Published in Acta Crystallogr Sect F Struct Biol Cryst Commun on June 28, 2008
KiDoQ: using docking based energy scores to develop ligand based model for predicting antibacterials. BMC Bioinformatics (2010) 0.93
Virtual Screening of potential drug-like inhibitors against Lysine/DAP pathway of Mycobacterium tuberculosis. BMC Bioinformatics (2010) 0.85
Crystallization and preliminary X-ray diffraction analysis of diaminopimelate epimerase from Escherichia coli. Acta Crystallogr Sect F Struct Biol Cryst Commun (2009) 0.83
Cloning, expression and crystallization of dihydrodipicolinate reductase from methicillin-resistant Staphylococcus aureus. Acta Crystallogr Sect F Struct Biol Cryst Commun (2009) 0.82
Cloning, expression, purification, crystallization and preliminary X-ray diffraction studies of N-acetylneuraminate lyase from methicillin-resistant Staphylococcus aureus. Acta Crystallogr Sect F Struct Biol Cryst Commun (2013) 0.80
Cloning, expression, purification and crystallization of dihydrodipicolinate synthase from the psychrophile Shewanella benthica. Acta Crystallogr Sect F Struct Biol Cryst Commun (2010) 0.80
Cloning, expression, purification and crystallization of dihydrodipicolinate synthase from the grapevine Vitis vinifera. Acta Crystallogr Sect F Struct Biol Cryst Commun (2011) 0.79
Crystallization and preliminary X-ray diffraction analysis of L,L-diaminopimelate aminotransferase (DapL) from Chlamydomonas reinhardtii. Acta Crystallogr Sect F Struct Biol Cryst Commun (2010) 0.79
Crystallization and preliminary X-ray diffraction analysis of dihydrodipicolinate synthase 2 from Arabidopsis thaliana. Acta Crystallogr Sect F Struct Biol Cryst Commun (2011) 0.76
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Crystal structure of dihydrodipicolinate synthase (BA3935) from Bacillus anthracis at 1.94 A resolution. Proteins (2006) 1.40
Dihydrodipicolinate synthase from Thermotoga maritima. Biochem J (2006) 1.37
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Escherichia coli dihydrodipicolinate synthase. Identification of the active site and crystallization. Biochem J (1992) 1.28
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Dihydrodipicolinate synthase ofnicotiana sylvestris, a chloroplast-localized enzyme of the lysine pathway. Planta (1990) 0.86
Regulation of lysine and threonine synthesis in carrot cell suspension cultures and whole carrot roots. Planta (1978) 0.84
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The pseudokinase MLKL mediates necroptosis via a molecular switch mechanism. Immunity (2013) 3.15
Siah ubiquitin ligase is structurally related to TRAF and modulates TNF-alpha signaling. Nat Struct Biol (2002) 2.32
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AMPK beta subunit targets metabolic stress sensing to glycogen. Curr Biol (2003) 2.19
Human factor H-related protein 5 has cofactor activity, inhibits C3 convertase activity, binds heparin and C-reactive protein, and associates with lipoprotein. J Immunol (2005) 1.92
Model for growth hormone receptor activation based on subunit rotation within a receptor dimer. Nat Struct Mol Biol (2005) 1.83
The structure of the GM-CSF receptor complex reveals a distinct mode of cytokine receptor activation. Cell (2008) 1.83
Elucidation of the substrate binding site of Siah ubiquitin ligase. Structure (2006) 1.79
Anxiety over GABA(A) receptor structure relieved by AChBP. Trends Biochem Sci (2002) 1.74
Critical role for the second extracellular loop in the binding of both orthosteric and allosteric G protein-coupled receptor ligands. J Biol Chem (2007) 1.70
Inhibition of lysine biosynthesis: an evolving antibiotic strategy. Mol Biosyst (2007) 1.69
The granulocyte-macrophage colony-stimulating factor receptor: linking its structure to cell signaling and its role in disease. Blood (2009) 1.63
Molecular dissection of the interaction between amyloid precursor protein and its neuronal trafficking receptor SorLA/LR11. Biochemistry (2006) 1.63
Insights into the action of the superfamily of cholesterol-dependent cytolysins from studies of intermedilysin. Proc Natl Acad Sci U S A (2005) 1.63
Cytoplasmic ATP-sensing domains regulate gating of skeletal muscle ClC-1 chloride channels. J Biol Chem (2005) 1.62
Food vacuole-associated lipid bodies and heterogeneous lipid environments in the malaria parasite, Plasmodium falciparum. Mol Microbiol (2004) 1.57
Structures of perfringolysin O suggest a pathway for activation of cholesterol-dependent cytolysins. J Mol Biol (2007) 1.54
Structural basis for glycogen recognition by AMP-activated protein kinase. Structure (2005) 1.50
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An activation-specific platelet inhibitor that can be turned on/off by medically used hypothermia. Arterioscler Thromb Vasc Biol (2011) 1.46
Crystal structure and kinetic study of dihydrodipicolinate synthase from Mycobacterium tuberculosis. Biochem J (2008) 1.46
Rowe and Kahn's model of successful aging revisited: positive spirituality--the forgotten factor. Gerontologist (2002) 1.44
Intrasteric control of AMPK via the gamma1 subunit AMP allosteric regulatory site. Protein Sci (2004) 1.41
Oseltamivir resistance and the H274Y neuraminidase mutation in seasonal, pandemic and highly pathogenic influenza viruses. Drugs (2009) 1.41
Antigen ligation triggers a conformational change within the constant domain of the alphabeta T cell receptor. Immunity (2009) 1.40
Structure and evolution of a novel dimeric enzyme from a clinically important bacterial pathogen. J Biol Chem (2008) 1.38
Structure of the Alzheimer's disease amyloid precursor protein copper binding domain. A regulator of neuronal copper homeostasis. J Biol Chem (2003) 1.38
Dihydrodipicolinate synthase from Thermotoga maritima. Biochem J (2006) 1.37
The structural basis for autonomous dimerization of the pre-T-cell antigen receptor. Nature (2010) 1.35
Federated repositories of X-ray diffraction images. Acta Crystallogr D Biol Crystallogr (2008) 1.33
Inhibition of skeletal muscle ClC-1 chloride channels by low intracellular pH and ATP. J Biol Chem (2007) 1.32
A rivet model for channel formation by aerolysin-like pore-forming toxins. EMBO J (2006) 1.28
Molecular determinants of ginkgolide binding in the glycine receptor pore. J Neurochem (2006) 1.28
The crystal structure of myelin oligodendrocyte glycoprotein, a key autoantigen in multiple sclerosis. Proc Natl Acad Sci U S A (2003) 1.24
The 2.1A crystal structure of the far-red fluorescent protein HcRed: inherent conformational flexibility of the chromophore. J Mol Biol (2005) 1.23
From glutathione transferase to pore in a CLIC. Eur Biophys J (2002) 1.23
The identification and structure of the membrane-spanning domain of the Clostridium septicum alpha toxin. J Biol Chem (2004) 1.22
Age-related differences in plasma proteins: how plasma proteins change from neonates to adults. PLoS One (2011) 1.22
The GM-CSF/IL-3/IL-5 cytokine receptor family: from ligand recognition to initiation of signaling. Immunol Rev (2012) 1.20
Amyloid-beta-anti-amyloid-beta complex structure reveals an extended conformation in the immunodominant B-cell epitope. J Mol Biol (2008) 1.17
Structural characterization of respiratory syncytial virus fusion inhibitor escape mutants: homology model of the F protein and a syncytium formation assay. Virology (2003) 1.17
Altered kinetics and benzodiazepine sensitivity of a GABAA receptor subunit mutation [gamma 2(R43Q)] found in human epilepsy. Proc Natl Acad Sci U S A (2002) 1.14
Molecular characterisation of a novel cassava associated circular ssDNA virus. Virus Res (2012) 1.14
Molecular evolution of glutathione S-transferases in the genus Drosophila. Genetics (2007) 1.14
Mapping the intermedilysin-human CD59 receptor interface reveals a deep correspondence with the binding site on CD59 for complement binding proteins C8alpha and C9. J Biol Chem (2011) 1.12
Evolution of quaternary structure in a homotetrameric enzyme. J Mol Biol (2008) 1.12
A family of helminth molecules that modulate innate cell responses via molecular mimicry of host antimicrobial peptides. PLoS Pathog (2011) 1.10
Ribosome-inactivating proteins: current status and biomedical applications. Drug Discov Today (2012) 1.08
Role of arginine 138 in the catalysis and regulation of Escherichia coli dihydrodipicolinate synthase. Biochemistry (2005) 1.07
Solution conformation and heparin-induced dimerization of the full-length extracellular domain of the human amyloid precursor protein. J Mol Biol (2006) 1.07
Properties of GDP-mannose pyrophosphorylase, a critical enzyme and drug target in Leishmania mexicana. J Biol Chem (2004) 1.05
Insights into the structural basis for zinc inhibition of the glycine receptor. J Biol Chem (2003) 1.05
A proposed structural basis for picrotoxinin and picrotin binding in the glycine receptor pore. J Neurochem (2007) 1.04
Conversion of a transmembrane to a water-soluble protein complex by a single point mutation. Nat Struct Biol (2002) 1.04
Discovery of a novel circular single-stranded DNA virus from porcine faeces. Arch Virol (2012) 1.04
Novel Bcl-2 homology-3 domain-like sequences identified from screening randomized peptide libraries for inhibitors of the pro-survival Bcl-2 proteins. J Biol Chem (2009) 1.03
Solution conformation, backbone dynamics and lipid interactions of the intrinsically unstructured malaria surface protein MSP2. J Mol Biol (2008) 1.03
Substrate-mediated stabilization of a tetrameric drug target reveals Achilles heel in anthrax. J Biol Chem (2009) 1.03
Bapineuzumab captures the N-terminus of the Alzheimer's disease amyloid-beta peptide in a helical conformation. Sci Rep (2013) 1.02
Molecular basis of cytokine receptor activation. IUBMB Life (2010) 1.01
The purification, crystallization and preliminary X-ray diffraction analysis of dihydrodipicolinate synthase from Clostridium botulinum. Acta Crystallogr Sect F Struct Biol Cryst Commun (2008) 1.01
Structure of the Janus protein human CLIC2. J Mol Biol (2007) 1.01
Inhibiting dihydrodipicolinate synthase across species: towards specificity for pathogens? Bioorg Med Chem Lett (2007) 1.01
Synergistic allostery, a sophisticated regulatory network for the control of aromatic amino acid biosynthesis in Mycobacterium tuberculosis. J Biol Chem (2010) 1.00
The trans-Golgi network GRIP-domain proteins form alpha-helical homodimers. Biochem J (2005) 1.00
A [2 x 2] nickel(ii) grid and a copper(ii) square result from differing binding modes of a pyrazine-based diamide ligand. Dalton Trans (2006) 0.99
Tyrosine latching of a regulatory gate affords allosteric control of aromatic amino acid biosynthesis. J Biol Chem (2011) 0.99
Direct involvement of the TEN domain at the active site of human telomerase. Nucleic Acids Res (2010) 0.98
Bicarbonate-mediated stimulation of RegA, the global virulence regulator from Citrobacter rodentium. J Mol Biol (2009) 0.97
Monomer-monomer interactions propagate structural transitions necessary for pore formation by the cholesterol-dependent cytolysins. J Biol Chem (2012) 0.97
Conserved main-chain peptide distortions: a proposed role for Ile203 in catalysis by dihydrodipicolinate synthase. Protein Sci (2008) 0.97
A partially structured region of a largely unstructured protein, Plasmodium falciparum merozoite surface protein 2 (MSP2), forms amyloid-like fibrils. J Pept Sci (2007) 0.96
Dimerization of plant defensin NaD1 enhances its antifungal activity. J Biol Chem (2012) 0.96
Substrate ambiguity and crystal structure of Pyrococcus furiosus 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase: an ancestral 3-deoxyald-2-ulosonate-phosphate synthase? Biochemistry (2005) 0.96
Hsp90 increases LIM kinase activity by promoting its homo-dimerization. FASEB J (2006) 0.96
Nitrosylation of human glutathione transferase P1-1 with dinitrosyl diglutathionyl iron complex in vitro and in vivo. J Biol Chem (2005) 0.96
GSTB1-1 from Proteus mirabilis: a snapshot of an enzyme in the evolutionary pathway from a redox enzyme to a conjugating enzyme. J Biol Chem (2002) 0.95
TRIM16 acts as an E3 ubiquitin ligase and can heterodimerize with other TRIM family members. PLoS One (2012) 0.95
The preparation of (S)-aspartate semi-aldehyde appropriate for use in biochemical studies. Bioorg Med Chem Lett (2003) 0.95
Targeting acute myeloid leukemia by dual inhibition of PI3K signaling and Cdk9-mediated Mcl-1 transcription. Blood (2013) 0.94
Minimal requirements for actin filament disassembly revealed by structural analysis of malaria parasite actin-depolymerizing factor 1. Proc Natl Acad Sci U S A (2011) 0.94
Crystallization and preliminary X-ray analysis of dihydrodipicolinate synthase from Clostridium botulinum in the presence of its substrate pyruvate. Acta Crystallogr Sect F Struct Biol Cryst Commun (2009) 0.94
Contrasting, species-dependent modulation of copper-mediated neurotoxicity by the Alzheimer's disease amyloid precursor protein. J Neurosci (2002) 0.94