Published in J Biol Chem on January 30, 2006
Molecular architecture of the 26S proteasome holocomplex determined by an integrative approach. Proc Natl Acad Sci U S A (2012) 3.42
Structural organization of the 19S proteasome lid: insights from MS of intact complexes. PLoS Biol (2006) 2.56
Substrate selection by the proteasome during degradation of protein complexes. Nat Chem Biol (2008) 1.61
Sizing large proteins and protein complexes by electrospray ionization mass spectrometry and ion mobility. J Am Soc Mass Spectrom (2007) 1.46
The proteasome antechamber maintains substrates in an unfolded state. Nature (2010) 1.34
The RNA exosome and proteasome: common principles of degradation control. Nat Rev Mol Cell Biol (2013) 1.12
Proteasomes and protein conjugation across domains of life. Nat Rev Microbiol (2011) 1.12
The structural dynamics of macromolecular processes. Curr Opin Cell Biol (2009) 1.12
Mass spectrometry of protein-ligand complexes: enhanced gas-phase stability of ribonuclease-nucleotide complexes. J Am Soc Mass Spectrom (2008) 1.00
Analyzing large protein complexes by structural mass spectrometry. J Vis Exp (2010) 0.97
The 20S proteasome splicing activity discovered by SpliceMet. PLoS Comput Biol (2010) 0.96
Quantitative time-resolved analysis reveals intricate, differential regulation of standard- and immuno-proteasomes. Elife (2015) 0.94
Newly folded substrates inside the molecular cage of the HtrA chaperone DegQ. Nat Struct Mol Biol (2012) 0.93
Structural basis for the assembly and gate closure mechanisms of the Mycobacterium tuberculosis 20S proteasome. EMBO J (2010) 0.86
Ultrastructure and morphology of midgut visceral muscle in early pupal Aedes aegypti mosquitoes. Tissue Cell (2007) 0.79
Prokaryotic proteasomes: nanocompartments of degradation. J Mol Microbiol Biotechnol (2013) 0.78
Modelling proteasome and proteasome regulator activities. Biomolecules (2014) 0.77
Degradation of oxidized proteins by the proteasome: Distinguishing between the 20S, 26S, and immunoproteasome proteolytic pathways. Mol Aspects Med (2016) 0.77
Mass spectrometry coupled experiments and protein structure modeling methods. Int J Mol Sci (2013) 0.76
Crystallization and preliminary X-ray analysis of the Thermoplasma acidophilum 20S proteasome in complex with protein substrates. Acta Crystallogr Sect F Struct Biol Cryst Commun (2008) 0.75
Mechanism of auxin perception by the TIR1 ubiquitin ligase. Nature (2007) 8.21
Structural studies by electron tomography: from cells to molecules. Annu Rev Biochem (2005) 5.56
Macromolecular architecture in eukaryotic cells visualized by cryoelectron tomography. Science (2002) 5.28
The protofilament structure of insulin amyloid fibrils. Proc Natl Acad Sci U S A (2002) 4.08
Targeting C-reactive protein for the treatment of cardiovascular disease. Nature (2006) 4.07
A tandem mass spectrometer for improved transmission and analysis of large macromolecular assemblies. Anal Chem (2002) 3.83
Three-dimensional structure of herpes simplex virus from cryo-electron tomography. Science (2003) 3.82
Amyloid-β protein oligomerization and the importance of tetramers and dodecamers in the aetiology of Alzheimer's disease. Nat Chem (2009) 3.66
Determining the stoichiometry and interactions of macromolecular assemblies from mass spectrometry. Nat Protoc (2007) 3.64
Nuclear pore complex structure and dynamics revealed by cryoelectron tomography. Science (2004) 3.61
Ion mobility-mass spectrometry analysis of large protein complexes. Nat Protoc (2008) 3.51
In vitro reconstitution of the human RISC-loading complex. Proc Natl Acad Sci U S A (2008) 3.43
Molecular architecture of the 26S proteasome holocomplex determined by an integrative approach. Proc Natl Acad Sci U S A (2012) 3.42
Evidence for macromolecular protein rings in the absence of bulk water. Science (2005) 3.26
The molecular sociology of the cell. Nature (2007) 3.23
Retrovirus envelope protein complex structure in situ studied by cryo-electron tomography. Proc Natl Acad Sci U S A (2005) 3.17
TOM software toolbox: acquisition and analysis for electron tomography. J Struct Biol (2005) 3.16
ATP hydrolysis by the proteasome regulatory complex PAN serves multiple functions in protein degradation. Mol Cell (2003) 3.14
Snapshots of nuclear pore complexes in action captured by cryo-electron tomography. Nature (2007) 2.99
From words to literature in structural proteomics. Nature (2003) 2.80
Structures of SAS-6 suggest its organization in centrioles. Science (2011) 2.67
Structure of an Hsp90-Cdc37-Cdk4 complex. Mol Cell (2006) 2.62
Collision cross sections of proteins and their complexes: a calibration framework and database for gas-phase structural biology. Anal Chem (2010) 2.62
Protein complexes in the gas phase: technology for structural genomics and proteomics. Chem Rev (2007) 2.57
Structural organization of the 19S proteasome lid: insights from MS of intact complexes. PLoS Biol (2006) 2.56
Mass spectrometry reveals modularity and a complete subunit interaction map of the eukaryotic translation factor eIF3. Proc Natl Acad Sci U S A (2008) 2.50
Micelles protect membrane complexes from solution to vacuum. Science (2008) 2.40
Molecular recycling within amyloid fibrils. Nature (2005) 2.39
The role of mass spectrometry in structure elucidation of dynamic protein complexes. Annu Rev Biochem (2007) 2.39
Mass measurements of increased accuracy resolve heterogeneous populations of intact ribosomes. J Am Chem Soc (2006) 2.31
Symmetrical modularity of the COP9 signalosome complex suggests its multifunctionality. Structure (2009) 2.30
Correlative microscopy: bridging the gap between fluorescence light microscopy and cryo-electron tomography. J Struct Biol (2007) 2.29
Assembly reflects evolution of protein complexes. Nature (2008) 2.27
Structural insights into RNA processing by the human RISC-loading complex. Nat Struct Mol Biol (2009) 2.19
The Fas-FADD death domain complex structure reveals the basis of DISC assembly and disease mutations. Nat Struct Mol Biol (2010) 2.08
Structure of the 26S proteasome from Schizosaccharomyces pombe at subnanometer resolution. Proc Natl Acad Sci U S A (2010) 2.05
Near-atomic resolution structural model of the yeast 26S proteasome. Proc Natl Acad Sci U S A (2012) 2.04
Structural insights into the activity of enhancer-binding proteins. Science (2005) 2.04
Identification of macromolecular complexes in cryoelectron tomograms of phantom cells. Proc Natl Acad Sci U S A (2002) 1.98
Tandem mass spectrometry reveals the quaternary organization of macromolecular assemblies. Chem Biol (2006) 1.96
Crystal structures of truncated alphaA and alphaB crystallins reveal structural mechanisms of polydispersity important for eye lens function. Protein Sci (2010) 1.95
Structural basis for protein-protein interactions in the 14-3-3 protein family. Proc Natl Acad Sci U S A (2006) 1.95
Three-dimensional architecture of murine rod outer segments determined by cryoelectron tomography. J Cell Biol (2007) 1.92
Visualizing cells at the nanoscale. Trends Biochem Sci (2008) 1.91
Focused ion beam micromachining of eukaryotic cells for cryoelectron tomography. Proc Natl Acad Sci U S A (2012) 1.89
The native 3D organization of bacterial polysomes. Cell (2009) 1.88
An oligomeric signaling platform formed by the Toll-like receptor signal transducers MyD88 and IRAK-4. J Biol Chem (2009) 1.85
3D structure of eukaryotic flagella in a quiescent state revealed by cryo-electron tomography. Proc Natl Acad Sci U S A (2005) 1.83
Insights into the molecular architecture of the 26S proteasome. Proc Natl Acad Sci U S A (2009) 1.81
Structural basis for the subunit assembly of the anaphase-promoting complex. Nature (2011) 1.80
A visual approach to proteomics. Nat Rev Mol Cell Biol (2006) 1.79
Recognition of a signal peptide by the signal recognition particle. Nature (2010) 1.77
Polydispersity of a mammalian chaperone: mass spectrometry reveals the population of oligomers in alphaB-crystallin. Proc Natl Acad Sci U S A (2003) 1.76
Subunit architecture of multimeric complexes isolated directly from cells. EMBO Rep (2006) 1.75
The co-chaperone p23 arrests the Hsp90 ATPase cycle to trap client proteins. J Mol Biol (2005) 1.74
Structure of the CRISPR interference complex CSM reveals key similarities with cascade. Mol Cell (2013) 1.74
Cryo-electron tomography reveals the cytoskeletal structure of Spiroplasma melliferum. Science (2005) 1.72
Structural characterization of the human eukaryotic initiation factor 3 protein complex by mass spectrometry. Mol Cell Proteomics (2007) 1.71
Protein complexes of the Escherichia coli cell envelope. J Biol Chem (2005) 1.69
Cryo-electron tomography: the challenge of doing structural biology in situ. J Cell Biol (2013) 1.68
Formation of cristae and crista junctions in mitochondria depends on antagonism between Fcj1 and Su e/g. J Cell Biol (2009) 1.66
A camelid antibody fragment inhibits the formation of amyloid fibrils by human lysozyme. Nature (2003) 1.66
Local cooperativity in the unfolding of an amyloidogenic variant of human lysozyme. Nat Struct Biol (2002) 1.64
Quaternary dynamics and plasticity underlie small heat shock protein chaperone function. Proc Natl Acad Sci U S A (2010) 1.63
Mass spectrometry of macromolecular assemblies: preservation and dissociation. Curr Opin Struct Biol (2006) 1.62
Aspects of native proteins are retained in vacuum. Curr Opin Chem Biol (2006) 1.61
Studies of the RNA degradosome-organizing domain of the Escherichia coli ribonuclease RNase E. J Mol Biol (2004) 1.60
Organization of actin networks in intact filopodia. Curr Biol (2007) 1.59
The proteasomal subunit Rpn6 is a molecular clamp holding the core and regulatory subcomplexes together. Proc Natl Acad Sci U S A (2011) 1.57
Crystal structure of the proteasomal deubiquitylation module Rpn8-Rpn11. Proc Natl Acad Sci U S A (2014) 1.57
Mass spectrometry of membrane transporters reveals subunit stoichiometry and interactions. Nat Methods (2009) 1.51
Structural characterization of drug-like compounds by ion mobility mass spectrometry: comparison of theoretical and experimentally derived nitrogen collision cross sections. Anal Chem (2011) 1.51
Structural role of Sfi1p-centrin filaments in budding yeast spindle pole body duplication. J Cell Biol (2006) 1.51
Structure of the 26S proteasome with ATP-γS bound provides insights into the mechanism of nucleotide-dependent substrate translocation. Proc Natl Acad Sci U S A (2013) 1.50
Subunit exchange of multimeric protein complexes. Real-time monitoring of subunit exchange between small heat shock proteins by using electrospray mass spectrometry. J Biol Chem (2002) 1.50
Micromachining tools and correlative approaches for cellular cryo-electron tomography. J Struct Biol (2010) 1.49
Structural basis for the inhibition of activin signalling by follistatin. EMBO J (2006) 1.49
αB-crystallin polydispersity is a consequence of unbiased quaternary dynamics. J Mol Biol (2011) 1.48
Quantitative analysis of the native presynaptic cytomatrix by cryoelectron tomography. J Cell Biol (2010) 1.48
Defining the mechanism of polymerization in the serpinopathies. Proc Natl Acad Sci U S A (2010) 1.48
Cryo-electron tomography of vaccinia virus. Proc Natl Acad Sci U S A (2005) 1.48
The structure of human tripeptidyl peptidase II as determined by a hybrid approach. Structure (2012) 1.47
Ion mobility-mass spectrometry reveals long-lived, unfolded intermediates in the dissociation of protein complexes. Angew Chem Int Ed Engl (2007) 1.47
Structural evolution of p53, p63, and p73: implication for heterotetramer formation. Proc Natl Acad Sci U S A (2009) 1.46
Noise contributions in an inducible genetic switch: a whole-cell simulation study. PLoS Comput Biol (2011) 1.44
Observation of sequence specificity in the seeding of protein amyloid fibrils. Protein Sci (2004) 1.44
Evidence of direct cell-cell fusion in Borrelia by cryogenic electron tomography. Cell Microbiol (2011) 1.43
Localization of the proteasomal ubiquitin receptors Rpn10 and Rpn13 by electron cryomicroscopy. Proc Natl Acad Sci U S A (2012) 1.42
Mass spectrometry of intact membrane protein complexes. Nat Protoc (2013) 1.41
Phosphorylation of alphaB-crystallin alters chaperone function through loss of dimeric substructure. J Biol Chem (2004) 1.41
Automated segmentation of electron tomograms for a quantitative description of actin filament networks. J Struct Biol (2011) 1.39
Subunit architecture of intact protein complexes from mass spectrometry and homology modeling. Acc Chem Res (2008) 1.38
Ion mobility mass spectrometry of peptide ions: effects of drift gas and calibration strategies. Anal Chem (2012) 1.37
Deep classification of a large cryo-EM dataset defines the conformational landscape of the 26S proteasome. Proc Natl Acad Sci U S A (2014) 1.37
Class I HDACs share a common mechanism of regulation by inositol phosphates. Mol Cell (2013) 1.37
The proteasome antechamber maintains substrates in an unfolded state. Nature (2010) 1.34
Mimicking phosphorylation of alphaB-crystallin affects its chaperone activity. Biochem J (2007) 1.34
How to switch off a histidine kinase: crystal structure of Geobacillus stearothermophilus KinB with the inhibitor Sda. J Mol Biol (2008) 1.33