Published in J Muscle Res Cell Motil on January 01, 2004
Ankyrin-B mutation causes type 4 long-QT cardiac arrhythmia and sudden cardiac death. Nature (2003) 5.94
Calmodulin kinase II inhibition protects against structural heart disease. Nat Med (2005) 5.87
Orphaned ryanodine receptors in the failing heart. Proc Natl Acad Sci U S A (2006) 3.99
T-tubule remodeling during transition from hypertrophy to heart failure. Circ Res (2010) 3.57
Calcium flickers steer cell migration. Nature (2008) 3.01
CaMKII determines mitochondrial stress responses in heart. Nature (2012) 2.63
Proarrhythmic defects in Timothy syndrome require calmodulin kinase II. Circulation (2008) 2.16
Fibroblast growth factor 14 is an intracellular modulator of voltage-gated sodium channels. J Physiol (2005) 2.05
Recovery of cardiac calcium release is controlled by sarcoplasmic reticulum refilling and ryanodine receptor sensitivity. Cardiovasc Res (2011) 1.98
Calmodulin kinase II is required for fight or flight sinoatrial node physiology. Proc Natl Acad Sci U S A (2009) 1.95
Carvedilol and its new analogs suppress arrhythmogenic store overload-induced Ca2+ release. Nat Med (2011) 1.88
Stabilization of cardiac ryanodine receptor prevents intracellular calcium leak and arrhythmias. Proc Natl Acad Sci U S A (2006) 1.87
Regulation of sarcoplasmic reticulum calcium release by luminal calcium in cardiac muscle. Front Biosci (2002) 1.84
Thermodynamically irreversible gating of ryanodine receptors in situ revealed by stereotyped duration of release in Ca(2+) sparks. Biophys J (2002) 1.80
Dysfunction in ankyrin-B-dependent ion channel and transporter targeting causes human sinus node disease. Proc Natl Acad Sci U S A (2008) 1.72
Regression analysis for constraining free parameters in electrophysiological models of cardiac cells. PLoS Comput Biol (2010) 1.62
Local recovery of Ca2+ release in rat ventricular myocytes. J Physiol (2005) 1.58
Dynamics of calcium sparks and calcium leak in the heart. Biophys J (2011) 1.57
Cyclosporine attenuates cardiomyocyte hypertrophy induced by RAF1 mutants in Noonan and LEOPARD syndromes. J Mol Cell Cardiol (2011) 1.55
The Ca 2+ leak paradox and rogue ryanodine receptors: SR Ca 2+ efflux theory and practice. Prog Biophys Mol Biol (2005) 1.54
CaV1.2 beta-subunit coordinates CaMKII-triggered cardiomyocyte death and afterdepolarizations. Proc Natl Acad Sci U S A (2010) 1.42
Mathematical model of the neonatal mouse ventricular action potential. Am J Physiol Heart Circ Physiol (2008) 1.37
Exploiting mathematical models to illuminate electrophysiological variability between individuals. J Physiol (2012) 1.35
Emerging mechanisms of T-tubule remodelling in heart failure. Cardiovasc Res (2013) 1.35
Local Ca(2+) signaling and EC coupling in heart: Ca(2+) sparks and the regulation of the [Ca(2+)](i) transient. J Mol Cell Cardiol (2002) 1.32
Quantification of repolarization reserve to understand interpatient variability in the response to proarrhythmic drugs: a computational analysis. Heart Rhythm (2011) 1.31
Oxidized Ca(2+)/calmodulin-dependent protein kinase II triggers atrial fibrillation. Circulation (2013) 1.29
Sildenafil prevents and reverses transverse-tubule remodeling and Ca(2+) handling dysfunction in right ventricle failure induced by pulmonary artery hypertension. Hypertension (2011) 1.27
Calcium biology of the transverse tubules in heart. Ann N Y Acad Sci (2005) 1.22
Junctophilin-2 is necessary for T-tubule maturation during mouse heart development. Cardiovasc Res (2013) 1.22
Imaging microdomain Ca2+ in muscle cells. Circ Res (2004) 1.17
I(f) and SR Ca(2+) release both contribute to pacemaker activity in canine sinoatrial node cells. J Mol Cell Cardiol (2010) 1.14
Predicting local SR Ca(2+) dynamics during Ca(2+) wave propagation in ventricular myocytes. Biophys J (2010) 1.10
Polymorphism of Ca2+ sparks evoked from in-focus Ca2+ release units in cardiac myocytes. Biophys J (2004) 1.09
A comparison of murine smooth muscle cells generated from embryonic versus induced pluripotent stem cells. Stem Cells Dev (2009) 1.09
Hypertrophic phenotype in cardiac cell assemblies solely by structural cues and ensuing self-organization. FASEB J (2010) 1.08
β-Adrenergic receptor antagonists ameliorate myocyte T-tubule remodeling following myocardial infarction. FASEB J (2012) 1.06
PI3Ks maintain the structural integrity of T-tubules in cardiac myocytes. PLoS One (2011) 1.03
Microtubule-mediated defects in junctophilin-2 trafficking contribute to myocyte transverse-tubule remodeling and Ca2+ handling dysfunction in heart failure. Circulation (2014) 1.02
Inquiry learning. Integrating content detail and critical reasoning by peer review. Science (2008) 1.02
Restitution of Ca(2+) release and vulnerability to arrhythmias. J Cardiovasc Electrophysiol (2006) 1.02
Allosteric activation of Na+-Ca2+ exchange by L-type Ca2+ current augments the trigger flux for SR Ca2+ release in ventricular myocytes. Biophys J (2008) 1.01
Local control of Ca2+-induced Ca2+ release in mouse sinoatrial node cells. J Mol Cell Cardiol (2009) 1.00
Imaging calcium sparks in cardiac myocytes. Methods Mol Biol (2011) 1.00
Unique properties of the ATP-sensitive K⁺ channel in the mouse ventricular cardiac conduction system. Circ Arrhythm Electrophysiol (2011) 1.00
Critical roles of junctophilin-2 in T-tubule and excitation-contraction coupling maturation during postnatal development. Cardiovasc Res (2013) 0.99
FKBP12 is a critical regulator of the heart rhythm and the cardiac voltage-gated sodium current in mice. Circ Res (2011) 0.99
Parameter sensitivity analysis of stochastic models provides insights into cardiac calcium sparks. Biophys J (2013) 0.96
Moment closure for local control models of calcium-induced calcium release in cardiac myocytes. Biophys J (2008) 0.96
Catecholamine-independent heart rate increases require Ca2+/calmodulin-dependent protein kinase II. Circ Arrhythm Electrophysiol (2011) 0.95
A probability density approach to modeling local control of calcium-induced calcium release in cardiac myocytes. Biophys J (2007) 0.95
Phospholamban knockout breaks arrhythmogenic Ca²⁺ waves and suppresses catecholaminergic polymorphic ventricular tachycardia in mice. Circ Res (2013) 0.92
Calsequestrin accumulation in rough endoplasmic reticulum promotes perinuclear Ca2+ release. J Biol Chem (2012) 0.91
Teaching resources. Using web-based discussion forums as a model of the peer-review process and a tool for assessment. Sci Signal (2008) 0.91
Spontaneous Ca2+ sparks and Ca2+ homeostasis in a minimal model of permeabilized ventricular myocytes. Am J Physiol Heart Circ Physiol (2010) 0.89
Models of cardiac excitation-contraction coupling in ventricular myocytes. Math Biosci (2010) 0.89
Twenty years of calcium imaging: cell physiology to dye for. Mol Interv (2005) 0.88
Na+ channel function, regulation, structure, trafficking and sequestration. J Physiol (2015) 0.88
In situ confocal imaging in intact heart reveals stress-induced Ca(2+) release variability in a murine catecholaminergic polymorphic ventricular tachycardia model of type 2 ryanodine receptor(R4496C+/-) mutation. Circ Arrhythm Electrophysiol (2012) 0.88
The challenge of molecular medicine: complexity versus Occam's razor. J Clin Invest (2003) 0.88
Alterations in T-tubule and dyad structure in heart disease: challenges and opportunities for computational analyses. Cardiovasc Res (2013) 0.87
Does the Goldilocks Principle apply to calcium release restitution in heart cells? J Mol Cell Cardiol (2011) 0.86
Expression of a sorcin missense mutation in the heart modulates excitation-contraction coupling. FASEB J (2006) 0.86
Retracted beta-Adrenergic receptor activation induces internalization of cardiac Cav1.2 channel complexes through a beta-arrestin 1-mediated pathway. J Biol Chem (2008) 0.86
Sarcolemmal ATP-sensitive potassium channels modulate skeletal muscle function under low-intensity workloads. J Gen Physiol (2013) 0.86
Decoding myocardial Ca²⁺ signals across multiple spatial scales: a role for sensitivity analysis. J Mol Cell Cardiol (2012) 0.84
Distribution of ryanodine receptors in rat ventricular myocytes. J Muscle Res Cell Motil (2009) 0.84
Complex and rate-dependent beat-to-beat variations in Ca2+ transients of canine Purkinje cells. J Mol Cell Cardiol (2011) 0.83
Calmodulin regulation of excitation-contraction coupling in cardiac myocytes. Circ Res (2003) 0.83
A network medicine approach to build a comprehensive atlas for the prognosis of human cancer. Brief Bioinform (2016) 0.82
Maximal acceleration of Ca2+ release refractoriness by β-adrenergic stimulation requires dual activation of kinases PKA and CaMKII in mouse ventricular myocytes. J Physiol (2014) 0.82
Serine protease EspP from enterohemorrhagic Escherichia coli is sufficient to induce shiga toxin macropinocytosis in intestinal epithelium. PLoS One (2013) 0.82
Photochemical gating of intracellular Ca2+ release channels. J Am Chem Soc (2007) 0.82
Mutations in a helix-1 motif of the ATP synthase c-subunit of Bacillus pseudofirmus OF4 cause functional deficits and changes in the c-ring stability and mobility on sodium dodecyl sulfate-polyacrylamide gel electrophoresis. Biochemistry (2011) 0.81
Na+/Ca2+ exchanger-1 protects against systolic failure in the Akitains2 model of diabetic cardiomyopathy via a CXCR4/NF-κB pathway. Am J Physiol Heart Circ Physiol (2012) 0.80
Yoga for the sinoatrial node: sarcoplasmic reticulum calcium release confers flexibility. J Mol Cell Cardiol (2013) 0.80
Effects of ginkgo biloba extract on cation currents in rat ventricular myocytes. Life Sci (2005) 0.79
MicroRNA: a toolkit fine-tuning the dyadic "fuzzy space"? Circ Res (2012) 0.78
Keeping the beat: life without SERCA--is it possible? J Mol Cell Cardiol (2009) 0.78
Stochastic simulation of cardiac ventricular myocyte calcium dynamics and waves. Conf Proc IEEE Eng Med Biol Soc (2011) 0.77
New insights into the structure and function of couplons. J Physiol (2008) 0.76
Physiologic gating properties of unitary cardiac L-type Ca2+ channels. Biochem Biophys Res Commun (2010) 0.76
Deciphering the pecking order of HCN4 expression in the developing heart: lessons from chicken. Heart Rhythm (2011) 0.75
Computer simulation of voltage sensitive calcium ion channels in a dendritic spine. J Theor Biol (2013) 0.75
Corrigendum: The mitochondrial uniporter controls fight or flight heart rate increases. Nat Commun (2015) 0.75