Published in Diabetes on January 19, 2010
Type 1 diabetes. Lancet (2013) 3.45
Potent induction immunotherapy promotes long-term insulin independence after islet transplantation in type 1 diabetes. Am J Transplant (2012) 2.12
Stopping type 1 diabetes: attempts to prevent or cure type 1 diabetes in man. Diabetes (2011) 1.77
Vaccination against type 1 diabetes. J Intern Med (2011) 1.46
MHC class II tetramers. J Immunol (2012) 1.45
Update on islet transplantation. Cold Spring Harb Perspect Med (2012) 1.40
High-resolution, noninvasive longitudinal live imaging of immune responses. Proc Natl Acad Sci U S A (2011) 1.22
Long-term metabolic and immunological follow-up of nonimmunosuppressed patients with type 1 diabetes treated with microencapsulated islet allografts: four cases. Diabetes Care (2011) 1.08
Increased frequencies of myelin oligodendrocyte glycoprotein/MHC class II-binding CD4 cells in patients with multiple sclerosis. J Immunol (2011) 1.00
Alloantibody and autoantibody monitoring predicts islet transplantation outcome in human type 1 diabetes. Diabetes (2012) 0.99
The IL-2/IL-2R system: from basic science to therapeutic applications to enhance immune regulation. Immunol Res (2013) 0.94
New insight on human type 1 diabetes biology: nPOD and nPOD-transplantation. Curr Diab Rep (2014) 0.93
T cells in the control of organ-specific autoimmunity. J Clin Invest (2015) 0.93
Current and future immunomodulation strategies to restore tolerance in autoimmune diseases. Cold Spring Harb Perspect Biol (2012) 0.91
Antibodies reactive to non-HLA antigens in transplant glomerulopathy. J Am Soc Nephrol (2011) 0.91
Advancing animal models of human type 1 diabetes by engraftment of functional human tissues in immunodeficient mice. Cold Spring Harb Perspect Med (2012) 0.91
Juvenile Diabetes Research Foundation: mission, strategy, and priorities. Diabetes (2012) 0.90
Prevention of autoimmune diabetes and induction of β-cell proliferation in NOD mice by hyperbaric oxygen therapy. Diabetes (2012) 0.90
T cell recognition of autoantigens in human type 1 diabetes: clinical perspectives. Clin Dev Immunol (2011) 0.89
Analysis of self-antigen specificity of islet-infiltrating T cells from human donors with type 1 diabetes. Nat Med (2016) 0.89
Recurrence of autoimmunity following pancreas transplantation. Curr Diab Rep (2011) 0.88
Toward beta cell replacement for diabetes. EMBO J (2015) 0.86
Immune responses against islet allografts during tapering of immunosuppression--a pilot study in 5 subjects. Clin Exp Immunol (2012) 0.86
Reversal of diabetes in mice with a bioengineered islet implant incorporating a type I collagen hydrogel and sustained release of vascular endothelial growth factor. Cell Transplant (2012) 0.85
Antigen-specific prevention of type 1 diabetes in NOD mice is ameliorated by OX40 agonist treatment. J Autoimmun (2011) 0.85
IL-7 uniquely maintains FoxP3(+) adaptive Treg cells that reverse diabetes in NOD mice via integrin-β7-dependent localization. J Autoimmun (2011) 0.85
Anti-cytokine therapies in T1D: Concepts and strategies. Clin Immunol (2013) 0.84
Harnessing memory adaptive regulatory T cells to control autoimmunity in type 1 diabetes. J Mol Cell Biol (2011) 0.84
Challenges in the pursuit of immune tolerance. Immunol Rev (2011) 0.83
Immune antibody monitoring predicts outcome in islet transplantation. Diabetes (2013) 0.81
Fetal pancreas transplants are dependent on prolactin for their development and prevent type 1 diabetes in syngeneic but not allogeneic mice. Diabetes (2013) 0.81
Investigating the role of T-cell avidity and killing efficacy in relation to type 1 diabetes prediction. PLoS One (2011) 0.81
Recurrence of autoimmunity in pancreas transplant patients: research update. Diabetes Manag (Lond) (2011) 0.81
Advantage of rapamycin over mycophenolate mofetil when used with tacrolimus for simultaneous pancreas kidney transplants: randomized, single-center trial at 10 years. Am J Transplant (2012) 0.80
Biomarkers in type 1 diabetes: application to the clinical trial setting. Curr Opin Endocrinol Diabetes Obes (2014) 0.80
Re-engineering islet cell transplantation. Pharmacol Res (2015) 0.79
Homeostatic T cell proliferation after islet transplantation. Clin Dev Immunol (2013) 0.79
Report from IPITA-TTS Opinion Leaders Meeting on the Future of β-Cell Replacement. Transplantation (2016) 0.79
Predictive models of type 1 diabetes progression: understanding T-cell cycles and their implications on autoantibody release. PLoS One (2014) 0.78
Obstacles and opportunities for targeting the effector T cell response in type 1 diabetes. J Autoimmun (2016) 0.78
Kidney Versus Islet Allograft Survival After Induction of Mixed Chimerism With Combined Donor Bone Marrow Transplantation. Cell Transplant (2015) 0.77
Stem cell treatment for type 1 diabetes. Front Cell Dev Biol (2014) 0.77
IL-10 induction from implants delivering pancreatic islets and hyaluronan. J Diabetes Res (2013) 0.76
Adoptive T Regulatory Cell Therapy for Tolerance Induction. Curr Transplant Rep (2015) 0.76
Narrowing in on the anti-β cell-specific T cells: looking 'where the action is'. Curr Opin Endocrinol Diabetes Obes (2017) 0.75
Insulitis in the pathogenesis of type 1 diabetes. Pediatr Diabetes (2016) 0.75
The cardinal features of recurrent autoimmunity in simultaneous pancreas-kidney transplant recipients. Curr Diab Rep (2010) 0.75
Autoimmune diabetes recurrence should be routinely monitored after pancreas transplantation. World J Transplant (2014) 0.75
Can We Repurpose FDA-Approved Alefacept to Diminish the HIV Reservoir? Immunotherapy (Los Angel) (2015) 0.75
Autologous and Allogenous Antibodies in Lung and Islet Cell Transplantation. Front Immunol (2016) 0.75
B cell-targeted immunotherapy for type 1 diabetes: What can make it work? Discov Med (2016) 0.75
Production of primary human CD4⁺ T cell lines and clones. Methods Mol Biol (2013) 0.75
Combination of an Antigen-Specific Therapy and an Immunomodulatory Treatment to Simultaneous Block Recurrent Autoimmunity and Alloreactivity in Non-Obese Diabetic Mice. PLoS One (2015) 0.75
Tissue distribution and clonal diversity of the T and B cell repertoire in type 1 diabetes. JCI Insight (2016) 0.75
Risk Factors for Type 1 Diabetes Recurrence in Immunosuppressed Recipients of Simultaneous Pancreas-Kidney Transplants. Am J Transplant (2015) 0.75
Serum Cytokines as Biomarkers in Islet Cell Transplantation for Type 1 Diabetes. PLoS One (2016) 0.75
Characterization of the autoimmune response against the nerve tissue S100β in patients with type 1 diabetes. Clin Exp Immunol (2015) 0.75
Proteomic profiling of human islets collected from frozen pancreata using laser capture microdissection. J Proteomics (2016) 0.75
APC-targeted proinsulin expression inactivates insulin-specific memory CD8(+) T cells in NOD mice. Immunol Cell Biol (2017) 0.75
Autoreactive T cells in type 1 diabetes. J Clin Invest (2017) 0.75
International trial of the Edmonton protocol for islet transplantation. N Engl J Med (2006) 13.43
Insulin needs after CD3-antibody therapy in new-onset type 1 diabetes. N Engl J Med (2005) 10.16
Anti-CD3 monoclonal antibody in new-onset type 1 diabetes mellitus. N Engl J Med (2002) 8.84
The cation efflux transporter ZnT8 (Slc30A8) is a major autoantigen in human type 1 diabetes. Proc Natl Acad Sci U S A (2007) 6.44
Type I diabetes mellitus. A chronic autoimmune disease. N Engl J Med (1986) 6.11
The unique cytoarchitecture of human pancreatic islets has implications for islet cell function. Proc Natl Acad Sci U S A (2006) 5.41
Assessment of human pancreatic islet architecture and composition by laser scanning confocal microscopy. J Histochem Cytochem (2005) 4.40
The prevalence of enteroviral capsid protein vp1 immunostaining in pancreatic islets in human type 1 diabetes. Diabetologia (2009) 3.70
Coxsackie B4 virus infection of beta cells and natural killer cell insulitis in recent-onset type 1 diabetic patients. Proc Natl Acad Sci U S A (2007) 3.11
Diabetes Antibody Standardization Program: first assay proficiency evaluation. Diabetes (2003) 3.09
Anti-CD3 and nasal proinsulin combination therapy enhances remission from recent-onset autoimmune diabetes by inducing Tregs. J Clin Invest (2006) 2.73
Autoreactive CD8 T cells associated with beta cell destruction in type 1 diabetes. Proc Natl Acad Sci U S A (2005) 2.70
Translational mini-review series on type 1 diabetes: Systematic analysis of T cell epitopes in autoimmune diabetes. Clin Exp Immunol (2007) 2.28
The frequency and immunodominance of islet-specific CD8+ T-cell responses change after type 1 diabetes diagnosis and treatment. Diabetes (2008) 2.04
Detection of GAD65-specific T-cells by major histocompatibility complex class II tetramers in type 1 diabetic patients and at-risk subjects. Diabetes (2002) 2.01
Translational mini-review series on type 1 diabetes: Immune-based therapeutic approaches for type 1 diabetes. Clin Exp Immunol (2007) 1.86
Recurrent diabetes mellitus in the pancreas iso- and allograft. A light and electron microscopic and immunohistochemical analysis of four cases. Lab Invest (1985) 1.80
Islet transplantation in patients with autoimmune diabetes induces homeostatic cytokines that expand autoreactive memory T cells. J Clin Invest (2008) 1.73
A comprehensive guide to antibody and T-cell responses in type 1 diabetes. Tissue Antigens (2003) 1.71
Recurrence of autoimmune diabetes mellitus in recipients of cadaveric pancreatic grafts. N Engl J Med (1996) 1.70
Cellular islet autoimmunity associates with clinical outcome of islet cell transplantation. PLoS One (2008) 1.67
Pancreas transplantation. Lancet (2009) 1.58
Evidence for in vivo primed and expanded autoreactive T cells as a specific feature of patients with type 1 diabetes. J Immunol (2007) 1.49
Heme oxygenase-1 induction in islet cells results in protection from apoptosis and improved in vivo function after transplantation. Diabetes (2001) 1.43
GAD65-specific CD4+ T-cells with high antigen avidity are prevalent in peripheral blood of patients with type 1 diabetes. Diabetes (2004) 1.41
Identification of novel IGRP epitopes targeted in type 1 diabetes patients. Clin Immunol (2008) 1.38
Function and regulation of MHC class II molecules in T-lymphocytes: of mice and men. Hum Immunol (2004) 1.27
Identification of Novel HLA-A*0201-restricted epitopes in recent-onset type 1 diabetic subjects and antibody-positive relatives. Diabetes (2006) 1.21
Pancreas transplantation. An immunohistologic and histopathologic examination of 100 grafts. Am J Pathol (1987) 1.21
Recognition of HLA class I-restricted beta-cell epitopes in type 1 diabetes. Diabetes (2006) 1.20
Twin-to-twin pancreas transplantation: reversal and reenactment of the pathogenesis of type I diabetes. Trans Assoc Am Physicians (1984) 1.15
Recurrence of disease in pancreas transplants. Diabetes (1989) 1.14
Recurrence of autoreactive antigen-specific CD4+ T cells in autoimmune diabetes after pancreas transplantation. Clin Immunol (2008) 1.14
Can we learn from viruses how to prevent type 1 diabetes?: the role of viral infections in the pathogenesis of type 1 diabetes and the development of novel combination therapies. Diabetes (2009) 1.13
A unique T cell subset described as CD4loCD40+ T cells (TCD40) in human type 1 diabetes. Clin Immunol (2007) 1.11
Dynamic changes in pancreatic endocrine cell abundance, distribution, and function in antigen-induced and spontaneous autoimmune diabetes. Diabetes (2009) 1.10
Modulation of humoral islet autoimmunity by pancreas allotransplantation influences allograft outcome in patients with type 1 diabetes. Diabetes (2000) 1.07
Allorecognition and the alloresponse: clinical implications. Tissue Antigens (2007) 1.05
Characterization of T lymphocytes infiltrating human pancreas allograft affected by isletitis and recurrent diabetes. Diabetes (1992) 0.99
Insulin protein and proliferation in ductal cells in the transplanted pancreas of patients with type 1 diabetes and recurrence of autoimmunity. Diabetologia (2008) 0.97
Evidence of recurrent type I diabetes following HLA-mismatched pancreas transplantation. Diabetes Metab (2000) 0.96
MHC-mismatched islet allografts are vulnerable to autoimmune recognition in vivo. J Immunol (2005) 0.89
Serological markers of recurrent beta cell destruction in diabetic patients undergoing pancreatic transplantation. Transplantation (2000) 0.89
Ontogeny and tissue distribution of human GAD expression. Diabetes (1996) 0.86
Recurrence of immunological markers for type 1 (insulin-dependent) diabetes mellitus in immunosuppressed patients after pancreas transplantation. Transplantation (1998) 0.85
Islet cell autoimmunity in type I diabetic patients after HLA-mismatched pancreas transplantation. Diabetes (1989) 0.84
Islet cell antibodies, but not glutamic acid decarboxylase antibodies, are decreased by plasmapheresis in patients with newly diagnosed insulin-dependent diabetes mellitus. J Clin Endocrinol Metab (1994) 0.82
Immunoregulation by cytokines in autoimmune diabetes. Adv Exp Med Biol (2003) 0.81
International trial of the Edmonton protocol for islet transplantation. N Engl J Med (2006) 13.43
Projection of an immunological self shadow within the thymus by the aire protein. Science (2002) 12.15
Circulating urokinase receptor as a cause of focal segmental glomerulosclerosis. Nat Med (2011) 6.35
Abatacept in B7-1-positive proteinuric kidney disease. N Engl J Med (2013) 5.62
The unique cytoarchitecture of human pancreatic islets has implications for islet cell function. Proc Natl Acad Sci U S A (2006) 5.41
The cellular mechanism of Aire control of T cell tolerance. Immunity (2005) 4.74
Angiotensin II causes hypertension and cardiac hypertrophy through its receptors in the kidney. Proc Natl Acad Sci U S A (2006) 4.10
Expanded T cells from pancreatic lymph nodes of type 1 diabetic subjects recognize an insulin epitope. Nature (2005) 3.62
Loss of ARNT/HIF1beta mediates altered gene expression and pancreatic-islet dysfunction in human type 2 diabetes. Cell (2005) 3.52
Narcolepsy is strongly associated with the T-cell receptor alpha locus. Nat Genet (2009) 3.33
Rituximab targets podocytes in recurrent focal segmental glomerulosclerosis. Sci Transl Med (2011) 3.19
Genetics of type 1A diabetes. N Engl J Med (2009) 3.18
Kv1.3 channels are a therapeutic target for T cell-mediated autoimmune diseases. Proc Natl Acad Sci U S A (2006) 3.13
Islet transplantation in type 1 diabetes mellitus using cultured islets and steroid-free immunosuppression: Miami experience. Am J Transplant (2005) 3.07
IL-17 enhances the net angiogenic activity and in vivo growth of human non-small cell lung cancer in SCID mice through promoting CXCR-2-dependent angiogenesis. J Immunol (2005) 3.02
Induction therapy with autologous mesenchymal stem cells in living-related kidney transplants: a randomized controlled trial. JAMA (2012) 2.85
A novel method for the assessment of cellular composition and beta-cell viability in human islet preparations. Am J Transplant (2005) 2.74
De novo generation of antigen-specific CD4+CD25+ regulatory T cells from human CD4+CD25- cells. Proc Natl Acad Sci U S A (2005) 2.57
Transplantation of cultured islets from two-layer preserved pancreases in type 1 diabetes with anti-CD3 antibody. Am J Transplant (2004) 2.55
Innervation patterns of autonomic axons in the human endocrine pancreas. Cell Metab (2011) 2.48
Noninvasive in vivo imaging of pancreatic islet cell biology. Nat Med (2008) 2.41
Prediction and pathogenesis in type 1 diabetes. Immunity (2010) 2.26
When and why portal vein thrombosis matters in liver transplantation: a critical audit of 174 cases. Ann Surg (2014) 2.23
Systems scale interactive exploration reveals quantitative and qualitative differences in response to influenza and pneumococcal vaccines. Immunity (2013) 2.08
Rescue purification maximizes the use of human islet preparations for transplantation. Am J Transplant (2005) 2.04
Diagnostic testing of vitrectomy specimens. Am J Ophthalmol (2005) 2.03
Glutamate is a positive autocrine signal for glucagon release. Cell Metab (2008) 2.01
Detection of GAD65-specific T-cells by major histocompatibility complex class II tetramers in type 1 diabetic patients and at-risk subjects. Diabetes (2002) 2.01
Prognostic impact of the 2009 UICC/AJCC TNM staging system for renal cell carcinoma with venous extension. Eur Urol (2010) 1.99
Surgical techniques for treating a renal neoplasm invading the inferior vena cava. J Urol (2003) 1.98
A role for angiotensin II type 1 receptors on bone marrow-derived cells in the pathogenesis of angiotensin II-dependent hypertension. Hypertension (2009) 1.94
Multipotent stem/progenitor cells in human biliary tree give rise to hepatocytes, cholangiocytes, and pancreatic islets. Hepatology (2011) 1.94
Memory B cells without somatic hypermutation are generated from Bcl6-deficient B cells. Immunity (2002) 1.94
Donor-specific B-cell tolerance after ABO-incompatible infant heart transplantation. Nat Med (2004) 1.92
Podocyte foot process effacement in postreperfusion allograft biopsies correlates with early recurrence of proteinuria in focal segmental glomerulosclerosis. Transplantation (2012) 1.89
A novel image-guided surgery of hepatocellular carcinoma by indocyanine green fluorescence imaging navigation. J Surg Oncol (2009) 1.85
The use of exenatide in islet transplant recipients with chronic allograft dysfunction: safety, efficacy, and metabolic effects. Transplantation (2008) 1.83
A novel role for type 1 angiotensin receptors on T lymphocytes to limit target organ damage in hypertension. Circ Res (2012) 1.79
Stopping type 1 diabetes: attempts to prevent or cure type 1 diabetes in man. Diabetes (2011) 1.77
Lymphocyte responses exacerbate angiotensin II-dependent hypertension. Am J Physiol Regul Integr Comp Physiol (2010) 1.76
Cyclodextrin protects podocytes in diabetic kidney disease. Diabetes (2013) 1.71
Stimulation of lymphocyte responses by angiotensin II promotes kidney injury in hypertension. Am J Physiol Renal Physiol (2008) 1.71
Network for Pancreatic Organ Donors with Diabetes (nPOD): developing a tissue biobank for type 1 diabetes. Diabetes Metab Res Rev (2012) 1.68
Evaluation of intravenous immunoglobulin as an agent to lower allosensitization and improve transplantation in highly sensitized adult patients with end-stage renal disease: report of the NIH IG02 trial. J Am Soc Nephrol (2004) 1.68
Antibiotic-refractory Lyme arthritis is associated with HLA-DR molecules that bind a Borrelia burgdorferi peptide. J Exp Med (2006) 1.67
Long-term insulin independence and improvement in insulin secretion after supplemental islet infusion under exenatide and etanercept. Transplantation (2008) 1.66
Common variants in P2RY11 are associated with narcolepsy. Nat Genet (2010) 1.65
Ultra-sensitive detection of rare T cell clones. J Immunol Methods (2011) 1.64
Alpha cells secrete acetylcholine as a non-neuronal paracrine signal priming beta cell function in humans. Nat Med (2011) 1.62
Composite tissue allotransplantation: classification of clinical acute skin rejection. Transplantation (2006) 1.61
Heterotopic uterus transplantation in a swine model. Transplantation (2009) 1.59
Successful prospective prediction of type 1 diabetes in schoolchildren through multiple defined autoantibodies: an 8-year follow-up of the Washington State Diabetes Prediction Study. Diabetes Care (2002) 1.59
Evidence for a protective role for adiponectin in osteoarthritis. Biochim Biophys Acta (2006) 1.56
Combined functional and positional gene information for the identification of susceptibility variants in celiac disease. Gastroenterology (2007) 1.56
Islet-specific glucose-6-phosphatase catalytic subunit-related protein-reactive CD4+ T cells in human subjects. J Immunol (2006) 1.55
Association of tumor necrosis factor alpha polymorphism, but not the shared epitope, with increased radiographic progression in a seropositive rheumatoid arthritis inception cohort. Arthritis Rheum (2006) 1.55
The insulin A-chain epitope recognized by human T cells is posttranslationally modified. J Exp Med (2005) 1.55
Quantitative differential expression analysis reveals miR-7 as major islet microRNA. Biochem Biophys Res Commun (2007) 1.54
Transplantation of the abdominal wall. Lancet (2003) 1.51
Small molecule-mediated activation of the integrin CD11b/CD18 reduces inflammatory disease. Sci Signal (2011) 1.51
Immunochemical quantification of free immunoglobulin light chains from an analytical perspective. Clin Chem Lab Med (2006) 1.51
Lost in translation: barriers to implementing clinical immunotherapeutics for autoimmunity. J Exp Med (2005) 1.50
CD2AP in mouse and human podocytes controls a proteolytic program that regulates cytoskeletal structure and cellular survival. J Clin Invest (2011) 1.49
Analysis of T-cell assays to measure autoimmune responses in subjects with type 1 diabetes: results of a blinded controlled study. Diabetes (2006) 1.49
Subretinal transplantation of bone marrow mesenchymal stem cells delays retinal degeneration in the RCS rat model of retinal degeneration. Exp Eye Res (2007) 1.48
Mechanisms of the proteinuria induced by Rho GTPases. Kidney Int (2012) 1.48
The Juvenile Diabetes Research Foundation Network for Pancreatic Organ Donors with Diabetes (nPOD) Program: goals, operational model and emerging findings. Pediatr Diabetes (2013) 1.46
Edmonton's islet success has indeed been replicated elsewhere. Lancet (2003) 1.45
Two decades of pediatric kidney transplantation in a multi-ethnic cohort. Pediatr Transplant (2010) 1.45