PubRank

Edward Abraham

Author PubWeight™ 227.05‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 2001 SCCM/ESICM/ACCP/ATS/SIS International Sepsis Definitions Conference. Crit Care Med 2003 28.68
2 2001 SCCM/ESICM/ACCP/ATS/SIS International Sepsis Definitions Conference. Intensive Care Med 2003 10.39
3 Involvement of toll-like receptors 2 and 4 in cellular activation by high mobility group box 1 protein. J Biol Chem 2003 8.34
4 The CRIT Study: Anemia and blood transfusion in the critically ill--current clinical practice in the United States. Crit Care Med 2004 5.23
5 High mobility group box 1 protein interacts with multiple Toll-like receptors. Am J Physiol Cell Physiol 2005 5.04
6 miR-21 mediates fibrogenic activation of pulmonary fibroblasts and lung fibrosis. J Exp Med 2010 4.71
7 Transfusion-related acute lung injury: definition and review. Crit Care Med 2005 3.98
8 Urine IL-18 is an early diagnostic marker for acute kidney injury and predicts mortality in the intensive care unit. J Am Soc Nephrol 2005 3.38
9 Involvement of reactive oxygen species in Toll-like receptor 4-dependent activation of NF-kappa B. J Immunol 2004 2.89
10 HMGB1 develops enhanced proinflammatory activity by binding to cytokines. J Immunol 2008 2.80
11 miR-147, a microRNA that is induced upon Toll-like receptor stimulation, regulates murine macrophage inflammatory responses. Proc Natl Acad Sci U S A 2009 2.74
12 Activation of gene expression in human neutrophils by high mobility group box 1 protein. Am J Physiol Cell Physiol 2003 2.50
13 IL-32 synergizes with nucleotide oligomerization domain (NOD) 1 and NOD2 ligands for IL-1beta and IL-6 production through a caspase 1-dependent mechanism. Proc Natl Acad Sci U S A 2005 2.46
14 HMGB1 contributes to the development of acute lung injury after hemorrhage. Am J Physiol Lung Cell Mol Physiol 2005 2.21
15 Diagnostic and prognostic implications of endotoxemia in critical illness: results of the MEDIC study. J Infect Dis 2004 2.17
16 Activation of AMPK attenuates neutrophil proinflammatory activity and decreases the severity of acute lung injury. Am J Physiol Lung Cell Mol Physiol 2008 2.15
17 Variant IRAK-1 haplotype is associated with increased nuclear factor-kappaB activation and worse outcomes in sepsis. Am J Respir Crit Care Med 2006 2.05
18 Recombinant human activated protein C reduces human endotoxin-induced pulmonary inflammation via inhibition of neutrophil chemotaxis. Blood 2004 1.95
19 Sepsis. Am J Med 2007 1.93
20 Severe sepsis and septic shock: review of the literature and emergency department management guidelines. Ann Emerg Med 2006 1.82
21 Recombinant human platelet-activating factor acetylhydrolase for treatment of severe sepsis: results of a phase III, multicenter, randomized, double-blind, placebo-controlled, clinical trial. Crit Care Med 2004 1.80
22 Effectiveness of medical resident education in mechanical ventilation. Am J Respir Crit Care Med 2002 1.79
23 Outcome measures for clinical research in sepsis: a report of the 2nd Cambridge Colloquium of the International Sepsis Forum. Crit Care Med 2005 1.77
24 Antiinflammatory effects of hydrogen peroxide in neutrophil activation and acute lung injury. Am J Respir Crit Care Med 2009 1.77
25 LY315920NA/S-5920, a selective inhibitor of group IIA secretory phospholipase A2, fails to improve clinical outcome for patients with severe sepsis. Crit Care Med 2005 1.77
26 HMGB1 inhibits macrophage activity in efferocytosis through binding to the alphavbeta3-integrin. Am J Physiol Cell Physiol 2010 1.75
27 Extracellular superoxide dismutase haplotypes are associated with acute lung injury and mortality. Am J Respir Crit Care Med 2008 1.73
28 Identification of a microRNA signature in renal fibrosis: role of miR-21. Am J Physiol Renal Physiol 2011 1.70
29 HMGB1 is markedly elevated within 6 hours of mechanical trauma in humans. Shock 2009 1.64
30 Beta-adrenergic agonist therapy as a potential treatment for acute lung injury. Am J Respir Crit Care Med 2006 1.63
31 Post-transcriptional regulation of urokinase-type plasminogen activator receptor expression in lipopolysaccharide-induced acute lung injury. Am J Respir Crit Care Med 2008 1.62
32 Participation of the urokinase receptor in neutrophil efferocytosis. Blood 2009 1.62
33 Potential role of high-mobility group box 1 in cystic fibrosis airway disease. Am J Respir Crit Care Med 2008 1.62
34 Mitochondrial respiratory complex I regulates neutrophil activation and severity of lung injury. Am J Respir Crit Care Med 2008 1.61
35 A descriptive evaluation of transfusion practices in patients receiving mechanical ventilation. Chest 2005 1.57
36 Recombinant platelet-activating factor acetylhydrolase to prevent acute respiratory distress syndrome and mortality in severe sepsis: Phase IIb, multicenter, randomized, placebo-controlled, clinical trial. Crit Care Med 2003 1.53
37 Exposure to hydrogen peroxide induces oxidation and activation of AMP-activated protein kinase. J Biol Chem 2010 1.52
38 Reducing mortality in sepsis: new directions. Crit Care 2002 1.52
39 The decline and fate of an iron-induced subarctic phytoplankton bloom. Nature 2004 1.50
40 Genetic polymorphisms and sepsis. Shock 2005 1.50
41 The role of leptin in the development of pulmonary neutrophilia in infection and acute lung injury. Crit Care Med 2014 1.49
42 MicroRNAs in immune response and macrophage polarization. Arterioscler Thromb Vasc Biol 2013 1.48
43 Hemorrhage-induced acute lung injury is TLR-4 dependent. Am J Physiol Regul Integr Comp Physiol 2004 1.48
44 ADDRESS (ADministration of DRotrecogin alfa [activated] in Early stage Severe Sepsis) long-term follow-up: one-year safety and efficacy evaluation. Crit Care Med 2007 1.46
45 High mobility group protein-1 inhibits phagocytosis of apoptotic neutrophils through binding to phosphatidylserine. J Immunol 2008 1.45
46 Participation of miR-200 in pulmonary fibrosis. Am J Pathol 2011 1.43
47 Contribution of high-mobility group box-1 to the development of ventilator-induced lung injury. Am J Respir Crit Care Med 2006 1.42
48 Interleukin-1 receptor-associated kinase (IRAK) -1-mediated NF-kappaB activation requires cytosolic and nuclear activity. FASEB J 2008 1.39
49 Activated protein C inhibits local coagulation after intrapulmonary delivery of endotoxin in humans. Am J Respir Crit Care Med 2005 1.33
50 Anti-high-mobility group box chromosomal protein 1 antibodies improve survival of rats with sepsis. World J Surg 2006 1.30
51 miR-21 regulates chronic hypoxia-induced pulmonary vascular remodeling. Am J Physiol Lung Cell Mol Physiol 2012 1.29
52 The last 100 years of sepsis. Am J Respir Crit Care Med 2005 1.27
53 PAI-1 inhibits neutrophil efferocytosis. Proc Natl Acad Sci U S A 2008 1.27
54 Early alterations in neutrophil activation are associated with outcome in acute lung injury. Am J Respir Crit Care Med 2003 1.27
55 p53 Attenuates lipopolysaccharide-induced NF-kappaB activation and acute lung injury. J Immunol 2009 1.27
56 Involvement of vitronectin in lipopolysaccaride-induced acute lung injury. J Immunol 2007 1.26
57 MicroRNA let-7c regulates macrophage polarization. J Immunol 2013 1.23
58 Intensive insulin therapy in critical illness. Am J Respir Crit Care Med 2005 1.23
59 Phosphoinositide 3-kinase and Akt occupy central roles in inflammatory responses of Toll-like receptor 2-stimulated neutrophils. J Immunol 2004 1.21
60 Role of extracellular superoxide in neutrophil activation: interactions between xanthine oxidase and TLR4 induce proinflammatory cytokine production. Am J Physiol Cell Physiol 2008 1.18
61 AMP-activated protein kinase enhances the phagocytic ability of macrophages and neutrophils. FASEB J 2011 1.17
62 HMGB1 promotes neutrophil extracellular trap formation through interactions with Toll-like receptor 4. Am J Physiol Lung Cell Mol Physiol 2013 1.17
63 Participation of mammalian target of rapamycin complex 1 in Toll-like receptor 2- and 4-induced neutrophil activation and acute lung injury. Am J Respir Cell Mol Biol 2009 1.16
64 miR-145 regulates myofibroblast differentiation and lung fibrosis. FASEB J 2013 1.15
65 Exposure to hydrogen peroxide diminishes NF-kappaB activation, IkappaB-alpha degradation, and proteasome activity in neutrophils. Am J Physiol Cell Physiol 2007 1.14
66 Participation of superoxide in neutrophil activation and cytokine production. Biochim Biophys Acta 2006 1.12
67 Pharmacokinetics of intravenous and oral levofloxacin in critically ill adults in a medical intensive care unit. Pharmacotherapy 2002 1.11
68 Functional and genomic changes induced by alveolar transmigration in human neutrophils. Am J Physiol Lung Cell Mol Physiol 2006 1.09
69 Bone transport in the management of posttraumatic bone defects in the lower extremity. J Trauma 2004 1.09
70 Evidence for extracellular superoxide dismutase as a mediator of hemorrhage-induced lung injury. Am J Physiol Lung Cell Mol Physiol 2003 1.07
71 Toll-like receptors 2 and 4: initiators of non-septic inflammation in critical care medicine? Intensive Care Med 2010 1.07
72 Pharmacokinetics and pharmacodynamics of imipenem during continuous renal replacement therapy in critically ill patients. Antimicrob Agents Chemother 2005 1.07
73 IL-1 regulates in vivo C-X-C chemokine induction and neutrophil sequestration following endotoxemia. J Endotoxin Res 2002 1.05
74 Involvement of PKCalpha/beta in TLR4 and TLR2 dependent activation of NF-kappaB. Cell Signal 2005 1.05
75 HMGB1 and LPS induce distinct patterns of gene expression and activation in neutrophils from patients with sepsis-induced acute lung injury. Intensive Care Med 2007 1.04
76 Participation of the receptor for advanced glycation end products in efferocytosis. J Immunol 2011 1.03
77 miR-125a-5p regulates differential activation of macrophages and inflammation. J Biol Chem 2013 1.02
78 S-glutathionylation of the Rpn2 regulatory subunit inhibits 26 S proteasomal function. J Biol Chem 2009 1.02
79 Toll-like receptor 4 engagement inhibits adenosine 5'-monophosphate-activated protein kinase activation through a high mobility group box 1 protein-dependent mechanism. Mol Med 2012 1.01
80 Participation of mitochondrial respiratory complex III in neutrophil activation and lung injury. Am J Physiol Lung Cell Mol Physiol 2009 1.01
81 Retracted miR-31 is a negative regulator of fibrogenesis and pulmonary fibrosis. FASEB J 2012 0.99
82 Respiratory syncytial virus inhibits lung epithelial Na+ channels by up-regulating inducible nitric-oxide synthase. J Biol Chem 2009 0.99
83 Involvement of SHIP in TLR2-induced neutrophil activation and acute lung injury. J Immunol 2005 0.99
84 The C-terminal acidic tail is responsible for the inhibitory effects of HMGB1 on efferocytosis. J Leukoc Biol 2010 0.97
85 The kringle domain of urokinase-type plasminogen activator potentiates LPS-induced neutrophil activation through interaction with {alpha}V{beta}3 integrins. J Leukoc Biol 2005 0.97
86 Pulmonary edema fluid antioxidants are depressed in acute lung injury. Crit Care Med 2003 0.97
87 The human long noncoding RNA lnc-IL7R regulates the inflammatory response. Eur J Immunol 2014 0.97
88 Modulation of bone marrow-derived neutrophil signaling by H2O2: disparate effects on kinases, NF-kappaB, and cytokine expression. Am J Physiol Cell Physiol 2003 0.96
89 Intracellular HMGB1 negatively regulates efferocytosis. J Immunol 2011 0.94
90 Induction of tissue factor by urokinase in lung epithelial cells and in the lungs. Am J Respir Crit Care Med 2010 0.93
91 Plasminogen activator inhibitor-1 potentiates LPS-induced neutrophil activation through a JNK-mediated pathway. Thromb Haemost 2006 0.93
92 When is a negative phase II trial truly negative? Am J Respir Crit Care Med 2008 0.92
93 Involvement of the urokinase kringle domain in lipopolysaccharide-induced acute lung injury. J Immunol 2006 0.92
94 Extracellular histones inhibit efferocytosis. Mol Med 2012 0.92
95 Variant IL-1 receptor-associated kinase-1 mediates increased NF-kappa B activity. J Immunol 2007 0.92
96 Involvement of phosphatidylinositol 3-kinase gamma in neutrophil apoptosis. Cell Signal 2003 0.92
97 Immunomodulation and sepsis: impact of the pathogen. Shock 2004 0.89
98 Human resistin promotes neutrophil proinflammatory activation and neutrophil extracellular trap formation and increases severity of acute lung injury. J Immunol 2014 0.89
99 Modulation of SCF beta-TrCP-dependent I kappaB alpha ubiquitination by hydrogen peroxide. J Biol Chem 2009 0.88
100 Urokinase-type plasminogen activator inhibits efferocytosis of neutrophils. Am J Respir Crit Care Med 2010 0.88
101 Vitronectin inhibits neutrophil apoptosis through activation of integrin-associated signaling pathways. Am J Respir Cell Mol Biol 2012 0.88
102 Effects of catecholamines on kinase activation in lung neutrophils after hemorrhage or endotoxemia. J Leukoc Biol 2002 0.88
103 Differential activation of RAGE by HMGB1 modulates neutrophil-associated NADPH oxidase activity and bacterial killing. Am J Physiol Cell Physiol 2011 0.87
104 Inhibition of neutrophil apoptosis by PAI-1. Am J Physiol Lung Cell Mol Physiol 2011 0.87
105 A clinical evaluation committee assessment of recombinant human tissue factor pathway inhibitor (tifacogin) in patients with severe community-acquired pneumonia. Crit Care 2009 0.86
106 Sepsis: current concepts in intracellular signaling. Int J Biochem Cell Biol 2002 0.86
107 Poly(ADP-ribosyl)ation of high mobility group box 1 (HMGB1) protein enhances inhibition of efferocytosis. Mol Med 2012 0.86
108 Individual LPS responsiveness depends on the variation of toll-like receptor (TLR) expression level. J Microbiol Biotechnol 2007 0.85
109 Association between urokinase haplotypes and outcome from infection-associated acute lung injury. Intensive Care Med 2007 0.84
110 Association between IL-32 genotypes and outcome in infection-associated acute lung injury. Crit Care 2011 0.84
111 Derivation of a myeloid cell-binding adenovirus for gene therapy of inflammation. PLoS One 2012 0.84
112 Anemia and blood transfusion in trauma patients admitted to the intensive care unit. J Trauma 2003 0.84
113 Influence of enrollment sequence effect on observed outcomes in the ADDRESS and PROWESS studies of drotrecogin alfa (activated) in patients with severe sepsis. Crit Care 2008 0.83
114 Human models of endotoxemia and recombinant human activated protein C. Crit Care Med 2004 0.82
115 Elevated levels of NO are localized to distal airways in asthma. Free Radic Biol Med 2011 0.82
116 Corticosteroids and septic shock. JAMA 2002 0.81
117 Alterations in the human lung proteome with lipopolysaccharide. BMC Pulm Med 2009 0.81
118 Vitronectin inhibits efferocytosis through interactions with apoptotic cells as well as with macrophages. J Immunol 2013 0.81
119 Identification of TLT2 as an engulfment receptor for apoptotic cells. J Immunol 2012 0.80
120 Year in review 2007: Critical Care--multiple organ failure and sepsis. Crit Care 2008 0.80
121 Controversies in sepsis clinical trials: proceedings of a meeting of the International Sepsis Forum, Lausanne, Switzerland, September 29, 2001. J Crit Care 2006 0.80
122 Cystic fibrosis, pediatrics, control of breathing, pulmonary physiology and anatomy, and surfactant biology in AJRCCM in 2004. Am J Respir Crit Care Med 2005 0.80
123 Critical care in AJRCCM 2004. Am J Respir Crit Care Med 2005 0.80
124 Does blocking cytokines in sepsis work? Am J Respir Crit Care Med 2002 0.80
125 Toward new paradigms in critical care research. Crit Care Med 2009 0.79
126 Community-acquired pneumonia and sepsis. Clin Chest Med 2005 0.79
127 Similarity-based multimarker association tests for continuous traits. Ann Hum Genet 2012 0.79
128 Innate immune dysfunction in trauma patients: from pathophysiology to treatment. Anesthesiology 2012 0.79
129 Lipopolysaccharide-induced neutrophil gene expression under in vivo or in vitro conditions. Chest 2002 0.78
130 The dichotomy of inhibiting nuclear factor kappa-B in pneumonia. Crit Care 2013 0.78
131 Allergic rhinitis, asthma, airway biology, and chronic obstructive pulmonary disease in AJRCCM in 2004. Am J Respir Crit Care Med 2005 0.78
132 The ATS journals' policy on image manipulation. Proc Am Thorac Soc 2008 0.78
133 Working Group on Trauma Research Program summary report: National Heart Lung Blood Institute (NHLBI), National Institute of General Medical Sciences (NIGMS), and National Institute of Neurological Disorders and Stroke (NINDS) of the National Institutes of Health (NIH), and the Department of Defense (DOD). J Trauma 2004 0.77
134 High cytokine levels at admission are associated with fatal outcome in patients with necrotizing fasciitis. Eur Cytokine Netw 2004 0.77
135 New approaches to the treatment of sepsis. Clin Chest Med 2003 0.77
136 International integrated database for the evaluation of severe sepsis and drotrecogin alfa (activated) therapy: 28-day survival and safety. J Crit Care 2007 0.77
137 The receptor for urokinase regulates TLR2 mediated inflammatory responses in neutrophils. PLoS One 2011 0.77
138 It's all in the genes: moving toward precision medicine in critical illness. Crit Care Med 2013 0.77
139 Tuberculosis, nontuberculous lung infection, pleural disorders, pulmonary function, respiratory muscles, occupational lung disease, pulmonary infections, and social issues in AJRCCM in 2004. Am J Respir Crit Care Med 2005 0.76
140 Year in review in Critical Care, 2004: sepsis and multi-organ failure. Crit Care 2005 0.76
141 The ATS Journals' policy on image manipulation. Am J Respir Cell Mol Biol 2008 0.76
142 Identifying patients with idiopathic pulmonary fibrosis: quality or quantity? Am J Respir Crit Care Med 2007 0.75
143 Glucose-6-phosphate dehydrogenase and sepsis: the jury is still out. Crit Care Med 2007 0.75
144 Environmental health and the AJRCCM. Am J Respir Crit Care Med 2005 0.75
145 Anticoagulants for acute lung injury: barking up the wrong tree. Crit Care Med 2009 0.75
146 Do coagulation abnormalities contribute to sepsis associated organ failure? Crit Care Med 2006 0.75
147 Interstitial lung disease, lung cancer, lung transplantation, pulmonary vascular disorders, and sleep-disordered breathing in AJRCCM in 2004. Am J Respir Crit Care Med 2005 0.75
148 The unintended consequences of noble intentions to inform. Proc Am Thorac Soc 2005 0.75
149 The NIH Public Access Policy and ATS journals. Am J Respir Crit Care Med 2005 0.75
150 Changes in NIH review procedures: strengths and weaknesses. Am J Respir Cell Mol Biol 2009 0.75
151 Progress report on the AJRCCM: continued growth and evolution for the journal. Am J Respir Crit Care Med 2006 0.75
152 Talectomy by Medial Surgical Approach for Congenital Vertical Talus in Arthrogryposis Multiplex Congenita. Orthopedics 2020 0.75
153 A fond farewell to a most remarkable experience. Am J Respir Crit Care Med 2009 0.75
154 The NIH Public Access Policy and ATS journals. Proc Am Thorac Soc 2005 0.75
155 Changes in NIH review procedures: strengths and weaknesses. Am J Respir Crit Care Med 2009 0.75