PubRank

Daniel Durocher

Author PubWeight™ 144.01‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry. Nature 2002 37.66
2 Orchestration of the DNA-damage response by the RNF8 ubiquitin ligase. Science 2007 7.61
3 RNF168 binds and amplifies ubiquitin conjugates on damaged chromosomes to allow accumulation of repair proteins. Cell 2009 6.89
4 The RIDDLE syndrome protein mediates a ubiquitin-dependent signaling cascade at sites of DNA damage. Cell 2009 5.96
5 The CRAPome: a contaminant repository for affinity purification-mass spectrometry data. Nat Methods 2013 4.34
6 A phosphatase complex that dephosphorylates gammaH2AX regulates DNA damage checkpoint recovery. Nature 2005 4.33
7 A cell cycle-dependent regulatory circuit composed of 53BP1-RIF1 and BRCA1-CtIP controls DNA repair pathway choice. Mol Cell 2013 3.55
8 Regulation of DNA damage responses by ubiquitin and SUMO. Mol Cell 2013 3.43
9 Mitosis inhibits DNA double-strand break repair to guard against telomere fusions. Science 2014 3.31
10 A genome-wide screen identifies the evolutionarily conserved KEOPS complex as a telomere regulator. Cell 2006 2.71
11 53BP1 is a reader of the DNA-damage-induced H2A Lys 15 ubiquitin mark. Nature 2013 2.64
12 Non-canonical inhibition of DNA damage-dependent ubiquitination by OTUB1. Nature 2010 2.47
13 An allosteric inhibitor of the human Cdc34 ubiquitin-conjugating enzyme. Cell 2011 2.35
14 Xrcc4 physically links DNA end processing by polynucleotide kinase to DNA ligation by DNA ligase IV. EMBO J 2004 2.24
15 Saccharomyces cerevisiae Rad9 acts as a Mec1 adaptor to allow Rad53 activation. Curr Biol 2005 2.20
16 Regulatory ubiquitylation in response to DNA double-strand breaks. DNA Repair (Amst) 2009 2.17
17 PP4 is a gamma H2AX phosphatase required for recovery from the DNA damage checkpoint. EMBO Rep 2008 2.09
18 The molecular architecture of the mammalian DNA repair enzyme, polynucleotide kinase. Mol Cell 2005 2.09
19 Significant conservation of synthetic lethal genetic interaction networks between distantly related eukaryotes. Proc Natl Acad Sci U S A 2008 2.01
20 Structural and functional versatility of the FHA domain in DNA-damage signaling by the tumor suppressor kinase Chk2. Mol Cell 2002 1.99
21 MRE11 promotes AKT phosphorylation in direct response to DNA double-strand breaks. Cell Cycle 2011 1.97
22 The ubiquitous role of ubiquitin in the DNA damage response. DNA Repair (Amst) 2010 1.94
23 Elg1 forms an alternative PCNA-interacting RFC complex required to maintain genome stability. Curr Biol 2003 1.88
24 Systematic identification of fragile sites via genome-wide location analysis of gamma-H2AX. Nat Struct Mol Biol 2010 1.87
25 A viral E3 ligase targets RNF8 and RNF168 to control histone ubiquitination and DNA damage responses. EMBO J 2010 1.75
26 Tandem protein interaction modules organize the ubiquitin-dependent response to DNA double-strand breaks. Mol Cell 2012 1.62
27 OTUB1 co-opts Lys48-linked ubiquitin recognition to suppress E2 enzyme function. Mol Cell 2012 1.58
28 Atomic structure of the KEOPS complex: an ancient protein kinase-containing molecular machine. Mol Cell 2008 1.51
29 Problems with co-funding in Canada. Science 2005 1.48
30 APLF (C2orf13) facilitates nonhomologous end-joining and undergoes ATM-dependent hyperphosphorylation following ionizing radiation. DNA Repair (Amst) 2008 1.44
31 A strategy for modulation of enzymes in the ubiquitin system. Science 2013 1.43
32 Rnf8 deficiency impairs class switch recombination, spermatogenesis, and genomic integrity and predisposes for cancer. J Exp Med 2010 1.40
33 The F-box protein Dia2 overcomes replication impedance to promote genome stability in Saccharomyces cerevisiae. Genetics 2006 1.33
34 The MMS22L-TONSL complex mediates recovery from replication stress and homologous recombination. Mol Cell 2010 1.32
35 Push back to respond better: regulatory inhibition of the DNA double-strand break response. Nat Rev Mol Cell Biol 2013 1.29
36 The RNF8/RNF168 ubiquitin ligase cascade facilitates class switch recombination. Proc Natl Acad Sci U S A 2009 1.24
37 Genomic instability, defective spermatogenesis, immunodeficiency, and cancer in a mouse model of the RIDDLE syndrome. PLoS Genet 2011 1.23
38 De novo telomere formation is suppressed by the Mec1-dependent inhibition of Cdc13 accumulation at DNA breaks. Genes Dev 2010 1.22
39 Ccr4 contributes to tolerance of replication stress through control of CRT1 mRNA poly(A) tail length. J Cell Sci 2006 1.11
40 Rad6-Rad18 mediates a eukaryotic SOS response by ubiquitinating the 9-1-1 checkpoint clamp. Cell 2008 1.10
41 A screen for suppressors of gross chromosomal rearrangements identifies a conserved role for PLP in preventing DNA lesions. PLoS Genet 2007 1.06
42 CDC5 inhibits the hyperphosphorylation of the checkpoint kinase Rad53, leading to checkpoint adaptation. PLoS Biol 2010 1.05
43 Reconstitution and characterization of eukaryotic N6-threonylcarbamoylation of tRNA using a minimal enzyme system. Nucleic Acids Res 2013 1.00
44 Uroporphyrinogen decarboxylase is a radiosensitizing target for head and neck cancer. Sci Transl Med 2011 1.00
45 Interaction proteomics identify NEURL4 and the HECT E3 ligase HERC2 as novel modulators of centrosome architecture. Mol Cell Proteomics 2012 1.00
46 gammaH2AX as a checkpoint maintenance signal. Cell Cycle 2006 0.93
47 Chromatin and DNA repair: the benefits of relaxation. Nat Cell Biol 2006 0.90
48 Srs2 enables checkpoint recovery by promoting disassembly of DNA damage foci from chromatin. DNA Repair (Amst) 2011 0.90
49 RMI1 promotes DNA replication fork progression and recovery from replication fork stress. Mol Cell Biol 2012 0.89
50 The structural basis of modified nucleosome recognition by 53BP1. Nature 2016 0.86
51 A siRNA-based screen for genes involved in chromosome end protection. PLoS One 2011 0.86
52 DNA repair pathway choice--a PTIP of the hat to 53BP1. EMBO Rep 2013 0.85
53 DNA repair has a new FAN1 club. Mol Cell 2010 0.82
54 DNA repair: DNA polymerase zeta and Rev1 break in. Curr Biol 2006 0.79
55 Dun1 counts on rad53 to be turned on. Mol Cell 2008 0.78
56 Telomere protection: an act of God. Curr Biol 2006 0.77
57 Bacterial signal transduction: a FHAscinating glimpse at the origins of phospho-dependent signal transduction. Trends Microbiol 2003 0.77
58 Engineering a DNA damage response without DNA damage. Genome Biol 2008 0.75