Ionic immune suppression within the tumour microenvironment limits T cell effector function.

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Published in Nature on September 14, 2016

Authors

Robert Eil1, Suman K Vodnala1, David Clever1, Christopher A Klebanoff1,2, Madhusudhanan Sukumar1, Jenny H Pan1, Douglas C Palmer1, Alena Gros1, Tori N Yamamoto1, Shashank J Patel1, Geoffrey C Guittard1, Zhiya Yu1, Valentina Carbonaro3, Klaus Okkenhaug3, David S Schrump1, W Marston Linehan1, Rahul Roychoudhuri3, Nicholas P Restifo1

Author Affiliations

1: National Cancer Institute, National Institutes of Health (NIH), Bethesda, Maryland 20892, USA.
2: Center for Cell Engineering and Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York 10065, USA.
3: Laboratory of Lymphocyte Signalling and Development, The Babraham Institute, Cambridge CB22 3AT, UK.

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