Published in Biochem Biophys Res Commun on December 29, 2011
Transbilayer lipid interactions mediate nanoclustering of lipid-anchored proteins. Cell (2015) 1.78
Mutations in PGAP3 impair GPI-anchor maturation, causing a subtype of hyperphosphatasia with mental retardation. Am J Hum Genet (2014) 1.20
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Defective lipid remodeling of GPI anchors in peroxisomal disorders, Zellweger syndrome, and rhizomelic chondrodysplasia punctata. J Lipid Res (2012) 0.83
Significance of glycosylphosphatidylinositol-anchored protein enrichment in lipid rafts for the control of autoimmunity. J Biol Chem (2013) 0.82
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GPI-anchored protein organization and dynamics at the cell surface. J Lipid Res (2015) 0.77
Angiotensin-converting enzyme is a GPI-anchored protein releasing factor crucial for fertilization. Nat Med (2005) 4.02
Diagnosis and management of paroxysmal nocturnal hemoglobinuria. Blood (2005) 3.71
Identity-by-descent filtering of exome sequence data identifies PIGV mutations in hyperphosphatasia mental retardation syndrome. Nat Genet (2010) 3.60
Direct recognition of the mycobacterial glycolipid, trehalose dimycolate, by C-type lectin Mincle. J Exp Med (2009) 3.19
Region-specific saturation germline mutagenesis in mice using the Sleeping Beauty transposon system. Nat Methods (2005) 2.70
Protein kinase D regulates basolateral membrane protein exit from trans-Golgi network. Nat Cell Biol (2004) 2.59
Heparin-binding EGF-like growth factor and ErbB signaling is essential for heart function. Proc Natl Acad Sci U S A (2003) 2.45
Hypomorphic promoter mutation in PIGM causes inherited glycosylphosphatidylinositol deficiency. Nat Med (2006) 1.97
Biosynthesis, remodelling and functions of mammalian GPI-anchored proteins: recent progress. J Biochem (2008) 1.94
Genetic variants in C5 and poor response to eculizumab. N Engl J Med (2014) 1.91
Epidermal growth factor receptor mutations in small cell lung cancer. Clin Cancer Res (2008) 1.88
Molecular basis of clonal expansion of hematopoiesis in 2 patients with paroxysmal nocturnal hemoglobinuria (PNH). Blood (2006) 1.86
Deficiency of Dol-P-Man synthase subunit DPM3 bridges the congenital disorders of glycosylation with the dystroglycanopathies. Am J Hum Genet (2009) 1.83
Protein kinase D: an intracellular traffic regulator on the move. Trends Cell Biol (2002) 1.81
Clinical course and flow cytometric analysis of paroxysmal nocturnal hemoglobinuria in the United States and Japan. Medicine (Baltimore) (2004) 1.67
Mutations in PIGO, a member of the GPI-anchor-synthesis pathway, cause hyperphosphatasia with mental retardation. Am J Hum Genet (2012) 1.65
An agr-like two-component regulatory system in Lactobacillus plantarum is involved in production of a novel cyclic peptide and regulation of adherence. J Bacteriol (2005) 1.61
A case of paroxysmal nocturnal hemoglobinuria caused by a germline mutation and a somatic mutation in PIGT. Blood (2013) 1.61
Pravastatin induces placental growth factor (PGF) and ameliorates preeclampsia in a mouse model. Proc Natl Acad Sci U S A (2010) 1.56
GPHR-dependent functions of the Golgi apparatus are essential for the formation of lamellar granules and the skin barrier. J Invest Dermatol (2012) 1.48
Inositol deacylation of glycosylphosphatidylinositol-anchored proteins is mediated by mammalian PGAP1 and yeast Bst1p. J Biol Chem (2004) 1.44
Genome-wide phenotype analysis in ES cells by regulated disruption of Bloom's syndrome gene. Nature (2004) 1.42
Heparin-binding EGF-like growth factor is a promising target for ovarian cancer therapy. Cancer Res (2004) 1.41
PGAP2 is essential for correct processing and stable expression of GPI-anchored proteins. Mol Biol Cell (2006) 1.38
PimE is a polyprenol-phosphate-mannose-dependent mannosyltransferase that transfers the fifth mannose of phosphatidylinositol mannoside in mycobacteria. J Biol Chem (2006) 1.36
GPI-anchor remodeling: potential functions of GPI-anchors in intracellular trafficking and membrane dynamics. Biochim Biophys Acta (2012) 1.34
Fatty acid remodeling of GPI-anchored proteins is required for their raft association. Mol Biol Cell (2007) 1.34
Hypomorphic mutations in PGAP2, encoding a GPI-anchor-remodeling protein, cause autosomal-recessive intellectual disability. Am J Hum Genet (2013) 1.34
GPHR is a novel anion channel critical for acidification and functions of the Golgi apparatus. Nat Cell Biol (2008) 1.33
Requirement of N-glycan on GPI-anchored proteins for efficient binding of aerolysin but not Clostridium septicum alpha-toxin. EMBO J (2002) 1.33
PYPAF3, a PYRIN-containing APAF-1-like protein, is a feedback regulator of caspase-1-dependent interleukin-1beta secretion. J Biol Chem (2005) 1.33
Surface sialic acids taken from the host allow trypanosome survival in tsetse fly vectors. J Exp Med (2004) 1.31
PIG-V involved in transferring the second mannose in glycosylphosphatidylinositol. J Biol Chem (2004) 1.22
Glycosylphosphatidylinositol (GPI) anchor deficiency caused by mutations in PIGW is associated with West syndrome and hyperphosphatasia with mental retardation syndrome. J Med Genet (2013) 1.19
PGAP2 mutations, affecting the GPI-anchor-synthesis pathway, cause hyperphosphatasia with mental retardation syndrome. Am J Hum Genet (2013) 1.17
Targeted therapy for inherited GPI deficiency. N Engl J Med (2007) 1.17
GPI glycan remodeling by PGAP5 regulates transport of GPI-anchored proteins from the ER to the Golgi. Cell (2009) 1.16
Mechanism for release of alkaline phosphatase caused by glycosylphosphatidylinositol deficiency in patients with hyperphosphatasia mental retardation syndrome. J Biol Chem (2012) 1.16
Anti-inflammatory activity of PYNOD and its mechanism in humans and mice. J Immunol (2010) 1.15
Lineage-specific cell disruption in living mice by Cre-mediated expression of diphtheria toxin A chain. Biochem Biophys Res Commun (2004) 1.14
Human PIG-U and yeast Cdc91p are the fifth subunit of GPI transamidase that attaches GPI-anchors to proteins. Mol Biol Cell (2003) 1.12
Structural remodeling, trafficking and functions of glycosylphosphatidylinositol-anchored proteins. Prog Lipid Res (2011) 1.12
Mammalian GPI-anchored proteins require p24 proteins for their efficient transport from the ER to the plasma membrane. Biochem J (2008) 1.09
Expanding the repertoire of optogenetically targeted cells with an enhanced gene expression system. Cell Rep (2012) 1.08
Structural remodeling of GPI anchors during biosynthesis and after attachment to proteins. FEBS Lett (2009) 1.08
Sorting of GPI-anchored proteins into ER exit sites by p24 proteins is dependent on remodeled GPI. J Cell Biol (2011) 1.06
Integrin-linked kinase associated with integrin activation. Blood (2009) 1.06
Enhanced humoral immune responses against T-independent antigens in Fc alpha/muR-deficient mice. Proc Natl Acad Sci U S A (2009) 1.05
Two subunits of glycosylphosphatidylinositol transamidase, GPI8 and PIG-T, form a functionally important intermolecular disulfide bridge. J Biol Chem (2003) 1.05
Association of dengue virus NS1 protein with lipid rafts. J Gen Virol (2008) 1.04
Prostacyclin-deficient mice develop ischemic renal disorders, including nephrosclerosis and renal infarction. Circulation (2002) 1.02
Dolichol-phosphate mannose synthase: structure, function and regulation. Biochim Biophys Acta (2008) 0.99
Effects of combined training with breathing resistance and sustained physical exertion to improve endurance capacity and respiratory muscle function in healthy young adults. J Phys Ther Sci (2013) 0.99
PIG-W is critical for inositol acylation but not for flipping of glycosylphosphatidylinositol-anchor. Mol Biol Cell (2003) 0.99
A study of upper extremity training for patients with stroke using a virtual environment system. J Phys Ther Sci (2013) 0.98
PGAP1 knock-out mice show otocephaly and male infertility. J Biol Chem (2007) 0.98
GPI transamidase of Trypanosoma brucei has two previously uncharacterized (trypanosomatid transamidase 1 and 2) and three common subunits. Proc Natl Acad Sci U S A (2003) 0.97
Seminal vesicle protein SVS2 is required for sperm survival in the uterus. Proc Natl Acad Sci U S A (2014) 0.97
Microleakage of composite resin restoration in cavities prepared by Er,Cr:YSGG laser irradiation and etched bur cavities in primary teeth. J Clin Pediatr Dent (2002) 0.96
The glycan core of GPI-anchored proteins modulates aerolysin binding but is not sufficient: the polypeptide moiety is required for the toxin-receptor interaction. FEBS Lett (2002) 0.94
DPM1, the catalytic subunit of dolichol-phosphate mannose synthase, is tethered to and stabilized on the endoplasmic reticulum membrane by DPM3. J Biol Chem (2005) 0.94
Acquisition of complement resistance through incorporation of CD55/decay-accelerating factor into viral particles bearing baculovirus GP64. J Virol (2010) 0.93
The acidic environment of the Golgi is critical for glycosylation and transport. Methods Enzymol (2010) 0.93
Safety and efficacy of the terminal complement inhibitor eculizumab in Japanese patients with paroxysmal nocturnal hemoglobinuria: the AEGIS clinical trial. Int J Hematol (2011) 0.93
Erythrocyte surface glycosylphosphatidyl inositol anchored receptor for the malaria parasite. Mol Biochem Parasitol (2005) 0.93
Inositol lipid metabolism in mycobacteria: biosynthesis and regulatory mechanisms. Biochim Biophys Acta (2011) 0.92
Peroxisome dependency of alkyl-containing GPI-anchor biosynthesis in the endoplasmic reticulum. Proc Natl Acad Sci U S A (2009) 0.92