Published in J Biol Chem on August 05, 2008
NUTS and BOLTS: applications of fluorescence-detected sedimentation. Anal Biochem (2008) 1.29
Substrate-mediated stabilization of a tetrameric drug target reveals Achilles heel in anthrax. J Biol Chem (2009) 1.03
Conserved main-chain peptide distortions: a proposed role for Ile203 in catalysis by dihydrodipicolinate synthase. Protein Sci (2008) 0.97
Crystallization and preliminary X-ray analysis of dihydrodipicolinate synthase from Clostridium botulinum in the presence of its substrate pyruvate. Acta Crystallogr Sect F Struct Biol Cryst Commun (2009) 0.94
Expression, purification, crystallization and preliminary X-ray diffraction analysis of dihydrodipicolinate synthase from Bacillus anthracis in the presence of pyruvate. Acta Crystallogr Sect F Struct Biol Cryst Commun (2009) 0.92
Crystal, solution and in silico structural studies of dihydrodipicolinate synthase from the common grapevine. PLoS One (2012) 0.91
L,L-diaminopimelate aminotransferase from Chlamydomonas reinhardtii: a target for algaecide development. PLoS One (2011) 0.88
Dimerization of bacterial diaminopimelate epimerase is essential for catalysis. J Biol Chem (2013) 0.88
Dissociation of the octameric enolase from S. pyogenes--one interface stabilizes another. PLoS One (2010) 0.87
Characterisation of the first enzymes committed to lysine biosynthesis in Arabidopsis thaliana. PLoS One (2012) 0.84
Structural and dynamic requirements for optimal activity of the essential bacterial enzyme dihydrodipicolinate synthase. PLoS Comput Biol (2012) 0.84
Cloning, expression and crystallization of dihydrodipicolinate reductase from methicillin-resistant Staphylococcus aureus. Acta Crystallogr Sect F Struct Biol Cryst Commun (2009) 0.82
Cloning, expression, purification, crystallization and preliminary X-ray diffraction studies of N-acetylneuraminate lyase from methicillin-resistant Staphylococcus aureus. Acta Crystallogr Sect F Struct Biol Cryst Commun (2013) 0.80
Crystallization of dihydrodipicolinate synthase from a clinical isolate of Streptococcus pneumoniae. Acta Crystallogr Sect F Struct Biol Cryst Commun (2009) 0.80
Cloning, expression, purification and crystallization of dihydrodipicolinate synthase from the psychrophile Shewanella benthica. Acta Crystallogr Sect F Struct Biol Cryst Commun (2010) 0.80
Crystallization and preliminary X-ray diffraction analysis of L,L-diaminopimelate aminotransferase (DapL) from Chlamydomonas reinhardtii. Acta Crystallogr Sect F Struct Biol Cryst Commun (2010) 0.79
Cloning, expression, purification and crystallization of dihydrodipicolinate synthase from the grapevine Vitis vinifera. Acta Crystallogr Sect F Struct Biol Cryst Commun (2011) 0.79
From knock-out phenotype to three-dimensional structure of a promising antibiotic target from Streptococcus pneumoniae. PLoS One (2013) 0.78
Tetrahydrodipicolinate N-succinyltransferase and dihydrodipicolinate synthase from Pseudomonas aeruginosa: structure analysis and gene deletion. PLoS One (2012) 0.78
Dimerization of Bacterial Diaminopimelate Decarboxylase Is Essential for Catalysis. J Biol Chem (2016) 0.76
Cloning, expression, purification and crystallization of dihydrodipicolinate synthase from Agrobacterium tumefaciens. Acta Crystallogr Sect F Struct Biol Cryst Commun (2012) 0.76
Crystallization and preliminary X-ray diffraction analysis of dihydrodipicolinate synthase 2 from Arabidopsis thaliana. Acta Crystallogr Sect F Struct Biol Cryst Commun (2011) 0.76
Cloning, expression, purification, crystallization and X-ray diffraction analysis of dihydrodipicolinate synthase from the human pathogenic bacterium Bartonella henselae strain Houston-1 at 2.1 Å resolution. Acta Crystallogr F Struct Biol Commun (2016) 0.75
Dynamic Modelling Reveals 'Hotspots' on the Pathway to Enzyme-Substrate Complex Formation. PLoS Comput Biol (2016) 0.75
Cloning to crystallization of dihydrodipicolinate synthase from the intracellular pathogen Legionella pneumophila. Acta Crystallogr Sect F Struct Biol Cryst Commun (2013) 0.75
Structure and Function of Cyanobacterial DHDPS and DHDPR. Sci Rep (2016) 0.75
Molecular and Structural Characterization of a Novel Escherichia coli Interleukin Receptor Mimic Protein. MBio (2016) 0.75
Crystal structure of the Leishmania major MIX protein: a scaffold protein that mediates protein-protein interactions. Protein Sci (2011) 0.75
Crystal structure and in silico studies of dihydrodipicolinate synthase (DHDPS) from Aquifex aeolicus. Extremophiles (2014) 0.75
Biophysical studies of an NAD(P)(+)-dependent aldehyde dehydrogenase from Bacillus licheniformis. Eur Biophys J (2011) 0.75
Use of fluorescence-detected sedimentation velocity to study high-affinity protein interactions. Nat Protoc (2017) 0.75
Size-distribution analysis of proteins by analytical ultracentrifugation: strategies and application to model systems. Biophys J (2002) 5.20
The pseudokinase MLKL mediates necroptosis via a molecular switch mechanism. Immunity (2013) 3.15
Siah ubiquitin ligase is structurally related to TRAF and modulates TNF-alpha signaling. Nat Struct Biol (2002) 2.32
Do current therapeutic anti-Aβ antibodies for Alzheimer's disease engage the target? Acta Neuropathol (2014) 2.25
AMPK beta subunit targets metabolic stress sensing to glycogen. Curr Biol (2003) 2.19
Human factor H-related protein 5 has cofactor activity, inhibits C3 convertase activity, binds heparin and C-reactive protein, and associates with lipoprotein. J Immunol (2005) 1.92
Model for growth hormone receptor activation based on subunit rotation within a receptor dimer. Nat Struct Mol Biol (2005) 1.83
The structure of the GM-CSF receptor complex reveals a distinct mode of cytokine receptor activation. Cell (2008) 1.83
Elucidation of the substrate binding site of Siah ubiquitin ligase. Structure (2006) 1.79
Anxiety over GABA(A) receptor structure relieved by AChBP. Trends Biochem Sci (2002) 1.74
Critical role for the second extracellular loop in the binding of both orthosteric and allosteric G protein-coupled receptor ligands. J Biol Chem (2007) 1.70
Inhibition of lysine biosynthesis: an evolving antibiotic strategy. Mol Biosyst (2007) 1.69
The granulocyte-macrophage colony-stimulating factor receptor: linking its structure to cell signaling and its role in disease. Blood (2009) 1.63
Molecular dissection of the interaction between amyloid precursor protein and its neuronal trafficking receptor SorLA/LR11. Biochemistry (2006) 1.63
Insights into the action of the superfamily of cholesterol-dependent cytolysins from studies of intermedilysin. Proc Natl Acad Sci U S A (2005) 1.63
Cytoplasmic ATP-sensing domains regulate gating of skeletal muscle ClC-1 chloride channels. J Biol Chem (2005) 1.62
Structures of perfringolysin O suggest a pathway for activation of cholesterol-dependent cytolysins. J Mol Biol (2007) 1.54
Structural basis for glycogen recognition by AMP-activated protein kinase. Structure (2005) 1.50
The crystal structure of three site-directed mutants of Escherichia coli dihydrodipicolinate synthase: further evidence for a catalytic triad. J Mol Biol (2004) 1.48
The crystal structures of native and (S)-lysine-bound dihydrodipicolinate synthase from Escherichia coli with improved resolution show new features of biological significance. Acta Crystallogr D Biol Crystallogr (2005) 1.47
An activation-specific platelet inhibitor that can be turned on/off by medically used hypothermia. Arterioscler Thromb Vasc Biol (2011) 1.46
Crystal structure and kinetic study of dihydrodipicolinate synthase from Mycobacterium tuberculosis. Biochem J (2008) 1.46
Rowe and Kahn's model of successful aging revisited: positive spirituality--the forgotten factor. Gerontologist (2002) 1.44
Intrasteric control of AMPK via the gamma1 subunit AMP allosteric regulatory site. Protein Sci (2004) 1.41
Oseltamivir resistance and the H274Y neuraminidase mutation in seasonal, pandemic and highly pathogenic influenza viruses. Drugs (2009) 1.41
Antigen ligation triggers a conformational change within the constant domain of the alphabeta T cell receptor. Immunity (2009) 1.40
The SOCS box domain of SOCS3: structure and interaction with the elonginBC-cullin5 ubiquitin ligase. J Mol Biol (2008) 1.39
Structure of the Alzheimer's disease amyloid precursor protein copper binding domain. A regulator of neuronal copper homeostasis. J Biol Chem (2003) 1.38
Dihydrodipicolinate synthase from Thermotoga maritima. Biochem J (2006) 1.37
The structural basis for autonomous dimerization of the pre-T-cell antigen receptor. Nature (2010) 1.35
Federated repositories of X-ray diffraction images. Acta Crystallogr D Biol Crystallogr (2008) 1.33
Inhibition of skeletal muscle ClC-1 chloride channels by low intracellular pH and ATP. J Biol Chem (2007) 1.32
A rivet model for channel formation by aerolysin-like pore-forming toxins. EMBO J (2006) 1.28
Molecular determinants of ginkgolide binding in the glycine receptor pore. J Neurochem (2006) 1.28
Tracking mutant huntingtin aggregation kinetics in cells reveals three major populations that include an invariant oligomer pool. J Biol Chem (2010) 1.28
The crystal structure of myelin oligodendrocyte glycoprotein, a key autoantigen in multiple sclerosis. Proc Natl Acad Sci U S A (2003) 1.24
The 2.1A crystal structure of the far-red fluorescent protein HcRed: inherent conformational flexibility of the chromophore. J Mol Biol (2005) 1.23
From glutathione transferase to pore in a CLIC. Eur Biophys J (2002) 1.23
The identification and structure of the membrane-spanning domain of the Clostridium septicum alpha toxin. J Biol Chem (2004) 1.22
Age-related differences in plasma proteins: how plasma proteins change from neonates to adults. PLoS One (2011) 1.22
The GM-CSF/IL-3/IL-5 cytokine receptor family: from ligand recognition to initiation of signaling. Immunol Rev (2012) 1.20
Amyloid-beta-anti-amyloid-beta complex structure reveals an extended conformation in the immunodominant B-cell epitope. J Mol Biol (2008) 1.17
Structural characterization of respiratory syncytial virus fusion inhibitor escape mutants: homology model of the F protein and a syncytium formation assay. Virology (2003) 1.17
Molecular characterisation of a novel cassava associated circular ssDNA virus. Virus Res (2012) 1.14
Altered kinetics and benzodiazepine sensitivity of a GABAA receptor subunit mutation [gamma 2(R43Q)] found in human epilepsy. Proc Natl Acad Sci U S A (2002) 1.14
Molecular evolution of glutathione S-transferases in the genus Drosophila. Genetics (2007) 1.14
Mapping the intermedilysin-human CD59 receptor interface reveals a deep correspondence with the binding site on CD59 for complement binding proteins C8alpha and C9. J Biol Chem (2011) 1.12
Evolution of quaternary structure in a homotetrameric enzyme. J Mol Biol (2008) 1.12
A family of helminth molecules that modulate innate cell responses via molecular mimicry of host antimicrobial peptides. PLoS Pathog (2011) 1.10
Methionine oxidation induces amyloid fibril formation by full-length apolipoprotein A-I. Proc Natl Acad Sci U S A (2010) 1.09
Insight into the self-association of key enzymes from pathogenic species. Eur Biophys J (2005) 1.09
Ribosome-inactivating proteins: current status and biomedical applications. Drug Discov Today (2012) 1.08
Role of arginine 138 in the catalysis and regulation of Escherichia coli dihydrodipicolinate synthase. Biochemistry (2005) 1.07
Solution conformation and heparin-induced dimerization of the full-length extracellular domain of the human amyloid precursor protein. J Mol Biol (2006) 1.07
Apolipoproteins and amyloid fibril formation in atherosclerosis. Protein Cell (2011) 1.07
Properties of GDP-mannose pyrophosphorylase, a critical enzyme and drug target in Leishmania mexicana. J Biol Chem (2004) 1.05
Insights into the structural basis for zinc inhibition of the glycine receptor. J Biol Chem (2003) 1.05
A proposed structural basis for picrotoxinin and picrotin binding in the glycine receptor pore. J Neurochem (2007) 1.04
Conversion of a transmembrane to a water-soluble protein complex by a single point mutation. Nat Struct Biol (2002) 1.04
Discovery of a novel circular single-stranded DNA virus from porcine faeces. Arch Virol (2012) 1.04
Solution conformation, backbone dynamics and lipid interactions of the intrinsically unstructured malaria surface protein MSP2. J Mol Biol (2008) 1.03
Novel Bcl-2 homology-3 domain-like sequences identified from screening randomized peptide libraries for inhibitors of the pro-survival Bcl-2 proteins. J Biol Chem (2009) 1.03
Dihydrodipicolinate synthase (DHDPS) from Escherichia coli displays partial mixed inhibition with respect to its first substrate, pyruvate. Biochimie (2004) 1.03
Substrate-mediated stabilization of a tetrameric drug target reveals Achilles heel in anthrax. J Biol Chem (2009) 1.03
Bapineuzumab captures the N-terminus of the Alzheimer's disease amyloid-beta peptide in a helical conformation. Sci Rep (2013) 1.02
Molecular basis of cytokine receptor activation. IUBMB Life (2010) 1.01
The purification, crystallization and preliminary X-ray diffraction analysis of dihydrodipicolinate synthase from Clostridium botulinum. Acta Crystallogr Sect F Struct Biol Cryst Commun (2008) 1.01
AMP-activated protein kinase subunit interactions: beta1:gamma1 association requires beta1 Thr-263 and Tyr-267. J Biol Chem (2007) 1.01
Structure of the Janus protein human CLIC2. J Mol Biol (2007) 1.01
Inhibiting dihydrodipicolinate synthase across species: towards specificity for pathogens? Bioorg Med Chem Lett (2007) 1.01
Synergistic allostery, a sophisticated regulatory network for the control of aromatic amino acid biosynthesis in Mycobacterium tuberculosis. J Biol Chem (2010) 1.00
The trans-Golgi network GRIP-domain proteins form alpha-helical homodimers. Biochem J (2005) 1.00
Determinants of DNA mismatch recognition within the polymerase domain of the Klenow fragment. Biochemistry (2002) 1.00
Purification, crystallization and preliminary X-ray diffraction studies to near-atomic resolution of dihydrodipicolinate synthase from methicillin-resistant Staphylococcus aureus. Acta Crystallogr Sect F Struct Biol Cryst Commun (2008) 0.99
A [2 x 2] nickel(ii) grid and a copper(ii) square result from differing binding modes of a pyrazine-based diamide ligand. Dalton Trans (2006) 0.99