Published in Org Lett on October 27, 2005
Alzheimer's-associated Abeta oligomers show altered structure, immunoreactivity and synaptotoxicity with low doses of oleocanthal. Toxicol Appl Pharmacol (2009) 1.08
Inhibition of tau fibrillization by oleocanthal via reaction with the amino groups of tau. J Neurochem (2009) 1.05
Unusual pungency from extra-virgin olive oil is attributable to restricted spatial expression of the receptor of oleocanthal. J Neurosci (2011) 1.05
Modulation of protein-protein interactions as a therapeutic strategy for the treatment of neurodegenerative tauopathies. Curr Top Med Chem (2011) 0.89
Impact of a functionalized olive oil extract on the uterus and the bone in a model of postmenopausal osteoporosis. Eur J Nutr (2013) 0.83
Synthesis of (+/-)-Oleocanthal via a Tandem Intramolecular Michael Cyclization-HWE Olefination. Tetrahedron Lett (2009) 0.78
Olive Oil-derived Oleocanthal as Potent Inhibitor of Mammalian Target of Rapamycin: Biological Evaluation and Molecular Modeling Studies. Phytother Res (2015) 0.75
(-)-Oleocanthal inhibits growth and metastasis by blocking activation of STAT3 in human hepatocellular carcinoma. Oncotarget (2016) 0.75
The molecular basis of individual differences in phenylthiocarbamide and propylthiouracil bitterness perception. Curr Biol (2005) 3.41
Food intake, water intake, and drinking spout side preference of 28 mouse strains. Behav Genet (2002) 3.26
Phytochemistry: ibuprofen-like activity in extra-virgin olive oil. Nature (2005) 2.90
T2R38 taste receptor polymorphisms underlie susceptibility to upper respiratory infection. J Clin Invest (2012) 2.66
Taste receptor genes. Annu Rev Nutr (2007) 2.29
Major taste loss in carnivorous mammals. Proc Natl Acad Sci U S A (2012) 1.81
The timing and duration of a sensitive period in human flavor learning: a randomized trial. Am J Clin Nutr (2011) 1.59
Sodium in the food supply: challenges and opportunities. Nutr Rev (2013) 1.56
Pseudogenization of a sweet-receptor gene accounts for cats' indifference toward sugar. PLoS Genet (2005) 1.49
Voluntary consumption of NaCl, KCl, CaCl2, and NH4Cl solutions by 28 mouse strains. Behav Genet (2002) 1.44
Allelic variation of the Tas1r3 taste receptor gene selectively affects behavioral and neural taste responses to sweeteners in the F2 hybrids between C57BL/6ByJ and 129P3/J mice. J Neurosci (2004) 1.43
Optimizing oral medications for children. Clin Ther (2008) 1.42
Flavor experiences during formula feeding are related to preferences during childhood. Early Hum Dev (2002) 1.40
Olfactory fingerprints for major histocompatibility complex-determined body odors II: relationship among odor maps, genetics, odor composition, and behavior. J Neurosci (2002) 1.39
The perception of quinine taste intensity is associated with common genetic variants in a bitter receptor cluster on chromosome 12. Hum Mol Genet (2010) 1.36
Evaluation of the Monell forced-choice, paired-comparison tracking procedure for determining sweet taste preferences across the lifespan. Chem Senses (2011) 1.35
Individual differences in AMY1 gene copy number, salivary α-amylase levels, and the perception of oral starch. PLoS One (2010) 1.34
Flavor programming during infancy. Pediatrics (2004) 1.34
Early milk feeding influences taste acceptance and liking during infancy. Am J Clin Nutr (2009) 1.33
Variability in a taste-receptor gene determines whether we taste toxins in food. Curr Biol (2006) 1.32
Urinary volatile compounds as biomarkers for lung cancer: a proof of principle study using odor signatures in mouse models of lung cancer. PLoS One (2010) 1.31
Allelic variation of the Tas1r3 taste receptor gene selectively affects taste responses to sweeteners: evidence from 129.B6-Tas1r3 congenic mice. Physiol Genomics (2007) 1.28
Heritability and genetic covariation of sensitivity to PROP, SOA, quinine HCl, and caffeine. Chem Senses (2006) 1.24
Probenecid inhibits the human bitter taste receptor TAS2R16 and suppresses bitter perception of salicin. PLoS One (2011) 1.20
A TAS1R receptor-based explanation of sweet 'water-taste'. Nature (2006) 1.20
Gender-specific induction of enhanced sensitivity to odors. Nat Neurosci (2002) 1.19
The development of salty taste acceptance is related to dietary experience in human infants: a prospective study. Am J Clin Nutr (2012) 1.19
Identification of major histocompatibility complex-regulated body odorants by statistical analysis of a comparative gas chromatography/mass spectrometry experiment. Anal Chem (2005) 1.15
Obese women have lower monosodium glutamate taste sensitivity and prefer higher concentrations than do normal-weight women. Obesity (Silver Spring) (2010) 1.12
Perceptual variation in umami taste and polymorphisms in TAS1R taste receptor genes. Am J Clin Nutr (2009) 1.11
Drosophila melanogaster prefers compounds perceived sweet by humans. Chem Senses (2008) 1.11
Gustation assessment using the NIH Toolbox. Neurology (2013) 1.10
Infant regulation of intake: the effect of free glutamate content in infant formulas. Am J Clin Nutr (2012) 1.09
Major histocompatibility complex-regulated odortypes: peptide-free urinary volatile signals. Physiol Behav (2008) 1.08
High endogenous salivary amylase activity is associated with improved glycemic homeostasis following starch ingestion in adults. J Nutr (2012) 1.08
Voluntary ethanol consumption by mice: genome-wide analysis of quantitative trait loci and their interactions in a C57BL/6ByJ x 129P3/J F2 intercross. Genome Res (2002) 1.07
Understanding the origin of flavor preferences. Chem Senses (2005) 1.06
Evolution of functionally diverse alleles associated with PTC bitter taste sensitivity in Africa. Mol Biol Evol (2011) 1.05
Unusual pungency from extra-virgin olive oil is attributable to restricted spatial expression of the receptor of oleocanthal. J Neurosci (2011) 1.05
Genetic basis for MHC-dependent mate choice. Adv Genet (2007) 1.03
Individual odortypes: interaction of MHC and background genes. Immunogenetics (2006) 1.03
Twin study of the heritability of recognition thresholds for sour and salty taste. Chem Senses (2007) 1.03
Prevalence and related risk behaviors of HIV, syphilis, and anal HPV infection among men who have sex with men from Beijing, China. AIDS Behav (2013) 0.99
Genetically-based olfactory signatures persist despite dietary variation. PLoS One (2008) 0.99
Sensory characterization of the irritant properties of oleocanthal, a natural anti-inflammatory agent in extra virgin olive oils. Chem Senses (2009) 0.99
Modification of bitter taste in children. Dev Psychobiol (2003) 0.99
Amiloride-sensitive NaCl taste responses are associated with genetic variation of ENaC alpha-subunit in mice. Am J Physiol Regul Integr Comp Physiol (2007) 0.98
Analyses of sweet receptor gene (Tas1r2) and preference for sweet stimuli in species of Carnivora. J Hered (2009) 0.98
Gustatory neural responses to umami taste stimuli in C57BL/6ByJ and 129P3/J mice. Chem Senses (2004) 0.98
Differential growth patterns among healthy infants fed protein hydrolysate or cow-milk formulas. Pediatrics (2010) 0.98
Effects of repeated exposure and health-related information on hedonic evaluation and acceptance of a bitter beverage. Appetite (2003) 0.97
Cross-adaptation and bitterness inhibition of L-tryptophan, L-phenylalanine and urea: further support for shared peripheral physiology. Chem Senses (2002) 0.96
Genetic, physical, and comparative map of the subtelomeric region of mouse Chromosome 4. Mamm Genome (2002) 0.96
The scent of age. Proc Biol Sci (2003) 0.95
Presence of mouse mammary tumor virus specifically alters the body odor of mice. Proc Natl Acad Sci U S A (2002) 0.94
No relationship between sequence variation in protein coding regions of the Tas1r3 gene and saccharin preference in rats. Chem Senses (2005) 0.94
Amino acid and carbohydrate preferences in C57BL/6ByJ and 129P3/J mice. Physiol Behav (2007) 0.94
Differential binding between volatile ligands and major urinary proteins due to genetic variation in mice. Physiol Behav (2012) 0.93
Analysis of volatile organic compounds released from human lung cancer cells and from the urine of tumor-bearing mice. Cancer Cell Int (2012) 0.92
Vegetable acceptance by infants: effects of formula flavors. Early Hum Dev (2006) 0.92
Glutamate taste and appetite in laboratory mice: physiologic and genetic analyses. Am J Clin Nutr (2009) 0.92
Sweet taste and menthol increase cough reflex thresholds. Pulm Pharmacol Ther (2012) 0.92
Individual differences in sour and salt sensitivity: detection and quality recognition thresholds for citric acid and sodium chloride. Chem Senses (2013) 0.92
Cats lack a sweet taste receptor. J Nutr (2006) 0.91
Modifying the bitterness of selected oral pharmaceuticals with cation and anion series of salts. Pharm Res (2002) 0.91
Bitter taste induces nausea. Curr Biol (2011) 0.90
In search of the chemical basis for MHC odourtypes. Proc Biol Sci (2010) 0.90
Origin and differential selection of allelic variation at TAS2R16 associated with salicin bitter taste sensitivity in Africa. Mol Biol Evol (2013) 0.90
Syntheses of (-)-oleocanthal, a natural NSAID found in extra virgin olive oil, the (-)-deacetoxy-oleuropein aglycone, and related analogues. J Org Chem (2007) 0.89
Is glycine "sweet" to mice? Mouse strain differences in perception of glycine taste. Chem Senses (2006) 0.89
The influence of sodium salts on binary mixtures of bitter-tasting compounds. Chem Senses (2004) 0.88
Oral zinc sulfate solutions inhibit sweet taste perception. Chem Senses (2004) 0.88
Urinary volatile compounds as biomarkers for lung cancer. Biosci Biotechnol Biochem (2012) 0.87
The genetics of bitterness and pungency detection and its impact on phytonutrient evaluation. Ann N Y Acad Sci (2009) 0.87
Mice (Mus musculus) lacking a vomeronasal organ can discriminate MHC-determined odortypes. Horm Behav (2004) 0.86
Immune cells of the human peripheral taste system: dominant dendritic cells and CD4 T cells. Brain Behav Immun (2009) 0.86
A psychophysical investigation of binary bitter-compound interactions. Chem Senses (2003) 0.85
Changes in volatile compounds of mouse urine as it ages: their interactions with water and urinary proteins. Physiol Behav (2013) 0.85
Characterization of human fungiform papillae cells in culture. Chem Senses (2011) 0.85
Myricetin affords protection against peroxynitrite-mediated DNA damage and hydroxyl radical formation. Food Chem Toxicol (2011) 0.85
The liaison of sweet and savory. Chem Senses (2005) 0.85
Complestatin synthetic studies; the effect of the amino acid configuration on peptide backbone conformation in the common western BCD macrocycle. Bioorg Med Chem Lett (2004) 0.85
Sweet taste receptor gene variation and aspartame taste in primates and other species. Chem Senses (2011) 0.85
Bitterness suppression with zinc sulfate and na-cyclamate: a model of combined peripheral and central neural approaches to flavor modification. Pharm Res (2005) 0.85
Genetics of sweet taste preferences. Pure Appl Chem (2002) 0.84
Exact solutions for a type of electron pairing model with spin-orbit interactions and Zeeman coupling. Phys Rev Lett (2011) 0.83
Taste perception of monosodium glutamate and inosine monophosphate by 129P3/J and C57BL/6ByJ mice. Physiol Behav (2009) 0.83
Genetics of sweet taste preferences. Flavour Fragr J (2011) 0.82
Antimicrobial activity of Chinese bayberry extract for the preservation of surimi. J Sci Food Agric (2012) 0.82
Constitutive overexpression of soybean plasma membrane intrinsic protein GmPIP1;6 confers salt tolerance. BMC Plant Biol (2014) 0.81
Butylated hydroxytoluene is a ligand of urinary proteins derived from female mice. Chem Senses (2011) 0.81
Flavor processing: perceptual and cognitive factors in multi-modal integration. Chem Senses (2005) 0.80
Chemosensory recognition of olfactory individuality. Chem Senses (2005) 0.80
Graphene-based solid-phase extraction disk for fast separation and preconcentration of trace polycyclic aromatic hydrocarbons from environmental water samples. J Sep Sci (2013) 0.80
The T cells in peripheral taste tissue of healthy human adults: predominant memory T cells and Th-1 cells. Chem Senses (2010) 0.80