immunol (2004) 1.12
Astrocytic tissue inhibitor of metalloproteinase-1 (TIMP-1) promotes oligodendrocyte differentiation and enhances CNS myelination. J Neurosci (2011) 1.11
Viral persistence and chronic immunopathology in the adult central nervous system following Coxsackievirus infection during the neonatal period. J Virol (2009) 1.10
Autophagy, inflammation and neurodegenerative disease. Eur J Neurosci (2010) 1.08
Elevated ATG5 expression in autoimmune demyelination and multiple sclerosis. Autophagy (2009) 1.08
Identification of protective Lassa virus epitopes that are restricted by HLA-A2. J Virol (2006) 1.07
Coxsackievirus targets proliferating neuronal progenitor cells in the neonatal CNS. J Neurosci (2005) 1.06
Pancreatic acinar cell-specific autophagy disruption reduces coxsackievirus replication and pathogenesis in vivo. Cell Host Microbe (2012) 1.05
A novel population of myeloid cells responding to coxsackievirus infection assists in the dissemination of virus within the neonatal CNS. J Neurosci (2010) 1.04
Evaluating the immunogenicity and protective efficacy of a DNA vaccine encoding Lassa virus nucleoprotein. Virology (2005) 1.03
Increasing the CD4+ T cell precursor frequency leads to competition for IFN-gamma thereby degrading memory cell quantity and quality. J Immunol (2008) 1.02
HLA-A2-restricted protection against lethal lymphocytic choriomeningitis. J Virol (2006) 0.99
"Translocatory proteins" and "protein transduction domains": a critical analysis of their biological effects and the underlying mechanisms. Mol Ther (2003) 0.98
Coxsackievirus B3 proteins directionally complement each other to downregulate surface major histocompatibility complex class I. J Virol (2007) 0.97
The contraction phase of virus-specific CD8+ T cells is unaffected by a pan-caspase inhibitor. J Immunol (2004) 0.95
Deletions within the 5'UTR of coxsackievirus B3: consequences for virus translation and replication. Virology (2006) 0.94
Coxsackievirus preferentially replicates and induces cytopathic effects in undifferentiated neural progenitor cells. J Virol (2011) 0.93
Coxsackievirus B3 inhibits antigen presentation in vivo, exerting a profound and selective effect on the MHC class I pathway. PLoS Pathog (2009) 0.91
Neonates mount robust and protective adult-like CD8(+)-T-cell responses to DNA vaccines. J Virol (2002) 0.90
Targeting plasmid-encoded proteins to the antigen presentation pathways. Immunol Rev (2004) 0.90
Coxsackievirus replication and the cell cycle: a potential regulatory mechanism for viral persistence/latency. Med Microbiol Immunol (2003) 0.89
Peptide vaccination of mice immune to LCMV or vaccinia virus causes serious CD8 T cell-mediated, TNF-dependent immunopathology. J Clin Invest (2006) 0.89
Analysis of translational initiation in coxsackievirus B3 suggests an alternative explanation for the high frequency of R+4 in the eukaryotic consensus motif. J Virol (2005) 0.89
DNA vaccination can break immunological tolerance to PrP in wild-type mice and attenuates prion disease after intracerebral challenge. J Virol (2006) 0.88
Myelin oligodendrocyte glycoprotein peptide-induced experimental allergic encephalomyelitis and T cell responses are unaffected by immunoproteasome deficiency. J Neuroimmunol (2007) 0.87
Type B coxsackieviruses and their interactions with the innate and adaptive immune systems. Future Microbiol (2010) 0.87
In vivo ablation of type I interferon receptor from cardiomyocytes delays coxsackieviral clearance and accelerates myocardial disease. J Virol (2014) 0.86
Coxsackievirus B3 infects the bone marrow and diminishes the restorative capacity of erythroid and lymphoid progenitors. J Virol (2012) 0.86
Neural stem cell depletion and CNS developmental defects after enteroviral infection. Am J Pathol (2011) 0.86
Amelioration of coxsackievirus B3-mediated myocarditis by inhibition of tissue inhibitors of matrix metalloproteinase-1. Am J Pathol (2007) 0.86
Fatal neonatal myocarditis caused by a recombinant human enterovirus-B variant. Pediatr Infect Dis J (2008) 0.85
Wild-type coxsackievirus infection dramatically alters the abundance, heterogeneity, and immunostimulatory capacity of conventional dendritic cells in vivo. Virology (2012) 0.84
Mice deficient in stem cell antigen-1 (Sca1, Ly-6A/E) develop normal primary and memory CD4+ and CD8+ T-cell responses to virus infection. Eur J Immunol (2009) 0.83
Interactions between enteroviruses and autophagy in vivo. Autophagy (2012) 0.82
Enumeration and functional evaluation of virus-specific CD4+ and CD8+ T cells in lymphoid and peripheral sites of coxsackievirus B3 infection. J Virol (2008) 0.82
A multivalent vaccination strategy for the prevention of Old World arenavirus infection in humans. J Virol (2010) 0.82
Generation and analysis of an RNA vaccine that protects against coxsackievirus B3 challenge. Virology (2004) 0.81
CD8+ memory T cells appear exhausted within hours of acute virus infection. J Immunol (2013) 0.81
Targeting myelin proteolipid protein to the MHC class I pathway by ubiquitination modulates the course of experimental autoimmune encephalomyelitis. J Neuroimmunol (2008) 0.80
Infectious RNA isolated from the spinal cords of mice chronically infected with Theiler's murine encephalomyelitis virus. J Virol (2006) 0.79
Differential T cell responses to residual viral antigen prolong CD4+ T cell contraction following the resolution of infection. J Immunol (2013) 0.79
Coxsackievirus can exploit LC3 in both autophagy-dependent and -independent manners in vivo. Autophagy (2015) 0.77