Published in J Neurosci on November 09, 2005
Dnmt1 and Dnmt3a maintain DNA methylation and regulate synaptic function in adult forebrain neurons. Nat Neurosci (2010) 5.12
Quantitative expression profiling of identified neurons reveals cell-specific constraints on highly variable levels of gene expression. Proc Natl Acad Sci U S A (2007) 2.62
Histone methylation regulates memory formation. J Neurosci (2010) 2.30
The IkappaB kinase regulates chromatin structure during reconsolidation of conditioned fear memories. Neuron (2007) 2.29
Beyond transcription factors: the role of chromatin modifying enzymes in regulating transcription required for memory. Learn Mem (2008) 2.15
The function of activity-regulated genes in the nervous system. Physiol Rev (2009) 1.54
Epigenetic principles and mechanisms underlying nervous system functions in health and disease. Prog Neurobiol (2008) 1.53
Addiction science: Uncovering neurobiological complexity. Neuropharmacology (2013) 1.50
Chronic cocaine-induced H3 acetylation and transcriptional activation of CaMKIIalpha in the nucleus accumbens is critical for motivation for drug reinforcement. Neuropsychopharmacology (2009) 1.46
Maternal separation alters drug intake patterns in adulthood in rats. Biochem Pharmacol (2006) 1.41
Children of addicted women. J Addict Dis (2010) 1.37
Conductance ratios and cellular identity. PLoS Comput Biol (2010) 1.33
Drug-induced epigenetic changes produce drug tolerance. PLoS Biol (2007) 1.18
Hatching the behavioral addiction egg: Reward Deficiency Solution System (RDSS)™ as a function of dopaminergic neurogenetics and brain functional connectivity linking all addictions under a common rubric. J Behav Addict (2014) 1.02
The secret language of destiny: stress imprinting and transgenerational origins of disease. Front Genet (2012) 0.97
The site specific demethylation in the 5'-regulatory area of NMDA receptor 2B subunit gene associated with CIE-induced up-regulation of transcription. PLoS One (2010) 0.97
Genomic features of the human dopamine transporter gene and its potential epigenetic States: implications for phenotypic diversity. PLoS One (2010) 0.96
Epigenetic gene regulation in the adult mammalian brain: multiple roles in memory formation. Neurobiol Learn Mem (2011) 0.93
Genomic and epigenomic responses to chronic stress involve miRNA-mediated programming. PLoS One (2012) 0.93
Events at the transition between cell cycle exit and oligodendrocyte progenitor differentiation: the role of HDAC and YY1. Neuron Glia Biol (2007) 0.91
Epigenetic mechanisms in experience-driven memory formation and behavior. Epigenomics (2011) 0.88
The HDAC Inhibitor Phenylbutyrate Reverses Effects of Neonatal Ventral Hippocampal Lesion in Rats. Front Psychiatry (2011) 0.85
Prenatal stress induces spatial memory deficits and epigenetic changes in the hippocampus indicative of heterochromatin formation and reduced gene expression. Behav Brain Res (2014) 0.83
The inhibition of histone deacetylases reduces the reinstatement of cocaine-seeking behavior in rats. Curr Neuropharmacol (2011) 0.82
Playing inside the genes: Intragenic histone acetylation after membrane depolarization of neural cells opens a path for alternative splicing regulation. Commun Integr Biol (2009) 0.80
Therapeutic targeting of "DARPP-32": a key signaling molecule in the dopiminergic pathway for the treatment of opiate addiction. Int Rev Neurobiol (2009) 0.79
Addiction as a systems failure: focus on adolescence and smoking. J Am Acad Child Adolesc Psychiatry (2011) 0.79
CNS genes implicated in relapse. Subst Abuse (2008) 0.77
Neurogenetic and epigenetic correlates of adolescent predisposition to and risk for addictive behaviors as a function of prefrontal cortex dysregulation. J Child Adolesc Psychopharmacol (2015) 0.76
Refining psychiatric genetics: from 'mouse psychiatry' to understanding complex human disorders. Behav Pharmacol (2008) 0.76
Overexpression of cyclic GMP-dependent protein kinase reduces MeCP2 and HDAC2 expression. Brain Behav (2012) 0.76
Effects of sodium butyrate on methamphetamine-sensitized locomotor activity. Behav Brain Res (2012) 0.76
Epigenetics in mental illness: hope or hype? J Psychiatry Neurosci (2010) 0.76
hElp3 directly modulates the expression of HSP70 gene in HeLa cells via HAT activity. PLoS One (2011) 0.76
Long-term window of ischemic tolerance: An evolutionarily conserved form of metabolic plasticity regulated by epigenetic modifications? J Neurol Neuromedicine (2016) 0.75
Total levels of hippocampal histone acetylation predict normal variability in mouse behavior. PLoS One (2014) 0.75
Epigenetic programming by maternal behavior. Nat Neurosci (2004) 20.92
Neural mechanisms of addiction: the role of reward-related learning and memory. Annu Rev Neurosci (2006) 12.37
Essential role of BDNF in the mesolimbic dopamine pathway in social defeat stress. Science (2006) 9.31
Molecular adaptations underlying susceptibility and resistance to social defeat in brain reward regions. Cell (2007) 8.99
REST and its corepressors mediate plasticity of neuronal gene chromatin throughout neurogenesis. Cell (2005) 8.65
Sustained hippocampal chromatin regulation in a mouse model of depression and antidepressant action. Nat Neurosci (2006) 8.24
The knockout mouse project. Nat Genet (2004) 7.80
Nucleus accumbens D2/3 receptors predict trait impulsivity and cocaine reinforcement. Science (2007) 6.75
A cAMP-response element binding protein-induced microRNA regulates neuronal morphogenesis. Proc Natl Acad Sci U S A (2005) 6.61
The molecular neurobiology of depression. Nature (2008) 6.51
Defining the CREB regulon: a genome-wide analysis of transcription factor regulatory regions. Cell (2004) 6.08
Epigenetic regulation in psychiatric disorders. Nat Rev Neurosci (2007) 6.00
Reciprocal actions of REST and a microRNA promote neuronal identity. Proc Natl Acad Sci U S A (2006) 5.78
A genetic screen for candidate tumor suppressors identifies REST. Cell (2005) 5.61
The many faces of CREB. Trends Neurosci (2005) 5.58
Cell type-specific loss of BDNF signaling mimics optogenetic control of cocaine reward. Science (2010) 5.48
CBP histone acetyltransferase activity is a critical component of memory consolidation. Neuron (2004) 5.40
A biochemical approach to identifying microRNA targets. Proc Natl Acad Sci U S A (2007) 5.16
Chromatin remodeling is a key mechanism underlying cocaine-induced plasticity in striatum. Neuron (2005) 5.09
Histone deacetylase 5 epigenetically controls behavioral adaptations to chronic emotional stimuli. Neuron (2007) 4.96
New approaches to antidepressant drug discovery: beyond monoamines. Nat Rev Neurosci (2006) 4.62
Regulation of gene expression and cocaine reward by CREB and DeltaFosB. Nat Neurosci (2003) 4.60
microRNA modulation of circadian-clock period and entrainment. Neuron (2007) 4.49
Corepressor-dependent silencing of chromosomal regions encoding neuronal genes. Science (2002) 4.19
Early thimerosal exposure and neuropsychological outcomes at 7 to 10 years. N Engl J Med (2007) 4.16
Activity-dependent dendritic arborization mediated by CaM-kinase I activation and enhanced CREB-dependent transcription of Wnt-2. Neuron (2006) 4.10
An activity-regulated microRNA controls dendritic plasticity by down-regulating p250GAP. Proc Natl Acad Sci U S A (2008) 3.98
Essential role of the histone methyltransferase G9a in cocaine-induced plasticity. Science (2010) 3.97
Mania-like behavior induced by disruption of CLOCK. Proc Natl Acad Sci U S A (2007) 3.92
Regulation of corepressor function by nuclear NADH. Science (2002) 3.83
Homeostatic regulation of MeCP2 expression by a CREB-induced microRNA. Nat Neurosci (2007) 3.81
Disruption of dendritic translation of CaMKIIalpha impairs stabilization of synaptic plasticity and memory consolidation. Neuron (2002) 3.78
Psychobiology and molecular genetics of resilience. Nat Rev Neurosci (2009) 3.71
Transcriptional and epigenetic mechanisms of addiction. Nat Rev Neurosci (2011) 3.69
Generation of a synthetic memory trace. Science (2012) 3.55
Localization of a stable neural correlate of associative memory. Science (2007) 3.50
Contrasting roles of basolateral amygdala and orbitofrontal cortex in impulsive choice. J Neurosci (2004) 3.48
Reversal of maternal programming of stress responses in adult offspring through methyl supplementation: altering epigenetic marking later in life. J Neurosci (2005) 3.48
DeltaFosB in brain reward circuits mediates resilience to stress and antidepressant responses. Nat Neurosci (2010) 3.47
Non-cell autonomous influence of MeCP2-deficient glia on neuronal dendritic morphology. Nat Neurosci (2009) 3.42
Dnmt3a regulates emotional behavior and spine plasticity in the nucleus accumbens. Nat Neurosci (2010) 3.41
Essential role of brain-derived neurotrophic factor in adult hippocampal function. Proc Natl Acad Sci U S A (2004) 3.37
CREB activity in the nucleus accumbens shell controls gating of behavioral responses to emotional stimuli. Proc Natl Acad Sci U S A (2002) 3.32
The many faces of REST oversee epigenetic programming of neuronal genes. Curr Opin Neurobiol (2005) 3.25
Decoding the epigenetic language of neuronal plasticity. Neuron (2008) 3.23
A role for glia in the progression of Rett's syndrome. Nature (2011) 3.18
Antidepressant actions of histone deacetylase inhibitors. J Neurosci (2009) 3.17
Rapid regulation of depression-related behaviours by control of midbrain dopamine neurons. Nature (2012) 3.15
The brain reward circuitry in mood disorders. Nat Rev Neurosci (2013) 3.08
The addicted synapse: mechanisms of synaptic and structural plasticity in nucleus accumbens. Trends Neurosci (2010) 3.02
Cocaine regulates MEF2 to control synaptic and behavioral plasticity. Neuron (2008) 3.01
Genome-wide analysis of chromatin regulation by cocaine reveals a role for sirtuins. Neuron (2009) 2.97
CREB modulates excitability of nucleus accumbens neurons. Nat Neurosci (2006) 2.95
Regulation of dopaminergic transmission and cocaine reward by the Clock gene. Proc Natl Acad Sci U S A (2005) 2.95
Early life programming and neurodevelopmental disorders. Biol Psychiatry (2010) 2.93
Antidepressant effect of optogenetic stimulation of the medial prefrontal cortex. J Neurosci (2010) 2.84
A core-BRAF35 complex containing histone deacetylase mediates repression of neuronal-specific genes. Proc Natl Acad Sci U S A (2002) 2.78
IRS2-Akt pathway in midbrain dopamine neurons regulates behavioral and cellular responses to opiates. Nat Neurosci (2006) 2.71
DeltaFosB: a molecular switch for long-term adaptation in the brain. Brain Res Mol Brain Res (2004) 2.67
Components of the REST/CoREST/histone deacetylase repressor complex are disrupted, modified, and translocated in HSV-1-infected cells. Proc Natl Acad Sci U S A (2005) 2.67
The orexigenic hormone ghrelin defends against depressive symptoms of chronic stress. Nat Neurosci (2008) 2.64
RGS9 modulates dopamine signaling in the basal ganglia. Neuron (2003) 2.61
Characterization of the CLEAR network reveals an integrated control of cellular clearance pathways. Hum Mol Genet (2011) 2.60
Linking molecules to mood: new insight into the biology of depression. Am J Psychiatry (2010) 2.54
Ralstonia metallidurans, a bacterium specifically adapted to toxic metals: towards a catalogue of metal-responsive genes. FEMS Microbiol Rev (2003) 2.48
A new binding motif for the transcriptional repressor REST uncovers large gene networks devoted to neuronal functions. J Neurosci (2007) 2.45
Phosphorylation of CBP mediates transcriptional activation by neural activity and CaM kinase IV. Neuron (2002) 2.45
Homeodomain interacting protein kinase 2 promotes apoptosis by downregulating the transcriptional corepressor CtBP. Cell (2003) 2.42
Methylphenidate treatment during pre- and periadolescence alters behavioral responses to emotional stimuli at adulthood. Biol Psychiatry (2003) 2.37
Brain-derived neurotrophic factor conditional knockouts show gender differences in depression-related behaviors. Biol Psychiatry (2006) 2.36
Distinct subclasses of medium spiny neurons differentially regulate striatal motor behaviors. Proc Natl Acad Sci U S A (2010) 2.36
Delta FosB mediates epigenetic desensitization of the c-fos gene after chronic amphetamine exposure. J Neurosci (2008) 2.34
Histone modifications at gene promoter regions in rat hippocampus after acute and chronic electroconvulsive seizures. J Neurosci (2004) 2.30