Published in Mol Microbiol on September 01, 2005
Development of pyrF-based genetic system for targeted gene deletion in Clostridium thermocellum and creation of a pta mutant. Appl Environ Microbiol (2010) 2.12
Role of pore-forming toxins in bacterial infectious diseases. Microbiol Mol Biol Rev (2013) 1.91
Expanding the repertoire of gene tools for precise manipulation of the Clostridium difficile genome: allelic exchange using pyrE alleles. PLoS One (2013) 1.23
Novel system for efficient isolation of Clostridium double-crossover allelic exchange mutants enabling markerless chromosomal gene deletions and DNA integration. Appl Environ Microbiol (2012) 1.20
Clostridium septicum sepsis and colorectal cancer - a reminder. World J Surg Oncol (2009) 1.13
Engineering clostridium strain to accept unmethylated DNA. PLoS One (2010) 1.11
Programmed cellular necrosis mediated by the pore-forming alpha-toxin from Clostridium septicum. PLoS Pathog (2009) 1.09
Molecular and cellular basis of microvascular perfusion deficits induced by Clostridium perfringens and Clostridium septicum. PLoS Pathog (2008) 1.07
TcsL is an essential virulence factor in Clostridium sordellii ATCC 9714. Infect Immun (2011) 0.95
Clostridium septicum myonecrosis complicating diarrhea-associated hemolytic uremic syndrome. Pediatr Nephrol (2008) 0.92
Identification of functional domains of Clostridium septicum alpha toxin. Biochemistry (2006) 0.90
Pro-inflammatory feedback activation cycle evoked by attack of Vibrio cholerae cytolysin on human neutrophil granulocytes. Med Microbiol Immunol (2007) 0.89
Clostridium septicum Gas Gangrene in Colon Cancer: Importance of Early Diagnosis. Case Rep Infect Dis (2015) 0.89
Pore-forming activity of alpha-toxin is essential for clostridium septicum-mediated myonecrosis. Infect Immun (2009) 0.89
NetB, a pore-forming toxin from necrotic enteritis strains of Clostridium perfringens. Toxins (Basel) (2010) 0.87
The pore-forming α-toxin from clostridium septicum activates the MAPK pathway in a Ras-c-Raf-dependent and independent manner. Toxins (Basel) (2015) 0.81
Non-traumatic gas gangrene presenting as left buttock and thigh pain in a patient with metastatic non-small cell lung cancer. BMJ Case Rep (2010) 0.77
The CpAL quorum sensing system regulates production of hemolysins CPA and PFO to build Clostridium perfringens biofilms. Infect Immun (2015) 0.77
Clostridium septicum Aortitis of the Infrarenal Abdominal Aorta. J Clin Med Res (2015) 0.75
Developing controllable hypermutable Clostridium cells through manipulating its methyl-directed mismatch repair system. Protein Cell (2013) 0.75
Low prevalence of Clostridium septicum fecal carriage in an adult population. Anaerobe (2014) 0.75
Successful Treatment of Clostridium difficile Bacteremia with Aortic Mycotic Aneurysm in a Patient with Prior Endovascular Aortic Aneurysm Repair. Case Rep Infect Dis (2017) 0.75
Clostridium septicum: An Unusual Link to a Lower Gastrointestinal Bleed. Case Rep Gastroenterol (2016) 0.75
Presence of periaortic gas in Clostridium septicum-infected aortic aneurysm aids in early diagnosis: a case report and systematic review of the literature. J Med Case Rep (2017) 0.75
Toxin B is essential for virulence of Clostridium difficile. Nature (2009) 5.49
Regulation of intestinal inflammation by microbiota following allogeneic bone marrow transplantation. J Exp Med (2012) 3.17
Interleukin-22 protects intestinal stem cells from immune-mediated tissue damage and regulates sensitivity to graft versus host disease. Immunity (2012) 2.99
Interleukin-22 drives endogenous thymic regeneration in mice. Science (2012) 2.96
Skewed genomic variability in strains of the toxigenic bacterial pathogen, Clostridium perfringens. Genome Res (2006) 2.84
Developmental kinetics, turnover, and stimulatory capacity of thymic epithelial cells. Blood (2006) 2.72
Genome reduction in Leptospira borgpetersenii reflects limited transmission potential. Proc Natl Acad Sci U S A (2006) 2.71
Construction and analysis of chromosomal Clostridium difficile mutants. Mol Microbiol (2006) 2.65
The Lmo2 oncogene initiates leukemia in mice by inducing thymocyte self-renewal. Science (2010) 2.64
CCR7 signals are essential for cortex-medulla migration of developing thymocytes. J Exp Med (2004) 2.52
Gene dosage--limiting role of Aire in thymic expression, clonal deletion, and organ-specific autoimmunity. J Exp Med (2004) 2.43
Lymph node fibroblastic reticular cells directly present peripheral tissue antigen under steady-state and inflammatory conditions. J Exp Med (2010) 2.37
Genome sequence of the saprophyte Leptospira biflexa provides insights into the evolution of Leptospira and the pathogenesis of leptospirosis. PLoS One (2008) 2.35
Activation of thymic regeneration in mice and humans following androgen blockade. J Immunol (2005) 2.31
NetB, a new toxin that is associated with avian necrotic enteritis caused by Clostridium perfringens. PLoS Pathog (2008) 2.23
CCR7-dependent cortex-to-medulla migration of positively selected thymocytes is essential for establishing central tolerance. Immunity (2006) 2.12
The cell-surface marker MTS24 identifies a novel population of follicular keratinocytes with characteristics of progenitor cells. Development (2006) 2.04
Construction of an alpha toxin gene knockout mutant of Clostridium perfringens type A by use of a mobile group II intron. Appl Environ Microbiol (2005) 2.01
Redefining epithelial progenitor potential in the developing thymus. Eur J Immunol (2007) 1.81
Beta toxin is essential for the intestinal virulence of Clostridium perfringens type C disease isolate CN3685 in a rabbit ileal loop model. Mol Microbiol (2008) 1.78
Keratinocyte growth factor (KGF) is required for postnatal thymic regeneration. Blood (2005) 1.65
Alpha-toxin of Clostridium perfringens is not an essential virulence factor in necrotic enteritis in chickens. Infect Immun (2006) 1.62
Generalized resistance to thymic deletion in the NOD mouse; a polygenic trait characterized by defective induction of Bim. Immunity (2004) 1.57
Strategies to enhance T-cell reconstitution in immunocompromised patients. Nat Rev Immunol (2004) 1.56
Environmental response and autoregulation of Clostridium difficile TxeR, a sigma factor for toxin gene expression. J Bacteriol (2002) 1.53
Revised nomenclature for transposable genetic elements. Plasmid (2008) 1.50
Epsilon-toxin is required for most Clostridium perfringens type D vegetative culture supernatants to cause lethality in the mouse intravenous injection model. Infect Immun (2005) 1.49
Dissecting the contributions of Clostridium perfringens type C toxins to lethality in the mouse intravenous injection model. Infect Immun (2006) 1.49
Role for CCR7 ligands in the emigration of newly generated T lymphocytes from the neonatal thymus. Immunity (2002) 1.46
Unbiased analysis, enrichment and purification of thymic stromal cells. J Immunol Methods (2007) 1.45
Rethinking our understanding of the pathogenesis of necrotic enteritis in chickens. Trends Microbiol (2008) 1.39
Functional identification of conjugation and replication regions of the tetracycline resistance plasmid pCW3 from Clostridium perfringens. J Bacteriol (2006) 1.39
Severe infection with Clostridium difficile PCR ribotype 027 acquired in Melbourne, Australia. Med J Aust (2011) 1.38
Nrf2 regulates haematopoietic stem cell function. Nat Cell Biol (2013) 1.38
Effects of castration on thymocyte development in two different models of thymic involution. J Immunol (2005) 1.38
The role of toxin A and toxin B in Clostridium difficile-associated disease: Past and present perspectives. Gut Microbes (2010) 1.37
Self-produced exopolysaccharide is a signal that stimulates biofilm formation in Pseudomonas aeruginosa. Proc Natl Acad Sci U S A (2012) 1.36
Transcription of multiple var genes by individual, trophozoite-stage Plasmodium falciparum cells expressing a chondroitin sulphate A binding phenotype. Mol Microbiol (2002) 1.29
Binary toxin production in Clostridium difficile is regulated by CdtR, a LytTR family response regulator. J Bacteriol (2007) 1.29
The anti-sigma factor TcdC modulates hypervirulence in an epidemic BI/NAP1/027 clinical isolate of Clostridium difficile. PLoS Pathog (2011) 1.28
Revised nomenclature of Clostridium difficile toxins and associated genes. J Med Microbiol (2005) 1.28
Genome sequence and identification of candidate vaccine antigens from the animal pathogen Dichelobacter nodosus. Nat Biotechnol (2007) 1.25
Enhanced immune system regeneration in humans following allogeneic or autologous hemopoietic stem cell transplantation by temporary sex steroid blockade. Clin Cancer Res (2008) 1.20
The VirSR two-component signal transduction system regulates NetB toxin production in Clostridium perfringens. Infect Immun (2010) 1.20
TcpA, an FtsK/SpoIIIE homolog, is essential for transfer of the conjugative plasmid pCW3 in Clostridium perfringens. J Bacteriol (2007) 1.19
Tolerance strategies for stem-cell-based therapies. Nature (2008) 1.18
Epsilon-toxin plasmids of Clostridium perfringens type D are conjugative. J Bacteriol (2007) 1.16
Both epsilon-toxin and beta-toxin are important for the lethal properties of Clostridium perfringens type B isolates in the mouse intravenous injection model. Infect Immun (2007) 1.15
The role of toxin A and toxin B in the virulence of Clostridium difficile. Trends Microbiol (2011) 1.14
Sex steroid ablation enhances lymphoid recovery following autologous hematopoietic stem cell transplantation. Transplantation (2005) 1.13
The spatial organization of the VirR boxes is critical for VirR-mediated expression of the perfringolysin O gene, pfoA, from Clostridium perfringens. J Bacteriol (2004) 1.11
The subtilisin-like protease AprV2 is required for virulence and uses a novel disulphide-tethered exosite to bind substrates. PLoS Pathog (2010) 1.10
Development and application of new mouse models to study the pathogenesis of Clostridium perfringens type C Enterotoxemias. Infect Immun (2009) 1.10
Programmed cellular necrosis mediated by the pore-forming alpha-toxin from Clostridium septicum. PLoS Pathog (2009) 1.09
Novel molecular type of Clostridium difficile in neonatal pigs, Western Australia. Emerg Infect Dis (2013) 1.08
Thymic regeneration: teaching an old immune system new tricks. Trends Mol Med (2002) 1.08
The conjugation protein TcpC from Clostridium perfringens is structurally related to the type IV secretion system protein VirB8 from Gram-negative bacteria. Mol Microbiol (2011) 1.07
Molecular and cellular basis of microvascular perfusion deficits induced by Clostridium perfringens and Clostridium septicum. PLoS Pathog (2008) 1.07
The FxRxHrS motif: a conserved region essential for DNA binding of the VirR response regulator from Clostridium perfringens. J Mol Biol (2002) 1.07
Toxin plasmids of Clostridium perfringens. Microbiol Mol Biol Rev (2013) 1.07
Towards an understanding of the role of Clostridium perfringens toxins in human and animal disease. Future Microbiol (2014) 1.07
Influence of gastric acid on susceptibility to infection with ingested bacterial pathogens. Infect Immun (2007) 1.07
Association between avian necrotic enteritis and Clostridium perfringens strains expressing NetB toxin. Vet Res (2009) 1.05
The lymphotoxin pathway regulates Aire-independent expression of ectopic genes and chemokines in thymic stromal cells. J Immunol (2008) 1.05
Controlling the thymic microenvironment. Curr Opin Immunol (2005) 1.04
A unique thymic fibroblast population revealed by the monoclonal antibody MTS-15. J Immunol (2007) 1.03
Ablation and regeneration of tolerance-inducing medullary thymic epithelial cells after cyclosporine, cyclophosphamide, and dexamethasone treatment. J Immunol (2009) 1.02
The NanI and NanJ sialidases of Clostridium perfringens are not essential for virulence. Infect Immun (2009) 1.02
Type IV fimbrial biogenesis is required for protease secretion and natural transformation in Dichelobacter nodosus. J Bacteriol (2007) 1.02
Enhanced immune reconstitution by sex steroid ablation following allogeneic hemopoietic stem cell transplantation. J Immunol (2007) 1.01
Vascularized tissue engineering mouse chamber model supports thymopoiesis of ectopic thymus tissue grafts. Tissue Eng Part C Methods (2010) 1.00
The SKHR motif is required for biological function of the VirR response regulator from Clostridium perfringens. J Bacteriol (2003) 1.00
Spo0A differentially regulates toxin production in evolutionarily diverse strains of Clostridium difficile. PLoS One (2013) 0.99