Published in Mol Cell on May 27, 2005
Regulating the p53 pathway: in vitro hypotheses, in vivo veritas. Nat Rev Cancer (2006) 8.83
p53 ubiquitination: Mdm2 and beyond. Mol Cell (2006) 5.57
Tumour suppression by p53: a role for the DNA damage response? Nat Rev Cancer (2009) 4.06
USP10 regulates p53 localization and stability by deubiquitinating p53. Cell (2010) 3.17
The p53 orchestra: Mdm2 and Mdmx set the tone. Trends Cell Biol (2010) 3.08
Monoubiquitylation promotes mitochondrial p53 translocation. EMBO J (2007) 2.62
p53 post-translational modification: deregulated in tumorigenesis. Trends Mol Med (2010) 2.54
A stapled p53 helix overcomes HDMX-mediated suppression of p53. Cancer Cell (2010) 2.47
Structural basis of competitive recognition of p53 and MDM2 by HAUSP/USP7: implications for the regulation of the p53-MDM2 pathway. PLoS Biol (2006) 2.35
Increased radioresistance and accelerated B cell lymphomas in mice with Mdmx mutations that prevent modifications by DNA-damage-activated kinases. Cancer Cell (2009) 2.28
Protein partners of deubiquitinating enzymes. Biochem J (2008) 2.15
An essential function of the extreme C-terminus of MDM2 can be provided by MDMX. EMBO J (2006) 2.11
The deubiquitinating enzyme USP2a regulates the p53 pathway by targeting Mdm2. EMBO J (2007) 2.07
Stabilization of the transcription factor Foxp3 by the deubiquitinase USP7 increases Treg-cell-suppressive capacity. Immunity (2013) 2.05
The multiple levels of regulation by p53 ubiquitination. Cell Death Differ (2010) 1.87
Targeting Mdm2 and Mdmx in cancer therapy: better living through medicinal chemistry? Mol Cancer Res (2009) 1.87
A small molecule inhibitor of ubiquitin-specific protease-7 induces apoptosis in multiple myeloma cells and overcomes bortezomib resistance. Cancer Cell (2012) 1.79
The predator becomes the prey: regulating the ubiquitin system by ubiquitylation and degradation. Nat Rev Mol Cell Biol (2011) 1.73
Suppression of cancer cell growth by promoting cyclin D1 degradation. Mol Cell (2009) 1.72
Regulation of MDMX nuclear import and degradation by Chk2 and 14-3-3. EMBO J (2006) 1.67
UV-sensitive syndrome protein UVSSA recruits USP7 to regulate transcription-coupled repair. Nat Genet (2012) 1.63
Quantitative analyses reveal the importance of regulated Hdmx degradation for p53 activation. Proc Natl Acad Sci U S A (2007) 1.56
The p53--Mdm2--HAUSP complex is involved in p53 stabilization by HAUSP. Oncogene (2007) 1.54
p53 regulation by ubiquitin. FEBS Lett (2011) 1.51
Inactivation of HAUSP in vivo modulates p53 function. Oncogene (2009) 1.48
Suppression of the deubiquitinating enzyme USP5 causes the accumulation of unanchored polyubiquitin and the activation of p53. J Biol Chem (2008) 1.43
Regulation of proteolysis by human deubiquitinating enzymes. Biochim Biophys Acta (2013) 1.42
14-3-3gamma binds to MDMX that is phosphorylated by UV-activated Chk1, resulting in p53 activation. EMBO J (2006) 1.40
ATM-dependent downregulation of USP7/HAUSP by PPM1G activates p53 response to DNA damage. Mol Cell (2012) 1.40
Positive regulation of p53 stability and activity by the deubiquitinating enzyme Otubain 1. EMBO J (2011) 1.38
The tumour suppressor RASSF1A promotes MDM2 self-ubiquitination by disrupting the MDM2-DAXX-HAUSP complex. EMBO J (2008) 1.37
Balance of Yin and Yang: ubiquitylation-mediated regulation of p53 and c-Myc. Neoplasia (2006) 1.34
The USP7/Dnmt1 complex stimulates the DNA methylation activity of Dnmt1 and regulates the stability of UHRF1. Nucleic Acids Res (2011) 1.32
M phase phosphorylation of the epigenetic regulator UHRF1 regulates its physical association with the deubiquitylase USP7 and stability. Proc Natl Acad Sci U S A (2012) 1.32
Reverse the curse--the role of deubiquitination in cell cycle control. Curr Opin Cell Biol (2008) 1.31
Deubiquitinases as a signaling target of oxidative stress. Cell Rep (2012) 1.25
Regulation of p53 stability and function by the deubiquitinating enzyme USP42. EMBO J (2011) 1.24
The regulation of the p53-mediated stress response by MDM2 and MDM4. Cold Spring Harb Perspect Biol (2010) 1.23
MDM4 (MDMX) localizes at the mitochondria and facilitates the p53-mediated intrinsic-apoptotic pathway. EMBO J (2009) 1.23
Differential roles of ATM- and Chk2-mediated phosphorylations of Hdmx in response to DNA damage. Mol Cell Biol (2006) 1.22
Emerging role of Lys-63 ubiquitination in protein kinase and phosphatase activation and cancer development. Oncogene (2010) 1.21
Suppression of hypoxia-inducible factor 2alpha restores p53 activity via Hdm2 and reverses chemoresistance of renal carcinoma cells. Cancer Res (2009) 1.18
Epstein-Barr virus nuclear antigen 3C augments Mdm2-mediated p53 ubiquitination and degradation by deubiquitinating Mdm2. J Virol (2009) 1.18
Functions of MDMX in the modulation of the p53-response. J Biomed Biotechnol (2011) 1.12
Pharmacological targets in the ubiquitin system offer new ways of treating cancer, neurodegenerative disorders and infectious diseases. Expert Rev Mol Med (2011) 1.12
Limiting the power of p53 through the ubiquitin proteasome pathway. Genes Dev (2014) 1.10
Mechanism of p53 stabilization by ATM after DNA damage. Cell Cycle (2010) 1.09
Updates on p53: modulation of p53 degradation as a therapeutic approach. Br J Cancer (2008) 1.07
Phosphorylation and degradation of MdmX is inhibited by Wip1 phosphatase in the DNA damage response. Cancer Res (2009) 1.07
MYC is activated by USP2a-mediated modulation of microRNAs in prostate cancer. Cancer Discov (2012) 1.07
Phosphorylation of MDMX mediated by Akt leads to stabilization and induces 14-3-3 binding. J Biol Chem (2008) 1.06
USP7/HAUSP stimulates repair of oxidative DNA lesions. Nucleic Acids Res (2010) 1.06
The Regulation of Multiple p53 Stress Responses is Mediated through MDM2. Genes Cancer (2012) 1.06
Kaposi's sarcoma-associated herpesvirus viral interferon regulatory factor 4 targets MDM2 to deregulate the p53 tumor suppressor pathway. J Virol (2009) 1.03
Deubiquitylating enzymes and DNA damage response pathways. Cell Biochem Biophys (2013) 1.03
Deubiquitinases and the new therapeutic opportunities offered to cancer. Endocr Relat Cancer (2015) 1.02
The herpesvirus associated ubiquitin specific protease, USP7, is a negative regulator of PML proteins and PML nuclear bodies. PLoS One (2011) 1.00
MDM2 and MDMX: Alone and together in regulation of p53. Transl Cancer Res (2012) 1.00
PTMs in conversation: activity and function of deubiquitinating enzymes regulated via post-translational modifications. Cell Biochem Biophys (2011) 1.00
HDMX-L is expressed from a functional p53-responsive promoter in the first intron of the HDMX gene and participates in an autoregulatory feedback loop to control p53 activity. J Biol Chem (2010) 1.00
A role of HAUSP in tumor suppression in a human colon carcinoma xenograft model. Cell Cycle (2008) 0.97
The Mdm network and its regulation of p53 activities: a rheostat of cancer risk. Hum Mutat (2014) 0.97
Ubiquitin-specific protease 7 regulates nucleotide excision repair through deubiquitinating XPC protein and preventing XPC protein from undergoing ultraviolet light-induced and VCP/p97 protein-regulated proteolysis. J Biol Chem (2014) 0.96
Bilateral inhibition of HAUSP deubiquitinase by a viral interferon regulatory factor protein. Nat Struct Mol Biol (2011) 0.96
MDM4 (MDMX) and its Transcript Variants. Curr Genomics (2009) 0.94
Affinity purification strategy to capture human endogenous proteasome complexes diversity and to identify proteasome-interacting proteins. Mol Cell Proteomics (2009) 0.94
Casein kinase 1α regulates an MDMX intramolecular interaction to stimulate p53 binding. Mol Cell Biol (2012) 0.94
Ubiquitin becomes ubiquitous in cancer: emerging roles of ubiquitin ligases and deubiquitinases in tumorigenesis and as therapeutic targets. Cancer Biol Ther (2010) 0.93
The ubiquitin-specific protease USP7 modulates the replication of Kaposi's sarcoma-associated herpesvirus latent episomal DNA. J Virol (2012) 0.92
USP7 deubiquitinase promotes ubiquitin-dependent DNA damage signaling by stabilizing RNF168. Cell Cycle (2015) 0.92
SRC-3 coactivator regulates cell resistance to cytotoxic stress via TRAF4-mediated p53 destabilization. Genes Dev (2013) 0.92
Deubiquitination of Tip60 by USP7 determines the activity of the p53-dependent apoptotic pathway. Mol Cell Biol (2013) 0.91
Protein degradation and the stress response. Semin Cell Dev Biol (2012) 0.91
Roles of HAUSP-mediated p53 regulation in central nervous system development. Cell Death Differ (2011) 0.90
Monoubiquitination is critical for ovarian tumor domain-containing ubiquitin aldehyde binding protein 1 (Otub1) to suppress UbcH5 enzyme and stabilize p53 protein. J Biol Chem (2014) 0.89
A role for USP7 in DNA replication. Mol Cell Biol (2013) 0.86
USP7 is essential for maintaining Rad18 stability and DNA damage tolerance. Oncogene (2015) 0.86
Stabilization of histone demethylase PHF8 by USP7 promotes breast carcinogenesis. J Clin Invest (2016) 0.86
Regulation of vaccinia virus E3 protein by small ubiquitin-like modifier proteins. J Virol (2011) 0.85
Deubiquitinating enzyme regulation of the p53 pathway: A lesson from Otub1. World J Biol Chem (2014) 0.84
Targeting the ubiquitin-mediated proteasome degradation of p53 for cancer therapy. Curr Pharm Des (2013) 0.84
USP7 overexpression predicts a poor prognosis in lung squamous cell carcinoma and large cell carcinoma. Tumour Biol (2014) 0.83
The human T-cell leukemia virus type 1 oncoprotein tax controls forkhead box O4 activity through degradation by the proteasome. J Virol (2011) 0.83
Protein phosphatase 1 inhibits p53 signaling by dephosphorylating and stabilizing Mdmx. Cell Signal (2012) 0.82
Tumor suppressor protein Pdcd4 interacts with Daxx and modulates the stability of Daxx and the Hipk2-dependent phosphorylation of p53 at serine 46. Oncogenesis (2013) 0.82
The Roles of MDM2 and MDMX Phosphorylation in Stress Signaling to p53. Genes Cancer (2012) 0.81
UVSSA and USP7, a new couple in transcription-coupled DNA repair. Chromosoma (2013) 0.81
Stochastic modeling and simulation of the p53-MDM2/MDMX loop. J Comput Biol (2009) 0.81
Crystal Structure of USP7 Ubiquitin-like Domains with an ICP0 Peptide Reveals a Novel Mechanism Used by Viral and Cellular Proteins to Target USP7. PLoS Pathog (2015) 0.80
OTUD5 regulates p53 stability by deubiquitinating p53. PLoS One (2013) 0.80
The shelterin component TPP1 is a binding partner and substrate for the deubiquitinating enzyme USP7. J Biol Chem (2014) 0.78
The E3 ubiquitin ligase ARIH1 protects against genotoxic stress by initiating a 4EHP-mediated mRNA translation arrest. Mol Cell Biol (2015) 0.78
STIP is a critical nuclear scaffolding protein linking USP7 to p53-Mdm2 pathway regulation. Oncotarget (2015) 0.77
The yin-yang of DNA damage response: roles in tumorigenesis and cellular senescence. Int J Mol Sci (2013) 0.76
Involvement of p63 in the herpes simplex virus-1-induced demise of corneal cells. J Biomed Sci (2010) 0.76
Identification of Kaposi Sarcoma Herpesvirus (KSHV) vIRF1 Protein as a Novel Interaction Partner of Human Deubiquitinase USP7. J Biol Chem (2016) 0.76
Regulation of the Mdm2-p53 signaling axis in the DNA damage response and tumorigenesis. Transl Cancer Res (2016) 0.76
K63-polyubiquitinated HAUSP deubiquitinates HIF-1α and dictates H3K56 acetylation promoting hypoxia-induced tumour progression. Nat Commun (2016) 0.75
Stabilization of Ultraviolet (UV)-stimulated Scaffold Protein A by Interaction with Ubiquitin-specific Peptidase 7 Is Essential for Transcription-coupled Nucleotide Excision Repair. J Biol Chem (2016) 0.75
Inactivation of the p53 pathway in retinoblastoma. Nature (2006) 4.57
Regulation of sexual development of Plasmodium by translational repression. Science (2006) 4.15
FOXO4 transcriptional activity is regulated by monoubiquitination and USP7/HAUSP. Nat Cell Biol (2006) 4.14
The SUMO modification pathway is involved in the BRCA1 response to genotoxic stress. Nature (2009) 3.62
Chemistry-based functional proteomics reveals novel members of the deubiquitinating enzyme family. Chem Biol (2002) 3.43
A novel orally active proteasome inhibitor induces apoptosis in multiple myeloma cells with mechanisms distinct from Bortezomib. Cancer Cell (2005) 3.41
Wnt signaling through inhibition of β-catenin degradation in an intact Axin1 complex. Cell (2012) 3.03
Design and use of conditional MHC class I ligands. Nat Med (2006) 3.01
MDMX: from bench to bedside. J Cell Sci (2007) 2.78
Distinct gene mutation profiles among luminal-type and basal-type breast cancer cell lines. Breast Cancer Res Treat (2009) 2.76
Tumour suppressor RNF43 is a stem-cell E3 ligase that induces endocytosis of Wnt receptors. Nature (2012) 2.76
Structure of the ubiquitin hydrolase UCH-L3 complexed with a suicide substrate. J Biol Chem (2004) 2.75
Mutual dependence of MDM2 and MDMX in their functional inactivation of p53. J Biol Chem (2002) 2.68
Amplification of Mdmx (or Mdm4) directly contributes to tumor formation by inhibiting p53 tumor suppressor activity. Mol Cell Biol (2004) 2.61
Crystal structure of the boronic acid-based proteasome inhibitor bortezomib in complex with the yeast 20S proteasome. Structure (2006) 2.56
Generation of peptide-MHC class I complexes through UV-mediated ligand exchange. Nat Protoc (2006) 2.47
Mst4 and Ezrin induce brush borders downstream of the Lkb1/Strad/Mo25 polarization complex. Dev Cell (2009) 2.40
Wingless secretion requires endosome-to-Golgi retrieval of Wntless/Evi/Sprinter by the retromer complex. Nat Cell Biol (2008) 2.38
Increased radioresistance and accelerated B cell lymphomas in mice with Mdmx mutations that prevent modifications by DNA-damage-activated kinases. Cancer Cell (2009) 2.28
Zinc-finger protein A20, a regulator of inflammation and cell survival, has de-ubiquitinating activity. Biochem J (2004) 2.23
Loss of the tumor suppressor CYLD enhances Wnt/beta-catenin signaling through K63-linked ubiquitination of Dvl. Mol Cell (2010) 2.13
Differential dependence of CD4+CD25+ regulatory and natural killer-like T cells on signals leading to NF-kappaB activation. Proc Natl Acad Sci U S A (2004) 2.09
Stabilization of the transcription factor Foxp3 by the deubiquitinase USP7 increases Treg-cell-suppressive capacity. Immunity (2013) 2.05
OTU deubiquitinases reveal mechanisms of linkage specificity and enable ubiquitin chain restriction analysis. Cell (2013) 2.05
Phenotype of a herpes simplex virus type 1 mutant that fails to express immediate-early regulatory protein ICP0. J Virol (2004) 2.03
Disease-associated prion protein oligomers inhibit the 26S proteasome. Mol Cell (2007) 2.01
Visualizing telomere dynamics in living mammalian cells using PNA probes. EMBO J (2003) 1.99
Phosphorylation of Hdmx mediates its Hdm2- and ATM-dependent degradation in response to DNA damage. Proc Natl Acad Sci U S A (2005) 1.97
Hdmx protein stability is regulated by the ubiquitin ligase activity of Mdm2. J Biol Chem (2003) 1.93
Universal features of post-transcriptional gene regulation are critical for Plasmodium zygote development. PLoS Pathog (2010) 1.90
Specific and covalent targeting of conjugating and deconjugating enzymes of ubiquitin-like proteins. Mol Cell Biol (2004) 1.86
Mdmx as an essential regulator of p53 activity. Biochem Biophys Res Commun (2005) 1.85
Identification and characterization of the first small molecule inhibitor of MDMX. J Biol Chem (2010) 1.85
Chemical synthesis of ubiquitin, ubiquitin-based probes, and diubiquitin. Angew Chem Int Ed Engl (2010) 1.83
Structural basis of substrate discrimination and integrin binding by autotaxin. Nat Struct Mol Biol (2011) 1.81
Boronic acid-based inhibitor of autotaxin reveals rapid turnover of LPA in the circulation. Proc Natl Acad Sci U S A (2010) 1.80
Activity probe for in vivo profiling of the specificity of proteasome inhibitor bortezomib. Nat Methods (2005) 1.78
Conditional MHC class I ligands and peptide exchange technology for the human MHC gene products HLA-A1, -A3, -A11, and -B7. Proc Natl Acad Sci U S A (2008) 1.77
A RING finger ubiquitin ligase is protected from autocatalyzed ubiquitination and degradation by binding to ubiquitin-specific protease USP7. J Biol Chem (2004) 1.76
A viral E3 ligase targets RNF8 and RNF168 to control histone ubiquitination and DNA damage responses. EMBO J (2010) 1.75
Poly(A)+ RNAs roam the cell nucleus and pass through speckle domains in transcriptionally active and inactive cells. J Cell Biol (2004) 1.74
Genetic analysis of BRCA1 ubiquitin ligase activity and its relationship to breast cancer susceptibility. Hum Mol Genet (2006) 1.70
The differential modulation of USP activity by internal regulatory domains, interactors and eight ubiquitin chain types. Chem Biol (2011) 1.58
Mechanism of USP7/HAUSP activation by its C-terminal ubiquitin-like domain and allosteric regulation by GMP-synthetase. Mol Cell (2011) 1.56
DNA damage-induced phosphorylation of MdmX at serine 367 activates p53 by targeting MdmX for Mdm2-dependent degradation. Mol Cell Biol (2005) 1.56
An ankyrin-repeat ubiquitin-binding domain determines TRABID's specificity for atypical ubiquitin chains. Nat Struct Mol Biol (2011) 1.55
CEP-18770: A novel, orally active proteasome inhibitor with a tumor-selective pharmacologic profile competitive with bortezomib. Blood (2007) 1.54
A fluorescent broad-spectrum proteasome inhibitor for labeling proteasomes in vitro and in vivo. Chem Biol (2006) 1.54
Critical role for a central part of Mdm2 in the ubiquitylation of p53. Mol Cell Biol (2003) 1.51
Mdmx and Mdm2: brothers in arms? Cell Cycle (2004) 1.44
The deubiquitinating enzyme UCH-L3 regulates the apical membrane recycling of the epithelial sodium channel. J Biol Chem (2007) 1.43
The intrinsic antiviral defense to incoming HSV-1 genomes includes specific DNA repair proteins and is counteracted by the viral protein ICP0. PLoS Pathog (2011) 1.37
p53: a guide to apoptosis. Curr Cancer Drug Targets (2008) 1.33
On terminal alkynes that can react with active-site cysteine nucleophiles in proteases. J Am Chem Soc (2013) 1.32
Comparison of the biological and biochemical activities of several members of the alphaherpesvirus ICP0 family of proteins. J Virol (2010) 1.32
Drug-induced histone eviction from open chromatin contributes to the chemotherapeutic effects of doxorubicin. Nat Commun (2013) 1.31
SUMO pathway dependent recruitment of cellular repressors to herpes simplex virus type 1 genomes. PLoS Pathog (2011) 1.30
ATM-mediated phosphorylations inhibit Mdmx/Mdm2 stabilization by HAUSP in favor of p53 activation. Cell Cycle (2005) 1.29
Elevated p53 expression is associated with dysregulation of the ubiquitin-proteasome system in dilated cardiomyopathy. Cardiovasc Res (2008) 1.28
Two novel ubiquitin-fold modifier 1 (Ufm1)-specific proteases, UfSP1 and UfSP2. J Biol Chem (2006) 1.26
Interplay between viruses and host sumoylation pathways. Nat Rev Microbiol (2013) 1.26
Comparative selectivity and specificity of the proteasome inhibitors BzLLLCOCHO, PS-341, and MG-132. Cancer Res (2006) 1.25
Recombination-induced tag exchange to track old and new proteins. Proc Natl Acad Sci U S A (2009) 1.23
Differential roles of ATM- and Chk2-mediated phosphorylations of Hdmx in response to DNA damage. Mol Cell Biol (2006) 1.22
Autotaxin and its product lysophosphatidic acid suppress brown adipose differentiation and promote diet-induced obesity in mice. Mol Endocrinol (2012) 1.21
Activity profiling of deubiquitinating enzymes in cervical carcinoma biopsies and cell lines. Mol Carcinog (2006) 1.17
Constitutive lymphocyte transmigration across the basal lamina of high endothelial venules is regulated by the autotaxin/lysophosphatidic acid axis. J Immunol (2013) 1.16
Immunotherapeutic potential for ceramide-based activators of iNKT cells. Trends Pharmacol Sci (2005) 1.16
Ubiquitin-specific protease-like 1 (USPL1) is a SUMO isopeptidase with essential, non-catalytic functions. EMBO Rep (2012) 1.15
In vivo role of lipid adducts on Wingless. J Cell Sci (2008) 1.14
A Genome-wide multidimensional RNAi screen reveals pathways controlling MHC class II antigen presentation. Cell (2011) 1.14
Canonical Wnt signaling negatively modulates regulatory T cell function. Immunity (2013) 1.13
Automated online sequential isotope labeling for protein quantitation applied to proteasome tissue-specific diversity. Mol Cell Proteomics (2008) 1.13
Functions of MDMX in the modulation of the p53-response. J Biomed Biotechnol (2011) 1.12
Chemical evolution of autotaxin inhibitors. Chem Rev (2012) 1.12
A glue for heterochromatin maintenance: stable SUV39H1 binding to heterochromatin is reinforced by the SET domain. J Cell Biol (2005) 1.10
Alternate splicing of the p53 inhibitor HDMX offers a superior prognostic biomarker than p53 mutation in human cancer. Cancer Res (2012) 1.09
c-Abl phosphorylates Hdmx and regulates its interaction with p53. J Biol Chem (2008) 1.09
The various roles of ubiquitin in Wnt pathway regulation. Cell Cycle (2010) 1.08
Messing up disorder: how do missense mutations in the tumor suppressor protein APC lead to cancer? Mol Cancer (2011) 1.08
Wnt/β-catenin signaling requires interaction of the Dishevelled DEP domain and C terminus with a discontinuous motif in Frizzled. Proc Natl Acad Sci U S A (2012) 1.07
Mobile foci of Sp100 do not contain PML: PML bodies are immobile but PML and Sp100 proteins are not. J Struct Biol (2002) 1.07
Small-molecule inhibitors and probes for ubiquitin- and ubiquitin-like-specific proteases. Chembiochem (2005) 1.07
The nuclear lamina promotes telomere aggregation and centromere peripheral localization during senescence of human mesenchymal stem cells. J Cell Sci (2008) 1.06
Viral E3 ubiquitin ligase-mediated degradation of a cellular E3: viral mimicry of a cellular phosphorylation mark targets the RNF8 FHA domain. Mol Cell (2012) 1.06
Class I negative CD8 T cells reveal the confounding role of peptide-transfer onto CD8 T cells stimulated with soluble H2-Kb molecules. Proc Natl Acad Sci U S A (2002) 1.06
MDMX stability is regulated by p53-induced caspase cleavage in NIH3T3 mouse fibroblasts. Oncogene (2002) 1.04
Central chondrosarcoma progression is associated with pRb pathway alterations: CDK4 down-regulation and p16 overexpression inhibit cell growth in vitro. J Cell Mol Med (2008) 1.04
Herpes simplex virus type 1 induces CD83 degradation in mature dendritic cells with immediate-early kinetics via the cellular proteasome. J Virol (2007) 1.03
Nonhydrolyzable ubiquitin-isopeptide isosteres as deubiquitinating enzyme probes. J Am Chem Soc (2010) 1.03
Cytoplasmic tethering is involved in synergistic inhibition of p53 by Mdmx and Mdm2. Cancer Sci (2009) 1.03
Stress-induced responses of human skin fibroblasts in vitro reflect human longevity. Aging Cell (2009) 1.02
Changes in lamina structure are followed by spatial reorganization of heterochromatic regions in caspase-8-activated human mesenchymal stem cells. J Cell Sci (2006) 1.02
Ritonavir induces endoplasmic reticulum stress and sensitizes sarcoma cells toward bortezomib-induced apoptosis. Mol Cancer Ther (2008) 1.01
Profiling proteasome activity in tissue with fluorescent probes. Mol Pharm (2007) 1.01
High-throughput T-cell epitope discovery through MHC peptide exchange. Methods Mol Biol (2009) 1.00