Published in Biochem Biophys Res Commun on September 30, 2005
Identification of a chloride ion binding site in Na+/Cl -dependent transporters. Proc Natl Acad Sci U S A (2007) 2.32
Functional properties of multiple isoforms of human divalent metal-ion transporter 1 (DMT1). Biochem J (2007) 1.38
The solute carrier 6 family of transporters. Br J Pharmacol (2012) 1.14
The invertebrate B(0) system transporter, D. melanogaster NAT1, has unique d-amino acid affinity and mediates gut and brain functions. Insect Biochem Mol Biol (2008) 0.94
Branched chain amino acid metabolism profiles in progressive human nonalcoholic fatty liver disease. Amino Acids (2014) 0.93
Is there in vivo evidence for amino acid shuttles carrying ammonia from neurons to astrocytes? Neurochem Res (2012) 0.92
Synergy and specificity of two Na+-aromatic amino acid symporters in the model alimentary canal of mosquito larvae. J Exp Biol (2008) 0.92
In human entrocytes, GLN transport and ASCT2 surface expression induced by short-term EGF are MAPK, PI3K, and Rho-dependent. Dig Dis Sci (2007) 0.91
Deletion of v7-3 (SLC6A15) transporter allows assessment of its roles in synaptosomal proline uptake, leucine uptake and behaviors. Brain Res (2007) 0.90
Teleost fish models in membrane transport research: the PEPT1(SLC15A1) H+-oligopeptide transporter as a case study. J Physiol (2013) 0.87
SNAT2 amino acid transporter is regulated by amino acids of the SLC6 gamma-aminobutyric acid transporter subfamily in neocortical neurons and may play no role in delivering glutamine for glutamatergic transmission. J Biol Chem (2009) 0.87
Synaptic Vesicle Protein NTT4/XT1 (SLC6A17) Catalyzes Na+-coupled Neutral Amino Acid Transport. J Biol Chem (2009) 0.86
Proposed cycles for functional glutamate trafficking in synaptic neurotransmission. Neurochem Int (2007) 0.84
Characterization of the transporterB0AT3 (Slc6a17) in the rodent central nervous system. BMC Neurosci (2013) 0.83
Functional expression of two system A glutamine transporter isoforms in rat auditory brainstem neurons. Neuroscience (2009) 0.82
Involvement of the neutral amino acid transporter SLC6A15 and leucine in obesity-related phenotypes. PLoS One (2013) 0.80
B(0)AT2 (SLC6A15) is localized to neurons and astrocytes, and is involved in mediating the effect of leucine in the brain. PLoS One (2013) 0.80
Mechanism and putative structure of B(0)-like neutral amino acid transporters. J Membr Biol (2007) 0.79
An SLC6 transporter of the novel B(0,)- system aids in absorption and detection of nutrient amino acids in Caenorhabditis elegans. J Exp Biol (2013) 0.77
Protein cold adaptation strategy via a unique seven-amino acid domain in the icefish (Chionodraco hamatus) PEPT1 transporter. Proc Natl Acad Sci U S A (2013) 0.76
Intestinal B(0)AT1 (SLC6A19) and PEPT1 (SLC15A1) mRNA levels in European sea bass (Dicentrarchus labrax) reared in fresh water and fed fish and plant protein sources. J Nutr Sci (2015) 0.76
The D-amino acid transport by the invertebrate SLC6 transporters KAAT1 and CAATCH1 from Manduca sexta. Physiol Rep (2016) 0.75
K-Ras Activation Induces Differential Sensitivity to Sulfur Amino Acid Limitation and Deprivation and to Oxidative and Anti-Oxidative Stress in Mouse Fibroblasts. PLoS One (2016) 0.75
Di- and tripeptide transport in vertebrates: the contribution of teleost fish models. J Comp Physiol B (2016) 0.75
The ABCs of solute carriers: physiological, pathological and therapeutic implications of human membrane transport proteinsIntroduction. Pflugers Arch (2003) 3.76
Mutations in the tight-junction gene claudin 19 (CLDN19) are associated with renal magnesium wasting, renal failure, and severe ocular involvement. Am J Hum Genet (2006) 2.96
The glutamate/neutral amino acid transporter family SLC1: molecular, physiological and pharmacological aspects. Pflugers Arch (2003) 1.75
Marked disturbance of calcium homeostasis in mice with targeted disruption of the Trpv6 calcium channel gene. J Bone Miner Res (2007) 1.56
The calcium-sensing receptor is required for normal calcium homeostasis independent of parathyroid hormone. J Clin Invest (2003) 1.53
Divalent metal-ion transporter DMT1 mediates both H+ -coupled Fe2+ transport and uncoupled fluxes. Pflugers Arch (2005) 1.46
Functional properties of multiple isoforms of human divalent metal-ion transporter 1 (DMT1). Biochem J (2007) 1.38
Calcium transporter 1 and epithelial calcium channel messenger ribonucleic acid are differentially regulated by 1,25 dihydroxyvitamin D3 in the intestine and kidney of mice. Endocrinology (2003) 1.37
Active intestinal calcium transport in the absence of transient receptor potential vanilloid type 6 and calbindin-D9k. Endocrinology (2008) 1.36
The glutamate and neutral amino acid transporter family: physiological and pharmacological implications. Eur J Pharmacol (2003) 1.33
Proton-coupled oligopeptide transporter family SLC15: physiological, pharmacological and pathological implications. Mol Aspects Med (2013) 1.33
Zip14 is a complex broad-scope metal-ion transporter whose functional properties support roles in the cellular uptake of zinc and nontransferrin-bound iron. Am J Physiol Cell Physiol (2011) 1.32
Calcium-selective ion channel, CaT1, is apically localized in gastrointestinal tract epithelia and is aberrantly expressed in human malignancies. Lab Invest (2002) 1.30
ZIP8 is an iron and zinc transporter whose cell-surface expression is up-regulated by cellular iron loading. J Biol Chem (2012) 1.29
Substrate profile and metal-ion selectivity of human divalent metal-ion transporter-1. J Biol Chem (2012) 1.24
Characterization of a stem cell population in lung cancer A549 cells. Biochem Biophys Res Commun (2008) 1.22
Sodium-dependent ascorbic acid transporter family SLC23. Pflugers Arch (2003) 1.20
WNK4 enhances TRPV5-mediated calcium transport: potential role in hypercalciuria of familial hyperkalemic hypertension caused by gene mutation of WNK4. Am J Physiol Renal Physiol (2006) 1.20
Functional properties and cellular distribution of the system A glutamine transporter SNAT1 support specialized roles in central neurons. J Biol Chem (2003) 1.17
CaT1 knock-down strategies fail to affect CRAC channels in mucosal-type mast cells. J Physiol (2004) 1.14
The SLC14 gene family of urea transporters. Pflugers Arch (2003) 1.12
The role of TRPV6 in breast carcinogenesis. Mol Cancer Ther (2008) 1.10
New view at C. Nat Med (2002) 1.09
Identification of mammalian proline transporter SIT1 (SLC6A20) with characteristics of classical system imino. J Biol Chem (2005) 1.09
SLC11 family of H+-coupled metal-ion transporters NRAMP1 and DMT1. Pflugers Arch (2003) 1.06
The SLC1 high-affinity glutamate and neutral amino acid transporter family. Mol Aspects Med (2013) 1.05
Physiologic implications of metal-ion transport by ZIP14 and ZIP8. Biometals (2012) 1.04
Epithelial Ca2+ entry channels: transcellular Ca2+ transport and beyond. J Physiol (2003) 1.02
Down-regulation of intestinal apical calcium entry channel TRPV6 by ubiquitin E3 ligase Nedd4-2. J Biol Chem (2010) 1.00
Disease-causing mutations in KLHL3 impair its effect on WNK4 degradation. FEBS Lett (2013) 0.97
Mammalian iron transporters: families SLC11 and SLC40. Mol Aspects Med (2013) 0.96
Distribution of the glutamate transporters GLT-1 (SLC1A2) and GLAST (SLC1A3) in peripheral organs. Anat Embryol (Berl) (2006) 0.96
H(+)-coupled divalent metal-ion transporter-1: functional properties, physiological roles and therapeutics. Curr Top Membr (2012) 0.96
WNK3 positively regulates epithelial calcium channels TRPV5 and TRPV6 via a kinase-dependent pathway. Am J Physiol Renal Physiol (2008) 0.95
The sodium-dependent ascorbic acid transporter family SLC23. Mol Aspects Med (2013) 0.94
The urea transporter family (SLC14): physiological, pathological and structural aspects. Mol Aspects Med (2013) 0.94
Effect of middle cerebral artery occlusion on mRNA expression for the sodium-coupled vitamin C transporter SVCT2 in rat brain. J Neurochem (2003) 0.94
Kidney function: gateway to a long life? Nature (2002) 0.93
Calcium channel TRPV6 is involved in murine maternal-fetal calcium transport. J Bone Miner Res (2008) 0.93
Intestinal expression of genes involved in iron absorption in humans. Am J Physiol Gastrointest Liver Physiol (2002) 0.93
Disease-causing mutations in the acidic motif of WNK4 impair the sensitivity of WNK4 kinase to calcium ions. Biochem Biophys Res Commun (2012) 0.92
Mechanisms and regulation of epithelial Ca2+ absorption in health and disease. Annu Rev Physiol (2008) 0.92
Iron transport: emerging roles in health and disease. Biochem Cell Biol (2002) 0.92
Regeneration of pancreatic non-β endocrine cells in adult mice following a single diabetes-inducing dose of streptozotocin. PLoS One (2012) 0.92
Gain-of-function haplotype in the epithelial calcium channel TRPV6 is a risk factor for renal calcium stone formation. Hum Mol Genet (2008) 0.91
WNK4 regulates the secretory pathway via which TRPV5 is targeted to the plasma membrane. Biochem Biophys Res Commun (2008) 0.89
Tamoxifen inhibits TRPV6 activity via estrogen receptor-independent pathways in TRPV6-expressing MCF-7 breast cancer cells. Mol Cancer Res (2009) 0.89
Interaction of calcium with the human divalent metal-ion transporter-1. Biochem Biophys Res Commun (2010) 0.88
Inhibition of the human epithelial calcium channel TRPV6 by 2-aminoethoxydiphenyl borate (2-APB). Cell Calcium (2012) 0.88
Calcium-channel blockers do not affect iron transport mediated by divalent metal-ion transporter-1. Blood (2010) 0.87
SARS-CoV proteins decrease levels and activity of human ENaC via activation of distinct PKC isoforms. Am J Physiol Lung Cell Mol Physiol (2008) 0.87
8-pCPT-cGMP stimulates alphabetagamma-ENaC activity in oocytes as an external ligand requiring specific nucleotide moieties. Am J Physiol Renal Physiol (2009) 0.87
Apical entry channels in calcium-transporting epithelia. News Physiol Sci (2003) 0.87
SNAT2 amino acid transporter is regulated by amino acids of the SLC6 gamma-aminobutyric acid transporter subfamily in neocortical neurons and may play no role in delivering glutamine for glutamatergic transmission. J Biol Chem (2009) 0.87
Expression and regulation of epithelial Na+ channels by nucleotides in pleural mesothelial cells. Am J Respir Cell Mol Biol (2008) 0.86
1,25-Dihydroxyvitamin D and 25-hydroxyvitamin D--mediated regulation of TRPV6 (a putative epithelial calcium channel) mRNA expression in Caco-2 cells. Eur J Nutr (2005) 0.86
Tissue-engineered neomucosa: morphology, enterocyte dynamics, and SGLT1 expression topography. Transplantation (2003) 0.86
Functional properties of human ferroportin, a cellular iron exporter reactive also with cobalt and zinc. Am J Physiol Cell Physiol (2013) 0.86
Functional and physiological role of vitamin C transporters. Curr Top Membr (2012) 0.85
The A563T variation of the renal epithelial calcium channel TRPV5 among African Americans enhances calcium influx. Am J Physiol Renal Physiol (2009) 0.84
Membrane tension modulates the effects of apical cholesterol on the renal epithelial sodium channel. J Membr Biol (2007) 0.84
Nutrient transport in the mammary gland: calcium, trace minerals and water soluble vitamins. J Mammary Gland Biol Neoplasia (2014) 0.84
A family of calcium-permeable channels in the kidney: distinct roles in renal calcium handling. Curr Opin Nephrol Hypertens (2002) 0.83
Frog oocytes to unveil the structure and supramolecular organization of human transport proteins. PLoS One (2011) 0.83
Transport model of the human Na+-coupled L-ascorbic acid (vitamin C) transporter SVCT1. Am J Physiol Cell Physiol (2007) 0.83
Heavy metal cations permeate the TRPV6 epithelial cation channel. Cell Calcium (2010) 0.82
Gene transfer of active Akt1 by an infectivity-enhanced adenovirus impacts β-cell survival and proliferation differentially in vitro and in vivo. Islets (2012) 0.82
Disease-causing R1185C mutation of WNK4 disrupts a regulatory mechanism involving calmodulin binding and SGK1 phosphorylation sites. Am J Physiol Renal Physiol (2012) 0.82
Human TRPV5 and TRPV6: key players in cadmium and zinc toxicity. Cell Calcium (2013) 0.81
Suppression of intestinal calcium entry channel TRPV6 by OCRL, a lipid phosphatase associated with Lowe syndrome and Dent disease. Am J Physiol Cell Physiol (2012) 0.81
Synthesis, maturation, and trafficking of human Na+-dicarboxylate cotransporter NaDC1 requires the chaperone activity of cyclophilin B. J Biol Chem (2011) 0.81
Sequence- or position-specific mutations in the carboxyl-terminal FL motif of the kidney sodium bicarbonate cotransporter (NBC1) disrupt its basolateral targeting and alpha-helical structure. J Membr Biol (2009) 0.80
Investigation of the inhibitory effects of the benzodiazepine derivative, 5-BDBD on P2X4 purinergic receptors by two complementary methods. Cell Physiol Biochem (2013) 0.79
Solute carriers (SLCs) in cancer. Mol Aspects Med (2013) 0.79
TRPV5: a Ca(2+) channel for the fine-tuning of Ca(2+) reabsorption. Handb Exp Pharmacol (2014) 0.78
Concerted actions of NHERF2 and WNK4 in regulating TRPV5. Biochem Biophys Res Commun (2010) 0.77
Chemical inhibitors of the calcium entry channel TRPV6. Pharm Res (2010) 0.77
K+ amino acid transporter KAAT1 mutant Y147F has increased transport activity and altered substrate selectivity. J Exp Biol (2003) 0.76
LiZIP3 is a cellular zinc transporter that mediates the tightly regulated import of zinc in Leishmania infantum parasites. Mol Microbiol (2015) 0.76
Design, synthesis and pharmacological characterization of analogs of 2-aminoethyl diphenylborinate (2-APB), a known store-operated calcium channel blocker, for inhibition of TRPV6-mediated calcium transport. Bioorg Med Chem (2013) 0.75
Channels and transporters. Mini-symposium of the Division of Medicinal Chemistry (DMC) of the Swiss Chemical Society (SCS) at the Department of Chemistry, University of Basel, May 27, 2010. Chimia (Aarau) (2010) 0.75