Published in Am J Physiol on June 01, 1992
Occludin: a novel integral membrane protein localizing at tight junctions. J Cell Biol (1993) 10.65
Claudin-1 and -2: novel integral membrane proteins localizing at tight junctions with no sequence similarity to occludin. J Cell Biol (1998) 7.78
Size-selective loosening of the blood-brain barrier in claudin-5-deficient mice. J Cell Biol (2003) 5.74
Claudin multigene family encoding four-transmembrane domain protein components of tight junction strands. Proc Natl Acad Sci U S A (1999) 5.54
Claudin-based tight junctions are crucial for the mammalian epidermal barrier: a lesson from claudin-1-deficient mice. J Cell Biol (2002) 5.51
Direct binding of three tight junction-associated MAGUKs, ZO-1, ZO-2, and ZO-3, with the COOH termini of claudins. J Cell Biol (1999) 5.06
Direct association of occludin with ZO-1 and its possible involvement in the localization of occludin at tight junctions. J Cell Biol (1994) 5.01
Complex phenotype of mice lacking occludin, a component of tight junction strands. Mol Biol Cell (2000) 4.69
A single gene product, claudin-1 or -2, reconstitutes tight junction strands and recruits occludin in fibroblasts. J Cell Biol (1998) 4.64
Prominin, a novel microvilli-specific polytopic membrane protein of the apical surface of epithelial cells, is targeted to plasmalemmal protrusions of non-epithelial cells. Proc Natl Acad Sci U S A (1997) 4.04
Involvement of ZO-1 in cadherin-based cell adhesion through its direct binding to alpha catenin and actin filaments. J Cell Biol (1997) 4.00
Endothelial claudin: claudin-5/TMVCF constitutes tight junction strands in endothelial cells. J Cell Biol (1999) 3.78
Conversion of zonulae occludentes from tight to leaky strand type by introducing claudin-2 into Madin-Darby canine kidney I cells. J Cell Biol (2001) 3.66
Occludin-deficient embryonic stem cells can differentiate into polarized epithelial cells bearing tight junctions. J Cell Biol (1998) 3.62
Manner of interaction of heterogeneous claudin species within and between tight junction strands. J Cell Biol (1999) 3.57
The tight junction protein ZO-1 is homologous to the Drosophila discs-large tumor suppressor protein of septate junctions. Proc Natl Acad Sci U S A (1993) 3.48
Enteric bacterial toxins: mechanisms of action and linkage to intestinal secretion. Microbiol Rev (1996) 3.46
Molecular characterization and tissue distribution of ZO-2, a tight junction protein homologous to ZO-1 and the Drosophila discs-large tumor suppressor protein. J Cell Biol (1994) 3.45
Possible involvement of phosphorylation of occludin in tight junction formation. J Cell Biol (1997) 3.35
Clostridium perfringens enterotoxin fragment removes specific claudins from tight junction strands: Evidence for direct involvement of claudins in tight junction barrier. J Cell Biol (1999) 3.02
Interspecies diversity of the occludin sequence: cDNA cloning of human, mouse, dog, and rat-kangaroo homologues. J Cell Biol (1996) 2.94
COOH terminus of occludin is required for tight junction barrier function in early Xenopus embryos. J Cell Biol (1997) 2.71
Intestinal barrier function: molecular regulation and disease pathogenesis. J Allergy Clin Immunol (2009) 2.63
Pores in the wall: claudins constitute tight junction strands containing aqueous pores. J Cell Biol (2000) 2.62
Assembly of the tight junction: the role of diacylglycerol. J Cell Biol (1993) 2.61
Medicinal chemical properties of successful central nervous system drugs. NeuroRx (2005) 2.55
Der p 1 facilitates transepithelial allergen delivery by disruption of tight junctions. J Clin Invest (1999) 2.53
Claudin-11/OSP-based tight junctions of myelin sheaths in brain and Sertoli cells in testis. J Cell Biol (1999) 2.40
Catenins and zonula occludens-1 form a complex during early stages in the assembly of tight junctions. J Cell Biol (1996) 2.37
Alveolar epithelial ion and fluid transport: recent progress. Am J Respir Cell Mol Biol (2006) 2.20
Zonula occludens toxin modulates tight junctions through protein kinase C-dependent actin reorganization, in vitro. J Clin Invest (1995) 2.14
Regulation of endothelial cell motility by complexes of tetraspan molecules CD81/TAPA-1 and CD151/PETA-3 with alpha3 beta1 integrin localized at endothelial lateral junctions. J Cell Biol (1998) 2.06
WIF-B cells: an in vitro model for studies of hepatocyte polarity. J Cell Biol (1993) 2.04
Clostridium difficile toxins disrupt epithelial barrier function by altering membrane microdomain localization of tight junction proteins. Infect Immun (2001) 1.85
The molecular organization of tight junctions. J Cell Biol (1993) 1.81
A small rab GTPase is distributed in cytoplasmic vesicles in non polarized cells but colocalizes with the tight junction marker ZO-1 in polarized epithelial cells. J Cell Biol (1994) 1.80
Restoration of tight junction structure and barrier function by down-regulation of the mitogen-activated protein kinase pathway in ras-transformed Madin-Darby canine kidney cells. Mol Biol Cell (2000) 1.76
Sinuous is a Drosophila claudin required for septate junction organization and epithelial tube size control. J Cell Biol (2004) 1.74
Dynamic behavior of paired claudin strands within apposing plasma membranes. Proc Natl Acad Sci U S A (2003) 1.66
Transcellular water transport in lung alveolar epithelium through mercury-sensitive water channels. Proc Natl Acad Sci U S A (1994) 1.59
Biological role of connexin intercellular channels and hemichannels. Arch Biochem Biophys (2012) 1.45
Tight junctions at the blood brain barrier: physiological architecture and disease-associated dysregulation. Fluids Barriers CNS (2012) 1.44
Bin1 attenuation suppresses experimental colitis by enforcing intestinal barrier function. Dig Dis Sci (2012) 1.40
Discovering the molecular components of intercellular junctions--a historical view. Cold Spring Harb Perspect Biol (2009) 1.39
GEF-H1 mediated control of NOD1 dependent NF-kappaB activation by Shigella effectors. PLoS Pathog (2008) 1.31
Role of TNF-alpha in lung tight junction alteration in mouse model of acute lung inflammation. Respir Res (2007) 1.29
Expression of occludin, tight-junction-associated protein, in human digestive tract. Am J Pathol (1997) 1.28
The organization of tight junctions in epithelia: implications for mammary gland biology and breast tumorigenesis. J Mammary Gland Biol Neoplasia (2003) 1.18
Occludin 1B, a variant of the tight junction protein occludin. Mol Biol Cell (2000) 1.16
Human astrocytes/astrocyte-conditioned medium and shear stress enhance the barrier properties of human brain microvascular endothelial cells. Brain Res (2007) 1.11
Characterisation of adherens and tight junctional molecules in normal animal larynx; determining a suitable model for studying molecular abnormalities in human laryngopharyngeal reflux. J Clin Pathol (2005) 1.10
EFA6, exchange factor for ARF6, regulates the actin cytoskeleton and associated tight junction in response to E-cadherin engagement. Mol Biol Cell (2003) 1.07
Ion transport by pulmonary epithelia. J Biomed Biotechnol (2011) 1.05
Hyperoxia disrupts pulmonary epithelial barrier in newborn rats via the deterioration of occludin and ZO-1. Respir Res (2012) 1.01
Role of vascular endothelial cell growth factor in Ovarian Hyperstimulation Syndrome. J Clin Invest (1998) 1.01
Normal establishment of epithelial tight junctions in mice and cultured cells lacking expression of ZO-3, a tight-junction MAGUK protein. Mol Cell Biol (2006) 1.01
Glycoprotein E of varicella-zoster virus enhances cell-cell contact in polarized epithelial cells. J Virol (2000) 1.00
Similar and distinct properties of MUPP1 and Patj, two homologous PDZ domain-containing tight-junction proteins. Mol Cell Biol (2009) 1.00
Influence of topical rectal application of drugs on dextran sulfate-induced colitis in rats. Dig Dis Sci (1997) 0.97
Renal defects associated with improper polarization of the CRB and DLG polarity complexes in MALS-3 knockout mice. J Cell Biol (2007) 0.97
Elucidating multiscale periosteal mechanobiology: a key to unlocking the smart properties and regenerative capacity of the periosteum? Tissue Eng Part B Rev (2013) 0.97
Transcriptional control of tight junction proteins via a protein kinase C signal pathway in human telomerase reverse transcriptase-transfected human pancreatic duct epithelial cells. Am J Pathol (2010) 0.95
Selectivity of lingual nerve fibers to chemical stimuli. J Gen Physiol (1993) 0.94
Cross-talk between pulmonary injury, oxidant stress, and gap junctional communication. Antioxid Redox Signal (2009) 0.94
A nuclear factor-κB signaling pathway via protein kinase C δ regulates replication of respiratory syncytial virus in polarized normal human nasal epithelial cells. Mol Biol Cell (2011) 0.92
Transcriptional changes in adhesion-related genes are site-specific during noise-induced cochlear pathogenesis. Neurobiol Dis (2011) 0.92
Protein kinase C activation has distinct effects on the localization, phosphorylation and detergent solubility of the claudin protein family in tight and leaky epithelial cells. J Membr Biol (2010) 0.91
Structure and composition of pulmonary arteries, capillaries, and veins. Compr Physiol (2012) 0.91
Tight junctions in inflammatory bowel diseases and inflammatory bowel disease associated colorectal cancer. World J Gastroenterol (2016) 0.87
Bacterial induction of Snail1 contributes to blood-brain barrier disruption. J Clin Invest (2015) 0.87
Tight junctions in human pancreatic duct epithelial cells. Tissue Barriers (2013) 0.87
Effects of oral glutamine supplementation on exercise-induced gastrointestinal permeability and tight junction protein expression. J Appl Physiol (1985) (2013) 0.87
Genetic deletion of afadin causes hydrocephalus by destruction of adherens junctions in radial glial and ependymal cells in the midbrain. PLoS One (2013) 0.86
Regulation of tight junctions in upper airway epithelium. Biomed Res Int (2012) 0.86
Acoustic overstimulation modifies Mcl-1 expression in cochlear sensory epithelial cells. J Neurosci Res (2010) 0.86
Deafness in occludin-deficient mice with dislocation of tricellulin and progressive apoptosis of the hair cells. Biol Open (2014) 0.86
Displayed correlation between gene expression profiles and submicroscopic alterations in response to cetuximab, gefitinib and EGF in human colon cancer cell lines. BMC Cancer (2008) 0.85
Age- and diet-related increase in transepithelial colon permeability of Fischer 344 rats. Dig Dis Sci (2002) 0.83
Adult neurogenesis: ultrastructure of a neurogenic niche and neurovascular relationships. PLoS One (2012) 0.82
Targeting tight junctions during epithelial to mesenchymal transition in human pancreatic cancer. World J Gastroenterol (2014) 0.82
Histamine reduces ZO-1 tight-junction protein expression in cultured retinal microvascular endothelial cells. Biochem J (1996) 0.82
Behavior of tricellulin during destruction and formation of tight junctions under various extracellular calcium conditions. Cell Tissue Res (2012) 0.82
Modeling tight junction dynamics and oscillations. J Gen Physiol (2002) 0.82
Curcumin prevents replication of respiratory syncytial virus and the epithelial responses to it in human nasal epithelial cells. PLoS One (2013) 0.81
Epidermal growth factor modulates claudins and tight junctional functions in ovarian cancer cell lines. Histochem Cell Biol (2012) 0.81
Aberrant expression of claudin-4 and -7 in hepatocytes in the cirrhotic human liver. Med Mol Morphol (2014) 0.81
The claudin Megatrachea protein complex. J Biol Chem (2012) 0.80
Peroxisome proliferator-activated receptor-γ agonists attenuate biofilm formation by Pseudomonas aeruginosa. FASEB J (2017) 0.79
Ciliary Body and Ciliary Epithelium. Adv Organ Biol (2005) 0.79
The tight junctional protein occludin is found in the uterine epithelium of squamate reptiles. J Comp Physiol B (2007) 0.79
Interferon-gamma increased epithelial barrier function via upregulating claudin-7 expression in human submandibular gland duct epithelium. J Mol Histol (2016) 0.78
Changes of gap and tight junctions during differentiation of human nasal epithelial cells using primary human nasal epithelial cells and primary human nasal fibroblast cells in a noncontact coculture system. J Membr Biol (2007) 0.78
Transcriptional regulators of claudins in epithelial tight junctions. Mediators Inflamm (2015) 0.78
Amastin Knockdown in Leishmania braziliensis Affects Parasite-Macrophage Interaction and Results in Impaired Viability of Intracellular Amastigotes. PLoS Pathog (2015) 0.78
Expression of tight junction proteins in epithelium including Ck20-positive M-like cells of human adenoids in vivo and in vitro. J Mol Histol (2008) 0.78
Tight junction physiology of pleural mesothelium. Front Physiol (2014) 0.78
The degradation of airway tight junction protein under acidic conditions is probably mediated by transient receptor potential vanilloid 1 receptor. Biosci Rep (2013) 0.78
Glucocorticoids and endothelial cell barrier function. Cell Tissue Res (2013) 0.78
Nasal potential difference to detect Na+ channel dysfunction in acute lung injury. Am J Physiol Lung Cell Mol Physiol (2010) 0.77
Elevated pressure downregulates ZO-1 expression and disrupts cytoskeleton and focal adhesion in human trabecular meshwork cells. Mol Vis (2011) 0.77
Occludin is a functional component of the tight junction. J Cell Sci (1996) 3.90
Arterial infections due to Listeria monocytogenes: report of four cases and review of world literature. Clin Infect Dis (1992) 1.94
Inducible expression of claudin-1-myc but not occludin-VSV-G results in aberrant tight junction strand formation in MDCK cells. J Cell Sci (2000) 1.58
Rapid reduction of MDCK cell cholesterol by methyl-beta-cyclodextrin alters steady state transepithelial electrical resistance. Eur J Cell Biol (1999) 1.37
Tight junctions. Their structure, composition, and function. Circ Res (1984) 1.14
Dimensions of LSD, methylphenidate and chlordiazepoxide experiences. Psychopharmacologia (1969) 0.97
Decrease in adhesion of cells cultured in polyunsaturated fatty acids. Cell (1977) 0.96
Myocardial revascularization by transmyocardial acupuncture. A physiologic impossibility. J Thorac Cardiovasc Surg (1969) 0.95
Traumatic splenic cyst: radiologic-pathologic correlation from the Armed Forces Institute of Pathology. Radiology (1980) 0.91
Formation and disappearance of triglyceride droplets in strain L fibroblasts. An electron microscopic study. Exp Cell Res (1971) 0.87
Alterations in cell cholesterol content modulate Ca(2+)-induced tight junction assembly by MDCK cells. Lipids (1996) 0.86
Glutaraldehyde fixation used to demonstrate altered properties of outer mitochondrial membranes in polyunsaturated fatty acid (PUFA) supplemented cells. Exp Cell Res (1976) 0.86
Mortality and lung histopathology after inhalation lung injury. The effect of corticosteroids. Am Rev Respir Dis (1986) 0.85
Inferior vena cava duplication: demonstration by computed tomography. Radiology (1979) 0.82
Complete avulsion of the axillary artery as a complication of shoulder dislocation. J Bone Joint Surg Am (1973) 0.82
Cerebral granulomatous angiitis: case report and literature review. AJR Am J Roentgenol (1977) 0.78
Interaction of plasma proteins with negatively charged sites on the pulmonary capillary endothelium of the rat. Cell Tissue Res (1988) 0.78
Modulation of tight junction formation in clone 4 MDCK cells by fatty acid supplementation. Am J Physiol (1988) 0.78
Alterations in L fibroblast lipid metabolism and morphology during choline deprivation. Exp Cell Res (1979) 0.77
Utilization of polyunsaturated fatty acids by human diploid cells aging in vitro. Lipids (1980) 0.76
Interaction of native and chemically modified albumin with pulmonary microvascular endothelium. Am J Physiol (1990) 0.76
Metabolism and incorporation into glycerolipids of exogenous 18:3(n-3) and 18:3(n-6) by MDCK cells. Lipids (1986) 0.76
Pulmonary carcinoid tumors: experience at one hospital for a 12-year period. Nebr Med J (1984) 0.75
The human right of bonding for warehoused "AIDS babies". Fam Community Health (1989) 0.75
A history of surgery in Nebraska. Nebr State Med J (1968) 0.75
High frequency jet ventilation in tracheopleural fistula: case report. Tex Med (1985) 0.75
Percutaneous transluminal angioplasty (PTA) and the community hospital: experience with 126 cases. J Am Osteopath Assoc (1981) 0.75
Optically active amines. 22. Application of the salicylidenimino chirality rule to alpha-amino acids. J Am Chem Soc (1977) 0.75
Reduction of adenine nucleotide content of clone 4 MDCK cells: effects on multiplication, protein synthesis, and morphology. J Cell Physiol (1989) 0.75
In memoriam--William Lete Shearer. Nebr Med J (1972) 0.75
Focal dermal hypoplasia (Goltz's syndrome) with an expansile iliac lesion. A case report. J Bone Joint Surg Am (1981) 0.75
Utilization of exogenous linolenic and oleic acids for plasma membrane phosphoglyceride synthesis in L-fibroblasts. Biochim Biophys Acta (1977) 0.75
Vein bypass grafts to the arteries of the leg and ankle. Nebr Med J (1972) 0.75
Direct coronary artery surgery with distal coronary artery perfusion. J Thorac Cardiovasc Surg (1970) 0.75
The celiac axis compression syndrome: review of the literature and report of a case. J Am Osteopath Assoc (1976) 0.75
L fibroblast phospholipid acyl group composition and triacylglycerol levels: response to continuous fatty acid infusion. Proc Soc Exp Biol Med (1981) 0.75
Uptake of rac-glycerol i-oleate and its utilization for glycerolipid synthesis by strain L fibroblasts. Biochim Biophys Acta (1972) 0.75
Myocardial revascularization: a combined approach. Chest (1970) 0.75
The use of perfluorochemical emulsion in the study of pulmonary microvascular permeability. Biomater Artif Cells Artif Organs (1988) 0.75
Inhibition of adenine nucleotide synthesis: effect on tight junction structure and function of clone 4 MDCK cells. Eur J Cell Biol (1991) 0.75
The hydrolysis of rac-glycerol 1-monodecanoate by serum butyryl cholinesterase. Arch Biochem Biophys (1972) 0.75
Diagnosis and treatment of pulmonary disorders of patients with the acquired immunodeficiency syndrome (AIDS). Z Erkr Atmungsorgane (1989) 0.75
Anomalous lateral and inferior position of the external carotid artery: case report. J Can Assoc Radiol (1975) 0.75
The microcirculation of the transplanted heart. J Thorac Cardiovasc Surg (1969) 0.75
Complete retention of phospholipid acyl groups by mammalian cells in culture. Biochemistry (1976) 0.75
Incorporation of [3H]acetate into L-cell lipids. Dependence on method of linoleate administration and timing of the pulse label. Biochim Biophys Acta (1981) 0.75