Published in J Cell Sci on February 14, 2006
Environmental sensing through focal adhesions. Nat Rev Mol Cell Biol (2009) 9.56
Non-muscle myosin II takes centre stage in cell adhesion and migration. Nat Rev Mol Cell Biol (2009) 7.77
Force sensing by mechanical extension of the Src family kinase substrate p130Cas. Cell (2006) 7.35
Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for β-Pix in negative regulation of focal adhesion maturation. Nat Cell Biol (2011) 4.59
Vinculin controls focal adhesion formation by direct interactions with talin and actin. J Cell Biol (2007) 4.28
Mechanical integration of actin and adhesion dynamics in cell migration. Annu Rev Cell Dev Biol (2010) 4.06
Paxillin comes of age. J Cell Sci (2008) 3.57
Myosin II activity regulates vinculin recruitment to focal adhesions through FAK-mediated paxillin phosphorylation. J Cell Biol (2010) 3.56
Integrins in cell migration. Cold Spring Harb Perspect Biol (2011) 3.15
Integrins in cell migration--the actin connection. J Cell Sci (2009) 2.88
Molecular architecture and function of matrix adhesions. Cold Spring Harb Perspect Biol (2011) 2.82
Tension is required but not sufficient for focal adhesion maturation without a stress fiber template. J Cell Biol (2012) 2.12
Mapping the dynamics of shear stress-induced structural changes in endothelial cells. Am J Physiol Cell Physiol (2007) 1.98
Spatial and temporal regulation of focal adhesion kinase activity in living cells. Mol Cell Biol (2007) 1.72
Distinct roles for paxillin and Hic-5 in regulating breast cancer cell morphology, invasion, and metastasis. Mol Biol Cell (2011) 1.54
CCN2 (Connective Tissue Growth Factor) is essential for extracellular matrix production and integrin signaling in chondrocytes. J Cell Commun Signal (2007) 1.24
Force-induced cell polarisation is linked to RhoA-driven microtubule-independent focal-adhesion sliding. J Cell Sci (2009) 1.21
Cross-correlated fluctuation analysis reveals phosphorylation-regulated paxillin-FAK complexes in nascent adhesions. Biophys J (2011) 1.19
A FAK-Cas-Rac-lamellipodin signaling module transduces extracellular matrix stiffness into mechanosensitive cell cycling. Sci Signal (2014) 1.15
P130Cas Src-binding and substrate domains have distinct roles in sustaining focal adhesion disassembly and promoting cell migration. PLoS One (2010) 1.14
Adhesion dynamics at a glance. J Cell Sci (2011) 1.13
Stressing the limits of focal adhesion mechanosensitivity. Curr Opin Cell Biol (2014) 1.05
A focal adhesion protein-based mechanochemical checkpoint regulates cleft progression during branching morphogenesis. Dev Dyn (2011) 1.05
Paxillin and Hic-5 interaction with vinculin is differentially regulated by Rac1 and RhoA. PLoS One (2012) 1.00
VE-cadherin trans-interactions modulate Rac activation and enhancement of lung endothelial barrier by iloprost. J Cell Physiol (2012) 1.00
Fluorescent resonance energy transfer: A tool for probing molecular cell-biomaterial interactions in three dimensions. Biomaterials (2007) 0.96
Modeling the size distribution of focal adhesions. Biophys J (2006) 0.94
Macrophage Migration and Its Regulation by CSF-1. Int J Cell Biol (2012) 0.93
The integrin-ligand interaction regulates adhesion and migration through a molecular clutch. PLoS One (2012) 0.93
Protein tyrosine phosphatase α phosphotyrosyl-789 binds BCAR3 to position Cas for activation at integrin-mediated focal adhesions. Mol Cell Biol (2012) 0.92
Systems microscopy approaches to understand cancer cell migration and metastasis. Cell Mol Life Sci (2010) 0.89
Combining mechanical and optical approaches to dissect cellular mechanobiology. J Biomech (2009) 0.86
Signaling network triggers and membrane physical properties control the actin cytoskeleton-driven isotropic phase of cell spreading. Biophys J (2011) 0.85
Focal adhesions in osteoneogenesis. Proc Inst Mech Eng H (2010) 0.82
Substrate engagement of integrins α5β1 and αvβ3 is necessary, but not sufficient, for high directional persistence in migration on fibronectin. Sci Rep (2016) 0.82
Modulation of FAK and Src adhesion signaling occurs independently of adhesion complex composition. J Cell Biol (2016) 0.81
Gene expression profiling of early-phase Sjögren's syndrome in C57BL/6.NOD-Aec1Aec2 mice identifies focal adhesion maturation associated with infiltrating leukocytes. Invest Ophthalmol Vis Sci (2011) 0.81
A ligand-independent integrin β1 mechanosensory complex guides spindle orientation. Nat Commun (2016) 0.80
GNA13 loss in germinal center B cells leads to impaired apoptosis and promotes lymphoma in vivo. Blood (2016) 0.78
Molecular mechanisms of mechanotransduction in integrin-mediated cell-matrix adhesion. Exp Cell Res (2016) 0.78
Monitoring the cytoskeletal EGF response in live gastric carcinoma cells. PLoS One (2012) 0.78
Fluorescence fluctuation approaches to the study of adhesion and signaling. Methods Enzymol (2013) 0.77
Interaction of crk with Myosin-1c participates in fibronectin-induced cell spreading. Int J Biol Sci (2013) 0.77
Imaging the boundaries-innovative tools for microscopy of living cells and real-time imaging. J Chem Biol (2008) 0.76
Functional atlas of the integrin adhesome. Nat Cell Biol (2007) 6.89
Adhesion-dependent cell mechanosensitivity. Annu Rev Cell Dev Biol (2003) 6.08
Early molecular events in the assembly of matrix adhesions at the leading edge of migrating cells. J Cell Sci (2003) 4.85
A paxillin tyrosine phosphorylation switch regulates the assembly and form of cell-matrix adhesions. J Cell Sci (2006) 3.71
Cell spreading and focal adhesion dynamics are regulated by spacing of integrin ligands. Biophys J (2007) 3.57
Adhesion-mediated mechanosensitivity: a time to experiment, and a time to theorize. Curr Opin Cell Biol (2006) 3.21
Exploring the neighborhood: adhesion-coupled cell mechanosensors. Cell (2002) 3.15
Fibroblast polarization is a matrix-rigidity-dependent process controlled by focal adhesion mechanosensing. Nat Cell Biol (2011) 2.54
Focal adhesions as mechanosensors: a physical mechanism. Proc Natl Acad Sci U S A (2005) 2.43
Fast live simultaneous multiwavelength four-dimensional optical microscopy. Proc Natl Acad Sci U S A (2010) 2.17
The switchable integrin adhesome. J Cell Sci (2010) 2.12
How do microtubules guide migrating cells? Nat Rev Mol Cell Biol (2002) 1.93
Cell mechanosensitivity controls the anisotropy of focal adhesions. Proc Natl Acad Sci U S A (2004) 1.85
Lamellipodium extension and cadherin adhesion: two cell responses to cadherin activation relying on distinct signalling pathways. J Cell Sci (2003) 1.72
Dissecting the molecular architecture of integrin adhesion sites by cryo-electron tomography. Nat Cell Biol (2010) 1.72
Supramolecular crafting of cell adhesion. Biomaterials (2007) 1.66
Early molecular events in the assembly of the focal adhesion-stress fiber complex during fibroblast spreading. Cell Motil Cytoskeleton (2004) 1.59
p120 catenin regulates lamellipodial dynamics and cell adhesion in cooperation with cortactin. Proc Natl Acad Sci U S A (2007) 1.59
Dynamic regulation of the structure and functions of integrin adhesions. Dev Cell (2013) 1.57
Actomyosin-generated tension controls the molecular kinetics of focal adhesions. J Cell Sci (2011) 1.57
Regulation of microtubule dynamics by inhibition of the tubulin deacetylase HDAC6. J Cell Sci (2009) 1.55
Regulation of S33/S37 phosphorylated beta-catenin in normal and transformed cells. J Cell Sci (2002) 1.50
A role for the juxtamembrane cytoplasm in the molecular dynamics of focal adhesions. PLoS One (2009) 1.50
Polarized downregulation of the paxillin-p130CAS-Rac1 pathway induced by shear flow. J Cell Sci (2005) 1.49
Involvement of the Src-cortactin pathway in podosome formation and turnover during polarization of cultured osteoclasts. J Cell Sci (2006) 1.47
Richardson-Lucy algorithm with total variation regularization for 3D confocal microscope deconvolution. Microsc Res Tech (2006) 1.45
Diverse niches within multiple myeloma bone marrow aspirates affect plasma cell enumeration. Br J Haematol (2006) 1.45
Induction of cell polarization and migration by a gradient of nanoscale variations in adhesive ligand spacing. Nano Lett (2008) 1.43
Heparanase mediates cell adhesion independent of its enzymatic activity. FASEB J (2003) 1.41
Multiparametric analysis of focal adhesion formation by RNAi-mediated gene knockdown. J Cell Biol (2009) 1.36
Live-cell monitoring of tyrosine phosphorylation in focal adhesions following microtubule disruption. J Cell Sci (2003) 1.32
The heel and toe of the cell's foot: a multifaceted approach for understanding the structure and dynamics of focal adhesions. Cell Motil Cytoskeleton (2009) 1.29
The role of the actomyosin system in regulating trabecular fluid outflow. Exp Eye Res (2008) 1.28
Engineering vessel-like networks within multicellular fibrin-based constructs. Biomaterials (2011) 1.28
Organization and adhesive properties of the hyaluronan pericellular coat of chondrocytes and epithelial cells. Biophys J (2003) 1.26
Initial stages of cell-matrix adhesion can be mediated and modulated by cell-surface hyaluronan. Biophys J (2002) 1.26
Spatial and temporal sequence of events in cell adhesion: from molecular recognition to focal adhesion assembly. Chembiochem (2004) 1.21
miRNA-based mechanism for the commitment of multipotent progenitors to a single cellular fate. Proc Natl Acad Sci U S A (2010) 1.19
Nano-topography sensing by osteoclasts. J Cell Sci (2010) 1.19
Quantitative multicolor compositional imaging resolves molecular domains in cell-matrix adhesions. PLoS One (2008) 1.19
Molecular engineering of cellular environments: cell adhesion to nano-digital surfaces. Methods Cell Biol (2007) 1.18
DOCK2 regulates chemokine-triggered lateral lymphocyte motility but not transendothelial migration. Blood (2006) 1.15
Targeting membrane-localized focal adhesion kinase to focal adhesions: roles of tyrosine phosphorylation and SRC family kinases. J Biol Chem (2003) 1.14
Rapid telomere motions in live human cells analyzed by highly time-resolved microscopy. Epigenetics Chromatin (2008) 1.13
Latrunculin B effects on trabecular meshwork and corneal endothelial morphology in monkeys. Exp Eye Res (2005) 1.13
Temperature-sensitive micrometer-thick layers of hyaluronan grafted on microspheres. J Am Chem Soc (2006) 1.13
Activation, processing and trafficking of extracellular heparanase by primary human fibroblasts. J Cell Sci (2002) 1.12
The molecular dynamics of osteoclast adhesions. Eur J Cell Biol (2005) 1.10
Functional and structural reversibility of H-7 effects on the conventional aqueous outflow pathway in monkeys. Exp Eye Res (2004) 1.09
Characterization of a novel GTPase-activating protein associated with focal adhesions and the actin cytoskeleton. J Biol Chem (2004) 1.08
Quantitative analysis of cytoskeletal organization by digital fluorescent microscopy. Cytometry A (2003) 1.08
Human heparanase is localized within lysosomes in a stable form. Exp Cell Res (2002) 1.07
Caldesmon effects on the actin cytoskeleton and cell adhesion in cultured HTM cells. Exp Eye Res (2006) 1.06
Cell interactions with hierarchically structured nano-patterned adhesive surfaces. Soft Matter (2009) 1.05
Caldesmon transgene expression disrupts focal adhesions in HTM cells and increases outflow facility in organ-cultured human and monkey anterior segments. Exp Eye Res (2006) 1.04
Anomalous features of EMT during keratinocyte transformation. PLoS One (2008) 1.03
Signaling from adherens-type junctions. Eur J Cell Biol (2005) 1.02
Involvement of the Rho-mDia1 pathway in the regulation of Golgi complex architecture and dynamics. Mol Biol Cell (2011) 1.01
Attenuation of the p53 response to DNA damage by high cell density. Oncogene (2004) 1.01
A conserved tyrosine in the neck of a fungal kinesin regulates the catalytic motor core. EMBO J (2003) 0.99
Involvement of actin polymerization in podosome dynamics. J Cell Sci (2012) 0.99
Allicin inhibits cell polarization, migration and division via its direct effect on microtubules. Cell Motil Cytoskeleton (2007) 0.98
Signaling function of alpha-catenin in microtubule regulation. Cell Cycle (2008) 0.98
Postexposure immunization with modified vaccinia virus Ankara or conventional Lister vaccine provides solid protection in a murine model of human smallpox. J Infect Dis (2009) 0.97
Development and application of automatic high-resolution light microscopy for cell-based screens. Methods Enzymol (2006) 0.96
Application of microscope-based FRET to study molecular interactions in focal adhesions of live cells. Methods Mol Biol (2005) 0.95
Surface-induced regulation of podosome organization and dynamics in cultured osteoclasts. Chembiochem (2009) 0.93
Effective post-exposure protection against lethal orthopoxviruses infection by vaccinia immune globulin involves induction of adaptive immune response. Vaccine (2009) 0.92
High-throughput screening of cellular features using high-resolution light-microscopy; application for profiling drug effects on cell adhesion. J Struct Biol (2007) 0.92
Dynamic study of the transition from hyaluronan- to integrin-mediated adhesion in chondrocytes. EMBO J (2006) 0.91
Differential effect of actomyosin relaxation on the dynamic properties of focal adhesion proteins. PLoS One (2013) 0.91
Tumor cell migration screen identifies SRPK1 as breast cancer metastasis determinant. J Clin Invest (2015) 0.90
Induction of apoptosis in cultured endothelial cells by a cadherin antagonist peptide: involvement of fibroblast growth factor receptor-mediated signalling. Exp Cell Res (2004) 0.90
Resolving and classifying haematopoietic bone-marrow cell populations by multi-dimensional analysis of flow-cytometry data. Br J Haematol (2005) 0.89
Kinectin-mediated endoplasmic reticulum dynamics supports focal adhesion growth in the cellular lamella. J Cell Sci (2010) 0.89
Enteropathogenic Escherichia coli induces modification of the focal adhesions of infected host cells. Cell Microbiol (2002) 0.89
Identification of novel pro-migratory, cancer-associated genes using quantitative, microscopy-based screening. PLoS One (2008) 0.88
Parametric blind deconvolution for confocal laser scanning microscopy. Conf Proc IEEE Eng Med Biol Soc (2007) 0.87
Substrate adhesion regulates sealing zone architecture and dynamics in cultured osteoclasts. PLoS One (2011) 0.87