Published in Mol Cell Proteomics on December 12, 2005
TDP-43 and FUS/TLS: emerging roles in RNA processing and neurodegeneration. Hum Mol Genet (2010) 5.75
mRNA localization: gene expression in the spatial dimension. Cell (2009) 5.50
Translational control of long-lasting synaptic plasticity and memory. Neuron (2009) 4.77
Staufen- and FMRP-containing neuronal RNPs are structurally and functionally related to somatic P bodies. Neuron (2006) 3.05
Gains or losses: molecular mechanisms of TDP43-mediated neurodegeneration. Nat Rev Neurosci (2011) 2.84
Cytoplasmic mislocalization of TDP-43 is toxic to neurons and enhanced by a mutation associated with familial amyotrophic lateral sclerosis. J Neurosci (2010) 2.73
Global analysis of TDP-43 interacting proteins reveals strong association with RNA splicing and translation machinery. J Proteome Res (2010) 2.35
Single β-actin mRNA detection in neurons reveals a mechanism for regulating its translatability. Science (2014) 2.23
Mutant induced pluripotent stem cell lines recapitulate aspects of TDP-43 proteinopathies and reveal cell-specific vulnerability. Proc Natl Acad Sci U S A (2012) 2.14
TDP-43 mediates degeneration in a novel Drosophila model of disease caused by mutations in VCP/p97. J Neurosci (2010) 2.05
Functional mapping of the interaction between TDP-43 and hnRNP A2 in vivo. Nucleic Acids Res (2009) 1.77
Spatially restricting gene expression by local translation at synapses. Trends Neurosci (2010) 1.74
In the right place at the right time: visualizing and understanding mRNA localization. Nat Rev Mol Cell Biol (2014) 1.72
Control of c-myc mRNA stability by IGF2BP1-associated cytoplasmic RNPs. RNA (2008) 1.63
Neurodegeneration the RNA way. Prog Neurobiol (2011) 1.43
Misregulated RNA processing in amyotrophic lateral sclerosis. Brain Res (2012) 1.42
TDRD3, a novel Tudor domain-containing protein, localizes to cytoplasmic stress granules. Hum Mol Genet (2008) 1.36
Cytoplasmic intron sequence-retaining transcripts can be dendritically targeted via ID element retrotransposons. Neuron (2011) 1.32
The RNA binding protein hnRNP Q modulates the utilization of exon 7 in the survival motor neuron 2 (SMN2) gene. Mol Cell Biol (2008) 1.27
Neuronal mRNAs travel singly into dendrites. Proc Natl Acad Sci U S A (2012) 1.25
The ALS disease protein TDP-43 is actively transported in motor neuron axons and regulates axon outgrowth. Hum Mol Genet (2012) 1.25
Subcellular communication through RNA transport and localized protein synthesis. Traffic (2010) 1.22
Dynamics of axonal mRNA transport and implications for peripheral nerve regeneration. Exp Neurol (2009) 1.21
Review: transactive response DNA-binding protein 43 (TDP-43): mechanisms of neurodegeneration. Neuropathol Appl Neurobiol (2010) 1.19
Reactivation of stalled polyribosomes in synaptic plasticity. Proc Natl Acad Sci U S A (2013) 1.18
Early endosome motility spatially organizes polysome distribution. J Cell Biol (2014) 1.18
Axonal transport proteomics reveals mobilization of translation machinery to the lesion site in injured sciatic nerve. Mol Cell Proteomics (2009) 1.13
Shotgun proteomics in neuroscience. Neuron (2009) 1.13
A HuD-ZBP1 ribonucleoprotein complex localizes GAP-43 mRNA into axons through its 3' untranslated region AU-rich regulatory element. J Neurochem (2013) 1.10
Dynamic association of the fragile X mental retardation protein as a messenger ribonucleoprotein between microtubules and polyribosomes. Mol Biol Cell (2007) 1.10
A host RNA helicase-like protein, AtRH8, interacts with the potyviral genome-linked protein, VPg, associates with the virus accumulation complex, and is essential for infection. Plant Physiol (2009) 1.08
The nuclear transcription factor RARalpha associates with neuronal RNA granules and suppresses translation. J Biol Chem (2008) 1.06
Quantitative analysis of the detergent-insoluble brain proteome in frontotemporal lobar degeneration using SILAC internal standards. J Proteome Res (2012) 1.05
Coaggregation of RNA-binding proteins in a model of TDP-43 proteinopathy with selective RGG motif methylation and a role for RRM1 ubiquitination. PLoS One (2012) 1.05
RNA binding proteins accumulate at the postsynaptic density with synaptic activity. J Neurosci (2012) 1.02
In cultured oligodendrocytes the A/B-type hnRNP CBF-A accompanies MBP mRNA bound to mRNA trafficking sequences. Mol Biol Cell (2008) 1.00
Multiplexed RNA trafficking in oligodendrocytes and neurons. Biochim Biophys Acta (2008) 0.98
mRNA localization: an orchestration of assembly, traffic and synthesis. Traffic (2012) 0.94
Proteomics of dense core secretory vesicles reveal distinct protein categories for secretion of neuroeffectors for cell-cell communication. J Proteome Res (2010) 0.93
FMRP and Ataxin-2 function together in long-term olfactory habituation and neuronal translational control. Proc Natl Acad Sci U S A (2013) 0.91
Multistep process of FUS aggregation in the cell cytoplasm involves RNA-dependent and RNA-independent mechanisms. Hum Mol Genet (2014) 0.90
Regulation of protein levels in subcellular domains through mRNA transport and localized translation. Mol Cell Proteomics (2010) 0.89
Cellular human CLE/C14orf166 protein interacts with influenza virus polymerase and is required for viral replication. J Virol (2011) 0.89
hCLE/C14orf166 associates with DDX1-HSPC117-FAM98B in a novel transcription-dependent shuttling RNA-transporting complex. PLoS One (2014) 0.88
In neurons, activity-dependent association of dendritically transported mRNA transcripts with the transacting factor CBF-A is mediated by A2RE/RTS elements. Mol Biol Cell (2011) 0.86
Molecular composition of staufen2-containing ribonucleoproteins in embryonic rat brain. PLoS One (2010) 0.86
Spatial regulation of translation through RNA localization. F1000 Biol Rep (2012) 0.85
Drosophila Syncrip binds the gurken mRNA localisation signal and regulates localised transcripts during axis specification. Biol Open (2012) 0.85
Fragile X related protein 1 clusters with ribosomes and messenger RNAs at a subset of dendritic spines in the mouse hippocampus. PLoS One (2011) 0.84
KIF1Bβ transports dendritically localized mRNPs in neurons and is recruited to synapses in an activity-dependent manner. Cell Mol Life Sci (2012) 0.83
Decoding neuroproteomics: integrating the genome, translatome and functional anatomy. Nat Neurosci (2014) 0.83
Protein methylation and stress granules: posttranslational remodeler or innocent bystander? Mol Biol Int (2011) 0.83
Protein kinase KIS localizes to RNA granules and enhances local translation. Mol Cell Biol (2008) 0.83
Poly(A) RNA-binding proteins and polyadenosine RNA: new members and novel functions. Wiley Interdiscip Rev RNA (2014) 0.83
Increasing our understanding of human cognition through the study of Fragile X Syndrome. Dev Neurobiol (2013) 0.82
Translation and silencing in RNA granules: a tale of sand grains. Front Mol Neurosci (2014) 0.80
Neuronal-specific overexpression of a mutant valosin-containing protein associated with IBMPFD promotes aberrant ubiquitin and TDP-43 accumulation and cognitive dysfunction in transgenic mice. Am J Pathol (2013) 0.79
Drosophila Syncrip modulates the expression of mRNAs encoding key synaptic proteins required for morphology at the neuromuscular junction. RNA (2014) 0.78
Proteostasis and RNA Binding Proteins in Synaptic Plasticity and in the Pathogenesis of Neuropsychiatric Disorders. Neural Plast (2016) 0.78
A comparative quantitative assessment of axonal and dendritic mRNA transport in maturing hippocampal neurons. PLoS One (2013) 0.77
Hop-on hop-off: polysomes take a tour of the cell on endosomes. J Cell Biol (2014) 0.77
Caprin controls follicle stem cell fate in the Drosophila ovary. PLoS One (2012) 0.76
FXR1P limits long-term memory, long-lasting synaptic potentiation, and de novo GluA2 translation. Cell Rep (2014) 0.76
Neuronal activity induces synaptic delivery of hnRNP A2/B1 by a BDNF-dependent mechanism in cultured hippocampal neurons. PLoS One (2014) 0.76
Translation initiation of the HIV-1 mRNA. Translation (Austin) (2014) 0.76
Ubiquitin ligase TRIM3 controls hippocampal plasticity and learning by regulating synaptic γ-actin levels. J Cell Biol (2015) 0.76
hCLE/C14orf166, a cellular protein required for viral replication, is incorporated into influenza virus particles. Sci Rep (2016) 0.75
Amyotrophic lateral sclerosis-linked mutations increase the viscosity of liquid-like TDP-43 RNP granules in neurons. Proc Natl Acad Sci U S A (2017) 0.75
RNA-binding proteins in eye development and disease: implication of conserved RNA granule components. Wiley Interdiscip Rev RNA (2016) 0.75
Tracking the Fragile X Mental Retardation Protein in a Highly Ordered Neuronal RiboNucleoParticles Population: A Link between Stalled Polyribosomes and RNA Granules. PLoS Genet (2016) 0.75
Visualization of newly synthesized neuronal RNA in vitro and in vivo using click-chemistry. RNA Biol (2016) 0.75
Control of mRNA Translation in ALS Proteinopathy. Front Mol Neurosci (2017) 0.75
Characterization of Soft Amyloid Cores in Human Prion-Like Proteins. Sci Rep (2017) 0.75
Long-term memory consolidation: The role of RNA-binding proteins with prion-like domains. RNA Biol (2016) 0.75
The InterPro Database, 2003 brings increased coverage and new features. Nucleic Acids Res (2003) 24.72
Integrative annotation of 21,037 human genes validated by full-length cDNA clones. PLoS Biol (2004) 7.17
Mitochondria: more than just a powerhouse. Curr Biol (2006) 6.76
Translational control of long-lasting synaptic plasticity and memory. Neuron (2009) 4.77
Quantitative proteomics analysis of the secretory pathway. Cell (2006) 3.63
eIF2alpha phosphorylation bidirectionally regulates the switch from short- to long-term synaptic plasticity and memory. Cell (2007) 3.46
Cortical GABA interneurons in neurovascular coupling: relays for subcortical vasoactive pathways. J Neurosci (2004) 3.44
The Proteome Analysis database: a tool for the in silico analysis of whole proteomes. Nucleic Acids Res (2003) 3.29
Autism-related deficits via dysregulated eIF4E-dependent translational control. Nature (2012) 3.13
Applications of InterPro in protein annotation and genome analysis. Brief Bioinform (2002) 3.03
Astrocytes are endogenous regulators of basal transmission at central synapses. Cell (2011) 2.97
Tandem MS analysis of brain clathrin-coated vesicles reveals their critical involvement in synaptic vesicle recycling. Proc Natl Acad Sci U S A (2004) 2.78
Synapse- and stimulus-specific local translation during long-term neuronal plasticity. Science (2009) 2.74
Translational control of hippocampal synaptic plasticity and memory by the eIF2alpha kinase GCN2. Nature (2005) 2.67
InterPro: an integrated documentation resource for protein families, domains and functional sites. Brief Bioinform (2002) 2.66
Mutant huntingtin impairs axonal trafficking in mammalian neurons in vivo and in vitro. Mol Cell Biol (2004) 2.65
Staufen1 regulates diverse classes of mammalian transcripts. EMBO J (2007) 2.18
The cellular trafficking of the secretory proprotein convertase PCSK9 and its dependence on the LDLR. Traffic (2007) 2.09
Enthoprotin: a novel clathrin-associated protein identified through subcellular proteomics. J Cell Biol (2002) 1.98
The Connecdenn DENN domain: a GEF for Rab35 mediating cargo-specific exit from early endosomes. Mol Cell (2010) 1.97
GABAergic network activation of glial cells underlies hippocampal heterosynaptic depression. J Neurosci (2006) 1.93
DENN domain proteins: regulators of Rab GTPases. J Biol Chem (2011) 1.81
De novo mutations in FOXP1 in cases with intellectual disability, autism, and language impairment. Am J Hum Genet (2010) 1.79
Complete rescue of cerebrovascular function in aged Alzheimer's disease transgenic mice by antioxidants and pioglitazone, a peroxisome proliferator-activated receptor gamma agonist. J Neurosci (2008) 1.73
ENTH/ANTH proteins and clathrin-mediated membrane budding. J Cell Sci (2004) 1.66
The ubiquitin ligase itch is auto-ubiquitylated in vivo and in vitro but is protected from degradation by interacting with the deubiquitylating enzyme FAM/USP9X. J Biol Chem (2006) 1.62
SH3 domains from a subset of BAR proteins define a Ubl-binding domain and implicate parkin in synaptic ubiquitination. Mol Cell (2009) 1.59
Interaction of Staufen1 with the 5' end of mRNA facilitates translation of these RNAs. Nucleic Acids Res (2005) 1.57
Developmental expression of Ca2+-permeable AMPA receptors underlies depolarization-induced long-term depression at mossy fiber CA3 pyramid synapses. J Neurosci (2007) 1.56
Interneuron Diversity series: Hippocampal interneuron classifications--making things as simple as possible, not simpler. Trends Neurosci (2003) 1.55
DNAJC13 mutations in Parkinson disease. Hum Mol Genet (2013) 1.54
Mutations in SYNGAP1 cause intellectual disability, autism, and a specific form of epilepsy by inducing haploinsufficiency. Hum Mutat (2012) 1.50
Dissection of the endogenous cellular pathways of PCSK9-induced low density lipoprotein receptor degradation: evidence for an intracellular route. J Biol Chem (2009) 1.49
Mammalian polynucleotide phosphorylase is an intermembrane space RNase that maintains mitochondrial homeostasis. Mol Cell Biol (2006) 1.49
Intracellular trafficking of RNA in neurons. Traffic (2006) 1.47
Huntingtin interacting protein 1 (HIP1) regulates clathrin assembly through direct binding to the regulatory region of the clathrin light chain. J Biol Chem (2004) 1.47
The HECT domain ligase itch ubiquitinates endophilin and localizes to the trans-Golgi network and endosomal system. J Biol Chem (2003) 1.44
Specific subtypes of cortical GABA interneurons contribute to the neurovascular coupling response to basal forebrain stimulation. J Cereb Blood Flow Metab (2007) 1.42
Developmental and target-dependent regulation of vesicular glutamate transporter expression by dopamine neurons. J Neurosci (2008) 1.39
Compartmentalized Ca(2+) channel regulation at divergent mossy-fiber release sites underlies target cell-dependent plasticity. Neuron (2006) 1.38
Postnatal deamidation of 4E-BP2 in brain enhances its association with raptor and alters kinetics of excitatory synaptic transmission. Mol Cell (2010) 1.38
Staufen2 isoforms localize to the somatodendritic domain of neurons and interact with different organelles. J Cell Sci (2002) 1.37
TUC-4b, a novel TUC family variant, regulates neurite outgrowth and associates with vesicles in the growth cone. J Neurosci (2003) 1.33
Connecdenn, a novel DENN domain-containing protein of neuronal clathrin-coated vesicles functioning in synaptic vesicle endocytosis. J Neurosci (2006) 1.33
Identification of Staufen in the human immunodeficiency virus type 1 Gag ribonucleoprotein complex and a role in generating infectious viral particles. Mol Cell Biol (2004) 1.31
Clathrin light chains function in mannose phosphate receptor trafficking via regulation of actin assembly. Proc Natl Acad Sci U S A (2007) 1.30
Non-stoichiometric relationship between clathrin heavy and light chains revealed by quantitative comparative proteomics of clathrin-coated vesicles from brain and liver. Mol Cell Proteomics (2005) 1.29
Definition of the consensus motif recognized by gamma-adaptin ear domains. J Biol Chem (2003) 1.29
Trafficking of HIV-1 RNA is mediated by heterogeneous nuclear ribonucleoprotein A2 expression and impacts on viral assembly. Traffic (2006) 1.29
Isoform specificity of PKC translocation in living Aplysia sensory neurons and a role for Ca2+-dependent PKC APL I in the induction of intermediate-term facilitation. J Neurosci (2006) 1.27
Liver X receptor beta (LXRbeta): a link between beta-sitosterol and amyotrophic lateral sclerosis-Parkinson's dementia. Proc Natl Acad Sci U S A (2008) 1.26
Structural definition of the F-actin-binding THATCH domain from HIP1R. Nat Struct Mol Biol (2006) 1.26
Skeletal abnormalities in Pth-null mice are influenced by dietary calcium. Endocrinology (2003) 1.26
Intersectin-1L nucleotide exchange factor regulates secretory granule exocytosis by activating Cdc42. EMBO J (2006) 1.26
HIP1 and HIP12 display differential binding to F-actin, AP2, and clathrin. Identification of a novel interaction with clathrin light chain. J Biol Chem (2002) 1.26
De novo SYNGAP1 mutations in nonsyndromic intellectual disability and autism. Biol Psychiatry (2011) 1.25
Glutamatergic Control of Microvascular Tone by Distinct GABA Neurons in the Cerebellum. J Neurosci (2006) 1.24
The brain-specific double-stranded RNA-binding protein Staufen2: nucleolar accumulation and isoform-specific exportin-5-dependent export. J Biol Chem (2004) 1.24
Mitochondrial dysfunction and Purkinje cell loss in autosomal recessive spastic ataxia of Charlevoix-Saguenay (ARSACS). Proc Natl Acad Sci U S A (2012) 1.23
mGluR1/5 subtype-specific calcium signalling and induction of long-term potentiation in rat hippocampal oriens/alveus interneurones. J Physiol (2006) 1.23
Kv4.3-mediated A-type K+ currents underlie rhythmic activity in hippocampal interneurons. J Neurosci (2007) 1.20
Interplay between Rab35 and Arf6 controls cargo recycling to coordinate cell adhesion and migration. J Cell Sci (2012) 1.19
Disruption of the endocytic protein HIP1 results in neurological deficits and decreased AMPA receptor trafficking. EMBO J (2003) 1.19
The DnaJ-domain protein RME-8 functions in endosomal trafficking. J Biol Chem (2005) 1.19
Reactivation of stalled polyribosomes in synaptic plasticity. Proc Natl Acad Sci U S A (2013) 1.18
Synapse-specific mGluR1-dependent long-term potentiation in interneurones regulates mouse hippocampal inhibition. J Physiol (2003) 1.18
Molecular mapping of the determinants involved in human Staufen-ribosome association. Biochem J (2002) 1.18
Scyl1, mutated in a recessive form of spinocerebellar neurodegeneration, regulates COPI-mediated retrograde traffic. J Biol Chem (2008) 1.17
High-resolution crystal structure of Arthrobacter aurescens chondroitin AC lyase: an enzyme-substrate complex defines the catalytic mechanism. J Mol Biol (2004) 1.14
Identification of a family of endocytic proteins that define a new alpha-adaptin ear-binding motif. EMBO Rep (2003) 1.14
Organellar proteomics to create the cell map. Curr Opin Cell Biol (2007) 1.13
Novel Staufen1 ribonucleoproteins prevent formation of stress granules but favour encapsidation of HIV-1 genomic RNA. J Cell Sci (2010) 1.12
Staufen1 regulation of protein synthesis-dependent long-term potentiation and synaptic function in hippocampal pyramidal cells. Mol Cell Biol (2008) 1.12
Rab35: GEFs, GAPs and effectors. Traffic (2013) 1.12
An activity-dependent switch to cap-independent translation triggered by eIF4E dephosphorylation. Nat Neurosci (2003) 1.09
The atypical protein kinase C in Aplysia can form a protein kinase M by cleavage. J Neurochem (2009) 1.09
The RNA-binding protein Staufen1 is increased in DM1 skeletal muscle and promotes alternative pre-mRNA splicing. J Cell Biol (2012) 1.09
The connecdenn family, Rab35 guanine nucleotide exchange factors interfacing with the clathrin machinery. J Biol Chem (2010) 1.09
Multiple serotonergic mechanisms contributing to sensitization in aplysia: evidence of diverse serotonin receptor subtypes. Learn Mem (2003) 1.09
Differential regulation of metabotropic glutamate receptor- and AMPA receptor-mediated dendritic Ca2+ signals by presynaptic and postsynaptic activity in hippocampal interneurons. J Neurosci (2005) 1.08
Role of protein kinase C in the induction and maintenance of serotonin-dependent enhancement of the glutamate response in isolated siphon motor neurons of Aplysia californica. J Neurosci (2009) 1.08
Structural basis of defects in the sacsin HEPN domain responsible for autosomal recessive spastic ataxia of Charlevoix-Saguenay (ARSACS). J Biol Chem (2011) 1.08
GABAB receptor- and metabotropic glutamate receptor-dependent cooperative long-term potentiation of rat hippocampal GABAA synaptic transmission. J Physiol (2003) 1.08
LXR agonists: new potential therapeutic drug for neurodegenerative diseases. Mol Neurobiol (2013) 1.07
Forskolin induction of late-LTP and up-regulation of 5' TOP mRNAs translation via mTOR, ERK, and PI3K in hippocampal pyramidal cells. J Neurochem (2008) 1.07
EphA4 is localized in clathrin-coated and synaptic vesicles in adult mouse brain. J Neurochem (2010) 1.07
PKC differentially translocates during spaced and massed training in Aplysia. J Neurosci (2009) 1.06
GTPase-mediated regulation of the unfolded protein response in Caenorhabditis elegans is dependent on the AAA+ ATPase CDC-48. Mol Cell Biol (2008) 1.06