Published in Proc Natl Acad Sci U S A on July 08, 2005
Autonomous zinc-finger nuclease pairs for targeted chromosomal deletion. Nucleic Acids Res (2010) 1.92
Computer design of obligate heterodimer meganucleases allows efficient cutting of custom DNA sequences. Nucleic Acids Res (2008) 1.74
Analysis of the human E2 ubiquitin conjugating enzyme protein interaction network. Genome Res (2009) 1.68
Designed tumor necrosis factor-related apoptosis-inducing ligand variants initiating apoptosis exclusively via the DR5 receptor. Proc Natl Acad Sci U S A (2006) 1.45
Computer-aided antibody design. Protein Eng Des Sel (2012) 1.44
Joint annotation of coding and non-coding single nucleotide polymorphisms and mutations in the SNPeffect and PupaSuite databases. Nucleic Acids Res (2007) 1.43
Anthrax lethal factor protease inhibitors: synthesis, SAR, and structure-based 3D QSAR studies. J Med Chem (2006) 1.27
Predicted effects of missense mutations on native-state stability account for phenotypic outcome in phenylketonuria, a paradigm of misfolding diseases. Am J Hum Genet (2007) 1.24
Robust recognition of zinc binding sites in proteins. Protein Sci (2007) 1.23
Molecular basis of engineered meganuclease targeting of the endogenous human RAG1 locus. Nucleic Acids Res (2010) 1.19
Modeling the hydration layer around proteins: HyPred. Biophys J (2010) 1.08
Rapid and efficient cancer cell killing mediated by high-affinity death receptor homotrimerizing TRAIL variants. Cell Death Dis (2010) 1.06
Predicting helix orientation for coiled-coil dimers. Proteins (2008) 1.06
Construction of a stability landscape of the CH3 domain of human IgG1 by combining directed evolution with high throughput sequencing. J Mol Biol (2012) 1.06
Quantifying information transfer by protein domains: analysis of the Fyn SH2 domain structure. BMC Struct Biol (2008) 1.05
Challenges in the computational design of proteins. J R Soc Interface (2009) 1.03
Genome-wide prediction of SH2 domain targets using structural information and the FoldX algorithm. PLoS Comput Biol (2008) 1.02
FlexOracle: predicting flexible hinges by identification of stable domains. BMC Bioinformatics (2007) 1.02
Rapid and accurate prediction and scoring of water molecules in protein binding sites. PLoS One (2012) 1.02
Prediction of the functional class of metal-binding proteins from sequence derived physicochemical properties by support vector machine approach. BMC Bioinformatics (2006) 1.01
FINDSITE-metal: integrating evolutionary information and machine learning for structure-based metal-binding site prediction at the proteome level. Proteins (2010) 1.00
Predicting the Impact of Missense Mutations on Protein-Protein Binding Affinity. J Chem Theory Comput (2014) 0.98
Predicting small ligand binding sites in proteins using backbone structure. Bioinformatics (2008) 0.97
Towards predicting Ca2+-binding sites with different coordination numbers in proteins with atomic resolution. Proteins (2009) 0.96
On human disease-causing amino acid variants: statistical study of sequence and structural patterns. Hum Mutat (2015) 0.93
Drosophila screen connects nuclear transport genes to DPR pathology in c9ALS/FTD. Sci Rep (2016) 0.93
First-step mutations for adaptation at elevated temperature increase capsid stability in a virus. PLoS One (2011) 0.93
Prediction of structures of zinc-binding proteins through explicit modeling of metal coordination geometry. Protein Sci (2010) 0.92
An evolutionary trade-off between protein turnover rate and protein aggregation favors a higher aggregation propensity in fast degrading proteins. PLoS Comput Biol (2011) 0.92
Relationship between protein thermodynamic constraints and variation of evolutionary rates among sites. Phys Biol (2015) 0.92
Predicting nonspecific ion binding using DelPhi. Biophys J (2012) 0.91
Blind prediction of interfacial water positions in CAPRI. Proteins (2013) 0.90
Using structural bioinformatics to investigate the impact of non synonymous SNPs and disease mutations: scope and limitations. BMC Bioinformatics (2009) 0.89
Targeting AML through DR4 with a novel variant of rhTRAIL. J Cell Mol Med (2011) 0.89
Redox biology: computational approaches to the investigation of functional cysteine residues. Antioxid Redox Signal (2011) 0.89
Phosphate binding sites identification in protein structures. Nucleic Acids Res (2010) 0.88
Determining effects of non-synonymous SNPs on protein-protein interactions using supervised and semi-supervised learning. PLoS Comput Biol (2014) 0.88
Prediction of metal ion-binding sites in proteins using the fragment transformation method. PLoS One (2012) 0.88
Stability assessment on a library scale: a rapid method for the evaluation of the commutability and insertion of residues in C-terminal loops of the CH3 domains of IgG1-Fc. Protein Eng Des Sel (2013) 0.87
Rational design of a novel calcium-binding site adjacent to the ligand-binding site on CD2 increases its CD48 affinity. Protein Sci (2008) 0.87
The design and characterization of receptor-selective APRIL variants. J Biol Chem (2012) 0.86
Computational and experimental approaches to reveal the effects of single nucleotide polymorphisms with respect to disease diagnostics. Int J Mol Sci (2014) 0.86
Delivery of sTRAIL variants by MSCs in combination with cytotoxic drug treatment leads to p53-independent enhanced antitumor effects. Cell Death Dis (2013) 0.86
Analysis and prediction of calcium-binding pockets from apo-protein structures exhibiting calcium-induced localized conformational changes. Protein Sci (2010) 0.85
Calciomics: integrative studies of Ca2+-binding proteins and their interactomes in biological systems. Metallomics (2013) 0.84
Mapping Enterovirus A71 Antigenic Determinants from Viral Evolution. J Virol (2015) 0.82
The contribution of coevolving residues to the stability of KDO8P synthase. PLoS One (2011) 0.82
A gatekeeper helix determines the substrate specificity of Sjögren-Larsson Syndrome enzyme fatty aldehyde dehydrogenase. Nat Commun (2014) 0.82
Docking of calcium ions in proteins with flexible side chains and deformable backbones. Eur Biophys J (2009) 0.81
Structural insights into Saccharomyces cerevisiae Msh4-Msh5 complex function using homology modeling. PLoS One (2013) 0.81
Insight into the structure, dynamics and the unfolding property of amylosucrases: implications of rational engineering on thermostability. PLoS One (2012) 0.81
Intra-epidemic evolutionary dynamics of a Dengue virus type 1 population reveal mutant spectra that correlate with disease transmission. Sci Rep (2016) 0.80
Functional validation of hydrophobic adaptation to physiological temperature in the small heat shock protein αA-crystallin. PLoS One (2012) 0.80
Four plant defensins from an indigenous South African Brassicaceae species display divergent activities against two test pathogens despite high sequence similarity in the encoding genes. BMC Res Notes (2011) 0.80
Tumor suppressor properties of the splicing regulatory factor RBM10. RNA Biol (2016) 0.80
Predicting the Effect of Mutations on Protein-Protein Binding Interactions through Structure-Based Interface Profiles. PLoS Comput Biol (2015) 0.80
Theoretical prediction of the binding free energy for mutants of replication protein A. J Mol Model (2011) 0.80
Integration of Diverse Research Methods to Analyze and Engineer Ca-Binding Proteins: From Prediction to Production. Curr Bioinform (2010) 0.79
Metalloproteomics: forward and reverse approaches in metalloprotein structural and functional characterization. Curr Opin Chem Biol (2010) 0.79
Changing folding and binding stability in a viral coat protein: a comparison between substitutions accessible through mutation and those fixed by natural selection. PLoS One (2014) 0.79
Secondary structure preferences of mn (2+) binding sites in bacterial proteins. Adv Bioinformatics (2014) 0.78
Structural propensities of human ubiquitination sites: accessibility, centrality and local conformation. PLoS One (2013) 0.78
An integrative computational framework based on a two-step random forest algorithm improves prediction of zinc-binding sites in proteins. PLoS One (2012) 0.78
Structural Modeling of GR Interactions with the SWI/SNF Chromatin Remodeling Complex and C/EBP. Biophys J (2015) 0.78
A combination of computational and experimental approaches identifies DNA sequence constraints associated with target site binding specificity of the transcription factor CSL. Nucleic Acids Res (2014) 0.77
Empirical estimation of local dielectric constants: Toward atomistic design of collagen mimetic peptides. Biopolymers (2015) 0.77
Improving the anti-toxin abilities of the CMG2-Fc fusion protein with the aid of computational design. PLoS One (2014) 0.77
Estimating affinities of calcium ions to proteins. Adv Appl Bioinform Chem (2010) 0.77
Adaptive Evolution as a Predictor of Species-Specific Innate Immune Response. Mol Biol Evol (2015) 0.77
Selecting vaccine strains for H3N2 human influenza A virus. Meta Gene (2015) 0.77
Reduced polymorphism in domains involved in protein-protein interactions. PLoS One (2012) 0.77
Predicting the disruption by UO2(2+) of a protein-ligand interaction. Protein Sci (2010) 0.76
Predicting Ca2+ -binding sites using refined carbon clusters. Proteins (2012) 0.76
Ion binding to biological macromolecules. Asian J Phys (2014) 0.76
Error-prone pcr-based mutagenesis strategy for rapidly generating high-yield influenza vaccine candidates. Virology (2015) 0.76
Structure-based analysis of A19D, a variant of transthyretin involved in familial amyloid cardiomyopathy. PLoS One (2013) 0.76
Neighborhood properties are important determinants of temperature sensitive mutations. PLoS One (2011) 0.76
Herpes B virus gD interaction with its human receptor--an in silico analysis approach. Theor Biol Med Model (2014) 0.76
Phosphorylation Regulates the Bound Structure of an Intrinsically Disordered Protein: The p53-TAZ2 Case. PLoS One (2016) 0.76
Peptidoglycan recognition protein genes and risk of Parkinson's disease. Mov Disord (2014) 0.76
Initiating a watch list for Ebola virus antibody escape mutations. PeerJ (2016) 0.75
Alpha Helices Are More Robust to Mutations than Beta Strands. PLoS Comput Biol (2016) 0.75
Combinatorial and Computational Approaches to Identify Interactions of Macrophage Colony-stimulating Factor (M-CSF) and Its Receptor c-FMS. J Biol Chem (2015) 0.75
Design of Stable α-Helical Peptides and Thermostable Proteins in Biotechnology and Biomedicine. Acta Naturae (2017) 0.75
A Sco protein among the hypothetical proteins of Bacillus lehensis G1: Its 3D macromolecular structure and association with Cytochrome C Oxidase. BMC Struct Biol (2014) 0.75
Evolutionary interplay between structure, energy and epistasis in the coat protein of the ϕX174 phage family. J R Soc Interface (2017) 0.75
Prediction of stability changes upon mutation in an icosahedral capsid. Proteins (2015) 0.75
Waterdock 2.0: Water placement prediction for Holo-structures with a pymol plugin. PLoS One (2017) 0.75
Structural Determinants of Sleeping Beauty Transposase Activity. Mol Ther (2016) 0.75
Is it possible to stabilize a thermophilic protein further using sequences and structures of mesophilic proteins: a theoretical case study concerning DgAS. Theor Biol Med Model (2013) 0.75
Accelerated simulation of evolutionary trajectories in origin-fixation models. J R Soc Interface (2017) 0.75
SIRT6 Is a Positive Regulator of Aldose Reductase Expression in U937 and HeLa cells under Osmotic Stress: In Vitro and In Silico Insights. PLoS One (2016) 0.75
Recurrent structural motifs in non-homologous protein structures. Int J Mol Sci (2013) 0.75
Molecular dynamics simulation of the interactions between EHD1 EH domain and multiple peptides. J Zhejiang Univ Sci B (2015) 0.75
Identification and characterization of wheat drought-responsive MYB transcription factors involved in the regulation of cuticle biosynthesis. J Exp Bot (2016) 0.75
Parallel Mutations Result in a Wide Range of Cooperation and Community Consequences in a Two-Species Bacterial Consortium. PLoS One (2016) 0.75
Modeling intracellular signaling underlying striatal function in health and disease. Prog Mol Biol Transl Sci (2014) 0.75
Alternative evolutionary histories in the sequence space of an ancient protein. Nature (2017) 0.75
Novel compound heterozygous mutations in the GPR98 (USH2C) gene identified by whole exome sequencing in a Moroccan deaf family. Mol Biol Rep (2017) 0.75
Predicting changes in the stability of proteins and protein complexes: a study of more than 1000 mutations. J Mol Biol (2002) 9.74
The FoldX web server: an online force field. Nucleic Acids Res (2005) 6.30
Transition metal speciation in the cell: insights from the chemistry of metal ion receptors. Science (2003) 5.12
Recent advances in the development and application of implicit solvent models in biomolecule simulations. Curr Opin Struct Biol (2004) 4.46
Improving implicit solvent simulations: a Poisson-centric view. Curr Opin Struct Biol (2005) 3.38
Protein-DNA interactions: A structural analysis. J Mol Biol (1999) 3.38
Calmodulin structure refined at 1.7 A resolution. J Mol Biol (1992) 3.25
Effective energy functions for protein structure prediction. Curr Opin Struct Biol (2000) 2.92
Structure of native and apo carbonic anhydrase II and structure of some of its anion-ligand complexes. J Mol Biol (1992) 2.70
SNPeffect: a database mapping molecular phenotypic effects of human non-synonymous coding SNPs. Nucleic Acids Res (2005) 2.69
Structural aspects of metal liganding to functional groups in proteins. Adv Protein Chem (1991) 2.57
Where metal ions bind in proteins. Proc Natl Acad Sci U S A (1990) 2.56
An efficient hybrid explicit/implicit solvent method for biomolecular simulations. J Comput Chem (2004) 2.40
Implicit solvation based on generalized Born theory in different dielectric environments. J Chem Phys (2004) 2.00
Engineering novel metalloproteins: design of metal-binding sites into native protein scaffolds. Chem Rev (2001) 1.76
A "solvated rotamer" approach to modeling water-mediated hydrogen bonds at protein-protein interfaces. Proteins (2005) 1.62
Iron and copper transport in yeast and its relevance to human disease. Trends Biochem Sci (1998) 1.57
Recognizing protein binding sites using statistical descriptions of their 3D environments. Pac Symp Biocomput (1998) 1.57
Predicting the rate enhancement of protein complex formation from the electrostatic energy of interaction. J Mol Biol (1999) 1.53
Predicting Ca(2+)-binding sites in proteins. Proc Natl Acad Sci U S A (1994) 1.51
The SH3-fold family: experimental evidence and prediction of variations in the folding pathways. J Mol Biol (2000) 1.45
A detailed thermodynamic analysis of ras/effector complex interfaces. J Mol Biol (2004) 1.42
Novel metal-binding proteins by design. Nat Struct Biol (1995) 1.41
Energy estimation in protein design. Curr Opin Struct Biol (2002) 1.39
Local water bridges and protein conformational stability. Protein Sci (1999) 1.32
Determinants that govern high-affinity calcium binding. Adv Second Messenger Phosphoprotein Res (1995) 1.30
Calculation of mutational free energy changes in transition states for protein folding. Biophys J (2003) 1.27
Design of a calcium-binding protein with desired structure in a cell adhesion molecule. J Am Chem Soc (2005) 1.27
Calcium binding to calmodulin: effects of ionic strength, Mg2+, pH and temperature. J Biochem (1984) 1.21
The prediction and characterization of metal binding sites in proteins. Protein Eng (1993) 1.12
Protein design based on folding models. Curr Opin Struct Biol (2001) 1.11
Rational design of a calcium-binding protein. J Am Chem Soc (2003) 1.09
Structural and thermodynamic analysis of the binding of solvent at internal sites in T4 lysozyme. Protein Sci (2001) 1.09
Metalloprotein design. Curr Opin Biotechnol (1996) 0.96
The tryptophan switch: changing ligand-binding specificity from type I to type II in SH3 domains. J Mol Biol (2004) 0.96
Identification of sequences encoding the detoxification metalloisomerase glyoxalase I in microbial genomes from several pathogenic organisms. J Mol Evol (2000) 0.89
Modelling of solvent positions around polar groups in proteins. Protein Eng (1991) 0.88
The effects of Mg2+ on the Ca2+-binding properties and Ca2+-induced tyrosine-fluorescence changes of calmodulin isolated from rabbit skeletal muscle. Eur J Biochem (1981) 0.82
Growth dynamics of isotactic polypropylene single crystals during isothermal crystallization from a miscible polymeric solvent. J Chem Phys (2004) 0.80
The role of metals in enzyme activity. Ann Clin Lab Sci (1977) 0.79
Predicting changes in the stability of proteins and protein complexes: a study of more than 1000 mutations. J Mol Biol (2002) 9.74
Structure-based redesign of the dimerization interface reduces the toxicity of zinc-finger nucleases. Nat Biotechnol (2007) 8.88
Prediction of sequence-dependent and mutational effects on the aggregation of peptides and proteins. Nat Biotechnol (2004) 7.02
The FoldX web server: an online force field. Nucleic Acids Res (2005) 6.30
Transcriptome complexity in a genome-reduced bacterium. Science (2009) 4.64
Correlation of mRNA and protein in complex biological samples. FEBS Lett (2009) 4.38
Proteome organization in a genome-reduced bacterium. Science (2009) 3.97
Impact of genome reduction on bacterial metabolism and its regulation. Science (2009) 3.45
Evolvability and hierarchy in rewired bacterial gene networks. Nature (2008) 3.43
Systematic discovery of new recognition peptides mediating protein interaction networks. PLoS Biol (2005) 3.28
PupaSuite: finding functional single nucleotide polymorphisms for large-scale genotyping purposes. Nucleic Acids Res (2006) 3.04
Gain of function of mutant p53 by coaggregation with multiple tumor suppressors. Nat Chem Biol (2011) 2.94
Structure-based assembly of protein complexes in yeast. Science (2004) 2.89
Exploring the sequence determinants of amyloid structure using position-specific scoring matrices. Nat Methods (2010) 2.74
From in vivo to in silico biology and back. Nature (2006) 2.74
The mechanism of γ-Secretase dysfunction in familial Alzheimer disease. EMBO J (2012) 2.72
Sequence determinants of amyloid fibril formation. Proc Natl Acad Sci U S A (2003) 2.71
SNPeffect: a database mapping molecular phenotypic effects of human non-synonymous coding SNPs. Nucleic Acids Res (2005) 2.69
Noise in transcription negative feedback loops: simulation and experimental analysis. Mol Syst Biol (2006) 2.69
De novo designed peptide-based amyloid fibrils. Proc Natl Acad Sci U S A (2002) 2.59
Control of Drosophila gastrulation by apical localization of adherens junctions and RhoGEF2. Science (2007) 2.51
How protein stability and new functions trade off. PLoS Comput Biol (2008) 2.41
Lipids revert inert Abeta amyloid fibrils to neurotoxic protofibrils that affect learning in mice. EMBO J (2007) 2.39
Molecular basis of xeroderma pigmentosum group C DNA recognition by engineered meganucleases. Nature (2008) 2.37
Quantification of mRNA and protein and integration with protein turnover in a bacterium. Mol Syst Biol (2011) 2.31
Neurotoxicity of Alzheimer's disease Aβ peptides is induced by small changes in the Aβ42 to Aβ40 ratio. EMBO J (2010) 2.26
The stability effects of protein mutations appear to be universally distributed. J Mol Biol (2007) 2.25
Protein aggregation and amyloidosis: confusion of the kinds? Curr Opin Struct Biol (2006) 2.10
A comparative study of the relationship between protein structure and beta-aggregation in globular and intrinsically disordered proteins. J Mol Biol (2004) 2.05
Engineering of large numbers of highly specific homing endonucleases that induce recombination on novel DNA targets. J Mol Biol (2005) 2.04
Analysis and description of HOLTIN service provision for AECG monitoring in complex indoor environments. Sensors (Basel) (2013) 2.02
Analysis of protein processing by N-terminal proteomics reveals novel species-specific substrate determinants of granzyme B orthologs. Mol Cell Proteomics (2008) 2.01
Protein folding: defining a "standard" set of experimental conditions and a preliminary kinetic data set of two-state proteins. Protein Sci (2005) 1.91
How evolutionary pressure against protein aggregation shaped chaperone specificity. J Mol Biol (2005) 1.91
Computer-aided design of a PDZ domain to recognize new target sequences. Nat Struct Biol (2002) 1.89
Short amino acid stretches can mediate amyloid formation in globular proteins: the Src homology 3 (SH3) case. Proc Natl Acad Sci U S A (2004) 1.83
Recognizing and defining true Ras binding domains I: biochemical analysis. J Mol Biol (2005) 1.76
Computer design of obligate heterodimer meganucleases allows efficient cutting of custom DNA sequences. Nucleic Acids Res (2008) 1.74
SNPeffect v2.0: a new step in investigating the molecular phenotypic effects of human non-synonymous SNPs. Bioinformatics (2006) 1.69
Analysis of the human E2 ubiquitin conjugating enzyme protein interaction network. Genome Res (2009) 1.68
Specificity and evolvability in eukaryotic protein interaction networks. PLoS Comput Biol (2006) 1.64
Strand-specific deep sequencing of the transcriptome. Genome Res (2010) 1.58
A graphical interface for the FoldX forcefield. Bioinformatics (2011) 1.50
A generative, probabilistic model of local protein structure. Proc Natl Acad Sci U S A (2008) 1.50
Engineering gene networks to emulate Drosophila embryonic pattern formation. PLoS Biol (2005) 1.48
Designed tumor necrosis factor-related apoptosis-inducing ligand variants initiating apoptosis exclusively via the DR5 receptor. Proc Natl Acad Sci U S A (2006) 1.45
Cross-talk between phosphorylation and lysine acetylation in a genome-reduced bacterium. Mol Syst Biol (2012) 1.44
SNPeffect 4.0: on-line prediction of molecular and structural effects of protein-coding variants. Nucleic Acids Res (2011) 1.44
Joint annotation of coding and non-coding single nucleotide polymorphisms and mutations in the SNPeffect and PupaSuite databases. Nucleic Acids Res (2007) 1.43
A detailed thermodynamic analysis of ras/effector complex interfaces. J Mol Biol (2004) 1.42
The amyloid stretch hypothesis: recruiting proteins toward the dark side. Proc Natl Acad Sci U S A (2005) 1.41
Energy estimation in protein design. Curr Opin Struct Biol (2002) 1.39
Bacterial transcriptomics: what is beyond the RNA horiz-ome? Nat Rev Microbiol (2011) 1.39
Redox proteomics of protein-bound methionine oxidation. Mol Cell Proteomics (2011) 1.37
PepX: a structural database of non-redundant protein-peptide complexes. Nucleic Acids Res (2009) 1.35
Towards cellular systems in 4D. Cell (2005) 1.33
Recognizing and defining true Ras binding domains II: in silico prediction based on homology modelling and energy calculations. J Mol Biol (2005) 1.33
Comprehensive methylome characterization of Mycoplasma genitalium and Mycoplasma pneumoniae at single-base resolution. PLoS Genet (2013) 1.32
Analyzing protein interaction networks using structural information. Annu Rev Biochem (2008) 1.32
Genetic variability in the mitochondrial serine protease HTRA2 contributes to risk for Parkinson disease. Hum Mutat (2008) 1.31
Design of a wearable device for ECG continuous monitoring using wireless technology. Conf Proc IEEE Eng Med Biol Soc (2004) 1.28
Calculation of mutational free energy changes in transition states for protein folding. Biophys J (2003) 1.27
Proteome-wide substrate analysis indicates substrate exclusion as a mechanism to generate caspase-7 versus caspase-3 specificity. Mol Cell Proteomics (2009) 1.27
Structural basis for increased toxicity of pathological aβ42:aβ40 ratios in Alzheimer disease. J Biol Chem (2011) 1.26
Space as the final frontier in stochastic simulations of biological systems. FEBS Lett (2005) 1.25
Predicted effects of missense mutations on native-state stability account for phenotypic outcome in phenylketonuria, a paradigm of misfolding diseases. Am J Hum Genet (2007) 1.24
A probabilistic model of RNA conformational space. PLoS Comput Biol (2009) 1.22
Engineering signal transduction pathways. Cell (2010) 1.21
Mutations other than null mutations producing a pathogenic loss of progranulin in frontotemporal dementia. Hum Mutat (2007) 1.20
Molecular basis of engineered meganuclease targeting of the endogenous human RAG1 locus. Nucleic Acids Res (2010) 1.19
Computational design of peptide ligands. Trends Biotechnol (2011) 1.19
Unspecific hydrophobic stabilization of folding transition states. Proc Natl Acad Sci U S A (2002) 1.16
Using protein design algorithms to understand the molecular basis of disease caused by protein-DNA interactions: the Pax6 example. Nucleic Acids Res (2010) 1.16
Using a structural and logics systems approach to infer bHLH-DNA binding specificity determinants. Nucleic Acids Res (2011) 1.15
Computer modelling in combination with in vitro studies reveals similar binding affinities of Drosophila Crumbs for the PDZ domains of Stardust and DmPar-6. Eur J Cell Biol (2006) 1.15
Comparative genomics and disorder prediction identify biologically relevant SH3 protein interactions. PLoS Comput Biol (2005) 1.15
Advancing cell biology through proteomics in space and time (PROSPECTS). Mol Cell Proteomics (2012) 1.15
The multiple-specificity landscape of modular peptide recognition domains. Mol Syst Biol (2011) 1.14
Cell type-specific importance of ras-c-raf complex association rate constants for MAPK signaling. Sci Signal (2009) 1.12
Personalized respiratory medicine: exploring the horizon, addressing the issues. Summary of a BRN-AJRCCM workshop held in Barcelona on June 12, 2014. Am J Respir Crit Care Med (2015) 1.12
Structures in systems biology. Curr Opin Struct Biol (2007) 1.11