Published in Crit Care Med on April 01, 2006
Statins for the Early Treatment of Sepsis (SETS) | NCT00528580
Statins and outcomes in patients admitted to hospital with community acquired pneumonia: population based prospective cohort study. BMJ (2006) 3.62
Rosuvastatin for sepsis-associated acute respiratory distress syndrome. N Engl J Med (2014) 3.39
Iron behaving badly: inappropriate iron chelation as a major contributor to the aetiology of vascular and other progressive inflammatory and degenerative diseases. BMC Med Genomics (2009) 2.36
Retracted Atorvastatin improves survival in septic rats: effect on tissue inflammatory pathway and on insulin signaling. PLoS One (2010) 2.08
Statin treatment and reduced risk of pneumonia in patients with diabetes. Thorax (2006) 1.60
Statins and outcomes in patients with bloodstream infection: a propensity-matched analysis. Crit Care Med (2012) 1.59
In the critically ill patient, diabetes predicts mortality independent of statin therapy but is not associated with acute lung injury: a cohort study. Crit Care Med (2012) 1.53
Statin use and risk of community acquired pneumonia in older people: population based case-control study. BMJ (2009) 1.30
Chronic medical conditions and risk of sepsis. PLoS One (2012) 1.16
Preadmission statin use and one-year mortality among patients in intensive care - a cohort study. Crit Care (2010) 1.07
Antibacterial activity of statins: a comparative study of atorvastatin, simvastatin, and rosuvastatin. Ann Clin Microbiol Antimicrob (2012) 1.06
Existing data sources for clinical epidemiology: The North Denmark Bacteremia Research Database. Clin Epidemiol (2010) 1.06
Statin treatment and mortality in bacterial infections--a systematic review and meta-analysis. PLoS One (2010) 1.05
Statins for community-acquired pneumonia: current state of the science. Eur J Clin Microbiol Infect Dis (2009) 0.99
Systematic review and meta-analysis on the association between outpatient statins use and infectious disease-related mortality. PLoS One (2012) 0.95
Statins are associated with improved outcomes of bloodstream infection in solid-organ transplant recipients. Eur J Clin Microbiol Infect Dis (2009) 0.93
Effect of statin therapy in the outcome of bloodstream infections due to Staphylococcus aureus: a prospective cohort study. PLoS One (2013) 0.93
Effect of statin therapy on mortality from infection and sepsis: a meta-analysis of randomized and observational studies. Crit Care (2014) 0.92
Rationale for and protocol of a multi-national population-based bacteremia surveillance collaborative. BMC Res Notes (2009) 0.90
Statins in the critically ill. Ann Intensive Care (2012) 0.90
Simvastatin enhances protection against Listeria monocytogenes infection in mice by counteracting Listeria-induced phagosomal escape. PLoS One (2013) 0.89
The lesser known effects of statins: benefits on infectious outcomes may be explained by "healthy user" effect. BMJ (2006) 0.87
Chronic Statin Use and Long-Term Rates of Sepsis: A Population-Based Cohort Study. J Intensive Care Med (2014) 0.85
Statins and Antimicrobial Effects: Simvastatin as a Potential Drug against Staphylococcus aureus Biofilm. PLoS One (2015) 0.85
Effects of discontinuing or continuing ongoing statin therapy in severe sepsis and septic shock: a retrospective cohort study. Crit Care (2011) 0.84
Preinjury statin use is associated with a higher risk of multiple organ failure after injury: a propensity score adjusted analysis. J Trauma (2009) 0.83
Potential of immunomodulatory agents as adjunct host-directed therapies for multidrug-resistant tuberculosis. BMC Med (2016) 0.83
Association between statin therapy and outcomes in critically ill patients: a nested cohort study. BMC Clin Pharmacol (2011) 0.82
Prior statin use and 90-day mortality in Gram-negative and Gram-positive bloodstream infection: a prospective observational study. Eur J Clin Microbiol Infect Dis (2014) 0.81
Emerging therapeutic targets of sepsis-associated acute kidney injury. Semin Nephrol (2015) 0.81
Diet patterns and risk of sepsis in community-dwelling adults: a cohort study. BMC Infect Dis (2015) 0.80
The Effect of Statins Use on the Risk and Outcome of Acute Bacterial Infections in Adult Patients. J Clin Diagn Res (2015) 0.79
The effect of statin therapy on the incidence of infections: a retrospective cohort analysis. Am J Med Sci (2014) 0.79
Effect of statins on outcomes in immunosuppressed patients with bloodstream infection. Eur J Clin Microbiol Infect Dis (2010) 0.79
Statins decrease mortality in Lebanese patients with sepsis: A multicenter study. Pharm Pract (Granada) (2013) 0.78
A new paradigm for clinical trials in antibiotherapy? Can J Infect Dis Med Microbiol (2011) 0.75
Topical Simvastatin as Host-Directed Therapy against Severity of Cutaneous Leishmaniasis in Mice. Sci Rep (2016) 0.75
Statins, fibrates, thiazolidinediones and resveratrol as adjunctive therapies in sepsis: could mitochondria be a common target? Intensive Care Med Exp (2014) 0.75
Statin therapy and infection-related mortality. Crit Care Med (2007) 0.75
Effect of Statins on the Mortality of Bacteremic Patients: A Systematic Review and Meta-analysis of Clinical Trials. N Am J Med Sci (2016) 0.75
The association of prior statin use in septic shock treated with early goal directed therapy. Eur J Emerg Med (2012) 0.75
Simvastatin-induced sphingosine 1-phosphate receptor 1 expression is KLF2-dependent in human lung endothelial cells. Pulm Circ (2017) 0.75
Statin use and mortality in the bacteremic critically ill patient. Crit Care Med (2006) 2.57
Incidence of adenocarcinoma among patients with Barrett's esophagus. N Engl J Med (2011) 8.62
The predictive value of ICD-10 diagnostic coding used to assess Charlson comorbidity index conditions in the population-based Danish National Registry of Patients. BMC Med Res Methodol (2011) 4.54
The Danish Civil Registration System as a tool in epidemiology. Eur J Epidemiol (2014) 4.30
Venous thromboembolism and subsequent hospitalisation due to acute arterial cardiovascular events: a 20-year cohort study. Lancet (2007) 3.66
Cancer risk among statin users: a population-based cohort study. Int J Cancer (2005) 3.50
Modified Mediterranean diet and survival: EPIC-elderly prospective cohort study. BMJ (2005) 3.48
Maternal use of selective serotonin reuptake inhibitors and risk of congenital malformations. Epidemiology (2006) 3.23
Preadmission use of statins and outcomes after hospitalization with pneumonia: population-based cohort study of 29,900 patients. Arch Intern Med (2008) 3.10
Ischemic heart disease in HIV-infected and HIV-uninfected individuals: a population-based cohort study. Clin Infect Dis (2007) 2.69
Combining electronic healthcare databases in Europe to allow for large-scale drug safety monitoring: the EU-ADR Project. Pharmacoepidemiol Drug Saf (2010) 2.57
Increased short- and long-term risk of inflammatory bowel disease after salmonella or campylobacter gastroenteritis. Gastroenterology (2009) 2.57
Statin prescriptions and breast cancer recurrence risk: a Danish nationwide prospective cohort study. J Natl Cancer Inst (2011) 2.27
Stent thrombosis, myocardial infarction, and death after drug-eluting and bare-metal stent coronary interventions. J Am Coll Cardiol (2007) 2.11
Existing data sources for clinical epidemiology: Aarhus University Prescription Database. Clin Epidemiol (2010) 2.10
Registration in the danish hip arthroplasty registry: completeness of total hip arthroplasties and positive predictive value of registered diagnosis and postoperative complications. Acta Orthop Scand (2004) 2.07
Diabetes mellitus and pyogenic liver abscess: risk and prognosis. Clin Infect Dis (2007) 2.01
Improved long-term clinical outcomes in patients with ST-elevation myocardial infarction undergoing remote ischaemic conditioning as an adjunct to primary percutaneous coronary intervention. Eur Heart J (2013) 2.00
Risk of hospitalization for myocardial infarction among users of rofecoxib, celecoxib, and other NSAIDs: a population-based case-control study. Arch Intern Med (2005) 1.98
Diabetes, glycemic control, and risk of hospitalization with pneumonia: a population-based case-control study. Diabetes Care (2008) 1.97
Therapeutic drug use in women with Crohn's disease and birth outcomes: a Danish nationwide cohort study. Am J Gastroenterol (2007) 1.95
Use of glucocorticoids and risk of venous thromboembolism: a nationwide population-based case-control study. JAMA Intern Med (2013) 1.91
Socioeconomic gradient in use of statins among Danish patients: population-based cross-sectional study. Br J Clin Pharmacol (2005) 1.89
Seasonal variation in hospital discharge diagnosis of atrial fibrillation: a population-based study. Epidemiology (2002) 1.85
Disease activity in pregnant women with Crohn's disease and birth outcomes: a regional Danish cohort study. Am J Gastroenterol (2007) 1.85
Predictive value and completeness of the registration of congenital abnormalities in three Danish population-based registries. Scand J Public Health (2003) 1.82
Using electronic health care records for drug safety signal detection: a comparative evaluation of statistical methods. Med Care (2012) 1.82
Existing data sources for clinical epidemiology: The Danish National Database of Reimbursed Prescriptions. Clin Epidemiol (2012) 1.77
Nontuberculous pulmonary mycobacteriosis in Denmark: incidence and prognostic factors. Am J Respir Crit Care Med (2009) 1.73
Prevalence of infective endocarditis in patients with Staphylococcus aureus bacteraemia: the value of screening with echocardiography. Eur J Echocardiogr (2011) 1.72
Thromboembolic risk among Danish children and adults with inflammatory bowel diseases: a population-based nationwide study. Gut (2011) 1.70
Existing data sources for clinical epidemiology: the Danish National Pathology Registry and Data Bank. Clin Epidemiol (2010) 1.66
2-year clinical outcomes after implantation of sirolimus-eluting, paclitaxel-eluting, and bare-metal coronary stents: results from the WDHR (Western Denmark Heart Registry). J Am Coll Cardiol (2009) 1.65
Type 2 diabetes and pneumonia outcomes: a population-based cohort study. Diabetes Care (2007) 1.64
Short-term mortality in relation to age and comorbidity in older adults with community-acquired bacteremia: a population-based cohort study. J Am Geriatr Soc (2008) 1.63
Crohn's disease is a risk factor for preterm birth. Clin Gastroenterol Hepatol (2010) 1.61
Prevalence of hypospadias in Danish boys: a longitudinal study, 1977-2005. Eur Urol (2009) 1.60
Risk of congenital abnormalities in children born to women with ulcerative colitis: a population-based, case-control study. Am J Gastroenterol (2003) 1.60
Cohort profile: the Danish HIV cohort study. Int J Epidemiol (2008) 1.59
Parity and risk of subarachnoid hemorrhage in women: a nested case-control study based on national Swedish registries. Stroke (2003) 1.58
Chronic diseases requiring hospitalization and risk of non-melanoma skin cancers--a population based study from Denmark. J Invest Dermatol (2007) 1.57
A cohort study of antihypertensive medication use and breast cancer among Danish women. Breast Cancer Res Treat (2006) 1.57
Metformin and incident breast cancer among diabetic women: a population-based case-control study in Denmark. Cancer Epidemiol Biomarkers Prev (2010) 1.55
Use of bisphosphonates among women and risk of atrial fibrillation and flutter: population based case-control study. BMJ (2008) 1.54
Seminational surveillance of fungemia in Denmark: notably high rates of fungemia and numbers of isolates with reduced azole susceptibility. J Clin Microbiol (2005) 1.52
Fever of unknown origin and cancer: a population-based study. Lancet Oncol (2005) 1.52
Skin cancer risk among solid organ recipients: a nationwide cohort study in Denmark. Acta Derm Venereol (2010) 1.51
Low-Dose Aspirin or Nonsteroidal Anti-inflammatory Drug Use and Colorectal Cancer Risk: A Population-Based, Case-Control Study. Ann Intern Med (2015) 1.50
Clinical outcome after primary percutaneous coronary intervention with drug-eluting and bare metal stents in patients with ST-segment elevation myocardial infarction. Circ Cardiovasc Interv (2008) 1.49
Fish intake and acute coronary syndrome. Eur Heart J (2009) 1.48
Maternal smoking and risk of hypertrophic infantile pyloric stenosis: 10 year population based cohort study. BMJ (2002) 1.48
CYP2D6 inhibition and breast cancer recurrence in a population-based study in Denmark. J Natl Cancer Inst (2011) 1.47
[Photographic screening for diabetic retinopathy in the county of North Jutland. The first fully digitalized telemedicine-screening clinic]. Ugeskr Laeger (2002) 1.43
Sex- and age-related differences in clinical outcome after primary percutaneous coronary intervention. EuroIntervention (2012) 1.42
Lack of observed association between high plasma osteoprotegerin concentrations and ischemic stroke risk in a healthy population. Clin Chem (2008) 1.41
Nonaspirin nonsteroidal anti-inflammatory drugs and risk of hospitalization for intracerebral hemorrhage: a population-based case-control study. Stroke (2003) 1.40
The impact of comorbidity on survival of Danish colorectal cancer patients from 1995 to 2006--a population-based cohort study. Dis Colon Rectum (2009) 1.39
Incidence of bone metastases and skeletal-related events in breast cancer patients: a population-based cohort study in Denmark. BMC Cancer (2011) 1.38
[Long-term survival rate of patients transfused with leucocyte-depleted and buffy-coat-poor blood during colorectal surgery--secondary publication. An eight-year post-trial follow-up study]. Ugeskr Laeger (2006) 1.38
Optimizing culture methods for diagnosis of prosthetic joint infections: a summary of modifications and improvements reported since 1995. J Med Microbiol (2012) 1.38
Electronic healthcare databases for active drug safety surveillance: is there enough leverage? Pharmacoepidemiol Drug Saf (2012) 1.36
Delay of treatment is associated with advanced stage of rectal cancer but not of colon cancer. Cancer Detect Prev (2006) 1.36
Dietary patterns among older Europeans: the EPIC-Elderly study. Br J Nutr (2005) 1.33
Spread of a methicillin-resistant Staphylococcus aureus ST80-IV clone in a Danish community. Infect Control Hosp Epidemiol (2005) 1.31
The impact of comorbidity and stage on ovarian cancer mortality: a nationwide Danish cohort study. BMC Cancer (2008) 1.31
Improving the immunogenicity of pneumococcal conjugate vaccine in HIV-infected adults with a toll-like receptor 9 agonist adjuvant: a randomized, controlled trial. Clin Infect Dis (2010) 1.30
Total hip arthroplasty in Denmark: incidence of primary operations and revisions during 1996-2002 and estimated future demands. Acta Orthop (2005) 1.29
Use of selective serotonin-reuptake inhibitors during early pregnancy and risk of congenital malformations: updated analysis. Clin Epidemiol (2010) 1.29
The Prevalence of chronic obstructive pulmonary disease among Danes aged 45-84 years: population-based study. COPD (2008) 1.28
Randomized trial of questionnaire length. Epidemiology (2009) 1.27
Diabetes mellitus as a risk and prognostic factor for community-acquired bacteremia due to enterobacteria: a 10-year, population-based study among adults. Clin Infect Dis (2005) 1.27
Tamoxifen treatment and risk of deep venous thrombosis and pulmonary embolism: a Danish population-based cohort study. Cancer (2009) 1.25
Escherichia coli phylogenetic groups are associated with site of infection and level of antibiotic resistance in community-acquired bacteraemia: a 10 year population-based study in Denmark. J Antimicrob Chemother (2009) 1.25
Robustness of genome-wide scanning using archived dried blood spot samples as a DNA source. BMC Genet (2011) 1.25
Low mortality in HIV-infected patients starting highly active antiretroviral therapy: a comparison with the general population. AIDS (2004) 1.24
Congenital heart defects and developmental and other psychiatric disorders: a Danish nationwide cohort study. Circulation (2011) 1.24
The Danish Centre for Strategic Research in Type 2 Diabetes (DD2) study: expected outcome from the DD2 project and two intervention studies. Clin Epidemiol (2012) 1.24
Pre-natal exposure to paracetamol and risk of wheezing and asthma in children: a birth cohort study. Int J Epidemiol (2008) 1.22
Risk factors for revision due to infection after primary total hip arthroplasty. A population-based study of 80,756 primary procedures in the Danish Hip Arthroplasty Registry. Acta Orthop (2010) 1.21
Comparison of stent thrombosis, myocardial infarction, and mortality following drug-eluting versus bare-metal stent coronary intervention in patients with diabetes mellitus. Am J Cardiol (2008) 1.20