Published in Bioorg Med Chem Lett on December 03, 2007
The high-resolution structure of dihydrodipicolinate synthase from Escherichia coli bound to its first substrate, pyruvate. Acta Crystallogr Sect F Struct Biol Cryst Commun (2008) 0.89
L,L-diaminopimelate aminotransferase from Chlamydomonas reinhardtii: a target for algaecide development. PLoS One (2011) 0.88
Crystallization and preliminary X-ray diffraction analysis of L,L-diaminopimelate aminotransferase (DapL) from Chlamydomonas reinhardtii. Acta Crystallogr Sect F Struct Biol Cryst Commun (2010) 0.79
Cloning, expression, purification and crystallization of dihydrodipicolinate synthase from the grapevine Vitis vinifera. Acta Crystallogr Sect F Struct Biol Cryst Commun (2011) 0.79
Crystallization and preliminary X-ray diffraction analysis of dihydrodipicolinate synthase 2 from Arabidopsis thaliana. Acta Crystallogr Sect F Struct Biol Cryst Commun (2011) 0.76
Inhibition of Mycobacterium tuberculosis dihydrodipicolinate synthase by alpha-ketopimelic acid and its other structural analogues. Sci Rep (2016) 0.75
The crystal structure of dihydrodipicolinate reductase from the human-pathogenic bacterium Bartonella henselae strain Houston-1 at 2.3 Å resolution. Acta Crystallogr F Struct Biol Commun (2016) 0.75
Transcriptional analysis of the conidiation pattern shift of the entomopathogenic fungus Metarhizium acridum in response to different nutrients. BMC Genomics (2016) 0.75
The purification, crystallization and preliminary X-ray diffraction analysis of two isoforms of meso-diaminopimelate decarboxylase from Arabidopsis thaliana. Acta Crystallogr F Struct Biol Commun (2014) 0.75
The pseudokinase MLKL mediates necroptosis via a molecular switch mechanism. Immunity (2013) 3.15
Inhibition of lysine biosynthesis: an evolving antibiotic strategy. Mol Biosyst (2007) 1.69
The crystal structure of three site-directed mutants of Escherichia coli dihydrodipicolinate synthase: further evidence for a catalytic triad. J Mol Biol (2004) 1.48
The crystal structures of native and (S)-lysine-bound dihydrodipicolinate synthase from Escherichia coli with improved resolution show new features of biological significance. Acta Crystallogr D Biol Crystallogr (2005) 1.47
Crystal structure and kinetic study of dihydrodipicolinate synthase from Mycobacterium tuberculosis. Biochem J (2008) 1.46
Structure and evolution of a novel dimeric enzyme from a clinically important bacterial pathogen. J Biol Chem (2008) 1.38
Dihydrodipicolinate synthase from Thermotoga maritima. Biochem J (2006) 1.37
Federated repositories of X-ray diffraction images. Acta Crystallogr D Biol Crystallogr (2008) 1.33
Molecular characterisation of a novel cassava associated circular ssDNA virus. Virus Res (2012) 1.14
Evolution of quaternary structure in a homotetrameric enzyme. J Mol Biol (2008) 1.12
Synthesis of the side chain cross-linked tyrosine oligomers dityrosine, trityrosine, and pulcherosine. J Org Chem (2005) 1.10
Insight into the self-association of key enzymes from pathogenic species. Eur Biophys J (2005) 1.09
Role of arginine 138 in the catalysis and regulation of Escherichia coli dihydrodipicolinate synthase. Biochemistry (2005) 1.07
Blood-borne amyloid-beta dimer correlates with clinical markers of Alzheimer's disease. J Neurosci (2010) 1.05
Discovery of a novel circular single-stranded DNA virus from porcine faeces. Arch Virol (2012) 1.04
Dihydrodipicolinate synthase (DHDPS) from Escherichia coli displays partial mixed inhibition with respect to its first substrate, pyruvate. Biochimie (2004) 1.03
Effects of PPAR gamma ligands on TGF-beta1-induced epithelial-mesenchymal transition in alveolar epithelial cells. Respir Res (2010) 1.03
Substrate-mediated stabilization of a tetrameric drug target reveals Achilles heel in anthrax. J Biol Chem (2009) 1.03
Inhibiting dihydrodipicolinate synthase across species: towards specificity for pathogens? Bioorg Med Chem Lett (2007) 1.01
Purification, crystallization and preliminary X-ray diffraction studies to near-atomic resolution of dihydrodipicolinate synthase from methicillin-resistant Staphylococcus aureus. Acta Crystallogr Sect F Struct Biol Cryst Commun (2008) 0.99
Tyrosine latching of a regulatory gate affords allosteric control of aromatic amino acid biosynthesis. J Biol Chem (2011) 0.99
Dihydrodipicolinate synthase is not inhibited by its substrate, (S)-aspartate beta-semialdehyde. Biochem J (2004) 0.98
Conserved main-chain peptide distortions: a proposed role for Ile203 in catalysis by dihydrodipicolinate synthase. Protein Sci (2008) 0.97
Oligomers, fact or artefact? SDS-PAGE induces dimerization of β-amyloid in human brain samples. Acta Neuropathol (2013) 0.97
Amyloid fibrils as a nanoscaffold for enzyme immobilization. Biotechnol Prog (2010) 0.96
The preparation of (S)-aspartate semi-aldehyde appropriate for use in biochemical studies. Bioorg Med Chem Lett (2003) 0.95
Crystallization and preliminary X-ray analysis of dihydrodipicolinate synthase from Clostridium botulinum in the presence of its substrate pyruvate. Acta Crystallogr Sect F Struct Biol Cryst Commun (2009) 0.94
Two new irreversible inhibitors of dihydrodipicolinate synthase: diethyl (E,E)-4-oxo-2,5-heptadienedioate and diethyl (E)-4-oxo-2-heptenedioate. Bioorg Med Chem Lett (2005) 0.93
Engineering allosteric control to an unregulated enzyme by transfer of a regulatory domain. Proc Natl Acad Sci U S A (2013) 0.92
Expression, purification, crystallization and preliminary X-ray diffraction analysis of dihydrodipicolinate synthase from Bacillus anthracis in the presence of pyruvate. Acta Crystallogr Sect F Struct Biol Cryst Commun (2009) 0.92
Cloning and characterisation of dihydrodipicolinate synthase from the pathogen Neisseria meningitidis. Biochim Biophys Acta (2009) 0.92
Immobilization of organophosphate hydrolase on an amyloid fibril nanoscaffold: towards bioremediation and chemical detoxification. Biotechnol Prog (2010) 0.92
Crystal, solution and in silico structural studies of dihydrodipicolinate synthase from the common grapevine. PLoS One (2012) 0.91
The enantioselective synthesis of APTO and AETD: polyhydroxylated beta-amino acid constituents of the microsclerodermin cyclic peptides. Org Biomol Chem (2007) 0.91
Dual diaminopimelate biosynthesis pathways in Bacteroides fragilis and Clostridium thermocellum. Biochim Biophys Acta (2011) 0.91
Exploring the dihydrodipicolinate synthase tetramer: how resilient is the dimer-dimer interface? Arch Biochem Biophys (2009) 0.90
Purification, crystallization, small-angle X-ray scattering and preliminary X-ray diffraction analysis of the SH2 domain of the Csk-homologous kinase. Acta Crystallogr Sect F Struct Biol Cryst Commun (2011) 0.90
Solid-phase synthesis of homodimeric peptides: preparation of covalently-linked dimers of amyloid beta peptide. Chem Commun (Camb) (2009) 0.90
The high-resolution structure of dihydrodipicolinate synthase from Escherichia coli bound to its first substrate, pyruvate. Acta Crystallogr Sect F Struct Biol Cryst Commun (2008) 0.89
How essential is the 'essential' active-site lysine in dihydrodipicolinate synthase? Biochimie (2010) 0.89
Irreversible inhibition of dihydrodipicolinate synthase by 4-oxo-heptenedioic acid analogues. Bioorg Med Chem (2008) 0.88
Dimerization of bacterial diaminopimelate epimerase is essential for catalysis. J Biol Chem (2013) 0.88
The relationship between oligomeric state and protein function. Adv Exp Med Biol (2012) 0.87
Bovine β-lactoglobulin is dimeric under imitative physiological conditions: dissociation equilibrium and rate constants over the pH range of 2.5-7.5. Biophys J (2012) 0.86
The impact of processing on the nutritional quality of food proteins. J AOAC Int (2005) 0.86
Specificity versus catalytic potency: The role of threonine 44 in Escherichia coli dihydrodipicolinate synthase mediated catalysis. Biochimie (2009) 0.86
A tetrameric structure is not essential for activity in dihydrodipicolinate synthase (DHDPS) from Mycobacterium tuberculosis. Arch Biochem Biophys (2011) 0.86
Characterization of dihydrodipicolinate reductase from Thermotoga maritima reveals evolution of substrate binding kinetics. J Biochem (2008) 0.86
Formation of amyloid-like fibrils by ovalbumin and related proteins under conditions relevant to food processing. J Agric Food Chem (2007) 0.85
Characterisation of the first enzymes committed to lysine biosynthesis in Arabidopsis thaliana. PLoS One (2012) 0.84
Mutating the tight-dimer interface of dihydrodipicolinate synthase disrupts the enzyme quaternary structure: toward a monomeric enzyme. Biochemistry (2008) 0.84
Crystallization and preliminary X-ray diffraction analysis of diaminopimelate epimerase from Escherichia coli. Acta Crystallogr Sect F Struct Biol Cryst Commun (2009) 0.83
Heterocyclic inhibitors of dihydrodipicolinate synthase are not competitive. Bioorg Med Chem (2005) 0.83
Cloning, expression and crystallization of dihydrodipicolinate reductase from methicillin-resistant Staphylococcus aureus. Acta Crystallogr Sect F Struct Biol Cryst Commun (2009) 0.82
Characterization of the structure, expression and function of Pinus radiata D. Don arabinogalactan-proteins. Planta (2007) 0.82
Characterization of monomeric dihydrodipicolinate synthase variant reveals the importance of substrate binding in optimizing oligomerization. Biochim Biophys Acta (2011) 0.81
The C-terminal regulatory domain is required for catalysis by Neisseria meningitidis alpha-isopropylmalate synthase. Biochem Biophys Res Commun (2010) 0.81
Biochemical characterization of UDP-N-acetylmuramoyl-L-alanyl-D-glutamate: meso-2,6-diaminopimelate ligase (MurE) from Verrucomicrobium spinosum DSM 4136(T.). PLoS One (2013) 0.81
The role of quaternary structure in (beta/alpha)(8)-barrel proteins: evolutionary happenstance or a higher level of structure-function relationships? Org Biomol Chem (2009) 0.81
Structural, kinetic and computational investigation of Vitis vinifera DHDPS reveals new insight into the mechanism of lysine-mediated allosteric inhibition. Plant Mol Biol (2013) 0.81
Peroxiredoxin is a versatile self-assembling tecton for protein nanotechnology. Biomacromolecules (2014) 0.81
Disruption of quaternary structure in Escherichia coli dihydrodipicolinate synthase (DHDPS) generates a functional monomer that is no longer inhibited by lysine. Arch Biochem Biophys (2010) 0.81
A new robust kinetic assay for DAP epimerase activity. Biochimie (2013) 0.80
The quaternary structure of pyruvate kinase type 1 from Escherichia coli at low nanomolar concentrations. Biochimie (2009) 0.80
New insights into protein crosslinking via the Maillard reaction: structural requirements, the effect on enzyme function, and predicted efficacy of crosslinking inhibitors as anti-ageing therapeutics. Bioorg Med Chem (2003) 0.80
Aromatic residues in the C-terminal helix of human apoC-I mediate phospholipid interactions and particle morphology. J Lipid Res (2008) 0.80
Cloning, expression, purification and crystallization of dihydrodipicolinate synthase from the psychrophile Shewanella benthica. Acta Crystallogr Sect F Struct Biol Cryst Commun (2010) 0.80
NMR studies uncover alternate substrates for dihydrodipicolinate synthase and suggest that dihydrodipicolinate reductase is also a dehydratase. J Med Chem (2010) 0.80
Enhanced molecular chaperone activity of the small heat-shock protein alphaB-cystallin following covalent immobilization onto a solid-phase support. Biopolymers (2011) 0.80