MicroRNA: a toolkit fine-tuning the dyadic "fuzzy space"?

PubWeight™: 0.78‹?›

🔗 View Article (PMC 3505765)

Published in Circ Res on September 14, 2012

Authors

Long-Sheng Song, Ang Guo, Richard Z Lin

Articles cited by this

A calcineurin-dependent transcriptional pathway for cardiac hypertrophy. Cell (1998) 13.56

Theory of excitation-contraction coupling in cardiac muscle. Biophys J (1992) 8.57

Pervasive roles of microRNAs in cardiovascular biology. Nature (2011) 6.08

Shape, size, and distribution of Ca(2+) release units and couplons in skeletal and cardiac muscles. Biophys J (1999) 5.37

Defective excitation-contraction coupling in experimental cardiac hypertrophy and heart failure. Science (1997) 4.81

Junctophilins: a novel family of junctional membrane complex proteins. Mol Cell (2000) 4.45

Orphaned ryanodine receptors in the failing heart. Proc Natl Acad Sci U S A (2006) 3.99

Ca2+ signalling between single L-type Ca2+ channels and ryanodine receptors in heart cells. Nature (2001) 3.79

T-tubule remodeling during transition from hypertrophy to heart failure. Circ Res (2010) 3.57

Reduction in density of transverse tubules and L-type Ca(2+) channels in canine tachycardia-induced heart failure. Cardiovasc Res (2001) 3.39

Local control models of cardiac excitation-contraction coupling. A possible role for allosteric interactions between ryanodine receptors. J Gen Physiol (1999) 3.14

Sodium-calcium exchange in excitable cells: fuzzy space. Science (1990) 2.95

Cellular basis of abnormal calcium transients of failing human ventricular myocytes. Circ Res (2003) 2.86

Direct measurement of SR release flux by tracking 'Ca2+ spikes' in rat cardiac myocytes. J Physiol (1998) 2.78

Loss of T-tubules and other changes to surface topography in ventricular myocytes from failing human and rat heart. Proc Natl Acad Sci U S A (2009) 2.61

T-tubule disorganization and reduced synchrony of Ca2+ release in murine cardiomyocytes following myocardial infarction. J Physiol (2006) 2.50

Dyssynchronous Ca(2+) sparks in myocytes from infarcted hearts. Circ Res (2000) 2.39

miR-23a functions downstream of NFATc3 to regulate cardiac hypertrophy. Proc Natl Acad Sci U S A (2009) 2.33

Abnormalities of calcium cycling in the hypertrophied and failing heart. J Mol Cell Cardiol (2000) 2.25

Disrupted junctional membrane complexes and hyperactive ryanodine receptors after acute junctophilin knockdown in mice. Circulation (2011) 2.21

Remodeling of T-tubules and reduced synchrony of Ca2+ release in myocytes from chronically ischemic myocardium. Circ Res (2007) 2.00

Depletion of T-tubules and specific subcellular changes in sarcolemmal proteins in tachycardia-induced heart failure. Cardiovasc Res (2003) 1.91

Intermolecular failure of L-type Ca2+ channel and ryanodine receptor signaling in hypertrophy. PLoS Biol (2007) 1.70

Junctophilin type 2 is associated with caveolin-3 and is down-regulated in the hypertrophic and dilated cardiomyopathies. Biochem Biophys Res Commun (2004) 1.69

Ultrastructural remodelling of Ca(2+) signalling apparatus in failing heart cells. Cardiovasc Res (2012) 1.65

Changes in the organization of excitation-contraction coupling structures in failing human heart. PLoS One (2011) 1.59

Characterization of an extensive transverse tubular network in sheep atrial myocytes and its depletion in heart failure. Circ Heart Fail (2009) 1.52

Subcellular structures and function of myocytes impaired during heart failure are restored by cardiac resynchronization therapy. Circ Res (2012) 1.44

Sildenafil prevents and reverses transverse-tubule remodeling and Ca(2+) handling dysfunction in right ventricle failure induced by pulmonary artery hypertension. Hypertension (2011) 1.27

Plasticity of surface structures and β(2)-adrenergic receptor localization in failing ventricular cardiomyocytes during recovery from heart failure. Circ Heart Fail (2012) 1.23

Mir-24 regulates junctophilin-2 expression in cardiomyocytes. Circ Res (2012) 1.07

β-Adrenergic receptor antagonists ameliorate myocyte T-tubule remodeling following myocardial infarction. FASEB J (2012) 1.06

PI3Ks maintain the structural integrity of T-tubules in cardiac myocytes. PLoS One (2011) 1.03

Articles by these authors

Ankyrin-B mutation causes type 4 long-QT cardiac arrhythmia and sudden cardiac death. Nature (2003) 5.94

Calmodulin kinase II inhibition protects against structural heart disease. Nat Med (2005) 5.87

T-tubule remodeling during transition from hypertrophy to heart failure. Circ Res (2010) 3.57

Calcium flickers steer cell migration. Nature (2008) 3.01

CaMKII determines mitochondrial stress responses in heart. Nature (2012) 2.63

Proarrhythmic defects in Timothy syndrome require calmodulin kinase II. Circulation (2008) 2.16

Class III PI3K Vps34 plays an essential role in autophagy and in heart and liver function. Proc Natl Acad Sci U S A (2012) 2.14

Suppression of phosphoinositide 3-kinase signaling and alteration of multiple ion currents in drug-induced long QT syndrome. Sci Transl Med (2012) 1.99

Calmodulin kinase II is required for fight or flight sinoatrial node physiology. Proc Natl Acad Sci U S A (2009) 1.95

The class IA phosphatidylinositol 3-kinase p110-beta subunit is a positive regulator of autophagy. J Cell Biol (2010) 1.91

Carvedilol and its new analogs suppress arrhythmogenic store overload-induced Ca2+ release. Nat Med (2011) 1.88

Stabilization of cardiac ryanodine receptor prevents intracellular calcium leak and arrhythmias. Proc Natl Acad Sci U S A (2006) 1.87

Thermodynamically irreversible gating of ryanodine receptors in situ revealed by stereotyped duration of release in Ca(2+) sparks. Biophys J (2002) 1.80

Dysfunction in ankyrin-B-dependent ion channel and transporter targeting causes human sinus node disease. Proc Natl Acad Sci U S A (2008) 1.72

PI 3-kinase regulation of dopamine uptake. J Neurochem (2002) 1.64

Local recovery of Ca2+ release in rat ventricular myocytes. J Physiol (2005) 1.58

The Ca 2+ leak paradox and rogue ryanodine receptors: SR Ca 2+ efflux theory and practice. Prog Biophys Mol Biol (2005) 1.54

Moderate pulmonary arterial hypertension in male mice lacking the vasoactive intestinal peptide gene. Circulation (2007) 1.53

Rapamycin and mTOR kinase inhibitors. J Chem Biol (2008) 1.51

CaV1.2 beta-subunit coordinates CaMKII-triggered cardiomyocyte death and afterdepolarizations. Proc Natl Acad Sci U S A (2010) 1.42

Emerging mechanisms of T-tubule remodelling in heart failure. Cardiovasc Res (2013) 1.35

Oxidized Ca(2+)/calmodulin-dependent protein kinase II triggers atrial fibrillation. Circulation (2013) 1.29

Sildenafil prevents and reverses transverse-tubule remodeling and Ca(2+) handling dysfunction in right ventricle failure induced by pulmonary artery hypertension. Hypertension (2011) 1.27

Loss of cardiac phosphoinositide 3-kinase p110 alpha results in contractile dysfunction. Circulation (2009) 1.22

Junctophilin-2 is necessary for T-tubule maturation during mouse heart development. Cardiovasc Res (2013) 1.22

Imaging microdomain Ca2+ in muscle cells. Circ Res (2004) 1.17

I(f) and SR Ca(2+) release both contribute to pacemaker activity in canine sinoatrial node cells. J Mol Cell Cardiol (2010) 1.14

Activated G alpha q inhibits p110 alpha phosphatidylinositol 3-kinase and Akt. J Biol Chem (2003) 1.12

Class IA PI3K p110β subunit promotes autophagy through Rab5 small GTPase in response to growth factor limitation. Mol Cell (2013) 1.11

A comparison of murine smooth muscle cells generated from embryonic versus induced pluripotent stem cells. Stem Cells Dev (2009) 1.09

Polymorphism of Ca2+ sparks evoked from in-focus Ca2+ release units in cardiac myocytes. Biophys J (2004) 1.09

Inhibition of mammalian target of rapamycin signaling by 2-(morpholin-1-yl)pyrimido[2,1-alpha]isoquinolin-4-one. J Biol Chem (2007) 1.08

Angiogenesis is induced by airway smooth muscle strain. Am J Physiol Lung Cell Mol Physiol (2007) 1.08

A transgenic mouse model of heart failure using inducible Galpha q. J Biol Chem (2005) 1.07

β-Adrenergic receptor antagonists ameliorate myocyte T-tubule remodeling following myocardial infarction. FASEB J (2012) 1.06

Decreased L-type Ca2+ current in cardiac myocytes of type 1 diabetic Akita mice due to reduced phosphatidylinositol 3-kinase signaling. Diabetes (2007) 1.05

PI3Ks maintain the structural integrity of T-tubules in cardiac myocytes. PLoS One (2011) 1.03

Galphaq binds to p110alpha/p85alpha phosphoinositide 3-kinase and displaces Ras. Biochem J (2006) 1.03

Microtubule-mediated defects in junctophilin-2 trafficking contribute to myocyte transverse-tubule remodeling and Ca2+ handling dysfunction in heart failure. Circulation (2014) 1.02

Restitution of Ca(2+) release and vulnerability to arrhythmias. J Cardiovasc Electrophysiol (2006) 1.02

Local control of Ca2+-induced Ca2+ release in mouse sinoatrial node cells. J Mol Cell Cardiol (2009) 1.00

Imaging calcium sparks in cardiac myocytes. Methods Mol Biol (2011) 1.00

Critical roles of junctophilin-2 in T-tubule and excitation-contraction coupling maturation during postnatal development. Cardiovasc Res (2013) 0.99

FKBP12 is a critical regulator of the heart rhythm and the cardiac voltage-gated sodium current in mice. Circ Res (2011) 0.99

Galpha q inhibits cardiac L-type Ca2+ channels through phosphatidylinositol 3-kinase. J Biol Chem (2005) 0.99

PI3K signaling supports amphetamine-induced dopamine efflux. Biochem Biophys Res Commun (2008) 0.97

Selective decreases in amphetamine self-administration and regulation of dopamine transporter function in diabetic rats. Neuroendocrinology (2003) 0.96

Catecholamine-independent heart rate increases require Ca2+/calmodulin-dependent protein kinase II. Circ Arrhythm Electrophysiol (2011) 0.95

Phospholamban knockout breaks arrhythmogenic Ca²⁺ waves and suppresses catecholaminergic polymorphic ventricular tachycardia in mice. Circ Res (2013) 0.92

Increased persistent sodium current due to decreased PI3K signaling contributes to QT prolongation in the diabetic heart. Diabetes (2013) 0.91

Calsequestrin accumulation in rough endoplasmic reticulum promotes perinuclear Ca2+ release. J Biol Chem (2012) 0.91

Phospholipase C-independent activation of glycogen synthase kinase-3beta and C-terminal Src kinase by Galphaq. J Biol Chem (2003) 0.91

Pathological impact of SMN2 mis-splicing in adult SMA mice. EMBO Mol Med (2013) 0.88

Twenty years of calcium imaging: cell physiology to dye for. Mol Interv (2005) 0.88

In situ confocal imaging in intact heart reveals stress-induced Ca(2+) release variability in a murine catecholaminergic polymorphic ventricular tachycardia model of type 2 ryanodine receptor(R4496C+/-) mutation. Circ Arrhythm Electrophysiol (2012) 0.88

The challenge of molecular medicine: complexity versus Occam's razor. J Clin Invest (2003) 0.88

Ca(2+)- and phospholipase D-dependent and -independent pathways activate mTOR signaling. FEBS Lett (2003) 0.87

Mammalian PIK3C3/VPS34: the key to autophagic processing in liver and heart. Autophagy (2012) 0.87

Sarcolemmal ATP-sensitive potassium channels modulate skeletal muscle function under low-intensity workloads. J Gen Physiol (2013) 0.86

VIP and endothelin receptor antagonist: an effective combination against experimental pulmonary arterial hypertension. Respir Res (2011) 0.85

Restoration of defective L-type Ca2+ current in cardiac myocytes of type 2 diabetic db/db mice by Akt and PKC-ι. J Cardiovasc Pharmacol (2011) 0.84

Calmodulin regulation of excitation-contraction coupling in cardiac myocytes. Circ Res (2003) 0.83

Stimulation of the alpha1A adrenergic receptor inhibits PDGF-induced PDGF beta receptor Tyr751 phosphorylation and PI 3-kinase activation. FEBS Lett (2003) 0.83

Ablation of PI3K p110-α prevents high-fat diet-induced liver steatosis. Diabetes (2011) 0.83

AKT activation promotes PTEN hamartoma tumor syndrome-associated cataract development. J Clin Invest (2013) 0.82

Reversible heart failure in G alpha(q) transgenic mice. J Biol Chem (2006) 0.81

Effects of ginkgo biloba extract on cation currents in rat ventricular myocytes. Life Sci (2005) 0.79

Activation of Gαq in Cardiomyocytes Increases Vps34 Activity and Stimulates Autophagy. J Cardiovasc Pharmacol (2017) 0.77

Preservation of the pHi during ischemia via PKC by intermittent hypoxia. Biochem Biophys Res Commun (2007) 0.76

TRIM21 Ubiquitylates SQSTM1/p62 and Suppresses Protein Sequestration to Regulate Redox Homeostasis. Mol Cell (2016) 0.76

The beta identity of class I PtdIns3K: A positive role of p110β in autophagy revealed. Autophagy (2011) 0.75

Deciphering the pecking order of HCN4 expression in the developing heart: lessons from chicken. Heart Rhythm (2011) 0.75

Ca2+ sparks in heart muscle. J Muscle Res Cell Motil (2004) 0.75

Chemically Cross-Linked MOF Membrane Generated from Imidazolium-Based Ionic Liquid Decorated UiO-66 Type NMOF and its Application toward CO2 Separation and Conversion. ACS Appl Mater Interfaces (2017) 0.75

Corrigendum: The mitochondrial uniporter controls fight or flight heart rate increases. Nat Commun (2015) 0.75