Published in Drug Metab Dispos on July 13, 2005
Non-P450 aldehyde oxidizing enzymes: the aldehyde dehydrogenase superfamily. Expert Opin Drug Metab Toxicol (2008) 3.37
Olfaction in Parkinson's disease and related disorders. Neurobiol Dis (2011) 1.51
Role of CYP2A5 in the clearance of nicotine and cotinine: insights from studies on a Cyp2a5-null mouse model. J Pharmacol Exp Ther (2009) 1.29
Human UDP-glucuronosyltransferase UGT2A2: cDNA construction, expression, and functional characterization in comparison with UGT2A1 and UGT2A3. Pharmacogenet Genomics (2009) 0.97
Novel polymorphic human UDP-glucuronosyltransferase 2A3: cloning, functional characterization of enzyme variants, comparative tissue expression, and gene induction. Mol Pharmacol (2008) 0.91
Generation and characterization of a CYP2A13/2B6/2F1-transgenic mouse model. Drug Metab Dispos (2012) 0.90
A review of the mechanism of injury and treatment approaches for illness resulting from exposure to water-damaged buildings, mold, and mycotoxins. ScientificWorldJournal (2013) 0.88
A novel defensive mechanism against acetaminophen toxicity in the mouse lateral nasal gland: role of CYP2A5-mediated regulation of testosterone homeostasis and salivary androgen-binding protein expression. Mol Pharmacol (2011) 0.88
High abundance of testosterone and salivary androgen-binding protein in the lateral nasal gland of male mice. J Steroid Biochem Mol Biol (2009) 0.87
Intravenous formulation of N-hydroxy-N'-(4-n-butyl-2-methylphenyl)formamidine (HET0016) for inhibition of rat brain 20-hydroxyeicosatetraenoic acid formation. Drug Metab Dispos (2008) 0.85
Temporal integration in nasal lateralization of homologous alcohols. Toxicol Sci (2007) 0.79
Temporal integration in nasal lateralization of homologous propionates. Inhal Toxicol (2009) 0.78
Directed evolution reveals requisite sequence elements in the functional expression of P450 2F1 in Escherichia coli. Chem Res Toxicol (2012) 0.76
Effects of Bunch Rot (Botrytis cinerea) and Powdery Mildew (Erysiphe necator) Fungal Diseases on Wine Aroma. Front Chem (2017) 0.75
Gene expression and immunochemical localization of major cytochrome P450 drug-metabolizing enzymes in bovine nasal olfactory and respiratory mucosa. Inhal Toxicol (2015) 0.75
Generation and characterization of a novel CYP2A13--transgenic mouse model. Drug Metab Dispos (2014) 0.75
RPE65 is the isomerohydrolase in the retinoid visual cycle. Proc Natl Acad Sci U S A (2005) 4.61
Plasma soluble urokinase receptor levels are increased but do not distinguish primary from secondary focal segmental glomerulosclerosis. Kidney Int (2013) 3.97
MicroRNA-mediated control of oligodendrocyte differentiation. Neuron (2010) 3.24
HDAC1 and HDAC2 regulate oligodendrocyte differentiation by disrupting the beta-catenin-TCF interaction. Nat Neurosci (2009) 3.18
Reelin promoter hypermethylation in schizophrenia. Proc Natl Acad Sci U S A (2005) 3.12
High expression of PD-L1 in lung cancer may contribute to poor prognosis and tumor cells immune escape through suppressing tumor infiltrating dendritic cells maturation. Med Oncol (2010) 3.06
In situ proteolysis for protein crystallization and structure determination. Nat Methods (2007) 3.05
MiR-26a inhibits cell growth and tumorigenesis of nasopharyngeal carcinoma through repression of EZH2. Cancer Res (2011) 3.03
Reelin, lipoprotein receptors and synaptic plasticity. Nat Rev Neurosci (2006) 2.95
Reciprocal differentiation and tissue-specific pathogenesis of Th1, Th2, and Th17 cells in graft-versus-host disease. Blood (2009) 2.91
A local mechanism mediates NAD-dependent protection of axon degeneration. J Cell Biol (2005) 2.64
Organic cation transporters are determinants of oxaliplatin cytotoxicity. Cancer Res (2006) 2.37
Genome-wide association analysis identifies new lung cancer susceptibility loci in never-smoking women in Asia. Nat Genet (2012) 2.26
Toxicity of atmospheric aerosols on marine phytoplankton. Proc Natl Acad Sci U S A (2009) 2.25
Absence of donor Th17 leads to augmented Th1 differentiation and exacerbated acute graft-versus-host disease. Blood (2008) 2.24
Meta-analysis of B vitamin supplementation on plasma homocysteine, cardiovascular and all-cause mortality. Clin Nutr (2012) 2.17
A dynamic gene expression atlas covering the entire life cycle of rice. Plant J (2009) 2.15
Oxidative and electrophilic stress induces multidrug resistance-associated protein transporters via the nuclear factor-E2-related factor-2 transcriptional pathway. Hepatology (2007) 2.11
Activation of STAT6 by STING is critical for antiviral innate immunity. Cell (2011) 2.08
Insulin resistance in children with primary nephrotic syndrome and normal renal function. Pediatr Nephrol (2012) 2.03
Clinicopathological significance of microRNA-31, -143 and -145 expression in colorectal cancer. Dis Markers (2009) 2.02
Dietary and lifestyle changes associated with high prevalence of hyperuricemia and gout in the Shandong coastal cities of Eastern China. J Rheumatol (2008) 2.00
Spatial segregation of gamma-secretase and substrates in distinct membrane domains. J Biol Chem (2005) 1.98
Sample size calculations for evaluating a diagnostic test when the gold standard is missing at random. Stat Med (2010) 1.96
DNA methyltransferase inhibitors coordinately induce expression of the human reelin and glutamic acid decarboxylase 67 genes. Mol Pharmacol (2006) 1.95
Primate-specific microRNA-637 inhibits tumorigenesis in hepatocellular carcinoma by disrupting signal transducer and activator of transcription 3 signaling. Hepatology (2011) 1.93
Initial Evaluation of [(18)F]DCFPyL for Prostate-Specific Membrane Antigen (PSMA)-Targeted PET Imaging of Prostate Cancer. Mol Imaging Biol (2015) 1.90
The 5p15.33 locus is associated with risk of lung adenocarcinoma in never-smoking females in Asia. PLoS Genet (2010) 1.90
Liver-specific deletion of the NADPH-cytochrome P450 reductase gene: impact on plasma cholesterol homeostasis and the function and regulation of microsomal cytochrome P450 and heme oxygenase. J Biol Chem (2003) 1.88
Initial characterization of the glutamate-cysteine ligase modifier subunit Gclm(-/-) knockout mouse. Novel model system for a severely compromised oxidative stress response. J Biol Chem (2002) 1.87
A regulatory toolbox of MiniPromoters to drive selective expression in the brain. Proc Natl Acad Sci U S A (2010) 1.85
Aberrant regulation of planar cell polarity in polycystic kidney disease. J Am Soc Nephrol (2010) 1.81
Undisclosed antiretroviral drug use in a multinational clinical trial (HIV Prevention Trials Network 052). J Infect Dis (2013) 1.77
Prediction of cardioembolic, arterial, and lacunar causes of cryptogenic stroke by gene expression and infarct location. Stroke (2012) 1.77
Influence of common genetic variation on lung cancer risk: meta-analysis of 14 900 cases and 29 485 controls. Hum Mol Genet (2012) 1.77
Genetically altered mice to evaluate glutathione homeostasis in health and disease. Free Radic Biol Med (2004) 1.76
Obesity induces signs of premature cardiac aging in younger patients: the role of mitochondria. J Am Coll Cardiol (2011) 1.76
Development and function of myeloid-derived suppressor cells generated from mouse embryonic and hematopoietic stem cells. Stem Cells (2010) 1.75
ALDH1A isozymes are markers of human melanoma stem cells and potential therapeutic targets. Stem Cells (2012) 1.70
Müller cell-derived VEGF is a significant contributor to retinal neovascularization. J Pathol (2009) 1.69
Olig2 targets chromatin remodelers to enhancers to initiate oligodendrocyte differentiation. Cell (2013) 1.66
Are there differences between women's and men's antidepressant responses? Am J Psychiatry (2002) 1.64
Genetic composition of yield heterosis in an elite rice hybrid. Proc Natl Acad Sci U S A (2012) 1.63
Aldehyde dehydrogenase inhibitors: a comprehensive review of the pharmacology, mechanism of action, substrate specificity, and clinical application. Pharmacol Rev (2012) 1.62
Gene expression profiling of blood for the prediction of ischemic stroke. Stroke (2010) 1.61
Hydrogen sulfide treatment promotes glucose uptake by increasing insulin receptor sensitivity and ameliorates kidney lesions in type 2 diabetes. Antioxid Redox Signal (2013) 1.60
Basolateral targeting and microtubule-dependent transcytosis of the aquaporin-2 water channel. Am J Physiol Cell Physiol (2012) 1.60
A crucial role for Olig2 in white matter astrocyte development. Development (2007) 1.60
Fine mapping and identification of a candidate gene SSH1 in disseminated superficial actinic porokeratosis. Hum Mutat (2004) 1.59
Methylation profile of the promoter CpG islands of 31 genes that may contribute to colorectal carcinogenesis. World J Gastroenterol (2004) 1.58
Overexpression of phosphorylated mammalian target of rapamycin predicts lymph node metastasis and prognosis of chinese patients with gastric cancer. Clin Cancer Res (2009) 1.56
Atmospheric iron deposition: global distribution, variability, and human perturbations. Ann Rev Mar Sci (2009) 1.56
Klotho suppresses RIG-I-mediated senescence-associated inflammation. Nat Cell Biol (2011) 1.55
The hydrogen sulfide donor NaHS promotes angiogenesis in a rat model of hind limb ischemia. Antioxid Redox Signal (2010) 1.54
Decreased androgen receptor expression may contribute to spermatogenesis failure in rats exposed to low concentration of bisphenol A. Toxicol Lett (2013) 1.52
Signatures of cardioembolic and large-vessel ischemic stroke. Ann Neurol (2010) 1.50
Crystallographic studies of Xe and Kr binding within the large internal cavity of cytochrome ba3 from Thermus thermophilus: structural analysis and role of oxygen transport channels in the heme-Cu oxidases. Biochemistry (2008) 1.49
Cloning and characterization of a novel all-trans retinol short-chain dehydrogenase/reductase from the RPE. Invest Ophthalmol Vis Sci (2002) 1.46
Peregrine and saker falcon genome sequences provide insights into evolution of a predatory lifestyle. Nat Genet (2013) 1.45
Chronic asthma results in cognitive dysfunction in immature mice. Exp Neurol (2013) 1.44
Determination of the role of target tissue metabolism in lung carcinogenesis using conditional cytochrome P450 reductase-null mice. Cancer Res (2007) 1.44
Immortalization of pancreatic stellate cells as an in vitro model of pancreatic fibrosis: deactivation is induced by matrigel and N-acetylcysteine. Lab Invest (2005) 1.43
Structural determinants of odorant recognition by the human olfactory receptors OR1A1 and OR1A2. J Struct Biol (2007) 1.43
Repetitive element-mediated recombination as a mechanism for new gene origination in Drosophila. PLoS Genet (2007) 1.42
The cytochrome ba3 oxygen reductase from Thermus thermophilus uses a single input channel for proton delivery to the active site and for proton pumping. Proc Natl Acad Sci U S A (2009) 1.42
Intraretinal leakage and oxidation of LDL in diabetic retinopathy. Invest Ophthalmol Vis Sci (2008) 1.42
Porous boron nitride nanosheets for effective water cleaning. Nat Commun (2013) 1.42
Activating enhancer-binding protein-2β nucleolar localization predicts poor survival after stage I non-small cell lung cancer resection. Ann Thorac Surg (2011) 1.41
Structure- and function-based characterization of a new phosphoglycolate phosphatase from Thermoplasma acidophilum. J Biol Chem (2003) 1.41
Controlled surface modification of boron nitride nanotubes. Nanotechnology (2011) 1.41
Community-wide assessment of protein-interface modeling suggests improvements to design methodology. J Mol Biol (2011) 1.40
Interactions between human glutamate carboxypeptidase II and urea-based inhibitors: structural characterization. J Med Chem (2008) 1.39
Physiological mechanisms underlying OsNAC5-dependent tolerance of rice plants to abiotic stress. Planta (2011) 1.39
Rapamycin prevents early steps of the development of diabetic nephropathy in rats. Am J Nephrol (2007) 1.39
Concern microRNA-218 Inhibits Oxygen-induced Retinal Neovascularization via Reducing the Expression of Roundabout 1. Chin Med J (Engl) (2016) 1.38
Two point mutations of RPE65 from patients with retinal dystrophies decrease the stability of RPE65 protein and abolish its isomerohydrolase activity. J Biol Chem (2006) 1.38
Actinfilin is a Cul3 substrate adaptor, linking GluR6 kainate receptor subunits to the ubiquitin-proteasome pathway. J Biol Chem (2006) 1.38
Survey of access to gastroenterology in Canada: the SAGE wait times program. Can J Gastroenterol (2010) 1.37
RPE65 is an iron(II)-dependent isomerohydrolase in the retinoid visual cycle. J Biol Chem (2005) 1.36
A novel cryoprotection scheme for enhancing the diffraction of crystals of recombinant cytochrome ba3 oxidase from Thermus thermophilus. Acta Crystallogr D Biol Crystallogr (2005) 1.36
Involvement of microRNA-93, a new regulator of PTEN/Akt signaling pathway, in regulation of chemotherapeutic drug cisplatin chemosensitivity in ovarian cancer cells. FEBS Lett (2012) 1.35
Dynamic imaging of T cell-parasite interactions in the brains of mice chronically infected with Toxoplasma gondii. J Immunol (2009) 1.35
NuRD blocks reprogramming of mouse somatic cells into pluripotent stem cells. Stem Cells (2013) 1.35
Protection by tetrahydroxystilbene glucoside against cerebral ischemia: involvement of JNK, SIRT1, and NF-kappaB pathways and inhibition of intracellular ROS/RNS generation. Free Radic Biol Med (2009) 1.34
Overexpression of Grb2/HER2 signaling in Chinese gastric cancer: their relationship with clinicopathological parameters and prognostic significance. J Cancer Res Clin Oncol (2009) 1.34
Alzheimer disease Abeta production in the absence of S-palmitoylation-dependent targeting of BACE1 to lipid rafts. J Biol Chem (2008) 1.34
Associations between single nucleotide polymorphisms on chromosome 9p21 and risk of coronary heart disease in Chinese Han population. Arterioscler Thromb Vasc Biol (2008) 1.33
Genetic difference in susceptibility to the blood-retina barrier breakdown in diabetes and oxygen-induced retinopathy. Am J Pathol (2005) 1.33
Secondary breast cancer: a 5-year population-based study with review of the literature. APMIS (2009) 1.33
The large-scale distribution of somatic mutations in cancer genomes. Hum Mutat (2011) 1.32
The tiger genome and comparative analysis with lion and snow leopard genomes. Nat Commun (2013) 1.32
Reelin signaling antagonizes beta-amyloid at the synapse. Proc Natl Acad Sci U S A (2009) 1.32
The human reelin gene: transcription factors (+), repressors (-) and the methylation switch (+/-) in schizophrenia. Pharmacol Ther (2006) 1.32
Targeted expression of Cre recombinase to cone photoreceptors in transgenic mice. Mol Vis (2004) 1.31
CD4+CD25+Foxp3+ regulatory T cells depletion may attenuate the development of silica-induced lung fibrosis in mice. PLoS One (2010) 1.31
The pathogenic role of the canonical Wnt pathway in age-related macular degeneration. Invest Ophthalmol Vis Sci (2009) 1.31
Antidepressant effects of ginseng total saponins in the forced swimming test and chronic mild stress models of depression. Prog Neuropsychopharmacol Biol Psychiatry (2009) 1.30
Redox dysregulation affects the ventral but not dorsal hippocampus: impairment of parvalbumin neurons, gamma oscillations, and related behaviors. J Neurosci (2010) 1.30