Published in Cell on November 04, 2005
Epstein-Barr virus and virus human protein interaction maps. Proc Natl Acad Sci U S A (2007) 3.50
The SAGA continues: expanding the cellular role of a transcriptional co-activator complex. Oncogene (2007) 2.04
Dynamic regulation of PGC-1alpha localization and turnover implicates mitochondrial adaptation in calorie restriction and the stress response. Aging Cell (2007) 1.87
Dynamic and combinatorial control of gene expression by nuclear retinoic acid receptors (RARs). Nucl Recept Signal (2009) 1.80
The ubiquitin-proteasome system of Saccharomyces cerevisiae. Genetics (2012) 1.73
Distinct modes of regulation of the Uch37 deubiquitinating enzyme in the proteasome and in the Ino80 chromatin-remodeling complex. Mol Cell (2008) 1.71
Ubiquitin and proteasomes in transcription. Annu Rev Biochem (2012) 1.67
Yeast homolog of a cancer-testis antigen defines a new transcription complex. EMBO J (2006) 1.58
Revealing static and dynamic modular architecture of the eukaryotic protein interaction network. Mol Syst Biol (2007) 1.53
Multi-tasking on chromatin with the SAGA coactivator complexes. Mutat Res (2007) 1.50
Diverse chromatin remodeling genes antagonize the Rb-involved SynMuv pathways in C. elegans. PLoS Genet (2006) 1.47
Subcomplexes of PA700, the 19 S regulator of the 26 S proteasome, reveal relative roles of AAA subunits in 26 S proteasome assembly and activation and ATPase activity. J Biol Chem (2009) 1.38
The role of the proteasomal ATPases and activator monoubiquitylation in regulating Gal4 binding to promoters. Genes Dev (2006) 1.32
CCR4/NOT complex associates with the proteasome and regulates histone methylation. Proc Natl Acad Sci U S A (2007) 1.30
SAGA binds TBP via its Spt8 subunit in competition with DNA: implications for TBP recruitment. EMBO J (2006) 1.21
Some assembly required: dedicated chaperones in eukaryotic proteasome biogenesis. Biol Chem (2008) 1.16
FACT and the proteasome promote promoter chromatin disassembly and transcriptional initiation. J Biol Chem (2009) 1.15
The proteolytic function of the Arabidopsis 26S proteasome is required for specifying leaf adaxial identity. Plant Cell (2006) 1.14
No Splicing, no dicing: non-proteolytic roles of the ubiquitin-proteasome system in transcription. J Biol Chem (2009) 1.14
The RNA exosome and proteasome: common principles of degradation control. Nat Rev Mol Cell Biol (2013) 1.12
Organellar proteomics reveals hundreds of novel nuclear proteins in the malaria parasite Plasmodium falciparum. Genome Biol (2012) 1.12
Physical and functional interactions of monoubiquitylated transactivators with the proteasome. J Biol Chem (2008) 1.08
Proteasome activity modulates chromatin modifications and RNA polymerase II phosphorylation to enhance glucocorticoid receptor-mediated transcription. Mol Cell Biol (2007) 1.04
Proteasome subunits relocalize during human cytomegalovirus infection, and proteasome activity is necessary for efficient viral gene transcription. J Virol (2009) 1.03
Roles for APIS and the 20S proteasome in adenovirus E1A-dependent transcription. EMBO J (2006) 1.01
Regulation of acetylation at the major histocompatibility complex class II proximal promoter by the 19S proteasomal ATPase Sug1. Mol Cell Biol (2008) 1.00
Identification of Rkr1, a nuclear RING domain protein with functional connections to chromatin modification in Saccharomyces cerevisiae. Mol Cell Biol (2007) 0.98
Distinct regulatory mechanisms of eukaryotic transcriptional activation by SAGA and TFIID. Biochim Biophys Acta (2010) 0.97
Neuron enriched nuclear proteome isolated from human brain. J Proteome Res (2013) 0.97
Activation domain-dependent monoubiquitylation of Gal4 protein is essential for promoter binding in vivo. J Biol Chem (2008) 0.96
The proteasome: not just degrading anymore. Cell (2005) 0.96
Intermediate filament transcription in astrocytes is repressed by proteasome inhibition. FASEB J (2009) 0.95
Structure characterization of the 26S proteasome. Biochim Biophys Acta (2010) 0.95
Cks1, Cdk1, and the 19S proteasome collaborate to regulate gene induction-dependent nucleosome eviction in yeast. Mol Cell Biol (2010) 0.95
The 19S proteasome subcomplex promotes the targeting of NuA4 HAT to the promoters of ribosomal protein genes to facilitate the recruitment of TFIID for transcriptional initiation in vivo. Nucleic Acids Res (2011) 0.94
The 19 s proteasome subcomplex establishes a specific protein interaction network at the promoter for stimulated transcriptional initiation in vivo. J Biol Chem (2009) 0.93
Misfolding of proteins with a polyglutamine expansion is facilitated by proteasomal chaperones. J Biol Chem (2008) 0.91
A SAGA-independent function of SPT3 mediates transcriptional deregulation in a mutant of the Ccr4-not complex in Saccharomyces cerevisiae. Genetics (2007) 0.91
Promoter context determines the role of proteasome in ligand-dependent occupancy of retinoic acid responsive elements. Epigenetics (2011) 0.90
Regulation of gene expression by the ubiquitin-proteasome system. Semin Cell Dev Biol (2012) 0.89
The Snf1 kinase and proteasome-associated Rad23 regulate UV-responsive gene expression. EMBO J (2009) 0.88
Tat-binding protein-1 (TBP-1), an ATPase of 19S regulatory particles of the 26S proteasome, enhances androgen receptor function in cooperation with TBP-1-interacting protein/Hop2. Endocrinology (2009) 0.88
PRDM1 is required for mantle cell lymphoma response to bortezomib. Mol Cancer Res (2010) 0.86
New suppressors of THO mutations identify Thp3 (Ypr045c)-Csn12 as a protein complex involved in transcription elongation. Mol Cell Biol (2010) 0.85
Intersection of nuclear receptors and the proteasome on the epigenetic landscape. Environ Mol Mutagen (2008) 0.85
Paradoxical instability-activity relationship defines a novel regulatory pathway for retinoblastoma proteins. Mol Biol Cell (2010) 0.85
SUG-1 plays proteolytic and non-proteolytic roles in the control of retinoic acid target genes via its interaction with SRC-3. J Biol Chem (2009) 0.82
A ramble through the cell: how can we clear such a complicated trail? CBE Life Sci Educ (2006) 0.82
Distinct amino acids of histone H3 control secondary metabolism in Aspergillus nidulans. Appl Environ Microbiol (2013) 0.81
The 19S proteasome is directly involved in the regulation of heterochromatin spreading in fission yeast. J Biol Chem (2017) 0.80
The hydrophobic patch of ubiquitin is required to protect transactivator-promoter complexes from destabilization by the proteasomal ATPases. Nucleic Acids Res (2009) 0.80
Emerging roles of the 26S proteasome in nuclear hormone receptor-regulated transcription. Biochim Biophys Acta (2010) 0.79
Invadolysin, a conserved lipid-droplet-associated metalloproteinase, is required for mitochondrial function in Drosophila. J Cell Sci (2013) 0.79
The 26S proteasome and initiation of gene transcription. Biomolecules (2014) 0.79
The 26S proteasome drives trinucleotide repeat expansions. Nucleic Acids Res (2013) 0.78
The Rad23 ubiquitin receptor, the proteasome and functional specificity in transcriptional control. Transcription (2012) 0.78
Distant positioning of proteasomal proteolysis relative to actively transcribed genes. Nucleic Acids Res (2011) 0.78
A global perspective of the genetic basis for carbonyl stress resistance. G3 (Bethesda) (2011) 0.78
Cks1 enhances transcription efficiency at the GAL1 locus by linking the Paf1 complex to the 19S proteasome. Eukaryot Cell (2013) 0.77
The C-terminal residues of Saccharomyces cerevisiae Mec1 are required for its localization, stability, and function. G3 (Bethesda) (2013) 0.77
Cks1 activates transcription by binding to the ubiquitylated proteasome. Mol Cell Biol (2010) 0.76
Role of Sug1, a 19S proteasome ATPase, in the transcription of MHC I and the atypical MHC II molecules, HLA-DM and HLA-DO. Immunol Lett (2012) 0.76
A regulatory mechanism involving TBP-1/Tat-Binding Protein 1 and Akt/PKB in the control of cell proliferation. PLoS One (2011) 0.76
Functions of the proteasome on chromatin. Biomolecules (2014) 0.76
Enzymatic assays for assessing histone deubiquitylation activity. Methods (2011) 0.75
Subgenic Pol II interactomes identify region-specific transcription elongation regulators. Mol Syst Biol (2017) 0.75
Transcriptional Activation of Pericentromeric Satellite Repeats and Disruption of Centromeric Clustering upon Proteasome Inhibition. PLoS One (2016) 0.75
Role of Plc1p in regulation of Mcm1p-dependent genes. FEMS Microbiol Lett (2009) 0.75
Nonproteolytic roles of 19S ATPases in transcription of CIITApIV genes. PLoS One (2014) 0.75
Phosphorylation of the 19S regulatory particle ATPase subunit, Rpt6, modifies susceptibility to proteotoxic stress and protein aggregation. PLoS One (2017) 0.75
Molecular characterization of the Rpt1/p48B ATPase subunit of the Drosophila melanogaster 26S proteasome. Mol Genet Genomics (2007) 0.75
MYC Modulation around the CDK2/p27/SKP2 Axis. Genes (Basel) (2017) 0.75
The role of chromatin during transcription. Cell (2007) 26.48
Histone H3 methylation by Set2 directs deacetylation of coding regions by Rpd3S to suppress spurious intragenic transcription. Cell (2005) 10.68
From silencing to gene expression: real-time analysis in single cells. Cell (2004) 7.73
Function and selectivity of bromodomains in anchoring chromatin-modifying complexes to promoter nucleosomes. Cell (2002) 7.10
Updating and validating the Charlson comorbidity index and score for risk adjustment in hospital discharge abstracts using data from 6 countries. Am J Epidemiol (2011) 5.41
Histone acetyltransferase complexes: one size doesn't fit all. Nat Rev Mol Cell Biol (2007) 5.12
Evasion of the p53 tumour surveillance network by tumour-derived MYC mutants. Nature (2005) 4.97
Acetylation by Tip60 is required for selective histone variant exchange at DNA lesions. Science (2004) 4.97
How the ubiquitin-proteasome system controls transcription. Nat Rev Mol Cell Biol (2003) 4.90
Angiogenesis-independent endothelial protection of liver: role of VEGFR-1. Science (2003) 4.56
Histone ubiquitination: triggering gene activity. Mol Cell (2008) 4.42
Assessing validity of ICD-9-CM and ICD-10 administrative data in recording clinical conditions in a unique dually coded database. Health Serv Res (2008) 4.25
The Set2 histone methyltransferase functions through the phosphorylated carboxyl-terminal domain of RNA polymerase II. J Biol Chem (2003) 4.13
Skp2 regulates Myc protein stability and activity. Mol Cell (2003) 3.85
Global position and recruitment of HATs and HDACs in the yeast genome. Mol Cell (2004) 3.74
Preferential occupancy of histone variant H2AZ at inactive promoters influences local histone modifications and chromatin remodeling. Proc Natl Acad Sci U S A (2005) 3.72
Combined action of PHD and chromo domains directs the Rpd3S HDAC to transcribed chromatin. Science (2007) 3.69
A chemical probe selectively inhibits G9a and GLP methyltransferase activity in cells. Nat Chem Biol (2011) 3.60
Risk of COPD from exposure to biomass smoke: a metaanalysis. Chest (2010) 3.46
Analyzing chromatin remodeling complexes using shotgun proteomics and normalized spectral abundance factors. Methods (2006) 3.37
The diverse functions of histone acetyltransferase complexes. Trends Genet (2003) 3.35
The proteasome: a utility tool for transcription? Curr Opin Genet Dev (2006) 3.29
Respiratory uncoupling lowers blood pressure through a leptin-dependent mechanism in genetically obese mice. Arterioscler Thromb Vasc Biol (2002) 3.01
Acetyl-CoA induces cell growth and proliferation by promoting the acetylation of histones at growth genes. Mol Cell (2011) 2.88
MSL complex is attracted to genes marked by H3K36 trimethylation using a sequence-independent mechanism. Mol Cell (2007) 2.87
Macrophage Wnt7b is critical for kidney repair and regeneration. Proc Natl Acad Sci U S A (2010) 2.87
Scm3 is essential to recruit the histone h3 variant cse4 to centromeres and to maintain a functional kinetochore. Mol Cell (2007) 2.82
Infrequently transcribed long genes depend on the Set2/Rpd3S pathway for accurate transcription. Genes Dev (2007) 2.82
Human origin recognition complex large subunit is degraded by ubiquitin-mediated proteolysis after initiation of DNA replication. Mol Cell (2002) 2.81
RSC exploits histone acetylation to abrogate the nucleosomal block to RNA polymerase II elongation. Mol Cell (2006) 2.77
Signals and combinatorial functions of histone modifications. Annu Rev Biochem (2011) 2.76
The F box protein Dsg1/Mdm30 is a transcriptional coactivator that stimulates Gal4 turnover and cotranscriptional mRNA processing. Cell (2005) 2.75
SIRT2 maintains genome integrity and suppresses tumorigenesis through regulating APC/C activity. Cancer Cell (2011) 2.73
Crosstalk among Histone Modifications. Cell (2008) 2.70
HIV-neutralizing immunoglobulin A and HIV-specific proliferation are independently associated with reduced HIV acquisition in Kenyan sex workers. AIDS (2008) 2.67
Set2 methylation of histone H3 lysine 36 suppresses histone exchange on transcribed genes. Nature (2012) 2.57
Inducible gene expression: diverse regulatory mechanisms. Nat Rev Genet (2010) 2.53
A role for Snf2-related nucleosome-spacing enzymes in genome-wide nucleosome organization. Science (2011) 2.50
Readers of histone modifications. Cell Res (2011) 2.40
Chromatin remodelers Isw1 and Chd1 maintain chromatin structure during transcription by preventing histone exchange. Nat Struct Mol Biol (2012) 2.37
Escape from autologous neutralizing antibodies in acute/early subtype C HIV-1 infection requires multiple pathways. PLoS Pathog (2009) 2.29
Phosphorylated Pol II CTD recruits multiple HDACs, including Rpd3C(S), for methylation-dependent deacetylation of ORF nucleosomes. Mol Cell (2010) 2.26
p31comet blocks Mad2 activation through structural mimicry. Cell (2007) 2.26
Association of EGFR mutation or ALK rearrangement with expression of DNA repair and synthesis genes in never-smoker women with pulmonary adenocarcinoma. Cancer (2012) 2.24
Cse4 is part of an octameric nucleosome in budding yeast. Mol Cell (2009) 2.23
Enhancement of synaptic plasticity through chronically reduced Ca2+ flux during uncorrelated activity. Neuron (2004) 2.21
Proteasomal ATPases link ubiquitylation of histone H2B to methylation of histone H3. Mol Cell (2004) 2.20
An epidemiologic survey of pediatric sepsis in regional hospitals in China. Pediatr Crit Care Med (2014) 2.16
A mammalian chromatin remodeling complex with similarities to the yeast INO80 complex. J Biol Chem (2005) 2.10
Breast cancer metastasis suppressor 1 (BRMS1) forms complexes with retinoblastoma-binding protein 1 (RBP1) and the mSin3 histone deacetylase complex and represses transcription. J Biol Chem (2003) 1.98
The novel SLIK histone acetyltransferase complex functions in the yeast retrograde response pathway. Mol Cell Biol (2002) 1.98
The deubiquitylation activity of Ubp8 is dependent upon Sgf11 and its association with the SAGA complex. Mol Cell Biol (2005) 1.95
Histone H3 lysine 36 dimethylation (H3K36me2) is sufficient to recruit the Rpd3s histone deacetylase complex and to repress spurious transcription. J Biol Chem (2009) 1.94
The mammalian YL1 protein is a shared subunit of the TRRAP/TIP60 histone acetyltransferase and SRCAP complexes. J Biol Chem (2005) 1.93
ATAC is a double histone acetyltransferase complex that stimulates nucleosome sliding. Nat Struct Mol Biol (2008) 1.90
An orally bioavailable chemical probe of the Lysine Methyltransferases EZH2 and EZH1. ACS Chem Biol (2013) 1.89
Role of neuronal energy status in the regulation of adenosine 5'-monophosphate-activated protein kinase, orexigenic neuropeptides expression, and feeding behavior. Endocrinology (2004) 1.87
Molecular recognition by a binary code. J Mol Biol (2005) 1.85
Transcription activator interactions with multiple SWI/SNF subunits. Mol Cell Biol (2002) 1.82
In and out: histone variant exchange in chromatin. Trends Biochem Sci (2005) 1.81
An artificial somatic-autonomic reflex pathway procedure for bladder control in children with spina bifida. J Urol (2005) 1.78
Cyfip1 is a putative invasion suppressor in epithelial cancers. Cell (2009) 1.77
An artificial somatic-central nervous system-autonomic reflex pathway for controllable micturition after spinal cord injury: preliminary results in 15 patients. J Urol (2003) 1.73
Mice expressing a humanized form of VEGF-A may provide insights into the safety and efficacy of anti-VEGF antibodies. Proc Natl Acad Sci U S A (2007) 1.73
Rtr1 is a CTD phosphatase that regulates RNA polymerase II during the transition from serine 5 to serine 2 phosphorylation. Mol Cell (2009) 1.68
Ubiquitin and proteasomes in transcription. Annu Rev Biochem (2012) 1.67
The changing faces of HP1: From heterochromatin formation and gene silencing to euchromatic gene expression: HP1 acts as a positive regulator of transcription. Bioessays (2011) 1.67
Stable incorporation of sequence specific repressors Ash1 and Ume6 into the Rpd3L complex. Biochim Biophys Acta (2005) 1.66
Preparation of nuclear and cytoplasmic extracts from mammalian cells. Curr Protoc Mol Biol (2006) 1.66
The heterochromatin protein 1 (HP1) family: put away a bias toward HP1. Mol Cells (2008) 1.66
Two Drosophila Ada2 homologues function in different multiprotein complexes. Mol Cell Biol (2003) 1.63
Depletion of CD4⁺ T cells abrogates post-peak decline of viremia in SIV-infected rhesus macaques. J Clin Invest (2011) 1.62
Psh1 is an E3 ubiquitin ligase that targets the centromeric histone variant Cse4. Mol Cell (2010) 1.62
Mutants of Mucor hiemalis endo-beta-N-acetylglucosaminidase show enhanced transglycosylation and glycosynthase-like activities. J Biol Chem (2007) 1.62
Host cell factor and an uncharacterized SANT domain protein are stable components of ATAC, a novel dAda2A/dGcn5-containing histone acetyltransferase complex in Drosophila. Mol Cell Biol (2006) 1.60
The HIR corepressor complex binds to nucleosomes generating a distinct protein/DNA complex resistant to remodeling by SWI/SNF. Genes Dev (2005) 1.57
The MSL3 chromodomain directs a key targeting step for dosage compensation of the Drosophila melanogaster X chromosome. Nat Struct Mol Biol (2008) 1.55
SAGA-mediated H2B deubiquitination controls the development of neuronal connectivity in the Drosophila visual system. EMBO J (2008) 1.54
IL-23 promotes CD4+ T cells to produce IL-17 in Vogt-Koyanagi-Harada disease. J Allergy Clin Immunol (2007) 1.54
Phage-displayed antibody libraries of synthetic heavy chain complementarity determining regions. J Mol Biol (2004) 1.53
Sgf29 binds histone H3K4me2/3 and is required for SAGA complex recruitment and histone H3 acetylation. EMBO J (2011) 1.52
Clinical characteristics of Vogt-Koyanagi-Harada syndrome in Chinese patients. Ophthalmology (2006) 1.52
SAS-mediated acetylation of histone H4 Lys 16 is required for H2A.Z incorporation at subtelomeric regions in Saccharomyces cerevisiae. Genes Dev (2006) 1.51
Follow-through after calling a nurse telephone advice line: a population-based study. Fam Pract (2010) 1.50
The B cell response is redundant and highly focused on V1V2 during early subtype C infection in a Zambian seroconverter. J Virol (2010) 1.49
Abnormal anterior cingulum in patients with schizophrenia: a diffusion tensor imaging study. Neuroreport (2003) 1.49