Published in J Pharmacol Exp Ther on September 15, 2005
Dual excitatory and inhibitory serotonergic inputs modulate egg laying in Caenorhabditis elegans. Genetics (2008) 1.05
Developmental profiles of neurotransmitter receptors in respiratory motor nuclei. Respir Physiol Neurobiol (2008) 0.94
Is there a correlation between intravaginal ejaculatory latency time and enuresis? An exploratory study. Cent European J Urol (2014) 0.83
Emerging pharmacological targets in overactive bladder therapy: experimental and clinical evidences. Int Urogynecol J Pelvic Floor Dysfunct (2008) 0.82
Ketanserin and Naftopidil Enhance the Potentiating Effect of Alpha-Methyl-Serotonin on the Neurally-Induced Contraction of Human Isolated Urinary Bladder Muscle Strips. Int Neurourol J (2017) 0.80
5-hydroxytryptamine induced relaxation in the pig urinary bladder neck. Br J Pharmacol (2009) 0.78
Demonstration of 5-HT(3) receptor function and expression in the mouse bladder. Naunyn Schmiedebergs Arch Pharmacol (2007) 0.77
Bladder smooth muscle strip contractility as a method to evaluate lower urinary tract pharmacology. J Vis Exp (2014) 0.77
Urinary incontinence induced by tramadol. Indian J Palliat Care (2013) 0.75
Crystal structure of a eukaryotic zinc-dependent histone deacetylase, human HDAC8, complexed with a hydroxamic acid inhibitor. Proc Natl Acad Sci U S A (2004) 3.27
Mast cell-dependent excitation of visceral-nociceptive sensory neurons in irritable bowel syndrome. Gastroenterology (2007) 2.63
Histone deacetylase and Cullin3-REN(KCTD11) ubiquitin ligase interplay regulates Hedgehog signalling through Gli acetylation. Nat Cell Biol (2010) 2.25
Structural and functional analysis of the human HDAC4 catalytic domain reveals a regulatory structural zinc-binding domain. J Biol Chem (2008) 2.09
Substrate binding to histone deacetylases as shown by the crystal structure of the HDAC8-substrate complex. EMBO Rep (2007) 2.01
HDAC2 blockade by nitric oxide and histone deacetylase inhibitors reveals a common target in Duchenne muscular dystrophy treatment. Proc Natl Acad Sci U S A (2008) 1.80
Enteric neuroplasticity evoked by inflammation. Auton Neurosci (2006) 1.55
Intestinal serotonin release, sensory neuron activation, and abdominal pain in irritable bowel syndrome. Am J Gastroenterol (2011) 1.41
Probing the elusive catalytic activity of vertebrate class IIa histone deacetylases. Bioorg Med Chem Lett (2008) 1.37
PP2A regulates HDAC4 nuclear import. Mol Biol Cell (2007) 1.34
Inhibition of class I histone deacetylase with an apicidin derivative prevents cardiac hypertrophy and failure. Cardiovasc Res (2008) 1.26
Nitric oxide modulates chromatin folding in human endothelial cells via protein phosphatase 2A activation and class II histone deacetylases nuclear shuttling. Circ Res (2007) 1.24
Clinical and morphofunctional features of idiopathic myenteric ganglionitis underlying severe intestinal motor dysfunction: a study of three cases. Am J Gastroenterol (2002) 1.22
Anti-HuD-induced neuronal apoptosis underlying paraneoplastic gut dysmotility. Gastroenterology (2003) 1.19
A series of novel, potent, and selective histone deacetylase inhibitors. Bioorg Med Chem Lett (2006) 1.10
Novel therapeutic targets for enteric nervous system disorders. Trends Pharmacol Sci (2007) 0.97
Discovery of salermide-related sirtuin inhibitors: binding mode studies and antiproliferative effects in cancer cells including cancer stem cells. J Med Chem (2012) 0.96
Alterations in colonic motility and relationship to pain in colonic diverticulosis. Clin Gastroenterol Hepatol (2005) 0.96
Sera of patients with celiac disease and neurologic disorders evoke a mitochondrial-dependent apoptosis in vitro. Gastroenterology (2007) 0.95
Loss of histone deacetylase 4 causes segregation defects during mitosis of p53-deficient human tumor cells. Cancer Res (2009) 0.94
The genetics of the serotonin transporter and irritable bowel syndrome. Trends Mol Med (2008) 0.92
Molecular insights into azumamide e histone deacetylases inhibitory activity. J Am Chem Soc (2007) 0.87
Galanin receptors in the rat gastrointestinal tract. Neuropeptides (2005) 0.86
Neurochemically distinct classes of myenteric neurons express the mu-opioid receptor in the guinea pig ileum. J Comp Neurol (2003) 0.86
Neurology and neuropathology of the pancreatic innervation. JOP (2002) 0.85
Facilitation of acetylcholine signaling by the dithiocarbamate fungicide propineb. Chem Res Toxicol (2002) 0.85
A structure-guided approach to an orthogonal estrogen-receptor-based gene switch activated by ligands suitable for in vivo studies. J Med Chem (2006) 0.85
N-methyl-D-aspartate receptors mediate endogenous opioid release in enteric neurons after abdominal surgery. Gastroenterology (2005) 0.85
Expression of galanin receptor messenger RNAs in different regions of the rat gastrointestinal tract. Peptides (2005) 0.82
Peristalsis regulation by tachykinin NK1 receptors in the rabbit isolated distal colon. Am J Physiol Gastrointest Liver Physiol (2003) 0.81
Intestinal dysmotility and enteric neurochemical changes in a Parkinson's disease rat model. Auton Neurosci (2012) 0.81
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Benzodeazaoxaflavins as sirtuin inhibitors with antiproliferative properties in cancer stem cells. J Med Chem (2012) 0.80
Identification of MK-5710 ((8aS)-8a-methyl-1,3-dioxo-2-[(1S,2R)-2-phenylcyclo- propyl]-N-(1-phenyl-1H-pyrazol-5-yl)hexahydro-imidazo[1,5-a]pyrazine-7(1H)-carboxamide), a potent smoothened antagonist for use in Hedgehog pathway dependent malignancies, part 2. Bioorg Med Chem Lett (2011) 0.79
Herpes simplex virus type 1 infection of the rat enteric nervous system evokes small-bowel neuromuscular abnormalities. Gastroenterology (2010) 0.78
Synthesis and biological activity of cyclotetrapeptide analogues of the natural HDAC inhibitor FR235222. Bioorg Med Chem (2010) 0.76
Skin equivalents: a tool for the discovery and validation of pharmacodynamic biomarkers. Cancer Invest (2013) 0.75
The proton pump inhibitor test for gastroesophageal reflux disease: optimal cut-off value and duration. Dig Liver Dis (2010) 0.75
Prokinetics in the treatment of acute intestinal pseudo-obstruction. IDrugs (2004) 0.75