Published in Cell Mol Immunol on October 01, 2004
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An abundance of rare functional variants in 202 drug target genes sequenced in 14,002 people. Science (2012) 7.94
Loss of E-cadherin promotes metastasis via multiple downstream transcriptional pathways. Cancer Res (2008) 7.91
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Epithelial-mesenchymal plasticity in carcinoma metastasis. Genes Dev (2013) 3.63
Resting CD4+ T cells from human immunodeficiency virus type 1 (HIV-1)-infected individuals carry integrated HIV-1 genomes within actively transcribed host genes. J Virol (2004) 3.17
Straightening Caenorhabditis elegans images. Bioinformatics (2007) 3.13
Combinatorial development of biomaterials for clonal growth of human pluripotent stem cells. Nat Mater (2010) 3.11
CD44 splice isoform switching in human and mouse epithelium is essential for epithelial-mesenchymal transition and breast cancer progression. J Clin Invest (2011) 2.90
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Monitoring avian influenza A(H7N9) virus through national influenza-like illness surveillance, China. Emerg Infect Dis (2013) 2.61
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Estradiol-regulated microRNAs control estradiol response in breast cancer cells. Nucleic Acids Res (2009) 2.27
Insulin signaling meets vesicle traffic of GLUT4 at a plasma-membrane-activated fusion step. Cell Metab (2005) 2.20
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Comprehensive comparison of three commercial human whole-exome capture platforms. Genome Biol (2011) 2.15
Whole-genome sequencing identifies recurrent mutations in hepatocellular carcinoma. Genome Res (2013) 2.12
Activation of STAT6 by STING is critical for antiviral innate immunity. Cell (2011) 2.08
Geometric strategies for neuroanatomic analysis from MRI. Neuroimage (2004) 2.07
Selective control of cortical axonal spikes by a slowly inactivating K+ current. Proc Natl Acad Sci U S A (2007) 2.04
Genome-wide association study identifies eight new risk loci for polycystic ovary syndrome. Nat Genet (2012) 2.02
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Triptolide inhibits the growth and metastasis of solid tumors. Mol Cancer Ther (2003) 1.95
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Th9 cells promote antitumor immune responses in vivo. J Clin Invest (2012) 1.80
Patterns of segmental duplication in the human genome. Mol Biol Evol (2004) 1.76
A novel role for TRPM8 in visceral afferent function. Pain (2011) 1.74
Twist and epithelial-mesenchymal transition are induced by the EBV oncoprotein latent membrane protein 1 and are associated with metastatic nasopharyngeal carcinoma. Cancer Res (2007) 1.69
Mer receptor tyrosine kinase signaling participates in platelet function. Arterioscler Thromb Vasc Biol (2004) 1.67
Visualizing extravasation dynamics of metastatic tumor cells. J Cell Sci (2010) 1.67
Syndrome differentiation in modern research of traditional Chinese medicine. J Ethnopharmacol (2012) 1.62
Myeloma cell line-derived, pooled heat shock proteins as a universal vaccine for immunotherapy of multiple myeloma. Blood (2009) 1.61
Enhancement of radiation cytotoxicity in breast-cancer cells by localized attachment of gold nanoparticles. Small (2008) 1.60
Cross-cultural differences in children's choices, categorizations, and evaluations of truths and lies. Dev Psychol (2007) 1.59
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Epidemiology of hand, foot, and mouth disease and genotype characterization of Enterovirus 71 in Jiangsu, China. J Clin Virol (2010) 1.58
Macrophages are an abundant component of myeloma microenvironment and protect myeloma cells from chemotherapy drug-induced apoptosis. Blood (2009) 1.58
A caspase cascade regulating developmental axon degeneration. J Neurosci (2012) 1.57
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DLK initiates a transcriptional program that couples apoptotic and regenerative responses to axonal injury. Proc Natl Acad Sci U S A (2013) 1.53
Alcohol exposure alters DNA methylation profiles in mouse embryos at early neurulation. Epigenetics (2009) 1.53
Genome-wide association analysis of thirty one production, health, reproduction and body conformation traits in contemporary U.S. Holstein cows. BMC Genomics (2011) 1.52
Enhanced serodiagnostic utility of novel Mycobacterium tuberculosis polyproteins. J Infect (2012) 1.52
The Wilms tumor gene, Wt1, is critical for mouse spermatogenesis via regulation of sertoli cell polarity and is associated with non-obstructive azoospermia in humans. PLoS Genet (2013) 1.52
In vivo reduction of amyloid-beta by a mutant copper transporter. Proc Natl Acad Sci U S A (2003) 1.52
Measuring data abstraction quality in multiresolution visualizations. IEEE Trans Vis Comput Graph (2006) 1.51
The CNS glycoprotein Shadoo has PrP(C)-like protective properties and displays reduced levels in prion infections. EMBO J (2007) 1.49
Meta-analysis followed by replication identifies loci in or near CDKN1B, TET3, CD80, DRAM1, and ARID5B as associated with systemic lupus erythematosus in Asians. Am J Hum Genet (2012) 1.49
The human glomerular podocyte is a novel target for insulin action. Diabetes (2005) 1.49
Histone deacetylase inhibitor depsipeptide activates silenced genes through decreasing both CpG and H3K9 methylation on the promoter. Mol Cell Biol (2008) 1.48
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Dissolution of arterial platelet thrombi in vivo with a bifunctional platelet GPIIIa49-66 ligand which specifically targets the platelet thrombus. Blood (2010) 1.47
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Shox2 is essential for the differentiation of cardiac pacemaker cells by repressing Nkx2-5. Dev Biol (2009) 1.46
Association between two polymorphisms of ABCB1 and breast cancer risk in the current studies: a meta-analysis. Breast Cancer Res Treat (2010) 1.46
Novel arylimidamides for treatment of visceral leishmaniasis. Antimicrob Agents Chemother (2010) 1.45
5-amino-imidazole carboxamide riboside increases glucose transport and cell-surface GLUT4 content in skeletal muscle from subjects with type 2 diabetes. Diabetes (2003) 1.45
Clinicopathological features of gastric glomus tumor. World J Gastroenterol (2010) 1.44
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Genome-wide association analysis of total cholesterol and high-density lipoprotein cholesterol levels using the Framingham heart study data. BMC Med Genet (2010) 1.41
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A systematic review assessing the effectiveness of alendronate in reducing periprosthetic bone loss after cementless primary THA. Orthopedics (2011) 1.41
Association between polymorphisms of the ataxia telangiectasia mutated gene and breast cancer risk: evidence from the current studies. Breast Cancer Res Treat (2010) 1.40
Activation of Rap1B by G(i) family members in platelets. J Biol Chem (2002) 1.39
GlcNAcylation plays an essential role in breast cancer metastasis. Cancer Res (2010) 1.39
Intravenous Therapies for Complex Regional Pain Syndrome: A Systematic Review. Anesth Analg (2016) 1.39
Arabidopsis G-protein interactome reveals connections to cell wall carbohydrates and morphogenesis. Mol Syst Biol (2011) 1.38
Metastasis-associated in colon cancer-1 upregulation predicts a poor prognosis of gastric cancer, and promotes tumor cell proliferation and invasion. Int J Cancer (2013) 1.38
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A novel treatment strategy targeting Aurora kinases in acute myelogenous leukemia. Mol Cancer Ther (2007) 1.36
Claudin-4 forms paracellular chloride channel in the kidney and requires claudin-8 for tight junction localization. Proc Natl Acad Sci U S A (2010) 1.36
AtNUDT7, a negative regulator of basal immunity in Arabidopsis, modulates two distinct defense response pathways and is involved in maintaining redox homeostasis. Plant Physiol (2007) 1.32
Pre-ART levels of inflammation and coagulation markers are strong predictors of death in a South African cohort with advanced HIV disease. PLoS One (2012) 1.31
Overexpression of SATB1 in laryngeal squamous cell carcinoma. ORL J Otorhinolaryngol Relat Spec (2010) 1.29