Published in FEBS Lett on October 05, 2005
The role of neutral lipid nanospheres in Plasmodium falciparum haem crystallization. Biochem J (2007) 2.27
Protein complex directs hemoglobin-to-hemozoin formation in Plasmodium falciparum. Proc Natl Acad Sci U S A (2013) 1.21
Crystallization of synthetic haemozoin (beta-haematin) nucleated at the surface of lipid particles. Dalton Trans (2009) 1.17
Interference with hemozoin formation represents an important mechanism of schistosomicidal action of antimalarial quinoline methanols. PLoS Negl Trop Dis (2009) 1.06
Malaria pigment crystals as magnetic micro-rotors: key for high-sensitivity diagnosis. Sci Rep (2013) 1.06
Schistosomiasis--a century searching for chemotherapeutic drugs. Parasitol Res (2006) 1.03
Hemozoin: oil versus water. Parasitol Int (2007) 1.00
In vitro activities of trioxaquines against Schistosoma mansoni. Antimicrob Agents Chemother (2009) 0.99
Direct tests of enzymatic heme degradation by the malaria parasite Plasmodium falciparum. J Biol Chem (2012) 0.93
Neutral lipids associated with haemozoin mediate efficient and rapid β-haematin formation at physiological pH, temperature and ionic composition. Malar J (2012) 0.93
Alpha-glucosidase promotes hemozoin formation in a blood-sucking bug: an evolutionary history. PLoS One (2009) 0.90
Schistosoma mansoni hemozoin modulates alternative activation of macrophages via specific suppression of Retnla expression and secretion. Infect Immun (2012) 0.88
Serum lipids and lipoproteins in malaria--a systematic review and meta-analysis. Malar J (2013) 0.88
Schistosome feeding and regurgitation. PLoS Pathog (2014) 0.87
On the mechanisms involved in biological heme crystallization. J Bioenerg Biomembr (2011) 0.87
Peroxisome proliferator-activated receptor (PPAR): balance for survival in parasitic infections. J Biomed Biotechnol (2010) 0.84
Trioxaquine PA1259 alkylates heme in the blood-feeding parasite Schistosoma mansoni. Antimicrob Agents Chemother (2011) 0.84
Identification of hydroxyeicosatetraenoic acid components of schistosomal hemozoin. Biochem Biophys Res Commun (2007) 0.83
Synthetic Hemozoin (β-Hematin) Crystals Nucleate at the Surface of Neutral Lipid Droplets that Control Their Sizes. Cryst Growth Des (2013) 0.82
Phospholipid membrane-mediated hemozoin formation: the effects of physical properties and evidence of membrane surrounding hemozoin. PLoS One (2013) 0.82
Plasmodium falciparum: nitric oxide modulates heme speciation in isolated food vacuoles. Exp Parasitol (2010) 0.82
Increase on the initial soluble heme levels in acidic conditions is an important mechanism for spontaneous heme crystallization in vitro. PLoS One (2010) 0.82
Antischistosomal activity of trioxaquines: in vivo efficacy and mechanism of action on Schistosoma mansoni. PLoS Negl Trop Dis (2012) 0.80
Unsaturated glycerophospholipids mediate heme crystallization: biological implications for hemozoin formation in the kissing bug Rhodnius prolixus. PLoS One (2014) 0.77
Across intra-mammalian stages of the liver f luke Fasciola hepatica: a proteomic study. Sci Rep (2016) 0.76
Hemozoin from Schistosoma japonicum does not affect murine myeloid dendritic cell function. Parasitol Res (2010) 0.76
Growth of Large Hematin Crystals in Biomimetic Solutions. Cryst Growth Des (2014) 0.76
Superparamagnetic Properties of Hemozoin. Sci Rep (2016) 0.75
Characterization and optimization of the haemozoin-like crystal (HLC) assay to determine Hz inhibiting effects of anti-malarial compounds. Malar J (2015) 0.75
Comparison of the in vitro Effects of One-day Exposure to Amodiaquine and Praziquantel on Schistosoma mansoni Adult Worm Pairs. Trop Med Health (2014) 0.75
Characterization of heme as activator of Toll-like receptor 4. J Biol Chem (2007) 2.38
Malarial hemozoin activates the NLRP3 inflammasome through Lyn and Syk kinases. PLoS Pathog (2009) 2.07
Adaptations against heme toxicity in blood-feeding arthropods. Insect Biochem Mol Biol (2006) 2.03
Blood meal-derived heme decreases ROS levels in the midgut of Aedes aegypti and allows proliferation of intestinal microbiota. PLoS Pathog (2011) 1.57
Neutrophil activation by heme: implications for inflammatory processes. Blood (2002) 1.49
Structure and functions of the human amyloid precursor protein: the whole is more than the sum of its parts. Prog Neurobiol (2007) 1.37
Targeting the neurotoxic species in Alzheimer's disease: inhibitors of Abeta oligomerization. FASEB J (2004) 1.35
Identification of the Aedes aegypti peritrophic matrix protein AeIMUCI as a heme-binding protein. Biochemistry (2006) 1.32
Cu-catalyzed cross-dehydrogenative coupling: a versatile strategy for C-C bond formations via the oxidative activation of sp(3) C-H bonds. Proc Natl Acad Sci U S A (2006) 1.30
Lupeol long-chain fatty acid esters with antimalarial activity from Holarrhena floribunda. J Nat Prod (2006) 1.29
Aedes aegypti peritrophic matrix and its interaction with heme during blood digestion. Insect Biochem Mol Biol (2002) 1.25
Amyloid-beta binds to the extracellular cysteine-rich domain of Frizzled and inhibits Wnt/beta-catenin signaling. J Biol Chem (2008) 1.20
Synthetic Plasmodium-like hemozoin activates the immune response: a morphology - function study. PLoS One (2009) 1.10
Inhibition of heme aggregation by chloroquine reduces Schistosoma mansoni infection. J Infect Dis (2004) 1.08
Solution conformation and heparin-induced dimerization of the full-length extracellular domain of the human amyloid precursor protein. J Mol Biol (2006) 1.07
Human apolipoprotein A-I binds amyloid-beta and prevents Abeta-induced neurotoxicity. Int J Biochem Cell Biol (2008) 1.07
A new intracellular pathway of haem detoxification in the midgut of the cattle tick Boophilus microplus: aggregation inside a specialized organelle, the hemosome. J Exp Biol (2003) 1.07
Interference with hemozoin formation represents an important mechanism of schistosomicidal action of antimalarial quinoline methanols. PLoS Negl Trop Dis (2009) 1.06
A new approach to assess function after sciatic nerve lesion in the mouse - adaptation of the sciatic static index. J Neurosci Methods (2007) 1.05
Closed conformation of the active site loop of rabbit muscle triosephosphate isomerase in the absence of substrate: evidence of conformational heterogeneity. J Mol Biol (2003) 1.02
Chemistry of the diazeniumdiolates. O- versus N-alkylation of the RNH[N(O)NO](-) ion. J Am Chem Soc (2004) 1.02
Extracellular lipid droplets promote hemozoin crystallization in the gut of the blood fluke Schistosoma mansoni. FEBS Lett (2007) 1.01
A heme-degradation pathway in a blood-sucking insect. Proc Natl Acad Sci U S A (2006) 1.01
Sensitive detection of malaria infection by third harmonic generation imaging. Biophys J (2007) 1.01
Blood-feeding induces reversible functional changes in flight muscle mitochondria of Aedes aegypti mosquito. PLoS One (2009) 0.98
Changes in salivary nitrophorin profile during the life cycle of the blood-sucking bug Rhodnius prolixus. Insect Biochem Mol Biol (2003) 0.98
Amyloid-β triggers the release of neuronal hexokinase 1 from mitochondria. PLoS One (2010) 0.98
Formation of amyloid aggregates from human lysozyme and its disease-associated variants using hydrostatic pressure. FASEB J (2004) 0.97
Soluble oligomers from a non-disease related protein mimic Abeta-induced tau hyperphosphorylation and neurodegeneration. J Neurochem (2007) 0.97
Chemistry of the diazeniumdiolates: Z right harpoon over left harpoon E isomerism. J Am Chem Soc (2005) 0.96
Energy metabolism affects susceptibility of Anopheles gambiae mosquitoes to Plasmodium infection. Insect Biochem Mol Biol (2011) 0.96
Inhibition of choline acetyltransferase as a mechanism for cholinergic dysfunction induced by amyloid-β peptide oligomers. J Biol Chem (2012) 0.96
Trolox selectively enhances arsenic-mediated oxidative stress and apoptosis in APL and other malignant cell lines. Blood (2004) 0.95
Oxidative stress impairs heme detoxification in the midgut of the cattle tick, Rhipicephalus (Boophilus) microplus. Mol Biochem Parasitol (2006) 0.95
An umpolung approach to cis-hyponitrite complexes. Angew Chem Int Ed Engl (2002) 0.91
Autofluorescence of condensed heme aggregates in malaria pigment and its synthetic equivalent hematin anhydride (beta-hematin). J Phys Chem B (2009) 0.90
Heme crystallization in the midgut of triatomine insects. Comp Biochem Physiol C Toxicol Pharmacol (2006) 0.90
Biglutaminyl-biliverdin IX alpha as a heme degradation product in the dengue fever insect-vector Aedes aegypti. Biochemistry (2007) 0.89
Pigment biocrystallization in Plasmodium falciparum. Trends Parasitol (2002) 0.88
Folding intermediates of the prion protein stabilized by hydrostatic pressure and low temperature. J Biol Chem (2003) 0.88
Activation of GABA(A) receptors by taurine and muscimol blocks the neurotoxicity of beta-amyloid in rat hippocampal and cortical neurons. Neuropharmacology (2005) 0.88
From methylene blue to chloroquine: a brief review of the development of an antimalarial therapy. Parasitol Res (2012) 0.87
HeLp, a heme-transporting lipoprotein with an antioxidant role. Insect Biochem Mol Biol (2004) 0.87
Vaccination of bovines with recombinant Boophilus Yolk pro-Cathepsin. Vet Immunol Immunopathol (2006) 0.87
On the physico-chemical and physiological requirements of hemozoin formation promoted by perimicrovillar membranes in Rhodnius prolixus midgut. Insect Biochem Mol Biol (2010) 0.87
On the pro-oxidant effects of haemozoin. FEBS Lett (2002) 0.87
Amyloidogenicity and cytotoxicity of recombinant mature human islet amyloid polypeptide (rhIAPP). J Biol Chem (2004) 0.87
The novel arsenical darinaparsin is transported by cystine importing systems. Mol Pharmacol (2014) 0.86
Beta-amyloid production, aggregation, and clearance as targets for therapy in Alzheimer's disease. Cell Mol Neurobiol (2002) 0.86
Small molecule inhibitors of lysozyme amyloid aggregation. Cell Biochem Biophys (2006) 0.86
Solution studies and structural model of the extracellular domain of the human amyloid precursor protein. Biophys J (2002) 0.86
The antioxidant role of xanthurenic acid in the Aedes aegypti midgut during digestion of a blood meal. PLoS One (2012) 0.86
Mitochondrial reactive oxygen species modulate mosquito susceptibility to Plasmodium infection. PLoS One (2012) 0.86
The role of reactive oxygen species in Anopheles aquasalis response to Plasmodium vivax infection. PLoS One (2013) 0.85
Peptide blockers of the inhibition of neuronal nicotinic acetylcholine receptors by amyloid beta. J Biol Chem (2005) 0.85
Formation of soluble oligomers and amyloid fibrils with physical properties of the scrapie isoform of the prion protein from the C-terminal domain of recombinant murine prion protein mPrP-(121-231). J Biol Chem (2006) 0.85
Trypanocidal and antileishmanial dihydrochelerythrine derivatives from Garcinia lucida. J Nat Prod (2007) 0.85
Heme-oxygenases during erythropoiesis in K562 and human bone marrow cells. PLoS One (2011) 0.84
Neuritogenesis and neuronal differentiation promoted by 2,4-dinitrophenol, a novel anti-amyloidogenic compound. FASEB J (2005) 0.84
Toward understanding the chloroquine action at the molecular level in antimalarial therapy--X-ray absorption studies in acetic acid solution. J Phys Chem B (2011) 0.84
Synthesis of diazeniumdiolates from the reactions of nitric oxide with enolates. J Org Chem (2006) 0.84
Understanding chloroquine action at the molecular level in antimalarial therapy: X-ray absorption studies in dimethyl sulfoxide solution. J Phys Chem B (2010) 0.83
Leishmania amazonensis: characterization of an ecto-phosphatase activity. Exp Parasitol (2006) 0.82
Folding of a de novo designed native-like four-helix bundle protein. J Biol Chem (2002) 0.82
Rhodnius heme-binding protein (RHBP) is a heme source for embryonic development in the blood-sucking bug Rhodnius prolixus (Hemiptera, Reduviidae). Insect Biochem Mol Biol (2002) 0.82
Trypanosoma brucei brucei: effects of ferrous iron and heme on ecto-nucleoside triphosphate diphosphohydrolase activity. Exp Parasitol (2008) 0.82
Heparin-binding sites in granulocyte-macrophage colony-stimulating factor. Localization and regulation by histidine ionization. J Biol Chem (2005) 0.82
Protein folding, misfolding and aggregation: evolving concepts and conformational diseases. Protein Pept Lett (2005) 0.82
Perimicrovillar membranes promote hemozoin formation into Rhodnius prolixus midgut. Insect Biochem Mol Biol (2007) 0.82
Expression profile of rat hippocampal neurons treated with the neuroprotective compound 2,4-dinitrophenol: up-regulation of cAMP signaling genes. Neurotox Res (2009) 0.82
Antioxidant pathways are up-regulated during biological nitrogen fixation to prevent ROS-induced nitrogenase inhibition in Gluconacetobacter diazotrophicus. Arch Microbiol (2010) 0.82
Multi-frequency high-field EPR study of iron centers in malarial pigments. J Am Chem Soc (2006) 0.81
Proteolytic activity of Boophilus microplus Yolk pro-Cathepsin D (BYC) is coincident with cortical acidification during embryogenesis. Insect Biochem Mol Biol (2004) 0.81
Leishmania amazonensis: characterization of an ecto-3'-nucleotidase activity and its possible role in virulence. Exp Parasitol (2011) 0.81
Functional properties of purified vicilins from cowpea (Vigna unguiculata) and pea (Pisum sativum) and cowpea protein isolate. J Agric Food Chem (2003) 0.81
Silencing of maternal heme-binding protein causes embryonic mitochondrial dysfunction and impairs embryogenesis in the blood sucking insect Rhodnius prolixus. J Biol Chem (2013) 0.81
Cyclic AMP enhancers and Abeta oligomerization blockers as potential therapeutic agents in Alzheimer's disease. Curr Alzheimer Res (2007) 0.81
Predissociated dimers and molten globule monomers in the equilibrium unfolding of yeast glutathione reductase. Biophys J (2003) 0.81
An extraovarian aspartic protease accumulated in tick oocytes with vitellin-degradation activity. Comp Biochem Physiol B Biochem Mol Biol (2008) 0.81
Gold- and silver-catalyzed highly regioselective addition of active methylenes to dienes, triene, and cyclic enol ethers. Org Lett (2005) 0.81
Inhibition of yeast glutathione reductase by trehalose: possible implications in yeast survival and recovery from stress. Int J Biochem Cell Biol (2004) 0.81
Design, synthesis, SAR, and biological evaluation of new 4-(phenylamino)thieno[2,3-b]pyridine derivatives. Bioorg Med Chem (2006) 0.80
Wild habitat and related fauna of Panstrongylus lutzi (Reduviidae, Triatominae). J Med Entomol (2003) 0.80
Transcriptome and gene expression profile of ovarian follicle tissue of the triatomine bug Rhodnius prolixus. Insect Biochem Mol Biol (2011) 0.80
The putrescine analogue 1,4-diamino-2-butanone affects polyamine synthesis, transport, ultrastructure and intracellular survival in Leishmania amazonensis. Microbiology (2008) 0.80
Folding and stability of the extracellular domain of the human amyloid precursor protein. J Biol Chem (2003) 0.80
Novel neuroprotective, neuritogenic and anti-amyloidogenic properties of 2,4-dinitrophenol: the gentle face of Janus. IUBMB Life (2006) 0.80
Phagocytosis is inhibited by autophagic induction in murine macrophages. Biochem Biophys Res Commun (2011) 0.80
Leishmanicidal activity of Cecropia pachystachya flavonoids: arginase inhibition and altered mitochondrial DNA arrangement. Phytochemistry (2013) 0.80
BYC, an atypical aspartic endopeptidase from Rhipicephalus (Boophilus) microplus eggs. Comp Biochem Physiol B Biochem Mol Biol (2007) 0.79
In vivo uptake of a haem analogue Zn protoporphyrin IX by the human malaria parasite P. falciparum-infected red blood cells. Cell Biol Int (2010) 0.79
Photoinduced magnetism in core/shell Prussian blue analogue heterostructures of K(j)Ni(k)[Cr(CN)6]l·nH2O with Rb(a)Co(b)[Fe(CN)6]c·mH2O. Inorg Chem (2011) 0.79
In search of the malarial parasite: biographical sketches of the blood stain contributors. Parasitol Res (2011) 0.78