Published in J Immunol on July 01, 2005
Induction of transplantation tolerance to fully mismatched cardiac allografts by T cell mediated delivery of alloantigen. Clin Immunol (2010) 1.42
Immunologic basis of graft rejection and tolerance following transplantation of liver or other solid organs. Gastroenterology (2010) 1.39
Treg-therapy allows mixed chimerism and transplantation tolerance without cytoreductive conditioning. Am J Transplant (2010) 1.36
Transplantation tolerance through mixed chimerism. Nat Rev Nephrol (2010) 1.17
Immuno-intervention for the induction of transplantation tolerance through mixed chimerism. Semin Immunol (2011) 1.12
CTLA-4 on alloreactive CD4 T cells interacts with recipient CD80/86 to promote tolerance. Blood (2009) 1.04
Induction of tolerance through mixed chimerism. Cold Spring Harb Perspect Med (2014) 0.97
B cells and transplantation tolerance. Nat Rev Nephrol (2010) 0.97
T-regulatory cell treatment prevents chronic rejection of heart allografts in a murine mixed chimerism model. J Heart Lung Transplant (2013) 0.96
Translating tolerogenic therapies to the clinic - where do we stand? Front Immunol (2012) 0.91
Costimulatory pathways in transplantation. Semin Immunol (2011) 0.90
CTLA4Ig promotes the induction of hematopoietic chimerism and tolerance independently of Indoleamine-2,3-dioxygenase. Transplantation (2007) 0.90
Hematopoietic cell transplantation for tolerance induction: animal models to clinical trials. Transplantation (2009) 0.89
Hematopoietic chimerism and transplantation tolerance: a role for regulatory T cells. Front Immunol (2011) 0.83
Mixed chimerism and split tolerance: mechanisms and clinical correlations. Chimerism (2012) 0.83
Manipulating the immune system for anti-tumor responses and transplant tolerance via mixed hematopoietic chimerism. Immunol Rev (2008) 0.83
Spontaneous allograft tolerance in B7-deficient mice independent of preexisting endogenous CD4+CD25+ regulatory T-cells. Transplantation (2007) 0.80
Rapamycin generates graft-homing murine suppressor CD8(+) T cells that confer donor-specific graft protection. Cell Transplant (2011) 0.79
Depletion of foxp3(+) T cells abrogates tolerance of skin and heart allografts in murine mixed chimeras without the loss of mixed chimerism. Am J Transplant (2014) 0.79
Adipose-derived stromal cells promote allograft tolerance induction. Stem Cells Transl Med (2014) 0.78
Tolerance induction strategies in vascularized composite allotransplantation: mixed chimerism and novel developments. Clin Dev Immunol (2012) 0.77
Alloreactive Regulatory T Cells Allow the Generation of Mixed Chimerism and Transplant Tolerance. Front Immunol (2015) 0.76
Immune tolerance in recipients of combined haploidentical bone marrow and kidney transplantation. Bone Marrow Transplant (2015) 0.76
Differential sensitivity of regulatory and effector T cells to cell death: a prerequisite for transplant tolerance. Front Immunol (2015) 0.75
Incomplete clonal deletion as prerequisite for tissue-specific minor antigen tolerization. JCI Insight (2016) 0.75
Application of allogeneic bone marrow cells in view of residual alloreactivity: sirolimus but not cyclosporine evolves tolerogenic properties. PLoS One (2015) 0.75
Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells. Nature (2006) 46.36
Adenosine generation catalyzed by CD39 and CD73 expressed on regulatory T cells mediates immune suppression. J Exp Med (2007) 10.00
The Tim-3 ligand galectin-9 negatively regulates T helper type 1 immunity. Nat Immunol (2005) 7.80
Myelin-specific regulatory T cells accumulate in the CNS but fail to control autoimmune inflammation. Nat Med (2007) 7.73
HLA-mismatched renal transplantation without maintenance immunosuppression. N Engl J Med (2008) 7.42
IL-4 inhibits TGF-beta-induced Foxp3+ T cells and, together with TGF-beta, generates IL-9+ IL-10+ Foxp3(-) effector T cells. Nat Immunol (2008) 6.41
Mast cells are essential intermediaries in regulatory T-cell tolerance. Nature (2006) 5.49
Tim-3 inhibits T helper type 1-mediated auto- and alloimmune responses and promotes immunological tolerance. Nat Immunol (2003) 5.07
Interaction of Tim-3 and Tim-3 ligand regulates T helper type 1 responses and induction of peripheral tolerance. Nat Immunol (2003) 4.66
Cutting edge: CD28 controls peripheral homeostasis of CD4+CD25+ regulatory T cells. J Immunol (2003) 3.86
Distribution and compartmentalization of human circulating and tissue-resident memory T cell subsets. Immunity (2012) 3.21
TIM-4 is the ligand for TIM-1, and the TIM-1-TIM-4 interaction regulates T cell proliferation. Nat Immunol (2005) 3.00
Favorably tipping the balance between cytopathic and regulatory T cells to create transplantation tolerance. Immunity (2003) 2.80
Induction of robust cellular and humoral virus-specific adaptive immune responses in human immunodeficiency virus-infected humanized BLT mice. J Virol (2009) 2.70
Clinical trial of islet xenotransplantation in Mexico. Xenotransplantation (2006) 2.51
CD154 blockade for induction of mixed chimerism and prolonged renal allograft survival in nonhuman primates. Am J Transplant (2004) 2.45
In vivo imaging of Treg cells providing immune privilege to the haematopoietic stem-cell niche. Nature (2011) 2.44
T-regulatory cells shift from a protective anti-inflammatory to a cancer-promoting proinflammatory phenotype in polyposis. Cancer Res (2009) 2.43
Clinical islet transplantation: advances and immunological challenges. Nat Rev Immunol (2004) 2.40
Organ transplantation--how much of the promise has been realized? Nat Med (2005) 2.26
Transient and Persistent Acute Kidney Injury and the Risk of Hospital Mortality in Critically Ill Patients: Results of a Multicenter Cohort Study. Crit Care Med (2015) 2.16
TIM-3 is expressed on activated human CD4+ T cells and regulates Th1 and Th17 cytokines. Eur J Immunol (2009) 2.00
The use of the Oxford classification of IgA nephropathy to predict renal survival. Clin J Am Soc Nephrol (2011) 1.99
An inflammatory checkpoint regulates recruitment of graft-versus-host reactive T cells to peripheral tissues. J Exp Med (2006) 1.94
Tolerance induction in clinical transplantation. Transpl Immunol (2004) 1.90
Tolerance and cancer: mechanisms of tumor evasion and strategies for breaking tolerance. J Clin Oncol (2004) 1.87
Curative and beta cell regenerative effects of alpha1-antitrypsin treatment in autoimmune diabetic NOD mice. Proc Natl Acad Sci U S A (2008) 1.83
Predicting the risk for dialysis or death in IgA nephropathy. J Am Soc Nephrol (2011) 1.83
Upregulation of miR-142-3p in peripheral blood mononuclear cells of operationally tolerant patients with a renal transplant. J Am Soc Nephrol (2012) 1.81
Xenotransplantation: current status and a perspective on the future. Nat Rev Immunol (2007) 1.80
Role for CD47-SIRPalpha signaling in xenograft rejection by macrophages. Proc Natl Acad Sci U S A (2007) 1.80
Induction of kidney allograft tolerance after transient lymphohematopoietic chimerism in patients with multiple myeloma and end-stage renal disease. Transplantation (2002) 1.75
Errors induced by indexing glomerular filtration rate for body surface area: reductio ad absurdum. Nephrol Dial Transplant (2009) 1.74
IL-33 expands suppressive CD11b+ Gr-1(int) and regulatory T cells, including ST2L+ Foxp3+ cells, and mediates regulatory T cell-dependent promotion of cardiac allograft survival. J Immunol (2011) 1.72
Reciprocal generation of Th1/Th17 and T(reg) cells by B1 and B2 B cells. Eur J Immunol (2007) 1.70
CD39 and control of cellular immune responses. Purinergic Signal (2007) 1.68
Immunostimulatory Tim-1-specific antibody deprograms Tregs and prevents transplant tolerance in mice. J Clin Invest (2008) 1.66
Local irradiation enhances congenic donor pluripotent hematopoietic stem cell engraftment similarly in irradiated and nonirradiated sites. Blood (2003) 1.64
Tim-2 regulates T helper type 2 responses and autoimmunity. J Exp Med (2005) 1.63
In vivo tracking of 'color-coded' effector, natural and induced regulatory T cells in the allograft response. Nat Med (2010) 1.63
Antigen-specific human T-cell responses and T cell-dependent production of human antibodies in a humanized mouse model. Blood (2008) 1.60
TIM-4 expressed on APCs induces T cell expansion and survival. J Immunol (2008) 1.58
Role of the programmed death-1 pathway in regulation of alloimmune responses in vivo. J Immunol (2005) 1.58
Mechanisms of donor-specific transfusion tolerance: preemptive induction of clonal T-cell exhaustion via indirect presentation. Blood (2003) 1.57
Cystatin C: current position and future prospects. Clin Chem Lab Med (2008) 1.51
Tracking the immunoregulatory mechanisms active during allograft tolerance. J Immunol (2002) 1.50
The influence of immunosuppressive drugs on tolerance induction through bone marrow transplantation with costimulation blockade. Blood (2002) 1.49
Estimating glomerular filtration rate in Asian subjects: where do we stand? Kidney Int (2011) 1.47
Xenogeneic thymus transplantation in a pig-to-baboon model. Transplantation (2003) 1.47
Ethanol lock and risk of hemodialysis catheter infection in critically ill patients. A randomized controlled trial. Am J Respir Crit Care Med (2015) 1.44
Attenuation of phagocytosis of xenogeneic cells by manipulating CD47. Blood (2006) 1.44
Mechanisms underlying blockade of allograft acceptance by TLR ligands. J Immunol (2008) 1.41
Autoantibodies targeting galactose-deficient IgA1 associate with progression of IgA nephropathy. J Am Soc Nephrol (2012) 1.40
Corticosteroid-free immunosuppression with tacrolimus, mycophenolate mofetil, and daclizumab induction in renal transplantation. Transplantation (2005) 1.39
Immunologic basis of graft rejection and tolerance following transplantation of liver or other solid organs. Gastroenterology (2010) 1.39
Stimulating PD-1-negative signals concurrent with blocking CD154 co-stimulation induces long-term islet allograft survival. Transplantation (2003) 1.38
The role of antigen-presenting cells in triggering graft-versus-host disease and graft-versus-leukemia. Blood (2007) 1.37
Nonmyeloablative haploidentical stem-cell transplantation using anti-CD2 monoclonal antibody (MEDI-507)-based conditioning for refractory hematologic malignancies. Transplantation (2003) 1.36
Exogenous IFN-gamma ex vivo shapes the alloreactive T-cell repertoire by inhibition of Th17 responses and generation of functional Foxp3+ regulatory T cells. Eur J Immunol (2008) 1.36
Impact of prophylactic donor leukocyte infusions on mixed chimerism, graft-versus-host disease, and antitumor response in patients with advanced hematologic malignancies treated with nonmyeloablative conditioning and allogeneic bone marrow transplantation. Biol Blood Marrow Transplant (2003) 1.35
Modification of adverse inflammation is required to cure new-onset type 1 diabetic hosts. Proc Natl Acad Sci U S A (2007) 1.35
Peritoneal cavity B cells are precursors of splenic IgM natural antibody-producing cells. J Immunol (2003) 1.34
Treg versus Th17 lymphocyte lineages are cross-regulated by LIF versus IL-6. Cell Cycle (2009) 1.34
Targeting IL-15 receptor-bearing cells with an antagonist mutant IL-15/Fc protein prevents disease development and progression in murine collagen-induced arthritis. J Immunol (2004) 1.33
HLA-mismatched renal transplantation without maintenance immunosuppression. N Engl J Med (2013) 1.29
Mechanisms of transplant tolerance induction using costimulatory blockade. Curr Opin Immunol (2002) 1.28
A model for personalized in vivo analysis of human immune responsiveness. Sci Transl Med (2012) 1.27
Mixed chimerism, lymphocyte recovery, and evidence for early donor-specific unresponsiveness in patients receiving combined kidney and bone marrow transplantation to induce tolerance. Transplantation (2010) 1.25
Donor-derived interferon gamma separates graft-versus-leukemia effects and graft-versus-host disease induced by donor CD8 T cells. Blood (2002) 1.24
Anti-tumour response despite loss of donor chimaerism in patients treated with non-myeloablative conditioning and allogeneic stem cell transplantation. Br J Haematol (2005) 1.22
Translational studies in hematopoietic cell transplantation: treatment of hematologic malignancies as a stepping stone to tolerance induction. Semin Immunol (2011) 1.21
Emerging concepts in haematopoietic cell transplantation. Nat Rev Immunol (2012) 1.20
CD154 on the surface of CD4+CD25+ regulatory T cells contributes to skin transplant tolerance. Transplantation (2003) 1.19
Critical role of OX40 in CD28 and CD154-independent rejection. J Immunol (2004) 1.19
Induction of human T-cell tolerance to porcine xenoantigens through mixed hematopoietic chimerism. Blood (2004) 1.19
Peripheral deletional tolerance of alloreactive CD8 but not CD4 T cells is dependent on the PD-1/PD-L1 pathway. Blood (2008) 1.19
Specificity of CD4+CD25+ regulatory T cell function in alloimmunity. J Immunol (2006) 1.19