PubRank

Martin Scheffner

Author PubWeight™ 52.01‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Hakai, a c-Cbl-like protein, ubiquitinates and induces endocytosis of the E-cadherin complex. Nat Cell Biol 2002 5.02
2 The ubiquitin ligase HectH9 regulates transcriptional activation by Myc and is essential for tumor cell proliferation. Cell 2005 2.85
3 HdmX stimulates Hdm2-mediated ubiquitination and degradation of p53. Proc Natl Acad Sci U S A 2003 2.73
4 The chaperone-associated ubiquitin ligase CHIP is able to target p53 for proteasomal degradation. J Biol Chem 2005 2.01
5 A non-proteolytic role for ubiquitin in Tat-mediated transactivation of the HIV-1 promoter. Nat Cell Biol 2003 1.82
6 Tip60 is targeted to proteasome-mediated degradation by Mdm2 and accumulates after UV irradiation. EMBO J 2002 1.81
7 Ubiquitination-dependent cofactor exchange on LIM homeodomain transcription factors. Nature 2002 1.80
8 siRNA targeting of the viral E6 oncogene efficiently kills human papillomavirus-positive cancer cells. Oncogene 2003 1.78
9 Role of the histone acetyl transferase Tip60 in the p53 pathway. J Biol Chem 2004 1.56
10 Involvement of the DNA repair protein hHR23 in p53 degradation. Mol Cell Biol 2003 1.38
11 Regulation of p27 degradation and S-phase progression by Ro52 RING finger protein. Mol Cell Biol 2006 1.31
12 UBE1L2, a novel E1 enzyme specific for ubiquitin. J Biol Chem 2007 1.25
13 The role of the ubiquitin ligase E6-AP in human papillomavirus E6-mediated degradation of PDZ domain-containing proteins. J Biol Chem 2006 1.23
14 Regulation of estrogen-dependent transcription by the LIM cofactors CLIM and RLIM in breast cancer. Cancer Res 2009 1.12
15 Hetero-oligomerization with MdmX rescues the ubiquitin/Nedd8 ligase activity of RING finger mutants of Mdm2. J Biol Chem 2007 1.08
16 Regulation of the polycomb protein Ring1B by self-ubiquitination or by E6-AP may have implications to the pathogenesis of Angelman syndrome. Proc Natl Acad Sci U S A 2010 1.07
17 Synthesis of defined ubiquitin dimers. J Am Chem Soc 2010 1.01
18 Role of the ubiquitin ligase E6AP/UBE3A in controlling levels of the synaptic protein Arc. Proc Natl Acad Sci U S A 2013 0.99
19 Physical and functional interaction of the HECT ubiquitin-protein ligases E6AP and HERC2. J Biol Chem 2011 0.98
20 Mutation of HERC2 causes developmental delay with Angelman-like features. J Med Genet 2012 0.98
21 Recognition and cleavage of related to ubiquitin 1 (Rub1) and Rub1-ubiquitin chains by components of the ubiquitin-proteasome system. Mol Cell Proteomics 2012 0.93
22 Growth suppression induced by downregulation of E6-AP expression in human papillomavirus-positive cancer cell lines depends on p53. J Virol 2005 0.91
23 Ubiquitin ligase E6-AP and its role in human disease. Biochem Soc Trans 2008 0.90
24 Ubiquitin binding by a CUE domain regulates ubiquitin chain formation by ERAD E3 ligases. Mol Cell 2013 0.88
25 Generation of a mono-ubiquitinated PCNA mimic by click chemistry. Chembiochem 2011 0.88
26 The ubiquitin-protein ligase activity of Hdm2 is inhibited by nucleic acids. FEBS Lett 2003 0.88
27 Protein tyrosine phosphatase H1 is a target of the E6 oncoprotein of high-risk genital human papillomaviruses. J Gen Virol 2007 0.87
28 Turning the RING domain protein MdmX into an active ubiquitin-protein ligase. J Biol Chem 2010 0.86
29 Functional ubiquitin conjugates with lysine-epsilon-amino-specific linkage by thioether ligation of cysteinyl-ubiquitin peptide building blocks. Bioconjug Chem 2009 0.85
30 Poly(ADP-ribose)-mediated interplay of XPA and PARP1 leads to reciprocal regulation of protein function. FEBS J 2014 0.84
31 Dissecting ubiquitin signaling with linkage-defined and protease resistant ubiquitin chains. Angew Chem Int Ed Engl 2014 0.83
32 A novel peptide motif binding to and blocking the intracellular activity of the human papillomavirus E6 oncoprotein. J Mol Med (Berl) 2008 0.83
33 Roles of larval sea urchin spicule SM50 domains in organic matrix self-assembly and calcium carbonate mineralization. J Struct Biol 2013 0.83
34 Oncolytic adenovirus expressing a p53 variant resistant to degradation by HPV E6 protein exhibits potent and selective replication in cervical cancer. Mol Ther 2005 0.82
35 Ubiquitin-fusion protein system: a powerful tool for ectopic protein expression in mammalian cells. Biotechniques 2009 0.81
36 Differentiation of compact and extended conformations of di-ubiquitin conjugates with lysine-specific isopeptide linkages by ion mobility-mass spectrometry. J Am Soc Mass Spectrom 2011 0.81
37 c-Abl phosphorylates E6AP and regulates its E3 ubiquitin ligase activity. Biochemistry 2013 0.80
38 Oncogenic human papillomaviruses block expression of the B-cell translocation gene-2 tumor suppressor gene. Int J Cancer 2009 0.79
39 Formation of ubiquitin dimers via azide-alkyne click reaction. Methods Mol Biol 2012 0.78
40 Ubiquitin Family Members in the Regulation of the Tumor Suppressor p53. Subcell Biochem 2010 0.77
41 Improving bioorthogonal protein ubiquitylation by click reaction. Bioorg Med Chem 2013 0.76
42 Fluorogenic ATP analogues for online monitoring of ATP consumption: observing ubiquitin activation in real time. Angew Chem Int Ed Engl 2013 0.75
43 Varshavsky's contributions. Science 2004 0.75
44 Selective monitoring of the enzymatic activity of the tumor suppressor Fhit. Angew Chem Int Ed Engl 2014 0.75