Published in J Biol Chem on November 09, 2005
Deficiency of Dol-P-Man synthase subunit DPM3 bridges the congenital disorders of glycosylation with the dystroglycanopathies. Am J Hum Genet (2009) 1.83
Understanding human glycosylation disorders: biochemistry leads the charge. J Biol Chem (2013) 1.72
Identification of AglE, a second glycosyltransferase involved in N glycosylation of the Haloferax volcanii S-layer glycoprotein. J Bacteriol (2008) 1.41
The o-mannosylation pathway: glycosyltransferases and proteins implicated in congenital muscular dystrophy. J Biol Chem (2013) 1.28
DOLICHOL PHOSPHATE MANNOSE SYNTHASE1 mediates the biogenesis of isoprenyl-linked glycans and influences development, stress response, and ammonium hypersensitivity in Arabidopsis. Plant Cell (2011) 0.90
Congenital disorder of glycosylation due to DPM1 mutations presenting with dystroglycanopathy-type congenital muscular dystrophy. Mol Genet Metab (2013) 0.87
Glycosyltransferase mechanisms: impact of a 5-fluoro substituent in acceptor and donor substrates on catalysis. Biochemistry (2007) 0.86
A thermostable dolichol phosphoryl mannose synthase responsible for glycoconjugate synthesis of the hyperthermophilic archaeon Pyrococcus horikoshii. Extremophiles (2008) 0.80
Genome-Wide Screening of Genes Required for Glycosylphosphatidylinositol Biosynthesis. PLoS One (2015) 0.79
Role of Epithelial-Mesenchyme Transition in Chlamydia Pathogenesis. PLoS One (2015) 0.78
Heritable disorders in the metabolism of the dolichols: A bridge from sterol biosynthesis to molecular glycosylation. Am J Med Genet C Semin Med Genet (2012) 0.75
Angiotensin-converting enzyme is a GPI-anchored protein releasing factor crucial for fertilization. Nat Med (2005) 4.02
Diagnosis and management of paroxysmal nocturnal hemoglobinuria. Blood (2005) 3.71
Identity-by-descent filtering of exome sequence data identifies PIGV mutations in hyperphosphatasia mental retardation syndrome. Nat Genet (2010) 3.60
Direct recognition of the mycobacterial glycolipid, trehalose dimycolate, by C-type lectin Mincle. J Exp Med (2009) 3.19
Region-specific saturation germline mutagenesis in mice using the Sleeping Beauty transposon system. Nat Methods (2005) 2.70
Protein kinase D regulates basolateral membrane protein exit from trans-Golgi network. Nat Cell Biol (2004) 2.59
Hypomorphic promoter mutation in PIGM causes inherited glycosylphosphatidylinositol deficiency. Nat Med (2006) 1.97
Biosynthesis, remodelling and functions of mammalian GPI-anchored proteins: recent progress. J Biochem (2008) 1.94
Genetic variants in C5 and poor response to eculizumab. N Engl J Med (2014) 1.91
Molecular basis of clonal expansion of hematopoiesis in 2 patients with paroxysmal nocturnal hemoglobinuria (PNH). Blood (2006) 1.86
Deficiency of Dol-P-Man synthase subunit DPM3 bridges the congenital disorders of glycosylation with the dystroglycanopathies. Am J Hum Genet (2009) 1.83
Protein kinase D: an intracellular traffic regulator on the move. Trends Cell Biol (2002) 1.81
Clinical course and flow cytometric analysis of paroxysmal nocturnal hemoglobinuria in the United States and Japan. Medicine (Baltimore) (2004) 1.67
Mutations in PIGO, a member of the GPI-anchor-synthesis pathway, cause hyperphosphatasia with mental retardation. Am J Hum Genet (2012) 1.65
A case of paroxysmal nocturnal hemoglobinuria caused by a germline mutation and a somatic mutation in PIGT. Blood (2013) 1.61
GPHR-dependent functions of the Golgi apparatus are essential for the formation of lamellar granules and the skin barrier. J Invest Dermatol (2012) 1.48
Inositol deacylation of glycosylphosphatidylinositol-anchored proteins is mediated by mammalian PGAP1 and yeast Bst1p. J Biol Chem (2004) 1.44
Genome-wide phenotype analysis in ES cells by regulated disruption of Bloom's syndrome gene. Nature (2004) 1.42
PGAP2 is essential for correct processing and stable expression of GPI-anchored proteins. Mol Biol Cell (2006) 1.38
PimE is a polyprenol-phosphate-mannose-dependent mannosyltransferase that transfers the fifth mannose of phosphatidylinositol mannoside in mycobacteria. J Biol Chem (2006) 1.36
GPI-anchor remodeling: potential functions of GPI-anchors in intracellular trafficking and membrane dynamics. Biochim Biophys Acta (2012) 1.34
Fatty acid remodeling of GPI-anchored proteins is required for their raft association. Mol Biol Cell (2007) 1.34
Hypomorphic mutations in PGAP2, encoding a GPI-anchor-remodeling protein, cause autosomal-recessive intellectual disability. Am J Hum Genet (2013) 1.34
GPHR is a novel anion channel critical for acidification and functions of the Golgi apparatus. Nat Cell Biol (2008) 1.33
Requirement of N-glycan on GPI-anchored proteins for efficient binding of aerolysin but not Clostridium septicum alpha-toxin. EMBO J (2002) 1.33
Surface sialic acids taken from the host allow trypanosome survival in tsetse fly vectors. J Exp Med (2004) 1.31
PIG-V involved in transferring the second mannose in glycosylphosphatidylinositol. J Biol Chem (2004) 1.22
Glycosylphosphatidylinositol (GPI) anchor deficiency caused by mutations in PIGW is associated with West syndrome and hyperphosphatasia with mental retardation syndrome. J Med Genet (2013) 1.19
PGAP2 mutations, affecting the GPI-anchor-synthesis pathway, cause hyperphosphatasia with mental retardation syndrome. Am J Hum Genet (2013) 1.17
Targeted therapy for inherited GPI deficiency. N Engl J Med (2007) 1.17
GPI glycan remodeling by PGAP5 regulates transport of GPI-anchored proteins from the ER to the Golgi. Cell (2009) 1.16
Mechanism for release of alkaline phosphatase caused by glycosylphosphatidylinositol deficiency in patients with hyperphosphatasia mental retardation syndrome. J Biol Chem (2012) 1.16
Human PIG-U and yeast Cdc91p are the fifth subunit of GPI transamidase that attaches GPI-anchors to proteins. Mol Biol Cell (2003) 1.12
Structural remodeling, trafficking and functions of glycosylphosphatidylinositol-anchored proteins. Prog Lipid Res (2011) 1.12
Mammalian GPI-anchored proteins require p24 proteins for their efficient transport from the ER to the plasma membrane. Biochem J (2008) 1.09
Structural remodeling of GPI anchors during biosynthesis and after attachment to proteins. FEBS Lett (2009) 1.08
Sorting of GPI-anchored proteins into ER exit sites by p24 proteins is dependent on remodeled GPI. J Cell Biol (2011) 1.06
Integrin-linked kinase associated with integrin activation. Blood (2009) 1.06
Enhanced humoral immune responses against T-independent antigens in Fc alpha/muR-deficient mice. Proc Natl Acad Sci U S A (2009) 1.05
Two subunits of glycosylphosphatidylinositol transamidase, GPI8 and PIG-T, form a functionally important intermolecular disulfide bridge. J Biol Chem (2003) 1.05
Association of dengue virus NS1 protein with lipid rafts. J Gen Virol (2008) 1.04
Prostacyclin-deficient mice develop ischemic renal disorders, including nephrosclerosis and renal infarction. Circulation (2002) 1.02
PIG-W is critical for inositol acylation but not for flipping of glycosylphosphatidylinositol-anchor. Mol Biol Cell (2003) 0.99
Dolichol-phosphate mannose synthase: structure, function and regulation. Biochim Biophys Acta (2008) 0.99
Effects of combined training with breathing resistance and sustained physical exertion to improve endurance capacity and respiratory muscle function in healthy young adults. J Phys Ther Sci (2013) 0.99
A study of upper extremity training for patients with stroke using a virtual environment system. J Phys Ther Sci (2013) 0.98
PGAP1 knock-out mice show otocephaly and male infertility. J Biol Chem (2007) 0.98
GPI transamidase of Trypanosoma brucei has two previously uncharacterized (trypanosomatid transamidase 1 and 2) and three common subunits. Proc Natl Acad Sci U S A (2003) 0.97
The glycan core of GPI-anchored proteins modulates aerolysin binding but is not sufficient: the polypeptide moiety is required for the toxin-receptor interaction. FEBS Lett (2002) 0.94
Acquisition of complement resistance through incorporation of CD55/decay-accelerating factor into viral particles bearing baculovirus GP64. J Virol (2010) 0.93
Erythrocyte surface glycosylphosphatidyl inositol anchored receptor for the malaria parasite. Mol Biochem Parasitol (2005) 0.93
Safety and efficacy of the terminal complement inhibitor eculizumab in Japanese patients with paroxysmal nocturnal hemoglobinuria: the AEGIS clinical trial. Int J Hematol (2011) 0.93
The acidic environment of the Golgi is critical for glycosylation and transport. Methods Enzymol (2010) 0.93
Inositol lipid metabolism in mycobacteria: biosynthesis and regulatory mechanisms. Biochim Biophys Acta (2011) 0.92
Peroxisome dependency of alkyl-containing GPI-anchor biosynthesis in the endoplasmic reticulum. Proc Natl Acad Sci U S A (2009) 0.92
The initial enzyme for glycosylphosphatidylinositol biosynthesis requires PIG-Y, a seventh component. Mol Biol Cell (2005) 0.92
GPI7 is the second partner of PIG-F and involved in modification of glycosylphosphatidylinositol. J Biol Chem (2005) 0.92
CHO glycosylation mutants: GPI anchor. Methods Enzymol (2006) 0.91
Vitamin B6-responsive epilepsy due to inherited GPI deficiency. Neurology (2013) 0.91
Mammalian PIG-X and yeast Pbn1p are the essential components of glycosylphosphatidylinositol-mannosyltransferase I. Mol Biol Cell (2005) 0.90
Structural requirements for the recruitment of Gaa1 into a functional glycosylphosphatidylinositol transamidase complex. J Biol Chem (2002) 0.90
Enhanced response of T lymphocytes from Pgap3 knockout mouse: Insight into roles of fatty acid remodeling of GPI anchored proteins. Biochem Biophys Res Commun (2011) 0.90
Transport of glycosylphosphatidylinositol-anchored proteins from the endoplasmic reticulum. Biochim Biophys Acta (2013) 0.89
PIGN mutations cause congenital anomalies, developmental delay, hypotonia, epilepsy, and progressive cerebellar atrophy. Neurogenetics (2013) 0.89
Molecular genetics of paroxysmal nocturnal hemoglobinuria. Int J Hematol (2003) 0.88
PIGA mutations cause early-onset epileptic encephalopathies and distinctive features. Neurology (2014) 0.88
Controlled expression of branch-forming mannosyltransferase is critical for mycobacterial lipoarabinomannan biosynthesis. J Biol Chem (2010) 0.87
Decreased susceptibility of leukemic cells with PIG-A mutation to natural killer cells in vitro. Blood (2002) 0.86
Golgi-associated GSK3beta regulates the sorting process of post-Golgi membrane trafficking. J Cell Sci (2010) 0.86
Guideline for hereditary angioedema (HAE) 2010 by the Japanese Association for Complement Research - secondary publication. Allergol Int (2012) 0.86
Deregulated expression of HMGA2 is implicated in clonal expansion of PIGA deficient cells in paroxysmal nocturnal haemoglobinuria. Br J Haematol (2011) 0.86