Published in Science on January 21, 2005
The structure of FtsZ filaments in vivo suggests a force-generating role in cell division. EMBO J (2007) 3.44
The bacterial cytoskeleton. Microbiol Mol Biol Rev (2006) 2.41
The bacterial actin-like cytoskeleton. Microbiol Mol Biol Rev (2006) 2.18
Sculpting the bacterial cell. Curr Biol (2009) 2.04
Bacterial growth and cell division: a mycobacterial perspective. Microbiol Mol Biol Rev (2008) 2.01
3-D ultrastructure of O. tauri: electron cryotomography of an entire eukaryotic cell. PLoS One (2007) 1.72
Protein structure by mechanical triangulation. Proc Natl Acad Sci U S A (2006) 1.65
Expedited approaches to whole cell electron tomography and organelle mark-up in situ in high-pressure frozen pancreatic islets. J Struct Biol (2007) 1.64
Cryo-electron tomography of bacteria: progress, challenges and future prospects. Nat Rev Microbiol (2009) 1.51
Molecular electron microscopy: state of the art and current challenges. ACS Chem Biol (2008) 1.41
Long helical filaments are not seen encircling cells in electron cryotomograms of rod-shaped bacteria. Biochem Biophys Res Commun (2011) 1.35
Complete genomes of two dipteran-associated spiroplasmas provided insights into the origin, dynamics, and impacts of viral invasion in spiroplasma. Genome Biol Evol (2013) 1.32
The structure and function of bacterial actin homologs. Cold Spring Harb Perspect Biol (2010) 1.27
Ignicoccus hospitalis and Nanoarchaeum equitans: ultrastructure, cell-cell interaction, and 3D reconstruction from serial sections of freeze-substituted cells and by electron cryotomography. Arch Microbiol (2008) 1.26
Cryo-electron tomography reveals the comparative three-dimensional architecture of Prochlorococcus, a globally important marine cyanobacterium. J Bacteriol (2007) 1.25
GTPase activity, structure, and mechanical properties of filaments assembled from bacterial cytoskeleton protein MreB. J Bacteriol (2006) 1.24
Filament structure, organization, and dynamics in MreB sheets. J Biol Chem (2010) 1.18
Comparison of metabolic capacities and inference of gene content evolution in mosquito-associated Spiroplasma diminutum and S. taiwanense. Genome Biol Evol (2013) 1.16
Three-dimensional imaging of the highly bent architecture of Bdellovibrio bacteriovorus by using cryo-electron tomography. J Bacteriol (2008) 1.14
Electron cryotomography. Cold Spring Harb Perspect Biol (2010) 1.12
Cryo-electron tomography of cells: connecting structure and function. Histochem Cell Biol (2008) 1.12
A new lineage of halophilic, wall-less, contractile bacteria from a brine-filled deep of the Red Sea. J Bacteriol (2008) 1.10
Spatially resolved shear distribution in microfluidic chip for studying force transduction mechanisms in cells. Lab Chip (2009) 1.08
Functional taxonomy of bacterial hyperstructures. Microbiol Mol Biol Rev (2007) 1.07
Native cellular architecture of Treponema denticola revealed by cryo-electron tomography. J Struct Biol (2008) 1.05
3D structure determination of native mammalian cells using cryo-FIB and cryo-electron tomography. J Struct Biol (2012) 1.01
Computational separation of conformational heterogeneity using cryo-electron tomography and 3D sub-volume averaging. J Struct Biol (2012) 0.98
Genome sequence of the Drosophila melanogaster male-killing Spiroplasma strain MSRO endosymbiont. MBio (2015) 0.96
Geometric constrains for detecting short actin filaments by cryogenic electron tomography. PMC Biophys (2010) 0.92
An actin homolog of the archaeon Thermoplasma acidophilum that retains the ancient characteristics of eukaryotic actin. J Bacteriol (2006) 0.90
Genome sequence of Haloplasma contractile, an unusual contractile bacterium from a deep-sea anoxic brine lake. J Bacteriol (2011) 0.89
Multidimensional view of the bacterial cytoskeleton. J Bacteriol (2013) 0.87
Deciphering morphological determinants of the helix-shaped Leptospira. J Bacteriol (2011) 0.86
A new view into prokaryotic cell biology from electron cryotomography. Nat Rev Microbiol (2016) 0.84
Thinning of large mammalian cells for cryo-TEM characterization by cryo-FIB milling. J Microsc (2012) 0.84
The scc spirochetal coiled-coil protein forms helix-like filaments and binds to nucleic acids generating nucleoprotein structures. J Bacteriol (2006) 0.83
A structural framework for a near-minimal form of life: mass and compositional analysis of the helical mollicute Spiroplasma melliferum BC3. PLoS One (2014) 0.81
Integrated Information and Prospects for Gliding Mechanism of the Pathogenic Bacterium Mycoplasma pneumoniae. Front Microbiol (2016) 0.79
The eukaryotic cell originated in the integration and redistribution of hyperstructures from communities of prokaryotic cells based on molecular complementarity. Int J Mol Sci (2009) 0.77
Route of intrabacterial nanotransportation system for CagA in Helicobacter pylori. Med Mol Morphol (2015) 0.77
Minicells, Back in Fashion. J Bacteriol (2016) 0.76
Surface traction and the dynamics of elastic rods at low Reynolds number. Phys Rev E Stat Nonlin Soft Matter Phys (2012) 0.75
Production and application of polyclonal and monoclonal antibodies against Spiroplasma eriocheiris. Sci Rep (2015) 0.75
High-resolution anatomy of a progressively pinching cell division. J Bacteriol (2005) 0.75
Controlled bacterial lysis for electron tomography of native cell membranes. Structure (2014) 0.75
Chemotaxis without Conventional Two-Component System, Based on Cell Polarity and Aerobic Conditions in Helicity-Switching Swimming of Spiroplasma eriocheiris. Front Microbiol (2017) 0.75
Structural studies by electron tomography: from cells to molecules. Annu Rev Biochem (2005) 5.56
Macromolecular architecture in eukaryotic cells visualized by cryoelectron tomography. Science (2002) 5.28
Atheroprotective communication between endothelial cells and smooth muscle cells through miRNAs. Nat Cell Biol (2012) 5.12
Proteome organization in a genome-reduced bacterium. Science (2009) 3.97
Three-dimensional structure of herpes simplex virus from cryo-electron tomography. Science (2003) 3.82
Nuclear pore complex structure and dynamics revealed by cryoelectron tomography. Science (2004) 3.61
Molecular architecture of the 26S proteasome holocomplex determined by an integrative approach. Proc Natl Acad Sci U S A (2012) 3.42
The molecular sociology of the cell. Nature (2007) 3.23
Retrovirus envelope protein complex structure in situ studied by cryo-electron tomography. Proc Natl Acad Sci U S A (2005) 3.17
TOM software toolbox: acquisition and analysis for electron tomography. J Struct Biol (2005) 3.16
ATP hydrolysis by the proteasome regulatory complex PAN serves multiple functions in protein degradation. Mol Cell (2003) 3.14
Snapshots of nuclear pore complexes in action captured by cryo-electron tomography. Nature (2007) 2.99
From words to literature in structural proteomics. Nature (2003) 2.80
Multiple large filament bundles observed in Caulobacter crescentus by electron cryotomography. Mol Microbiol (2006) 2.59
The molecular architecture of cadherins in native epidermal desmosomes. Nature (2007) 2.29
Correlative microscopy: bridging the gap between fluorescence light microscopy and cryo-electron tomography. J Struct Biol (2007) 2.29
Quantitative and spatio-temporal features of protein aggregation in Escherichia coli and consequences on protein quality control and cellular ageing. EMBO J (2010) 2.25
Human mitotic chromosomes consist predominantly of irregularly folded nucleosome fibres without a 30-nm chromatin structure. EMBO J (2012) 2.17
Structure of the 26S proteasome from Schizosaccharomyces pombe at subnanometer resolution. Proc Natl Acad Sci U S A (2010) 2.05
Near-atomic resolution structural model of the yeast 26S proteasome. Proc Natl Acad Sci U S A (2012) 2.04
Identification of macromolecular complexes in cryoelectron tomograms of phantom cells. Proc Natl Acad Sci U S A (2002) 1.98
Analysis of cryo-electron microscopy images does not support the existence of 30-nm chromatin fibers in mitotic chromosomes in situ. Proc Natl Acad Sci U S A (2008) 1.95
Three-dimensional architecture of murine rod outer segments determined by cryoelectron tomography. J Cell Biol (2007) 1.92
Visualizing cells at the nanoscale. Trends Biochem Sci (2008) 1.91
Classification of cryo-electron sub-tomograms using constrained correlation. J Struct Biol (2007) 1.91
Performance evaluation of image processing algorithms on the GPU. J Struct Biol (2008) 1.89
Focused ion beam micromachining of eukaryotic cells for cryoelectron tomography. Proc Natl Acad Sci U S A (2012) 1.89
The native 3D organization of bacterial polysomes. Cell (2009) 1.88
3D structure of eukaryotic flagella in a quiescent state revealed by cryo-electron tomography. Proc Natl Acad Sci U S A (2005) 1.83
Insights into the molecular architecture of the 26S proteasome. Proc Natl Acad Sci U S A (2009) 1.81
A visual approach to proteomics. Nat Rev Mol Cell Biol (2006) 1.79
Cryo-electron tomography: the challenge of doing structural biology in situ. J Cell Biol (2013) 1.68
Formation of cristae and crista junctions in mitochondria depends on antagonism between Fcj1 and Su e/g. J Cell Biol (2009) 1.66
Organization of actin networks in intact filopodia. Curr Biol (2007) 1.59
The proteasomal subunit Rpn6 is a molecular clamp holding the core and regulatory subcomplexes together. Proc Natl Acad Sci U S A (2011) 1.57
Crystal structure of the proteasomal deubiquitylation module Rpn8-Rpn11. Proc Natl Acad Sci U S A (2014) 1.57
Structure of the 26S proteasome with ATP-γS bound provides insights into the mechanism of nucleotide-dependent substrate translocation. Proc Natl Acad Sci U S A (2013) 1.50
Micromachining tools and correlative approaches for cellular cryo-electron tomography. J Struct Biol (2010) 1.49
Quantitative analysis of the native presynaptic cytomatrix by cryoelectron tomography. J Cell Biol (2010) 1.48
A visualization and segmentation toolbox for electron microscopy. J Struct Biol (2008) 1.48
Cryo-electron tomography of vaccinia virus. Proc Natl Acad Sci U S A (2005) 1.48
The structure of human tripeptidyl peptidase II as determined by a hybrid approach. Structure (2012) 1.47
Noise contributions in an inducible genetic switch: a whole-cell simulation study. PLoS Comput Biol (2011) 1.44
Evidence of direct cell-cell fusion in Borrelia by cryogenic electron tomography. Cell Microbiol (2011) 1.43
Localization of the proteasomal ubiquitin receptors Rpn10 and Rpn13 by electron cryomicroscopy. Proc Natl Acad Sci U S A (2012) 1.42
Evidence for short-range helical order in the 30-nm chromatin fibers of erythrocyte nuclei. Proc Natl Acad Sci U S A (2011) 1.40
Automated segmentation of electron tomograms for a quantitative description of actin filament networks. J Struct Biol (2011) 1.39
Deep classification of a large cryo-EM dataset defines the conformational landscape of the 26S proteasome. Proc Natl Acad Sci U S A (2014) 1.37
Visualization of macromolecular structures. Nat Methods (2010) 1.34
Multiscale imaging of neurons grown in culture: from light microscopy to cryo-electron tomography. J Struct Biol (2007) 1.32
Prospects of electron cryotomography to visualize macromolecular complexes inside cellular compartments: implications of crowding. Biophys Chem (2003) 1.30
Mapping 70S ribosomes in intact cells by cryoelectron tomography and pattern recognition. J Struct Biol (2006) 1.28
An atomic model AAA-ATPase/20S core particle sub-complex of the 26S proteasome. Biochem Biophys Res Commun (2009) 1.28
The three-dimensional organization of polyribosomes in intact human cells. Mol Cell (2010) 1.26
Structural analysis of Mycoplasma pneumoniae by cryo-electron tomography. J Struct Biol (2006) 1.24
20S proteasomes have the potential to keep substrates in store for continual degradation. J Biol Chem (2006) 1.20
Toward an integrated structural model of the 26S proteasome. Mol Cell Proteomics (2010) 1.19
Structure of hibernating ribosomes studied by cryoelectron tomography in vitro and in situ. J Cell Biol (2010) 1.19
Automated cryoelectron microscopy of "single particles" applied to the 26S proteasome. FEBS Lett (2007) 1.17
The catalytic activity of Ubp6 enhances maturation of the proteasomal regulatory particle. Mol Cell (2011) 1.17
Advancing cell biology through proteomics in space and time (PROSPECTS). Mol Cell Proteomics (2012) 1.15
Implementation and performance evaluation of reconstruction algorithms on graphics processors. J Struct Biol (2006) 1.14
Comparative cryo-electron tomography of pathogenic Lyme disease spirochetes. Mol Microbiol (2009) 1.14
Structural analysis of the 26S proteasome by cryoelectron tomography. Biochem Biophys Res Commun (2006) 1.13
VAT, the thermoplasma homolog of mammalian p97/VCP, is an N domain-regulated protein unfoldase. J Biol Chem (2005) 1.13
Opening windows into the cell: focused-ion-beam milling for cryo-electron tomography. Curr Opin Struct Biol (2013) 1.12
Cryo-electron tomography of cells: connecting structure and function. Histochem Cell Biol (2008) 1.12
Luminal particles within cellular microtubules. J Cell Biol (2006) 1.10
Morphological characterization of molecular complexes present in the synaptic cleft. Structure (2005) 1.06
Electron tomography of vitreous sections from cultured mammalian cells. J Struct Biol (2007) 1.06
The future is hybrid. J Struct Biol (2008) 1.05
Unveiling the long-held secrets of the 26S proteasome. Structure (2013) 1.05
Crystal structures of the Rhodococcus proteasome with and without its pro-peptides: implications for the role of the pro-peptide in proteasome assembly. J Mol Biol (2004) 1.05
Cryo-electron tomography reveals a critical role of RIM1α in synaptic vesicle tethering. J Cell Biol (2013) 1.05
Pyrodictium cannulae enter the periplasmic space but do not enter the cytoplasm, as revealed by cryo-electron tomography. J Struct Biol (2003) 1.04
Computer controlled cryo-electron microscopy--TOM² a software package for high-throughput applications. J Struct Biol (2011) 1.04
Classification of electron sub-tomograms with neural networks and its application to template-matching. J Struct Biol (2011) 1.03
Whole cell cryo-electron tomography reveals distinct disassembly intermediates of vaccinia virus. PLoS One (2007) 1.03
Cytoplasmic relaxation of active Eph controls ephrin shedding by ADAM10. PLoS Biol (2009) 1.03
Dynamic organization of the actin system in the motile cells of Dictyostelium. J Muscle Res Cell Motil (2002) 1.03
Visualization of cell microtubules in their native state. Biol Cell (2007) 1.02
Positioning of large organelles by a membrane- associated cytoskeleton in Plasmodium sporozoites. Cell Microbiol (2009) 1.02
Distinct in situ structures of the Borrelia flagellar motor. J Struct Biol (2009) 1.02
The N-terminal coiled coil of the Rhodococcus erythropolis ARC AAA ATPase is neither necessary for oligomerization nor nucleotide hydrolysis. J Struct Biol (2004) 1.01
Cryoelectron tomography reveals periodic material at the inner side of subpellicular microtubules in apicomplexan parasites. J Exp Med (2007) 1.01
Mass spectrometry reveals the missing links in the assembly pathway of the bacterial 20 S proteasome. J Biol Chem (2007) 1.00
Binary Pt-Si nanostructures prepared by focused electron-beam-induced deposition. ACS Nano (2011) 1.00
Maximum likelihood based classification of electron tomographic data. J Struct Biol (2010) 1.00
Localization of the regulatory particle subunit Sem1 in the 26S proteasome. Biochem Biophys Res Commun (2013) 0.96
Graphene oxide: a substrate for optimizing preparations of frozen-hydrated samples. J Struct Biol (2009) 0.96
Localization of protein complexes by pattern recognition. Methods Cell Biol (2007) 0.96
Xylanase attachment to the cell wall of the hyperthermophilic bacterium Thermotoga maritima. J Bacteriol (2007) 0.96
Alignator: a GPU powered software package for robust fiducial-less alignment of cryo tilt-series. J Struct Biol (2010) 0.95
The three-dimensional molecular structure of the desmosomal plaque. Proc Natl Acad Sci U S A (2011) 0.95
Quantitative proteome and transcriptome analysis of the archaeon Thermoplasma acidophilum cultured under aerobic and anaerobic conditions. J Proteome Res (2010) 0.95
3D Ultrastructural organization of whole Chlamydomonas reinhardtii cells studied by nanoscale soft x-ray tomography. PLoS One (2012) 0.95
Insights into the molecular organization of the neuron by cryo-electron tomography. J Electron Microsc (Tokyo) (2011) 0.94
NMR studies on the substrate-binding domains of the thermosome: structural plasticity in the protrusion region. J Mol Biol (2004) 0.94
Unraveling the structure of membrane proteins in situ by transfer function corrected cryo-electron tomography. J Struct Biol (2012) 0.94