Published in Biochemistry on October 04, 2005
Dihydrodipicolinate synthase from Thermotoga maritima. Biochem J (2006) 1.37
The purification, crystallization and preliminary X-ray diffraction analysis of dihydrodipicolinate synthase from Clostridium botulinum. Acta Crystallogr Sect F Struct Biol Cryst Commun (2008) 1.01
Structural and biochemical studies of human 4-hydroxy-2-oxoglutarate aldolase: implications for hydroxyproline metabolism in primary hyperoxaluria. PLoS One (2011) 1.00
Purification, crystallization and preliminary X-ray diffraction studies to near-atomic resolution of dihydrodipicolinate synthase from methicillin-resistant Staphylococcus aureus. Acta Crystallogr Sect F Struct Biol Cryst Commun (2008) 0.99
Native SILAC: metabolic labeling of proteins in prototroph microorganisms based on lysine synthesis regulation. Mol Cell Proteomics (2013) 0.94
Crystal, solution and in silico structural studies of dihydrodipicolinate synthase from the common grapevine. PLoS One (2012) 0.91
Structural and dynamic requirements for optimal activity of the essential bacterial enzyme dihydrodipicolinate synthase. PLoS Comput Biol (2012) 0.84
Crystallization of dihydrodipicolinate synthase from a clinical isolate of Streptococcus pneumoniae. Acta Crystallogr Sect F Struct Biol Cryst Commun (2009) 0.80
Cloning, expression, purification and crystallization of dihydrodipicolinate synthase from the grapevine Vitis vinifera. Acta Crystallogr Sect F Struct Biol Cryst Commun (2011) 0.79
Tetrahydrodipicolinate N-succinyltransferase and dihydrodipicolinate synthase from Pseudomonas aeruginosa: structure analysis and gene deletion. PLoS One (2012) 0.78
Cloning, expression, purification and crystallization of dihydrodipicolinate synthase from Agrobacterium tumefaciens. Acta Crystallogr Sect F Struct Biol Cryst Commun (2012) 0.76
Cloning to crystallization of dihydrodipicolinate synthase from the intracellular pathogen Legionella pneumophila. Acta Crystallogr Sect F Struct Biol Cryst Commun (2013) 0.75
Dynamic Modelling Reveals 'Hotspots' on the Pathway to Enzyme-Substrate Complex Formation. PLoS Comput Biol (2016) 0.75
Cloning, expression, purification, crystallization and X-ray diffraction analysis of dihydrodipicolinate synthase from the human pathogenic bacterium Bartonella henselae strain Houston-1 at 2.1 Å resolution. Acta Crystallogr F Struct Biol Commun (2016) 0.75
Inhibition of Mycobacterium tuberculosis dihydrodipicolinate synthase by alpha-ketopimelic acid and its other structural analogues. Sci Rep (2016) 0.75
Structure of dihydrodipicolinate synthase from the commensal bacterium Bacteroides thetaiotaomicron at 2.1 Å resolution. Acta Crystallogr F Struct Biol Commun (2015) 0.75
Crystal structure and in silico studies of dihydrodipicolinate synthase (DHDPS) from Aquifex aeolicus. Extremophiles (2014) 0.75
Inhibition of lysine biosynthesis: an evolving antibiotic strategy. Mol Biosyst (2007) 1.69
The crystal structure of three site-directed mutants of Escherichia coli dihydrodipicolinate synthase: further evidence for a catalytic triad. J Mol Biol (2004) 1.48
The crystal structures of native and (S)-lysine-bound dihydrodipicolinate synthase from Escherichia coli with improved resolution show new features of biological significance. Acta Crystallogr D Biol Crystallogr (2005) 1.47
Crystal structure and kinetic study of dihydrodipicolinate synthase from Mycobacterium tuberculosis. Biochem J (2008) 1.46
Structure and evolution of a novel dimeric enzyme from a clinically important bacterial pathogen. J Biol Chem (2008) 1.38
Dihydrodipicolinate synthase from Thermotoga maritima. Biochem J (2006) 1.37
Evolution of quaternary structure in a homotetrameric enzyme. J Mol Biol (2008) 1.12
Insight into the self-association of key enzymes from pathogenic species. Eur Biophys J (2005) 1.09
Microfluidic droplets: new integrated workflows for biological experiments. Curr Opin Chem Biol (2010) 1.03
Dihydrodipicolinate synthase (DHDPS) from Escherichia coli displays partial mixed inhibition with respect to its first substrate, pyruvate. Biochimie (2004) 1.03
Substrate-mediated stabilization of a tetrameric drug target reveals Achilles heel in anthrax. J Biol Chem (2009) 1.03
Inhibiting dihydrodipicolinate synthase across species: towards specificity for pathogens? Bioorg Med Chem Lett (2007) 1.01
Synergistic allostery, a sophisticated regulatory network for the control of aromatic amino acid biosynthesis in Mycobacterium tuberculosis. J Biol Chem (2010) 1.00
Purification, crystallization and preliminary X-ray diffraction studies to near-atomic resolution of dihydrodipicolinate synthase from methicillin-resistant Staphylococcus aureus. Acta Crystallogr Sect F Struct Biol Cryst Commun (2008) 0.99
A [2 x 2] nickel(ii) grid and a copper(ii) square result from differing binding modes of a pyrazine-based diamide ligand. Dalton Trans (2006) 0.99
Dihydrodipicolinate synthase is not inhibited by its substrate, (S)-aspartate beta-semialdehyde. Biochem J (2004) 0.98
One in a million: flow cytometric sorting of single cell-lysate assays in monodisperse picolitre double emulsion droplets for directed evolution. Anal Chem (2014) 0.98
Conserved main-chain peptide distortions: a proposed role for Ile203 in catalysis by dihydrodipicolinate synthase. Protein Sci (2008) 0.97
Amyloid fibrils as a nanoscaffold for enzyme immobilization. Biotechnol Prog (2010) 0.96
Substrate ambiguity and crystal structure of Pyrococcus furiosus 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase: an ancestral 3-deoxyald-2-ulosonate-phosphate synthase? Biochemistry (2005) 0.96
The preparation of (S)-aspartate semi-aldehyde appropriate for use in biochemical studies. Bioorg Med Chem Lett (2003) 0.95
Two new irreversible inhibitors of dihydrodipicolinate synthase: diethyl (E,E)-4-oxo-2,5-heptadienedioate and diethyl (E)-4-oxo-2-heptenedioate. Bioorg Med Chem Lett (2005) 0.93
Engineering allosteric control to an unregulated enzyme by transfer of a regulatory domain. Proc Natl Acad Sci U S A (2013) 0.92
Control of molecular architecture by the degree of deprotonation: self-assembled di- and tetranuclear copper(II) complexes of N,N'-bis(2-pyridylmethyl)pyrazine-2,3-dicarboxamide. Chem Commun (Camb) (2003) 0.92
Three sites and you are out: ternary synergistic allostery controls aromatic amino acid biosynthesis in Mycobacterium tuberculosis. J Mol Biol (2012) 0.92
Expression, purification, crystallization and preliminary X-ray diffraction analysis of dihydrodipicolinate synthase from Bacillus anthracis in the presence of pyruvate. Acta Crystallogr Sect F Struct Biol Cryst Commun (2009) 0.92
Immobilization of organophosphate hydrolase on an amyloid fibril nanoscaffold: towards bioremediation and chemical detoxification. Biotechnol Prog (2010) 0.92
Cloning and characterisation of dihydrodipicolinate synthase from the pathogen Neisseria meningitidis. Biochim Biophys Acta (2009) 0.92
Crystal, solution and in silico structural studies of dihydrodipicolinate synthase from the common grapevine. PLoS One (2012) 0.91
Conformationally constrained diketopimelic acid analogues as inhibitors of dihydrodipicolinate synthase. Bioorg Med Chem Lett (2007) 0.90
Exploring the dihydrodipicolinate synthase tetramer: how resilient is the dimer-dimer interface? Arch Biochem Biophys (2009) 0.90
The high-resolution structure of dihydrodipicolinate synthase from Escherichia coli bound to its first substrate, pyruvate. Acta Crystallogr Sect F Struct Biol Cryst Commun (2008) 0.89
A single mutation in the core domain of the lac repressor reduces leakiness. Microb Cell Fact (2013) 0.89
Dynamic cross-talk among remote binding sites: the molecular basis for unusual synergistic allostery. J Mol Biol (2011) 0.89
How essential is the 'essential' active-site lysine in dihydrodipicolinate synthase? Biochimie (2010) 0.89
Deletion and gene expression analyses define the paxilline biosynthetic gene cluster in Penicillium paxilli. Toxins (Basel) (2013) 0.88
A simple method to evaluate the biochemical compatibility of oil/surfactant mixtures for experiments in microdroplets. Lab Chip (2012) 0.88
Irreversible inhibition of dihydrodipicolinate synthase by 4-oxo-heptenedioic acid analogues. Bioorg Med Chem (2008) 0.88
The relationship between oligomeric state and protein function. Adv Exp Med Biol (2012) 0.87
Bovine β-lactoglobulin is dimeric under imitative physiological conditions: dissociation equilibrium and rate constants over the pH range of 2.5-7.5. Biophys J (2012) 0.86
Mechanistic implications of persulfenate and persulfide binding in the active site of cysteine dioxygenase. Biochemistry (2013) 0.86
Characterization of dihydrodipicolinate reductase from Thermotoga maritima reveals evolution of substrate binding kinetics. J Biochem (2008) 0.86
The impact of processing on the nutritional quality of food proteins. J AOAC Int (2005) 0.86
A tetrameric structure is not essential for activity in dihydrodipicolinate synthase (DHDPS) from Mycobacterium tuberculosis. Arch Biochem Biophys (2011) 0.86
Specificity versus catalytic potency: The role of threonine 44 in Escherichia coli dihydrodipicolinate synthase mediated catalysis. Biochimie (2009) 0.86
Formation of amyloid-like fibrils by ovalbumin and related proteins under conditions relevant to food processing. J Agric Food Chem (2007) 0.85
A fully unsupervised compartment-on-demand platform for precise nanoliter assays of time-dependent steady-state enzyme kinetics and inhibition. Anal Chem (2013) 0.85
Characterisation of the first enzymes committed to lysine biosynthesis in Arabidopsis thaliana. PLoS One (2012) 0.84
Mutating the tight-dimer interface of dihydrodipicolinate synthase disrupts the enzyme quaternary structure: toward a monomeric enzyme. Biochemistry (2008) 0.84
Heterocyclic inhibitors of dihydrodipicolinate synthase are not competitive. Bioorg Med Chem (2005) 0.83
Cloning, expression and crystallization of dihydrodipicolinate reductase from methicillin-resistant Staphylococcus aureus. Acta Crystallogr Sect F Struct Biol Cryst Commun (2009) 0.82
Characterization of the structure, expression and function of Pinus radiata D. Don arabinogalactan-proteins. Planta (2007) 0.82
Characterization of monomeric dihydrodipicolinate synthase variant reveals the importance of substrate binding in optimizing oligomerization. Biochim Biophys Acta (2011) 0.81
Self-assembly of star-shaped heteropoly-15-palladate(II). Dalton Trans (2009) 0.81
The role of quaternary structure in (beta/alpha)(8)-barrel proteins: evolutionary happenstance or a higher level of structure-function relationships? Org Biomol Chem (2009) 0.81
Disruption of quaternary structure in Escherichia coli dihydrodipicolinate synthase (DHDPS) generates a functional monomer that is no longer inhibited by lysine. Arch Biochem Biophys (2010) 0.81
Synthesis and characterization of the dicopper(II)-containing 22-palladate(II)[Cu(II)2Pd(II)22P(V)12O60(OH)8]20-. Angew Chem Int Ed Engl (2011) 0.81
The C-terminal regulatory domain is required for catalysis by Neisseria meningitidis alpha-isopropylmalate synthase. Biochem Biophys Res Commun (2010) 0.81
Peroxiredoxin is a versatile self-assembling tecton for protein nanotechnology. Biomacromolecules (2014) 0.81
Structural, kinetic and computational investigation of Vitis vinifera DHDPS reveals new insight into the mechanism of lysine-mediated allosteric inhibition. Plant Mol Biol (2013) 0.81
New insights into protein crosslinking via the Maillard reaction: structural requirements, the effect on enzyme function, and predicted efficacy of crosslinking inhibitors as anti-ageing therapeutics. Bioorg Med Chem (2003) 0.80
NMR studies uncover alternate substrates for dihydrodipicolinate synthase and suggest that dihydrodipicolinate reductase is also a dehydratase. J Med Chem (2010) 0.80
Substrate dynamics in enzyme action: rotations of monosaccharide subunits in the binding groove are essential for pectin methylesterase processivity. Biophys J (2013) 0.80
Cloning, expression, purification and crystallization of dihydrodipicolinate synthase from the psychrophile Shewanella benthica. Acta Crystallogr Sect F Struct Biol Cryst Commun (2010) 0.80
Enhanced molecular chaperone activity of the small heat-shock protein alphaB-cystallin following covalent immobilization onto a solid-phase support. Biopolymers (2011) 0.80
Structure of bovine beta-lactoglobulin (variant A) at very low ionic strength. J Struct Biol (2006) 0.80
The role of the Maillard reaction in the formation of flavour compounds in dairy products--not only a deleterious reaction but also a rich source of flavour compounds. Food Funct (2012) 0.79
New insights into the mechanism of dihydrodipicolinate synthase using isothermal titration calorimetry. Biochimie (2009) 0.79
Two-dimensional heisenberg antiferromagnets: syntheses, X-ray structures, and magnetic behavior of [Cu(pz)2](ClO4)2, [Cu(pz)2](BF4)2, and [Cu(pz)2(NO3)](PF6). Inorg Chem (2007) 0.79
Reversing evolution: re-establishing obligate metal ion dependence in a metal-independent KDO8P synthase. J Mol Biol (2009) 0.79
A continuous enzyme assay and characterisation of fructosyl amine oxidase enzymes (EC 1.5.3). Arch Biochem Biophys (2005) 0.78
The quaternary structure of Escherichia coli N-acetylneuraminate lyase is essential for functional expression. Biochem Biophys Res Commun (2009) 0.78
Photolabile protecting groups in metal-organic frameworks: preventing interpenetration and masking functional groups. Chem Commun (Camb) (2011) 0.78
"Dilysine trigger" in transferrins probed by mutagenesis of lactoferrin: crystal structures of the R210G, R210E, and R210L mutants of human lactoferrin. Biochemistry (2002) 0.78
Stereospecific deuteration of 2-deoxyerythrose 4-phosphate using 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase. Bioorg Med Chem Lett (2005) 0.77