Published in Cold Spring Harb Perspect Biol on September 01, 2009
Adherens junctions: from molecules to morphogenesis. Nat Rev Mol Cell Biol (2010) 3.97
Cardiac telocytes - their junctions and functional implications. Cell Tissue Res (2012) 2.25
Telocytes and putative stem cells in the lungs: electron microscopy, electron tomography and laser scanning microscopy. Cell Tissue Res (2011) 2.09
The secret life of α-catenin: moonlighting in morphogenesis. J Cell Biol (2011) 1.34
α-Actinin-4/FSGS1 is required for Arp2/3-dependent actin assembly at the adherens junction. J Cell Biol (2012) 1.22
The junctions that don't fit the scheme: special symmetrical cell-cell junctions of their own kind. Cell Tissue Res (2009) 1.03
A genome-wide screen identifies conserved protein hubs required for cadherin-mediated cell-cell adhesion. J Cell Biol (2014) 1.02
Memory of cell shape biases stochastic fate decision-making despite mitotic rounding. Nat Commun (2016) 1.02
Structure, function, and regulation of desmosomes. Prog Mol Biol Transl Sci (2013) 1.00
Biotin ligase tagging identifies proteins proximal to E-cadherin, including lipoma preferred partner, a regulator of epithelial cell-cell and cell-substrate adhesion. J Cell Sci (2013) 0.99
The actin cytoskeleton as a barrier to virus infection of polarized epithelial cells. Viruses (2011) 0.99
Evolution: functional evolution of nuclear structure. J Cell Biol (2011) 0.98
Classical and desmosomal cadherins at a glance. J Cell Sci (2012) 0.96
The association of microtubules with tight junctions is promoted by cingulin phosphorylation by AMPK. J Cell Biol (2013) 0.93
Novel mechanism of cytokine-induced disruption of epithelial barriers: Janus kinase and protein kinase D-dependent downregulation of junction protein expression. Tissue Barriers (2013) 0.92
Duodenal helminth infection alters barrier function of the colonic epithelium via adaptive immune activation. Infect Immun (2011) 0.91
Epithelial junctions and Rho family GTPases: the zonular signalosome. Small GTPases (2014) 0.91
E-N-cadherin heterodimers define novel adherens junctions connecting endoderm-derived cells. J Cell Biol (2011) 0.89
PERP regulates enamel formation via effects on cell-cell adhesion and gene expression. J Cell Sci (2011) 0.89
Specific conserved C-terminal amino acids of Caenorhabditis elegans HMP-1/α-catenin modulate F-actin binding independently of vinculin. J Biol Chem (2012) 0.87
Ultrastructural analysis reveals cAMP-dependent enhancement of microvascular endothelial barrier functions via Rac1-mediated reorganization of intercellular junctions. Am J Pathol (2011) 0.87
Cell-cell contact preserves cell viability via plakoglobin. PLoS One (2011) 0.87
The retinoblastoma tumor suppressor pathway modulates the invasiveness of ErbB2-positive breast cancer. Oncogene (2013) 0.86
Desmosomal molecules in and out of adhering junctions: normal and diseased States of epidermal, cardiac and mesenchymally derived cells. Dermatol Res Pract (2010) 0.86
The mechanotransduction machinery at work at adherens junctions. Integr Biol (Camb) (2015) 0.86
Cell-cell junction remodeling in the heart: possible role in cardiac conduction system function and arrhythmias? Life Sci (2011) 0.85
Cardiomyocyte growth and sarcomerogenesis at the intercalated disc. Cell Mol Life Sci (2013) 0.84
The plaque protein myozap identified as a novel major component of adhering junctions in endothelia of the blood and the lymph vascular systems. J Cell Mol Med (2012) 0.83
Gene Mutations Resulting in the Development of ARVC/D Could Affect Cells of the Cardiac Conduction System. Front Physiol (2012) 0.83
Breaking the Gingival Epithelial Barrier: Role of the Aggregatibacter actinomycetemcomitans Cytolethal Distending Toxin in Oral Infectious Disease. Cells (2014) 0.83
Adherens junctions remain dynamic. BMC Biol (2010) 0.83
Cell junction remodeling in gingival tissue exposed to a microbial toxin. J Dent Res (2013) 0.82
Systematic identification and characterization of novel human skin-associated genes encoding membrane and secreted proteins. PLoS One (2013) 0.81
Synaptopodin couples epithelial contractility to α-actinin-4-dependent junction maturation. J Cell Biol (2015) 0.80
Rap1 GTPase is required for mouse lens epithelial maintenance and morphogenesis. Dev Biol (2015) 0.80
Regulation of cadherin expression in nervous system development. Cell Adh Migr (2013) 0.79
Regulation of Adherens Junctions in Trabecular Meshwork Cells by Rac GTPase and their influence on Intraocular Pressure. J Ocul Biol (2013) 0.79
The neurobiology of imagination: possible role of interaction-dominant dynamics and default mode network. Front Psychol (2013) 0.78
Different roles of cadherins in the assembly and structural integrity of the desmosome complex. J Cell Sci (2014) 0.78
The cell-cell junctions of mammalian testes: I. The adhering junctions of the seminiferous epithelium represent special differentiation structures. Cell Tissue Res (2014) 0.78
The plasma membrane potential and the organization of the actin cytoskeleton of epithelial cells. Int J Cell Biol (2012) 0.78
Cadherin controls nectin recruitment into adherens junctions by remodeling the actin cytoskeleton. J Cell Sci (2014) 0.78
Plakophilin-2: a cell-cell adhesion plaque molecule of selective and fundamental importance in cardiac functions and tumor cell growth. Cell Tissue Res (2012) 0.78
Minireview: regulation of gap junction dynamics by nuclear hormone receptors and their ligands. Mol Endocrinol (2012) 0.78
Inhibition of Notch Signaling During Mouse Incisor Renewal Leads to Enamel Defects. J Bone Miner Res (2015) 0.77
Transmembrane protein PERP is a component of tessellate junctions and of other junctional and non-junctional plasma membrane regions in diverse epithelial and epithelium-derived cells. Cell Tissue Res (2013) 0.77
LI-cadherin cis-dimerizes in the plasma membrane Ca(2+) independently and forms highly dynamic trans-contacts. Cell Mol Life Sci (2012) 0.77
Plakophilin-3 is required for late embryonic amphibian development, exhibiting roles in ectodermal and neural tissues. PLoS One (2012) 0.77
Microtubules Inhibit E-Cadherin Adhesive Activity by Maintaining Phosphorylated p120-Catenin in a Colon Carcinoma Cell Model. PLoS One (2016) 0.76
hESC expansion and stemness are independent of connexin forty-three-mediated intercellular communication between hESCs and hASC feeder cells. PLoS One (2013) 0.76
Characterization of partially lifted cell sheets. Tissue Eng Part A (2014) 0.75
Minireview: Steroid/nuclear receptor-regulated dynamics of occluding and anchoring junctions. Mol Endocrinol (2014) 0.75
Claudin-21 Has a Paracellular Channel Role at Tight Junctions. Mol Cell Biol (2016) 0.75
Altered gene expression patterns during the initiation and promotion stages of neonatally diethylstilbestrol-induced hyperplasia/dysplasia/neoplasia in the hamster uterus. Reprod Toxicol (2014) 0.75
Structural and functional characterization of the α-catenin·β-catenin binding interface in Caenorhabditis elegans reveals conserved requirements for cell-cell adhesion in metazoans. J Biol Chem (2017) 0.75
Junctional complexes in various epithelia. J Cell Biol (1963) 31.83
Cell adhesion: the molecular basis of tissue architecture and morphogenesis. Cell (1996) 14.75
Occludin: a novel integral membrane protein localizing at tight junctions. J Cell Biol (1993) 10.65
The cytoplasmic domain of the cell adhesion molecule uvomorulin associates with three independent proteins structurally related in different species. EMBO J (1989) 10.05
Multifunctional strands in tight junctions. Nat Rev Mol Cell Biol (2001) 9.62
The cadherins: cell-cell adhesion molecules controlling animal morphogenesis. Development (1988) 8.84
Genetic manipulation of E-cadherin expression by epithelial tumor cells reveals an invasion suppressor role. Cell (1991) 8.75
Identification of ZO-1: a high molecular weight polypeptide associated with the tight junction (zonula occludens) in a variety of epithelia. J Cell Biol (1986) 8.74
E-cadherin-mediated cell-cell adhesion prevents invasiveness of human carcinoma cells. J Cell Biol (1991) 8.60
Structure and function of intercellular junctions. Int Rev Cytol (1974) 8.14
Directed actin polymerization is the driving force for epithelial cell-cell adhesion. Cell (2000) 8.13
A fine structural analysis of intercellular junctions in the mouse liver. J Cell Biol (1970) 7.95
Claudin-1 and -2: novel integral membrane proteins localizing at tight junctions with no sequence similarity to occludin. J Cell Biol (1998) 7.78
Alpha-catenin is a molecular switch that binds E-cadherin-beta-catenin and regulates actin-filament assembly. Cell (2005) 7.62
Three-dimensional structure of the armadillo repeat region of beta-catenin. Cell (1997) 7.35
A STUDY OF THE STRUCTURE AND DISTRIBUTION OF THE NEXUS. J Cell Biol (1964) 6.54
Dissecting tumor cell invasion: epithelial cells acquire invasive properties after the loss of uvomorulin-mediated cell-cell adhesion. J Cell Biol (1989) 6.31
Cadherins: a molecular family important in selective cell-cell adhesion. Annu Rev Biochem (1990) 6.13
Cell-adhesion molecule uvomorulin is localized in the intermediate junctions of adult intestinal epithelial cells. J Cell Biol (1985) 6.09
Paracellin-1, a renal tight junction protein required for paracellular Mg2+ resorption. Science (1999) 6.04
The gap junction communication channel. Cell (1996) 5.95
Loss of epithelial differentiation and gain of invasiveness correlates with tyrosine phosphorylation of the E-cadherin/beta-catenin complex in cells transformed with a temperature-sensitive v-SRC gene. J Cell Biol (1993) 5.86
Uvomorulin-catenin complex formation is regulated by a specific domain in the cytoplasmic region of the cell adhesion molecule. Proc Natl Acad Sci U S A (1990) 5.83
A homolog of the armadillo protein in Drosophila (plakoglobin) associated with E-cadherin. Science (1991) 5.71
Claudin multigene family encoding four-transmembrane domain protein components of tight junction strands. Proc Natl Acad Sci U S A (1999) 5.54
Alpha 1(E)-catenin is an actin-binding and -bundling protein mediating the attachment of F-actin to the membrane adhesion complex. Proc Natl Acad Sci U S A (1995) 5.54
Claudin-based tight junctions are crucial for the mammalian epidermal barrier: a lesson from claudin-1-deficient mice. J Cell Biol (2002) 5.51
Fracture faces of zonulae occludentes from "tight" and "leaky" epithelia. J Cell Biol (1973) 5.45
Cadherins in development: cell adhesion, sorting, and tissue morphogenesis. Genes Dev (2006) 5.45
The tight junction protein ZO-1 establishes a link between the transmembrane protein occludin and the actin cytoskeleton. J Biol Chem (1998) 5.34
The 102 kd cadherin-associated protein: similarity to vinculin and posttranscriptional regulation of expression. Cell (1991) 5.27
Connexin43: a protein from rat heart homologous to a gap junction protein from liver. J Cell Biol (1987) 5.22
Variations in tight and gap junctions in mammalian tissues. J Cell Biol (1972) 5.08
Characterization of L-CAM, a major cell adhesion molecule from embryonic liver cells. Proc Natl Acad Sci U S A (1983) 5.05
Direct association of occludin with ZO-1 and its possible involvement in the localization of occludin at tight junctions. J Cell Biol (1994) 5.01
Functional correlation between cell adhesive properties and some cell surface proteins. J Cell Biol (1977) 4.97
Junctional intercellular communication: the cell-to-cell membrane channel. Physiol Rev (1981) 4.95
The ultrastructure of the cat myocardium. I. Ventricular papillary muscle. J Cell Biol (1969) 4.92
A cell surface glycoprotein involved in the compaction of embryonal carcinoma cells and cleavage stage embryos. Cell (1980) 4.89
Identification and purification of a cell surface glycoprotein mediating intercellular adhesion in embryonic and adult tissue. Cell (1983) 4.81
Claudins and epithelial paracellular transport. Annu Rev Physiol (2006) 4.79
Cloning and expression of cDNA encoding a neural calcium-dependent cell adhesion molecule: its identity in the cadherin gene family. J Cell Biol (1988) 4.71
Molecular cloning of cDNA for rat liver gap junction protein. J Cell Biol (1986) 4.69
Complex phenotype of mice lacking occludin, a component of tight junction strands. Mol Biol Cell (2000) 4.69
Structure of the junction between communicating cells. Nature (1980) 4.68
A single gene product, claudin-1 or -2, reconstitutes tight junction strands and recruits occludin in fibroblasts. J Cell Biol (1998) 4.64
A repeating amino acid motif shared by proteins with diverse cellular roles. Cell (1994) 4.56
Connexins, connexons, and intercellular communication. Annu Rev Biochem (1996) 4.51
The ultrastructure of the nexus. A correlated thin-section and freeze-cleave study. J Cell Biol (1970) 4.48
Connections with connexins: the molecular basis of direct intercellular signaling. Eur J Biochem (1996) 4.36
E-cadherin and APC compete for the interaction with beta-catenin and the cytoskeleton. J Cell Biol (1994) 4.34
The 220-kD protein colocalizing with cadherins in non-epithelial cells is identical to ZO-1, a tight junction-associated protein in epithelial cells: cDNA cloning and immunoelectron microscopy. J Cell Biol (1993) 4.22
Occluding junction structure-function relationships in a cultured epithelial monolayer. J Cell Biol (1985) 4.21
Structure, function, and regulation of cellular tight junctions. Am J Physiol (1992) 4.20
ERM family members as molecular linkers between the cell surface glycoprotein CD44 and actin-based cytoskeletons. J Cell Biol (1994) 4.09
Regulation mechanism of ERM (ezrin/radixin/moesin) protein/plasma membrane association: possible involvement of phosphatidylinositol turnover and Rho-dependent signaling pathway. J Cell Biol (1996) 4.06
Plakoglobin: a protein common to different kinds of intercellular adhering junctions. Cell (1986) 4.01
The structure of cell adhesion molecule uvomorulin. Insights into the molecular mechanism of Ca2+-dependent cell adhesion. EMBO J (1987) 4.00
Tight junction proteins. Prog Biophys Mol Biol (2003) 3.98
Cadherin-catenin complex: protein interactions and their implications for cadherin function. J Cell Biochem (1996) 3.95
Mutations in the desmosomal protein plakophilin-2 are common in arrhythmogenic right ventricular cardiomyopathy. Nat Genet (2004) 3.88
Sequence analysis of a cDNA clone encoding the liver cell adhesion molecule, L-CAM. Proc Natl Acad Sci U S A (1987) 3.86
Identification of a putative cell adhesion domain of uvomorulin. EMBO J (1985) 3.85
Cingulin, a new peripheral component of tight junctions. Nature (1988) 3.81
Endothelial claudin: claudin-5/TMVCF constitutes tight junction strands in endothelial cells. J Cell Biol (1999) 3.78
Dissociation of Madin-Darby canine kidney epithelial cells by the monoclonal antibody anti-arc-1: mechanistic aspects and identification of the antigen as a component related to uvomorulin. J Cell Biol (1985) 3.77
Cadherin switching. J Cell Sci (2008) 3.70
Cadherins as modulators of cellular phenotype. Annu Rev Cell Dev Biol (2003) 3.67
Identification of a new catenin: the tyrosine kinase substrate p120cas associates with E-cadherin complexes. Mol Cell Biol (1994) 3.66
Occludin-deficient embryonic stem cells can differentiate into polarized epithelial cells bearing tight junctions. J Cell Biol (1998) 3.62
The uvomorulin-anchorage protein alpha catenin is a vinculin homologue. Proc Natl Acad Sci U S A (1991) 3.62
Defining interactions and distributions of cadherin and catenin complexes in polarized epithelial cells. J Cell Biol (1994) 3.61
Identification of a 160-kDa polypeptide that binds to the tight junction protein ZO-1. Proc Natl Acad Sci U S A (1991) 3.60
The segment polarity gene armadillo encodes a functionally modular protein that is the Drosophila homolog of human plakoglobin. Cell (1990) 3.57
Manner of interaction of heterogeneous claudin species within and between tight junction strands. J Cell Biol (1999) 3.57
Expression of N-cadherin adhesion molecules associated with early morphogenetic events in chick development. Nature (1986) 3.57
Molecular nature of the calcium-dependent cell-cell adhesion system in mouse teratocarcinoma and embryonic cells studied with a monoclonal antibody. Dev Biol (1984) 3.56
Phylogenetic analysis of the cadherin superfamily allows identification of six major subfamilies besides several solitary members. J Mol Biol (2000) 3.52
The tight junction protein ZO-1 is homologous to the Drosophila discs-large tumor suppressor protein of septate junctions. Proc Natl Acad Sci U S A (1993) 3.48
Nectin/PRR: an immunoglobulin-like cell adhesion molecule recruited to cadherin-based adherens junctions through interaction with Afadin, a PDZ domain-containing protein. J Cell Biol (1999) 3.47
Molecular organization of the uvomorulin-catenin complex. J Cell Biol (1992) 3.46
Uvomorulin: a nonintegral membrane protein of early mouse embryo. Proc Natl Acad Sci U S A (1983) 3.42
Autoantibodies against a novel epithelial cadherin in pemphigus vulgaris, a disease of cell adhesion. Cell (1991) 3.42
Gap junction structures. I. Correlated electron microscopy and x-ray diffraction. J Cell Biol (1977) 3.41
Molecular architecture of tight junctions. Annu Rev Physiol (1998) 3.40
Role of IQGAP1, a target of the small GTPases Cdc42 and Rac1, in regulation of E-cadherin- mediated cell-cell adhesion. Science (1998) 3.39
Possible involvement of phosphorylation of occludin in tight junction formation. J Cell Biol (1997) 3.35
Inhibition of RhoA by p120 catenin. Nat Cell Biol (2000) 3.33
The roles of catenins in the cadherin-mediated cell adhesion: functional analysis of E-cadherin-alpha catenin fusion molecules. J Cell Biol (1994) 3.31
A 220-kD undercoat-constitutive protein: its specific localization at cadherin-based cell-cell adhesion sites. J Cell Biol (1991) 3.31
Cell-to-cell adherens junction formation and actin filament organization: similarities and differences between non-polarized fibroblasts and polarized epithelial cells. J Cell Sci (1995) 3.27
The molecular organization of endothelial cell to cell junctions: differential association of plakoglobin, beta-catenin, and alpha-catenin with vascular endothelial cadherin (VE-cadherin). J Cell Biol (1995) 3.27
Rabbit antiserum against a purified surface glycoprotein decompacts mouse preimplantation embryos and reacts with specific adult tissues. Exp Cell Res (1984) 3.20
Nectin and afadin: novel organizers of intercellular junctions. J Cell Sci (2003) 3.19
Cell-cell interactions in early embryogenesis: a molecular approach to the role of calcium. Cell (1981) 3.18
cDNA cloning and sequencing of the protein-tyrosine kinase substrate, ezrin, reveals homology to band 4.1. EMBO J (1989) 3.10
Early epochal maps of two different cell adhesion molecules. Proc Natl Acad Sci U S A (1983) 3.06
A novel cadherin cell adhesion molecule: its expression patterns associated with implantation and organogenesis of mouse embryos. J Cell Biol (1986) 3.06
Physiology and function of the tight junction. Cold Spring Harb Perspect Biol (2009) 3.06
Tricellulin constitutes a novel barrier at tricellular contacts of epithelial cells. J Cell Biol (2005) 3.05