Endothelial claudin: claudin-5/TMVCF constitutes tight junction strands in endothelial cells.

PubWeight™: 3.78‹?› | Rank: Top 1%

🔗 View Article (PMC 2164984)

Published in J Cell Biol on October 04, 1999

Authors

K Morita1, H Sasaki, M Furuse, S Tsukita

Author Affiliations

1: Department of Cell Biology, Faculty of Medicine, Kyoto University, Kyoto 606-8501, Japan.

Articles citing this

(truncated to the top 100)

Size-selective loosening of the blood-brain barrier in claudin-5-deficient mice. J Cell Biol (2003) 5.74

Claudin-based tight junctions are crucial for the mammalian epidermal barrier: a lesson from claudin-1-deficient mice. J Cell Biol (2002) 5.51

Complex phenotype of mice lacking occludin, a component of tight junction strands. Mol Biol Cell (2000) 4.69

Continuous single-cell imaging of blood generation from haemogenic endothelium. Nature (2009) 4.32

Conversion of zonulae occludentes from tight to leaky strand type by introducing claudin-2 into Madin-Darby canine kidney I cells. J Cell Biol (2001) 3.66

Regulated expression of claudin-4 decreases paracellular conductance through a selective decrease in sodium permeability. J Clin Invest (2001) 3.28

Pores in the wall: claudins constitute tight junction strands containing aqueous pores. J Cell Biol (2000) 2.62

VEGF-mediated disruption of endothelial CLN-5 promotes blood-brain barrier breakdown. Proc Natl Acad Sci U S A (2009) 2.25

A gene signature predictive for outcome in advanced ovarian cancer identifies a survival factor: microfibril-associated glycoprotein 2. Cancer Cell (2009) 2.13

Slit diaphragms contain tight junction proteins. J Am Soc Nephrol (2009) 2.08

The mouse blood-brain barrier transcriptome: a new resource for understanding the development and function of brain endothelial cells. PLoS One (2010) 2.06

Claudins and the modulation of tight junction permeability. Physiol Rev (2013) 2.05

Molecular basis of the core structure of tight junctions. Cold Spring Harb Perspect Biol (2010) 1.87

Rho-mediated regulation of tight junctions during monocyte migration across the blood-brain barrier in HIV-1 encephalitis (HIVE). Blood (2006) 1.85

Occludin phosphorylation and ubiquitination regulate tight junction trafficking and vascular endothelial growth factor-induced permeability. J Biol Chem (2009) 1.81

Tight junctions in Schwann cells of peripheral myelinated axons: a lesson from claudin-19-deficient mice. J Cell Biol (2005) 1.69

TGF-beta receptor kinase inhibitor enhances growth and integrity of embryonic stem cell-derived endothelial cells. J Cell Biol (2003) 1.66

Dynamic behavior of paired claudin strands within apposing plasma membranes. Proc Natl Acad Sci U S A (2003) 1.66

Tight junction protein expression and barrier properties of immortalized mouse brain microvessel endothelial cells. Brain Res (2006) 1.65

Deficiency of zonula occludens-1 causes embryonic lethal phenotype associated with defected yolk sac angiogenesis and apoptosis of embryonic cells. Mol Biol Cell (2008) 1.63

Distinct claudins and associated PDZ proteins form different autotypic tight junctions in myelinating Schwann cells. J Cell Biol (2002) 1.60

Hypoxia disrupts the barrier function of neural blood vessels through changes in the expression of claudin-5 in endothelial cells. Am J Pathol (2007) 1.54

VE-cadherin: at the front, center, and sides of endothelial cell organization and function. Curr Opin Cell Biol (2010) 1.49

Functional effectiveness of the blood-brain barrier to small water-soluble molecules in developing and adult opossum (Monodelphis domestica). J Comp Neurol (2006) 1.48

Glucocorticoid induction of occludin expression and endothelial barrier requires transcription factor p54 NONO. Invest Ophthalmol Vis Sci (2013) 1.46

Blood-brain barrier breakdown in septic encephalopathy and brain tumours. J Anat (2002) 1.44

Tight junctions at the blood brain barrier: physiological architecture and disease-associated dysregulation. Fluids Barriers CNS (2012) 1.44

Chemokines, chemokine receptors and adhesion molecules on different human endothelia: discriminating the tissue-specific functions that affect leucocyte migration. Clin Exp Immunol (2003) 1.39

Discovering the molecular components of intercellular junctions--a historical view. Cold Spring Harb Perspect Biol (2009) 1.39

Dehydroepiandrosterone Sulfate Stimulates Expression of Blood-Testis-Barrier Proteins Claudin-3 and -5 and Tight Junction Formation via a Gnα11-Coupled Receptor in Sertoli Cells. PLoS One (2016) 1.39

Brain endothelial cell-cell junctions: how to "open" the blood brain barrier. Curr Neuropharmacol (2008) 1.38

Endothelial signaling in paracellular and transcellular leukocyte transmigration. Front Biosci (Landmark Ed) (2009) 1.31

Stepwise recruitment of transcellular and paracellular pathways underlies blood-brain barrier breakdown in stroke. Neuron (2014) 1.30

Selective decrease in paracellular conductance of tight junctions: role of the first extracellular domain of claudin-5. Mol Cell Biol (2004) 1.29

Proinflammatory cytokines tumor necrosis factor-alpha and interferon-gamma alter tight junction structure and function in the rat parotid gland Par-C10 cell line. Am J Physiol Cell Physiol (2008) 1.28

Developmental timing of CCM2 loss influences cerebral cavernous malformations in mice. J Exp Med (2011) 1.25

Endothelial cell junctions and the regulation of vascular permeability and leukocyte transmigration. J Thromb Haemost (2008) 1.23

Acute minocycline treatment mitigates the symptoms of mild blast-induced traumatic brain injury. Front Neurol (2012) 1.20

The organization of tight junctions in epithelia: implications for mammary gland biology and breast tumorigenesis. J Mammary Gland Biol Neoplasia (2003) 1.18

Interendothelial claudin-5 expression depends on cerebral endothelial cell-matrix adhesion by β(1)-integrins. J Cereb Blood Flow Metab (2011) 1.17

Claudin-1 induced sealing of blood-brain barrier tight junctions ameliorates chronic experimental autoimmune encephalomyelitis. Acta Neuropathol (2011) 1.16

Occludin 1B, a variant of the tight junction protein occludin. Mol Biol Cell (2000) 1.16

claudin-18, a novel downstream target gene for the T/EBP/NKX2.1 homeodomain transcription factor, encodes lung- and stomach-specific isoforms through alternative splicing. Mol Cell Biol (2001) 1.14

Claudins 6, 9, and 13 are developmentally expressed renal tight junction proteins. Am J Physiol Renal Physiol (2006) 1.13

Alteration of cell-cell junctions in cultured human lymphatic endothelial cells with inflammatory cytokine stimulation. Lymphat Res Biol (2014) 1.13

Reduced expression of junctional adhesion molecule and platelet/endothelial cell adhesion molecule-1 (CD31) at human vascular endothelial junctions by cytokines tumor necrosis factor-alpha plus interferon-gamma Does not reduce leukocyte transmigration under flow. Am J Pathol (2001) 1.12

The biology of the desmosome-like junction a versatile anchoring junction and signal transducer in the seminiferous epithelium. Int Rev Cell Mol Biol (2011) 1.12

ETS-related gene (ERG) controls endothelial cell permeability via transcriptional regulation of the claudin 5 (CLDN5) gene. J Biol Chem (2012) 1.11

Interleukin-25 expressed by brain capillary endothelial cells maintains blood-brain barrier function in a protein kinase Cepsilon-dependent manner. J Biol Chem (2009) 1.11

The blood-brain barrier: an engineering perspective. Front Neuroeng (2013) 1.09

Claudin-1, -2, -3, -4, -5, and -7 in usual interstitial pneumonia and sarcoidosis. J Histochem Cytochem (2008) 1.08

Immunolocalization of tight junction proteins in the adult and developing human brain. Histochem Cell Biol (2004) 1.05

Cannabinoids inhibit HIV-1 Gp120-mediated insults in brain microvascular endothelial cells. J Immunol (2008) 1.02

Caffeine protects against disruptions of the blood-brain barrier in animal models of Alzheimer's and Parkinson's diseases. J Alzheimers Dis (2010) 1.01

Influenza infects lung microvascular endothelium leading to microvascular leak: role of apoptosis and claudin-5. PLoS One (2012) 1.01

The blood-brain barrier. Cold Spring Harb Perspect Biol (2015) 1.00

Phosphodiesterase-III inhibitor prevents hemorrhagic transformation induced by focal cerebral ischemia in mice treated with tPA. PLoS One (2010) 1.00

Acquired immunodeficiency syndrome and the blood-brain barrier. J Neurovirol (2009) 1.00

Complexity and developmental changes in the expression pattern of claudins at the blood-CSF barrier. Histochem Cell Biol (2012) 1.00

Claudins: control of barrier function and regulation in response to oxidant stress. Antioxid Redox Signal (2011) 1.00

Claudin-5 controls intercellular barriers of human dermal microvascular but not human umbilical vein endothelial cells. Arterioscler Thromb Vasc Biol (2013) 0.99

Mechanisms regulating endothelial permeability. Pulm Circ (2014) 0.99

Glucocorticoids induce transactivation of tight junction genes occludin and claudin-5 in retinal endothelial cells via a novel cis-element. Exp Eye Res (2008) 0.98

Guanine nucleotide-binding protein Gαi2: a new partner of claudin-5 that regulates tight junction integrity in human brain endothelial cells. J Cereb Blood Flow Metab (2012) 0.97

FTY720-induced human pulmonary endothelial barrier enhancement is mediated by c-Abl. Eur Respir J (2010) 0.97

Gene expression pattern in human brain endothelial cells in response to Neisseria meningitidis. Infect Immun (2006) 0.96

Regulation of the expression of the prostate-specific antigen by claudin-7. J Membr Biol (2003) 0.96

Claudin 5 expression in mouse seminiferous epithelium is dependent upon the transcription factor ets variant 5 and contributes to blood-testis barrier function. Biol Reprod (2009) 0.96

Visualization and quantitative analysis of reconstituted tight junctions using localization microscopy. PLoS One (2012) 0.94

Divergent expression of claudin -1, -3, -4, -5 and -7 in developing human lung. Respir Res (2010) 0.94

Epithelial and endothelial barriers in the olfactory region of the nasal cavity of the rat. Histochem Cell Biol (2008) 0.94

Claudin-5 is involved in breast cancer cell motility through the N-WASP and ROCK signalling pathways. J Exp Clin Cancer Res (2012) 0.94

Differential effects of HIF-1 inhibition by YC-1 on the overall outcome and blood-brain barrier damage in a rat model of ischemic stroke. PLoS One (2011) 0.94

Adrenomedullin improves the blood-brain barrier function through the expression of claudin-5. Cell Mol Neurobiol (2006) 0.93

Endothelial barriers: from hypothetical pores to membrane proteins. J Anat (2002) 0.93

Tight junctions in salivary epithelium. J Biomed Biotechnol (2010) 0.93

Human salivary gland branching morphogenesis: morphological localization of claudins and its parallel relation with developmental stages revealed by expression of cytoskeleton and secretion markers. Histochem Cell Biol (2007) 0.93

Deciphering the functional role of endothelial junctions by using in vivo models. EMBO Rep (2008) 0.92

"You Shall Not Pass"-tight junctions of the blood brain barrier. Front Neurosci (2014) 0.92

Claudins and alveolar epithelial barrier function in the lung. Ann N Y Acad Sci (2012) 0.92

Regulation of the inflammatory response of vascular endothelial cells by EPAC1. Br J Pharmacol (2012) 0.91

Protein kinase C activation has distinct effects on the localization, phosphorylation and detergent solubility of the claudin protein family in tight and leaky epithelial cells. J Membr Biol (2010) 0.91

Tissue-specific expression of the tight junction proteins claudins and occludin in the rat salivary glands. J Anat (2004) 0.91

Rapid remodeling of tight junctions during paracellular diapedesis in a human model of the blood-brain barrier. J Immunol (2014) 0.91

In vitro models of the blood-brain barrier: An overview of commonly used brain endothelial cell culture models and guidelines for their use. J Cereb Blood Flow Metab (2016) 0.90

Effects of neonatal systemic inflammation on blood-brain barrier permeability and behaviour in juvenile and adult rats. Cardiovasc Psychiatry Neurol (2011) 0.90

A role for Egfl7 during endothelial organization in the embryoid body model system. J Angiogenes Res (2010) 0.90

Expression of Tight Junction and Drug Efflux Transporter Proteins in an in vitro Model of Human Blood-Brain Barrier. Front Psychiatry (2012) 0.90

Chronic inflammatory demyelinating polyneuropathy: decreased claudin-5 and relocated ZO-1. J Neurol Neurosurg Psychiatry (2004) 0.90

The phenotype of the human materno-fetal endothelial barrier: molecular occupancy of paracellular junctions dictate permeability and angiogenic plasticity. J Anat (2002) 0.90

TNF causes changes in glomerular endothelial permeability and morphology through a Rho and myosin light chain kinase-dependent mechanism. Physiol Rep (2015) 0.90

Distribution of tight junction proteins in adult human salivary glands. J Histochem Cytochem (2008) 0.89

Claudins overexpression in ovarian cancer: potential targets for Clostridium Perfringens Enterotoxin (CPE) based diagnosis and therapy. Int J Mol Sci (2013) 0.89

Enterocytes' tight junctions: From molecules to diseases. World J Gastrointest Pathophysiol (2011) 0.89

Novel 3D analysis of Claudin-5 reveals significant endothelial heterogeneity among CNS microvessels. Microvasc Res (2012) 0.88

Transcriptional profiling of human cavernosal endothelial cells reveals distinctive cell adhesion phenotype and role for claudin 11 in vascular barrier function. Physiol Genomics (2009) 0.88

12/15-Lipoxygenase mediates high-fat diet-induced endothelial tight junction disruption and monocyte transmigration: a new role for 15(S)-hydroxyeicosatetraenoic acid in endothelial cell dysfunction. J Biol Chem (2013) 0.87

Paracellular tightness and claudin-5 expression is increased in the BCEC/astrocyte blood-brain barrier model by increasing media buffer capacity during growth. AAPS J (2010) 0.87

Claudins reign: The claudin/EMP/PMP22/γ channel protein family in C. elegans. Tissue Barriers (2013) 0.87

Barriers of the peripheral nerve. Tissue Barriers (2013) 0.87

Articles cited by this

Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature (1970) 1528.65

Efficient selection for high-expression transfectants with a novel eukaryotic vector. Gene (1991) 38.64

Junctional complexes in various epithelia. J Cell Biol (1963) 31.83

Occludin: a novel integral membrane protein localizing at tight junctions. J Cell Biol (1993) 10.65

Junctions between intimately apposed cell membranes in the vertebrate brain. J Cell Biol (1969) 10.33

Fine structural localization of a blood-brain barrier to exogenous peroxidase. J Cell Biol (1967) 9.74

Identification of ZO-1: a high molecular weight polypeptide associated with the tight junction (zonula occludens) in a variety of epithelia. J Cell Biol (1986) 8.74

Structure and function of intercellular junctions. Int Rev Cytol (1974) 8.14

Claudin-1 and -2: novel integral membrane proteins localizing at tight junctions with no sequence similarity to occludin. J Cell Biol (1998) 7.78

Claudin multigene family encoding four-transmembrane domain protein components of tight junction strands. Proc Natl Acad Sci U S A (1999) 5.54

Vasculogenesis. Annu Rev Cell Dev Biol (1995) 5.41

Functional dissociation of paracellular permeability and transepithelial electrical resistance and disruption of the apical-basolateral intramembrane diffusion barrier by expression of a mutant tight junction membrane protein. J Cell Biol (1996) 5.06

Further observations on the fine structure of freeze-cleaved tight junctions. J Cell Sci (1973) 4.66

A single gene product, claudin-1 or -2, reconstitutes tight junction strands and recruits occludin in fibroblasts. J Cell Biol (1998) 4.64

Structure, biochemistry, and assembly of epithelial tight junctions. Am J Physiol (1987) 4.58

Tight junctions and the molecular basis for regulation of paracellular permeability. Am J Physiol (1995) 4.37

Freeze-fracture replica electron microscopy combined with SDS digestion for cytochemical labeling of integral membrane proteins. Application to the immunogold labeling of intercellular junctional complexes. J Cell Sci (1995) 4.27

Structure, function, and regulation of cellular tight junctions. Am J Physiol (1992) 4.20

Occludin is a functional component of the tight junction. J Cell Sci (1996) 3.90

A synthetic peptide corresponding to the extracellular domain of occludin perturbs the tight junction permeability barrier. J Cell Biol (1997) 3.86

Cingulin, a new peripheral component of tight junctions. Nature (1988) 3.81

Occludin-deficient embryonic stem cells can differentiate into polarized epithelial cells bearing tight junctions. J Cell Biol (1998) 3.62

Identification of a 160-kDa polypeptide that binds to the tight junction protein ZO-1. Proc Natl Acad Sci U S A (1991) 3.60

Growth factors acting via endothelial cell-specific receptor tyrosine kinases: VEGFs, angiopoietins, and ephrins in vascular development. Genes Dev (1999) 3.35

Development of the blood-brain barrier. Trends Neurosci (1990) 3.34

The molecular organization of endothelial cell to cell junctions: differential association of plakoglobin, beta-catenin, and alpha-catenin with vascular endothelial cadherin (VE-cadherin). J Cell Biol (1995) 3.27

Occludin and claudins in tight-junction strands: leading or supporting players? Trends Cell Biol (1999) 3.23

Breaking through the tight junction barrier. J Cell Biol (1993) 3.01

ZO-3, a novel member of the MAGUK protein family found at the tight junction, interacts with ZO-1 and occludin. J Cell Biol (1998) 2.99

Occludin as a possible determinant of tight junction permeability in endothelial cells. J Cell Sci (1997) 2.97

Interspecies diversity of the occludin sequence: cDNA cloning of human, mouse, dog, and rat-kangaroo homologues. J Cell Biol (1996) 2.94

COOH terminus of occludin is required for tight junction barrier function in early Xenopus embryos. J Cell Biol (1997) 2.71

Assembly of the tight junction: the role of diacylglycerol. J Cell Biol (1993) 2.61

Symplekin, a novel type of tight junction plaque protein. J Cell Biol (1996) 2.58

Monoclonal antibody 7H6 reacts with a novel tight junction-associated protein distinct from ZO-1, cingulin and ZO-2. J Cell Biol (1993) 2.56

Mammalian occludin in epithelial cells: its expression and subcellular distribution. Eur J Cell Biol (1997) 2.46

Claudin-11/OSP-based tight junctions of myelin sheaths in brain and Sertoli cells in testis. J Cell Biol (1999) 2.40

Segmental differentiations of cell junctions in the vascular endothelium. The microvasculature. J Cell Biol (1975) 2.22

Overexpression of occludin, a tight junction-associated integral membrane protein, induces the formation of intracellular multilamellar bodies bearing tight junction-like structures. J Cell Sci (1996) 2.20

Occludin confers adhesiveness when expressed in fibroblasts. J Cell Sci (1997) 2.10

Vascular permeability factor/vascular endothelial cell growth factor-mediated permeability occurs through disorganization of endothelial junctional proteins. J Biol Chem (1998) 1.80

Routes and mechanism of fluid transport by epithelia. Annu Rev Physiol (1998) 1.77

Modulation of tight junction structure in blood-brain barrier endothelial cells. Effects of tissue culture, second messengers and cocultured astrocytes. J Cell Sci (1994) 1.70

Development of blood-brain barrier tight junctions in the rat cortex. Brain Res Dev Brain Res (1996) 1.49

Plugging the leaks. Proc Natl Acad Sci U S A (1999) 1.31

Endothelial cells: adhesion and tight junctions. Curr Opin Cell Biol (1992) 1.27

Complex tight junctions of epithelial and of endothelial cells in early foetal brain. J Neurocytol (1975) 1.20

Segmental differentiations of cell junctions in the vascular endothelium. Arteries and veins. J Cell Biol (1976) 1.19

Identification, characterization, and precise mapping of a human gene encoding a novel membrane-spanning protein from the 22q11 region deleted in velo-cardio-facial syndrome. Genomics (1997) 1.16

Molecular analyses of tight junction physiology: insights and paradoxes. J Membr Biol (1998) 1.15

Endothelial cell membranes: polarity of particles as seen by freeze-fracturing. Science (1973) 1.09

Differentiation of blood-brain barrier endothelial cells. Pathol Biol (Paris) (1998) 1.01

Structure of intercellular junctions in different segments of the intrapulmonary vasculature. Ann N Y Acad Sci (1982) 0.88

Brain capillary endothelial cells express MBEC1, a protein that is related to the Clostridium perfringens enterotoxin receptors. Lab Invest (1998) 0.84

Normal and abnormal development of the blood-brain barrier. Microsc Res Tech (1994) 0.81

Articles by these authors

Functional annotation of a full-length mouse cDNA collection. Nature (2001) 23.61

Occludin: a novel integral membrane protein localizing at tight junctions. J Cell Biol (1993) 10.65

Multifunctional strands in tight junctions. Nat Rev Mol Cell Biol (2001) 9.62

Claudin-1 and -2: novel integral membrane proteins localizing at tight junctions with no sequence similarity to occludin. J Cell Biol (1998) 7.78

Activation of the estrogen receptor through phosphorylation by mitogen-activated protein kinase. Science (1995) 6.37

Claudin multigene family encoding four-transmembrane domain protein components of tight junction strands. Proc Natl Acad Sci U S A (1999) 5.54

The Cognitive Abilities Screening Instrument (CASI): a practical test for cross-cultural epidemiological studies of dementia. Int Psychogeriatr (1994) 5.47

The 102 kd cadherin-associated protein: similarity to vinculin and posttranscriptional regulation of expression. Cell (1991) 5.27

Acquired growth hormone deficiency due to pituitary stalk transection after head trauma in childhood. Eur J Pediatr (1993) 5.16

Rho-kinase phosphorylates COOH-terminal threonines of ezrin/radixin/moesin (ERM) proteins and regulates their head-to-tail association. J Cell Biol (1998) 5.15

Direct binding of three tight junction-associated MAGUKs, ZO-1, ZO-2, and ZO-3, with the COOH termini of claudins. J Cell Biol (1999) 5.06

Direct association of occludin with ZO-1 and its possible involvement in the localization of occludin at tight junctions. J Cell Biol (1994) 5.01

Altered growth of human colon cancer cell lines disrupted at activated Ki-ras. Science (1993) 4.76

Complex phenotype of mice lacking occludin, a component of tight junction strands. Mol Biol Cell (2000) 4.69

A single gene product, claudin-1 or -2, reconstitutes tight junction strands and recruits occludin in fibroblasts. J Cell Biol (1998) 4.64

The 220-kD protein colocalizing with cadherins in non-epithelial cells is identical to ZO-1, a tight junction-associated protein in epithelial cells: cDNA cloning and immunoelectron microscopy. J Cell Biol (1993) 4.22

Cadherin-mediated cell-cell adhesion is perturbed by v-src tyrosine phosphorylation in metastatic fibroblasts. J Cell Biol (1992) 4.12

ERM family members as molecular linkers between the cell surface glycoprotein CD44 and actin-based cytoskeletons. J Cell Biol (1994) 4.09

Regulation mechanism of ERM (ezrin/radixin/moesin) protein/plasma membrane association: possible involvement of phosphatidylinositol turnover and Rho-dependent signaling pathway. J Cell Biol (1996) 4.06

Involvement of ZO-1 in cadherin-based cell adhesion through its direct binding to alpha catenin and actin filaments. J Cell Biol (1997) 4.00

The dynamic behavior of the APC-binding protein EB1 on the distal ends of microtubules. Curr Biol (2000) 3.98

Occludin is a functional component of the tight junction. J Cell Sci (1996) 3.90

Conversion of zonulae occludentes from tight to leaky strand type by introducing claudin-2 into Madin-Darby canine kidney I cells. J Cell Biol (2001) 3.66

Occludin-deficient embryonic stem cells can differentiate into polarized epithelial cells bearing tight junctions. J Cell Biol (1998) 3.62

Molecular linkage between cadherins and actin filaments in cell-cell adherens junctions. Curr Opin Cell Biol (1992) 3.61

Manner of interaction of heterogeneous claudin species within and between tight junction strands. J Cell Biol (1999) 3.57

Induction of polarized cell-cell association and retardation of growth by activation of the E-cadherin-catenin adhesion system in a dispersed carcinoma line. J Cell Biol (1994) 3.43

Ezrin/radixin/moesin (ERM) proteins bind to a positively charged amino acid cluster in the juxta-membrane cytoplasmic domain of CD44, CD43, and ICAM-2. J Cell Biol (1998) 3.39

Magnifying endoscopy combined with narrow band imaging system for early gastric cancer: correlation of vascular pattern with histopathology (including video). Endoscopy (2004) 3.36

Possible involvement of phosphorylation of occludin in tight junction formation. J Cell Biol (1997) 3.35

The roles of catenins in the cadherin-mediated cell adhesion: functional analysis of E-cadherin-alpha catenin fusion molecules. J Cell Biol (1994) 3.31

A 220-kD undercoat-constitutive protein: its specific localization at cadherin-based cell-cell adhesion sites. J Cell Biol (1991) 3.31

Cell-to-cell adherens junction formation and actin filament organization: similarities and differences between non-polarized fibroblasts and polarized epithelial cells. J Cell Sci (1995) 3.27

Real-time imaging of cell-cell adherens junctions reveals that Drosophila mesoderm invagination begins with two phases of apical constriction of cells. J Cell Sci (2001) 3.25

The FERM domain: a unique module involved in the linkage of cytoplasmic proteins to the membrane. Trends Biochem Sci (1998) 3.24

Occludin and claudins in tight-junction strands: leading or supporting players? Trends Cell Biol (1999) 3.23

Cytoplasmic regulation of the movement of E-cadherin on the free cell surface as studied by optical tweezers and single particle tracking: corralling and tethering by the membrane skeleton. J Cell Biol (1998) 3.23

Regulation of imprinted X-chromosome inactivation in mice by Tsix. Development (2001) 3.12

Parental-origin-specific epigenetic modification of the mouse H19 gene. Nature (1993) 3.11

The movement of membranous organelles in axons. Electron microscopic identification of anterogradely and retrogradely transported organelles. J Cell Biol (1980) 3.08

Direct interaction of the Rho GDP dissociation inhibitor with ezrin/radixin/moesin initiates the activation of the Rho small G protein. J Biol Chem (1997) 3.08

Identification of the spinocerebellar ataxia type 2 gene using a direct identification of repeat expansion and cloning technique, DIRECT. Nat Genet (1996) 3.07

Expression of DNA methyltransferases DNMT1, 3A, and 3B in normal hematopoiesis and in acute and chronic myelogenous leukemia. Blood (2001) 3.07

Microsatellite polymorphism in the heme oxygenase-1 gene promoter is associated with susceptibility to emphysema. Am J Hum Genet (2000) 3.06

A gene family consisting of ezrin, radixin and moesin. Its specific localization at actin filament/plasma membrane association sites. J Cell Sci (1992) 3.04

Clostridium perfringens enterotoxin fragment removes specific claudins from tight junction strands: Evidence for direct involvement of claudins in tight junction barrier. J Cell Biol (1999) 3.02

Occludin as a possible determinant of tight junction permeability in endothelial cells. J Cell Sci (1997) 2.97

Interspecies diversity of the occludin sequence: cDNA cloning of human, mouse, dog, and rat-kangaroo homologues. J Cell Biol (1996) 2.94

Perturbation of cell adhesion and microvilli formation by antisense oligonucleotides to ERM family members. J Cell Biol (1994) 2.93

Cadherin dysfunction in a human cancer cell line: possible involvement of loss of alpha-catenin expression in reduced cell-cell adhesiveness. Cancer Res (1992) 2.89

Submembranous junctional plaque proteins include potential tumor suppressor molecules. J Cell Biol (1993) 2.87

A new 82-kD barbed end-capping protein (radixin) localized in the cell-to-cell adherens junction: purification and characterization. J Cell Biol (1989) 2.84

Basal cell carcinomas in mice overexpressing Gli2 in skin. Nat Genet (2000) 2.82

Afadin: A novel actin filament-binding protein with one PDZ domain localized at cadherin-based cell-to-cell adherens junction. J Cell Biol (1997) 2.82

Specific deficit of the ON response in visual transmission by targeted disruption of the mGluR6 gene. Cell (1995) 2.81

Identification of Grf1 on mouse chromosome 9 as an imprinted gene by RLGS-M. Nat Genet (1996) 2.77

Amantadine and pneumonia. Lancet (1999) 2.69

Diminished Sonic hedgehog signaling and lack of floor plate differentiation in Gli2 mutant mice. Development (1998) 2.67

Pores in the wall: claudins constitute tight junction strands containing aqueous pores. J Cell Biol (2000) 2.62

Functional domains of alpha-catenin required for the strong state of cadherin-based cell adhesion. J Cell Biol (1999) 2.59

Multiple imprinted sense and antisense transcripts, differential methylation and tandem repeats in a putative imprinting control region upstream of mouse Igf2. Proc Natl Acad Sci U S A (1997) 2.52

Structural basis of the membrane-targeting and unmasking mechanisms of the radixin FERM domain. EMBO J (2000) 2.49

Mammalian occludin in epithelial cells: its expression and subcellular distribution. Eur J Cell Biol (1997) 2.46

Nodal is a novel TGF-beta-like gene expressed in the mouse node during gastrulation. Nature (1993) 2.45

Centriolar satellites: molecular characterization, ATP-dependent movement toward centrioles and possible involvement in ciliogenesis. J Cell Biol (1999) 2.40

Radixin is a novel member of the band 4.1 family. J Cell Biol (1991) 2.40

Claudin-11/OSP-based tight junctions of myelin sheaths in brain and Sertoli cells in testis. J Cell Biol (1999) 2.40

ACE inhibitors and pneumonia. Lancet (1998) 2.38

Enzymatic properties of de novo-type mouse DNA (cytosine-5) methyltransferases. Nucleic Acids Res (2001) 2.36

Treatment of hemoptysis patients by thrombin and fibrinogen-thrombin infusion therapy using a fiberoptic bronchoscope. Chest (1989) 2.36

Pro----leu change at position 102 of prion protein is the most common but not the sole mutation related to Gerstmann-Sträussler syndrome. Biochem Biophys Res Commun (1989) 2.35