Published in Mol Aspects Med on March 19, 2013
The Concise Guide to PHARMACOLOGY 2013/14: transporters. Br J Pharmacol (2013) 2.07
Vitamin C revisited. Crit Care (2014) 1.01
Uptake of ascorbic acid by pancreatic acinar cells is negatively impacted by chronic alcohol exposure. Am J Physiol Cell Physiol (2016) 0.83
Functional identification of the hypoxanthine/guanine transporters YjcD and YgfQ and the adenine transporters PurP and YicO of Escherichia coli K-12. J Biol Chem (2013) 0.82
[(11)C]Ascorbic and [(11)C]dehydroascorbic acid, an endogenous redox pair for sensing reactive oxygen species using positron emission tomography. Chem Commun (Camb) (2016) 0.78
Expression, purification and low-resolution structure of human vitamin C transporter SVCT1 (SLC23A1). PLoS One (2013) 0.78
The nexus of vitamin homeostasis and DNA synthesis and modification in mammalian brain. Mol Brain (2014) 0.77
Vitamin C Transporters, Recycling and the Bystander Effect in the Nervous System: SVCT2 versus Gluts. J Stem Cell Res Ther (2014) 0.77
Molecular expression and functional activity of vitamin C specific transport system (SVCT2) in human breast cancer cells. Int J Pharm (2014) 0.77
The crucial role of vitamin C and its transporter (SVCT2) in bone marrow stromal cell autophagy and apoptosis. Stem Cell Res (2015) 0.76
Pharmacological doses of daily ascorbate protect tumors from radiation damage after a single dose of radiation in an intracranial mouse glioma model. Front Oncol (2014) 0.75
Unknown components of the plastidial permeome. Front Plant Sci (2014) 0.75
Identification of vitamin C transporters in the human airways: a cross-sectional in vivo study. BMJ Open (2015) 0.75
Ascorbic acid intake and oxalate synthesis. Urolithiasis (2016) 0.75
Vitamin C Transporters in Cancer: Current Understanding and Gaps in Knowledge. Front Oncol (2017) 0.75
Antineutrophil cytoplasmic autoantibodies specific for myeloperoxidase cause glomerulonephritis and vasculitis in mice. J Clin Invest (2002) 5.42
Targeted inactivation of hepatic Abca1 causes profound hypoalphalipoproteinemia and kidney hypercatabolism of apoA-I. J Clin Invest (2005) 3.25
Mutations in the tight-junction gene claudin 19 (CLDN19) are associated with renal magnesium wasting, renal failure, and severe ocular involvement. Am J Hum Genet (2006) 2.96
Increased cellular free cholesterol in macrophage-specific Abca1 knock-out mice enhances pro-inflammatory response of macrophages. J Biol Chem (2008) 2.87
Dietary cholesterol, rather than liver steatosis, leads to hepatic inflammation in hyperlipidemic mouse models of nonalcoholic steatohepatitis. Hepatology (2008) 2.73
Recipes for creating animal models of diabetic cardiovascular disease. Circ Res (2007) 2.34
Targeted deletion of the ileal bile acid transporter eliminates enterohepatic cycling of bile acids in mice. J Biol Chem (2003) 2.26
Tamm-Horsfall protein knockout mice are more prone to urinary tract infection: rapid communication. Kidney Int (2004) 2.17
Molecular phenotyping for analyzing subtle genetic effects in mice: application to an angiotensinogen gene titration. Proc Natl Acad Sci U S A (2002) 2.08
Harmful effects of increased LDLR expression in mice with human APOE*4 but not APOE*3. Arterioscler Thromb Vasc Biol (2003) 2.00
The role of natriuretic peptides in cardioprotection. Cardiovasc Res (2005) 2.00
The role of neutrophils in the induction of glomerulonephritis by anti-myeloperoxidase antibodies. Am J Pathol (2005) 1.97
Hypertension and abnormal fat distribution but not insulin resistance in mice with P465L PPARgamma. J Clin Invest (2004) 1.91
Human vascular smooth muscle cells express a urate transporter. J Am Soc Nephrol (2006) 1.83
Mitochondrial glycerol-3-phosphate acyltransferase-deficient mice have reduced weight and liver triacylglycerol content and altered glycerolipid fatty acid composition. Mol Cell Biol (2002) 1.77
The glutamate/neutral amino acid transporter family SLC1: molecular, physiological and pharmacological aspects. Pflugers Arch (2003) 1.75
Molecular physiology of urate transport. Physiology (Bethesda) (2005) 1.69
Vitamin C is dispensable for oxygen sensing in vivo. Blood (2011) 1.68
Vulnerable atherosclerotic plaque morphology in apolipoprotein E-deficient mice unable to make ascorbic Acid. Circulation (2002) 1.66
CCR5 deficiency is not protective in the early stages of atherogenesis in apoE knockout mice. Atherosclerosis (2003) 1.63
Marked disturbance of calcium homeostasis in mice with targeted disruption of the Trpv6 calcium channel gene. J Bone Miner Res (2007) 1.56
Interference with PPARgamma signaling causes cerebral vascular dysfunction, hypertrophy, and remodeling. Hypertension (2008) 1.55
The calcium-sensing receptor is required for normal calcium homeostasis independent of parathyroid hormone. J Clin Invest (2003) 1.53
Human organic anion transporter 4 is a renal apical organic anion/dicarboxylate exchanger in the proximal tubules. J Pharmacol Sci (2004) 1.52
Genes contributing to prion pathogenesis. J Gen Virol (2008) 1.51
Endogenous production of lipoic acid is essential for mouse development. Mol Cell Biol (2005) 1.49
Tissue inhibitor of metalloproteinase-3 deficiency inhibits blood pressure elevation and myocardial microvascular remodeling induced by chronic administration of Nomega-nitro-L-arginine methyl ester in mice. Hypertens Res (2007) 1.47
Divalent metal-ion transporter DMT1 mediates both H+ -coupled Fe2+ transport and uncoupled fluxes. Pflugers Arch (2005) 1.46
Molecular physiology of renal organic anion transporters. Am J Physiol Renal Physiol (2006) 1.44
The multivalent PDZ domain-containing protein PDZK1 regulates transport activity of renal urate-anion exchanger URAT1 via its C terminus. J Biol Chem (2004) 1.40
Early diet-induced non-alcoholic steatohepatitis in APOE2 knock-in mice and its prevention by fibrates. J Hepatol (2005) 1.40
Senescence-associated phenotypes in Akita diabetic mice are enhanced by absence of bradykinin B2 receptors. J Clin Invest (2006) 1.38
Functional properties of multiple isoforms of human divalent metal-ion transporter 1 (DMT1). Biochem J (2007) 1.38
Calcium transporter 1 and epithelial calcium channel messenger ribonucleic acid are differentially regulated by 1,25 dihydroxyvitamin D3 in the intestine and kidney of mice. Endocrinology (2003) 1.37
The glutamate and neutral amino acid transporter family: physiological and pharmacological implications. Eur J Pharmacol (2003) 1.33
Proton-coupled oligopeptide transporter family SLC15: physiological, pharmacological and pathological implications. Mol Aspects Med (2013) 1.33
The ABCs of membrane transporters in health and disease (SLC series): introduction. Mol Aspects Med (2013) 1.32
Human apoE4-targeted replacement mice display synaptic deficits in the absence of neuropathology. Neurobiol Dis (2005) 1.32
Minireview: estrogen and mouse models of atherosclerosis. Endocrinology (2002) 1.31
Calcium-selective ion channel, CaT1, is apically localized in gastrointestinal tract epithelia and is aberrantly expressed in human malignancies. Lab Invest (2002) 1.30
Ligand-activated peroxisome proliferator-activated receptor-gamma protects against ischemic cerebral infarction and neuronal apoptosis by 14-3-3 epsilon upregulation. Circulation (2009) 1.30
A mouse model of sitosterolemia: absence of Abcg8/sterolin-2 results in failure to secrete biliary cholesterol. BMC Med (2004) 1.28
Contributions from self-renewal and trafficking to the uterine NK cell population of early pregnancy. J Immunol (2002) 1.26
Apolipoprotein E knock-out and knock-in mice: atherosclerosis, metabolic syndrome, and beyond. J Lipid Res (2008) 1.26
Neurotoxicity from innate immune response is greatest with targeted replacement of E4 allele of apolipoprotein E gene and is mediated by microglial p38MAPK. FASEB J (2006) 1.24
Dominant-negative loss of PPARgamma function enhances smooth muscle cell proliferation, migration, and vascular remodeling. Arterioscler Thromb Vasc Biol (2009) 1.23
Characterization of a stem cell population in lung cancer A549 cells. Biochem Biophys Res Commun (2008) 1.22
Disruption of LDL but not VLDL clearance in autosomal recessive hypercholesterolemia. J Clin Invest (2007) 1.22
RNA repair restores hemoglobin expression in IVS2-654 thalassemic mice. Proc Natl Acad Sci U S A (2009) 1.21
Sodium-dependent ascorbic acid transporter family SLC23. Pflugers Arch (2003) 1.20
Mutational and functional analysis of SLC4A4 in a patient with proximal renal tubular acidosis. Pflugers Arch (2004) 1.19
Functional properties and cellular distribution of the system A glutamine transporter SNAT1 support specialized roles in central neurons. J Biol Chem (2003) 1.17
CIB1 is essential for mouse spermatogenesis. Mol Cell Biol (2006) 1.17
Critical role of myeloperoxidase and nicotinamide adenine dinucleotide phosphate-oxidase in high-burden systemic infection of mice with Candida albicans. J Infect Dis (2002) 1.16
A roadmap for the development of alternative (non-animal) methods for systemic toxicity testing - t4 report*. ALTEX (2012) 1.15
CaT1 knock-down strategies fail to affect CRAC channels in mucosal-type mast cells. J Physiol (2004) 1.14
Apolipoprotein E isoforms and apolipoprotein AI protect from amyloid precursor protein carboxy terminal fragment-associated cytotoxicity. J Neurochem (2004) 1.14
Apolipoprotein E-specific innate immune response in astrocytes from targeted replacement mice. J Neuroinflammation (2006) 1.14
Transplantation of monocyte CC-chemokine receptor 2-deficient bone marrow into ApoE3-Leiden mice inhibits atherogenesis. Arterioscler Thromb Vasc Biol (2003) 1.13
The SLC14 gene family of urea transporters. Pflugers Arch (2003) 1.12
Quantitative effects of common genetic variations in the 3'UTR of the human LDL-receptor gene and their associations with plasma lipid levels in the Atherosclerosis Risk in Communities study. Hum Genet (2007) 1.12
Targeted deletion of hepatocyte ABCA1 leads to very low density lipoprotein triglyceride overproduction and low density lipoprotein hypercatabolism. J Biol Chem (2010) 1.11
Aortic constriction exacerbates atherosclerosis and induces cardiac dysfunction in mice lacking apolipoprotein E. Arterioscler Thromb Vasc Biol (2002) 1.11
Shc coordinates signals from intercellular junctions and integrins to regulate flow-induced inflammation. J Cell Biol (2008) 1.11
Loss of TIMP3 enhances interstitial nephritis and fibrosis. J Am Soc Nephrol (2009) 1.10
A modest decrease in endothelial NOS in mice comparable to that associated with human NOS3 variants exacerbates diabetic nephropathy. Proc Natl Acad Sci U S A (2011) 1.10
The role of TRPV6 in breast carcinogenesis. Mol Cancer Ther (2008) 1.10
Adipose tissue ATP binding cassette transporter A1 contributes to high-density lipoprotein biogenesis in vivo. Circulation (2011) 1.09
New view at C. Nat Med (2002) 1.09
Identification of mammalian proline transporter SIT1 (SLC6A20) with characteristics of classical system imino. J Biol Chem (2005) 1.09
Aortic arch curvature and atherosclerosis have overlapping quantitative trait loci in a cross between 129S6/SvEvTac and C57BL/6J apolipoprotein E-null mice. Circ Res (2010) 1.09
Characterization of a branched-chain amino-acid transporter SBAT1 (SLC6A15) that is expressed in human brain. Biochem Biophys Res Commun (2005) 1.08
SCP-2/SCP-x gene ablation alters lipid raft domains in primary cultured mouse hepatocytes. J Lipid Res (2007) 1.06
Genetic variation at the LDL receptor and HMG-CoA reductase gene loci, lipid levels, statin response, and cardiovascular disease incidence in PROSPER. Atherosclerosis (2008) 1.06
Npr1-regulated gene pathways contributing to cardiac hypertrophy and fibrosis. J Mol Endocrinol (2007) 1.06
Protein tyrosine phosphatase PRL-3 in malignant cells and endothelial cells: expression and function. Mol Cancer Ther (2006) 1.06
SLC11 family of H+-coupled metal-ion transporters NRAMP1 and DMT1. Pflugers Arch (2003) 1.06
The SLC1 high-affinity glutamate and neutral amino acid transporter family. Mol Aspects Med (2013) 1.05
Effect of SCP-x gene ablation on branched-chain fatty acid metabolism. Am J Physiol Gastrointest Liver Physiol (2006) 1.05
eNOS deficiency acts through endothelin to aggravate sFlt-1-induced pre-eclampsia-like phenotype. J Am Soc Nephrol (2012) 1.05
Bioinformatic analysis of gene sets regulated by ligand-activated and dominant-negative peroxisome proliferator-activated receptor gamma in mouse aorta. Arterioscler Thromb Vasc Biol (2009) 1.05
An exon 10 deletion in the mouse ferrochelatase gene has a dominant-negative effect and causes mild protoporphyria. Blood (2002) 1.05
Dendritic cell-based multi-epitope immunotherapy of hormone-refractory prostate carcinoma. Cancer Immunol Immunother (2006) 1.04
alpha-Lipoic acid prevents the increase in atherosclerosis induced by diabetes in apolipoprotein E-deficient mice fed high-fat/low-cholesterol diet. Diabetes (2006) 1.03
Deficiency of myeloperoxidase increases infarct volume and nitrotyrosine formation in mouse brain. J Cereb Blood Flow Metab (2002) 1.03
Tissue-specific regulation of ACE/ACE2 and AT1/AT2 receptor gene expression by oestrogen in apolipoprotein E/oestrogen receptor-alpha knock-out mice. Exp Physiol (2008) 1.03
Epithelial Ca2+ entry channels: transcellular Ca2+ transport and beyond. J Physiol (2003) 1.02
Functional characterization of rat organic anion transporter 5 (Slc22a19) at the apical membrane of renal proximal tubules. J Pharmacol Exp Ther (2005) 1.02
A new paradigm for the aging Asian face. Aesthetic Plast Surg (2003) 1.02
Modulation of water efflux through functional interaction between TRPV4 and TMEM16A/anoctamin 1. FASEB J (2014) 1.01
Noninvasive body contouring by focused ultrasound: safety and efficacy of the Contour I device in a multicenter, controlled, clinical study. Plast Reconstr Surg (2007) 1.01
Altering the expression in mice of genes by modifying their 3' regions. Dev Cell (2004) 1.00
Reference values and factors associated with renal resistive index in a family-based population study. Hypertension (2013) 1.00
Role of CYP27A in cholesterol and bile acid metabolism. J Lipid Res (2004) 0.99